UHSP Collections (University of Health Sciences and Pharmacy)
Not a member yet
1490 research outputs found
Sort by
Antecedents and consequences of medical students\u27 moral decision making during professionalism dilemmas
No full textMedical students often experience professionalism dilemmas (which differ from ethical dilemmas) wherein students sometimes witness and/or participate in patient safety, dignity, and consent lapses. When faced with such dilemmas, students make moral decisions. If students\u27 action (or inaction) runs counter to their perceived moral values-often due to organizational constraints or power hierarchies-they can suffer moral distress, burnout, or a desire to leave the profession. If moral transgressions are rationalized as being for the greater good, moral distress can decrease as dilemmas are experienced more frequently (habituation); if no learner benefit is seen, distress can increase with greater exposure to dilemmas (disturbance). We suggest how medical educators can support students\u27 understandings of ethical dilemmas and facilitate their habits of enacting professionalism: by modeling appropriate resistance behaviors
Fume Hood Testing and Reporting Protocol
No full textTo ensure laboratory fume hoods meet accepted performance criteria established by University of Health Sciences and Pharmacy in St. Louis
Materials of Trade Exemption MOT Transporting Chemicals Off Campus
No full textCertain hazardous materials transported by private motor carriers, for the purpose of direct support of their business (e.g. clinical and laboratory research) are exempt from most of the Department of Transportation (DOT) hazardous materials regulations, as long as they adhere to the requirements described in the Materials of Trade (MOT) exception. Ultimately, by reviewing this policy, personnel should gain a better understanding of the MOT requirements and be better prepared to transport hazardous materials for University business. Note: This exemption does not apply to the relocation/movement of laboratories on or between University of Health Sciences and Pharmacy in St. Louis campuses, nor the relocation or movement of hazardous waste
Complement component 3: characterization and association with mastitis resistance in Egyptian water buffalo and cattle
No full textMastitis is an infectious disease of the mammary gland that leads to reduced milk production and change in milk composition. Complement component C3 plays a major role as a central molecule of the complement cascade involving in killing of microorganisms, either directly or in cooperation with phagocytic cells. C3 cDNA were isolated, from Egyptian buffalo and cattle, sequenced and characterized. The C3 cDNA sequences of buffalo and cattle consist of 5025 and 5019 bp, respectively. Buffalo and cattle C3 cDNAs share 99% of sequence identity with each other. The 4986 bp open reading frame in buffalo encodes a putative protein of 1661 amino acids—as in cattle—and includes all the functional domains. Further, analysis of the C3 cDNA sequences detected six novel single-nucleotide polymorphisms (SNPs) in buffalo and three novel SNPs in cattle. The association analysis of the detected SNPs with milk somatic cell score as an indicator of mastitis revealed that the most significant association in buffalo was found in the C \u3eA substitution (ss: 1752816097) in exon 27, whereas in cattle it was in the C \u3eT substitution (ss: 1752816085) in exon 12. Our findings provide preliminary information about the contribution of C3 polymorphisms to mastitis resistance in buffalo and cattle
An analysis of quality improvement education at US colleges of pharmacy
No full textObjective. Analyze quality improvement (QI) education across US pharmacy programs. Methods. This was a two stage cross-sectional study that inspected each accredited school website for published QI curriculum or related content, and e-mailed a questionnaire to each school asking about QI curriculum or content. T-test and chi square were used for analysis with an alpha a priori set at .05. Results. Sixty responses (47% response rate) revealed the least-covered QI topics: quality dashboards / sentinel systems (30%); six-sigma or other QI methodologies (45%); safety and quality measures (57%); Medicare Star measures and payment incentives (58%); and how to implement changes to improve quality (60%). More private institutions covered Adverse Drug Events than public institutions and required a dedicated QI class; however, required QI projects were more often reported by public institutions. Conclusion. Despite the need for pharmacists to understand QI, it is not covered well in school curricula
Tigecycline-induced coagulopathy
