UHSP Collections (University of Health Sciences and Pharmacy)
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Exploring the Serotonergic Potential of Kratom Alkaloids: Structure-Based Design and Semi-Synthesis of 5-HT1A Receptor Modulators
No full textAsthma control and associated risk factors among adults with current asthma: Findings from 2019 behavioral risk factor surveillance system asthma call-back survey
No full textBackground: Despite the availability of effective treatments, many adults with asthma have uncontrolled asthma. Uncontrolled asthma can lead to severe exacerbations. This study aimed to determine the prevalence and predictors of uncontrolled asthma among adults (≥18 years) with current asthma in the United States. Methods: We analyzed the 2019 Behavior Risk Factor Surveillance System Asthma Call-Back Survey data from 27 states. Asthma control status was classified as “well-controlled” or “uncontrolled” according to the National Asthma Education and Prevention guidelines. The study population consisted of 7937 adults (weighted n = 13,793,220) with current asthma. We used multivariable logistic regression models to identify predictors of uncontrolled asthma. Results: Overall, 62 % of adults with asthma reported having uncontrolled asthma, and 26 % had emergency or urgent care visits or hospitalizations in the past year. Potentially modifiable risk factors associated with uncontrolled asthma included cost barriers to asthma-related healthcare (OR = 2.94; 95%CI 1.96–4.40), complementary and alternative medicine use (OR = 1.84; 95%CI 1.45–2.32), current smoking (OR = 2.25; 95%CI 1.48–3.44), obesity (OR = 1.39; 95%CI 1.02–1.89), COPD (OR = 1.98; 95%CI 1.43–2.74), depression (OR = 1.47; 95%CI 1.16–1.88), fair/poor general health (OR = 1.54; 95%CI 1.14–2.07), household income \u3c$15,000 (OR = 2.59; 95%CI 1.42–4.71), and less than high school education (OR = 2.59; 95%CI 1.42–4.71). Non-modifiable risk factor was Hispanic ethnicity (OR = 1.73; 95%CI 1.09–2.73). Conclusion: Our findings suggest that uncontrolled asthma is common among adults and can be impacted by several factors. Effective asthma control programs are needed to improve asthma management and reduce unnecessary healthcare utilization
Best practices for supporting and improving pharmacy resident research and quality improvement projects
No full textThe 2023 ACCP Research Affairs Committee was charged with developing a commentary to address best practices in pharmacy resident research and quality improvement projects and to consider methods to overcome the challenges encountered in conducting these projects. Literature regarding best practices was evaluated, and approaches were recommended that might help (1) advance the value of the projects to stakeholders; (2) overcome limited preparation for research by residents and mentors, including writing skills and dissemination experience; (3) overcome challenges related to resources (e.g., time and mentors); and (4) avoid burnout among residents and mentors. Although there are many challenges to completing projects and disseminating the results, studies have provided useful recommendations to help circumvent the barriers
Evaluation of a hybrid medication synchronization training module for pharmacy technicians
No full textBackground: Medication synchronization involves coordinating a patient\u27s medications to a single date each month. Medication synchronization programs close gaps in care and improve adherence compared with automatic refill-processing programs. Patients are 2-6 times more adherent to medications when enrolled in a medication synchronization program. Medication synchronization has historically been driven by pharmacists; however, pharmacy technicians are in a unique position to logistically run this service. Objective: This study aimed to develop a training program for pharmacy technicians regarding medication synchronization and assess changes in knowledge and confidence before and after implementing a training program. Practice description: An independent community pharmacy in North Carolina. Pharmacists provide medication therapy management, reimbursed clinical services, medication synchronization, and immunizations. Practice innovation: The training program included medication synchronization basics, patient enrollment process, processing a synced patient, and a hands-on practice session. Evaluation methods: Technicians took a pre-training survey assessing knowledge and confidence before immediately completing a one-on-one pharmacist-led training session with a hands-on component regarding medication synchronization. Technicians took the same post-training survey 2 weeks after completing the training session and using medication synchronization in daily workflow. Pre- and post-training scores were assessed using a paired samples t test. Results: Ten technicians completed the training program; 40% of the technicians were certified and 30% were enrolled in a PharmD program. The mean pre-training knowledge score was 78% (7.1 of 9 points), the mean post-training knowledge score was 92% (8.3 of 9 points), and the mean difference between the pre- and post-training knowledge scores was 13.4% (1.2 points), with a statistically significant difference (P = 0.0026). Confidence with conducting a medication synchronization call increased from 7.2 to 9.6 on a 10-point Likert scale, and confidence scores increased regarding incorporating medication synchronization into workflow from 6.9 to 8.7. Conclusion: The standardized technician training program increased knowledge and confidence in technicians regarding managing a medication synchronization program
Residential Life Professional Staff Partner Residency Policy
No full textThis policy aims to outline guidelines and procedures for UHSP Residential Life professional staff (Live-In Staff member) who wish to have their spouse/partner reside with them on campus. It ensures fairness, transparency, and compliance with relevant regulations while supporting the well-being and effectiveness of staff members in their roles
Reconsidering Pharmacy: We Need to Turn Career Regret into Career Options
No full textDeclining interest in pharmacy as a career is a growing concern. This commentary investigates the factors contributing to career regret among pharmacy graduates, based on data from the American Association of Colleges of Pharmacy (AACP) National Graduating Student Survey. We identify three key contributing factors: workplace environment, professional identity formation, and marketing of the Doctor of Pharmacy degree. We argue that students\u27 observe, in many work environments, a lack of autonomy, repetitive tasks, and unfulfilling work. This leads to diminished job satisfaction and disillusionment. Additionally, marketing tactics and curricular structures can inadvertently contribute to career regret. We propose potential interventions, emphasizing the need for improved working conditions, more versatile roles in pharmacy, and enhanced career development services within colleges / schools of pharmacy. Additional research is needed to fully understand career regret and steps that academic institutions can proactively take to mitigate career dissatisfaction among their graduates
The mediating role of coping styles