No full textPurpose. A case of coagulopathy in association with tigecycline use is described. Summary. A 63-year-old morbidly obese, wheelchair-bound man was hospitalized for assessment of a possibly infected decubitus ulcer and surgical evaluation for placement of a diverting colostomy; he had been transferred from another facility after initiation of triple-Agent antimicrobial therapy for suspected fecal infection of the ulcer. Based on the results of an ulcer swab culture, the patient\u27s antibiotic regimen was modified (initially to i.v. ertapenem and then to tigecycline on hospital day 10). An International Normalized Ratio (INR) value obtained incidentally within days of tigecycline initiation was slightly elevated (1.2), but no workup was performed at that time. It was determined that the patient would benefit from a colostomy procedure, which was performed about three weeks later (he spent most of the intervening time at a rehabilitation facility, where i.v. tigecycline therapy was continued). During a routine preoperative workup, the patient\u27s INR was found to be elevated (2.1). No identifiable causes for the INR elevation were noted, and the coagulopathy was treated successfully with fresh frozen plasma; the colostomy procedure was uncomplicated. Postoperatively, it was theorized that the development of coagulopathy in this case might have been secondary to tigecycline use. After discontinuation of tigecycline therapy and a switch to an alternative antimicrobial regimen, the patient\u27s INR values normalized within a few days. Conclusion. A patient with a possibly infected decubitus ulcer was treated with tigecycline and subsequently developed a coagulopathy
A structured mentoring program to develop junior faculty into successful co-coordinators of a large multi-instructor pathophysiology course
No full textBackground and purpose To develop and implement a system for junior clinical faculty to become successful course coordinators with the use of a mentoring program and ensure that student performance and satisfaction are maintained at a high level. Educational activity and setting For five years, first-time faculty discussion group leaders in a required large (\u3e225 students) multi-instructor pathophysiology course opted into a structured mentoring program for course coordination in the subsequent year. Program categories included course material development, exam and quiz management, discussion group management, and communication among students, faculty, and staff. Findings Mentors’ previous coordination experience ranged from a few years to over a decade. Faculty participants included three second-year faculty. Each participant successfully undertook a full co-coordinator role the following year. Subsequently, each then became a lead mentor the following year for new participants. Exam quality/reliability statistics were sustained at a high level, course evaluations and student performance improved throughout the program, and all mentor/mentee reflections demonstrated a positive and impactful experience. Discussion and summary Course coordination can be a small percentage of clinical faculty workload, yet is a significant time commitment. Pharmacy resident certificate or new faculty academy programs often do not include course coordination, which is a vital, higher level function/role. Structured mentoring early in professional career of junior faculty aids in the assumption of pedagogical leadership roles, while also developing mentoring skills of mid-level faculty
Hazard Communication Program
No full textThe Occupational Safety and Health Administration (OSHA) has promulgated its Hazard Communication Standard (29CFR 1910.1200) to ensure that the hazards of all chemicals are evaluated, and that information is then transmitted to affected employers and employees in the manufacturing sector.
This Hazard Communication Program (HCP) will be used to make our employees more aware of the safety and health hazards associated with chemical substances produced, used, or transported through our facilities. This HCP is complimentary to the Chemical Hygiene Plan and will apply to all facilities that are not chemical research laboratories, including, but not limited to maintenance, security, custodial services, clinical offices, procedure rooms, clinical laboratories and clerical/administrative staff. This plan will follow the requirements in the 2012 revision of the OSHA Hazard Communication Standard to be consistent with the United Nations Globally Harmonized System (GHS) of Classification of Labeling of Chemicals located in Appendix A of this Plan.
It is our desire to incorporate existing programs such as, but not limited to, area/personnel monitoring and sampling; the respiratory protection program; the hazardous waste management program; the chemical spill plan; the radiation safety program; the fire safety program; the existing work rules; and the implementation of new safety work rules, into this HCP. In the event of overlapping or contradictory statements the more stringent shall apply. It is our belief that this HCP will provide the incentive to improve work practices, increase employee use of personal protective equipment and other safety devices, and to follow precautionary measures when handling or using hazardous chemicals.
This policy applies to all UHSP contractors, faculty, staff, visiting scientists, postdoctoral fellows, students, scholars, and any other person working at or for the University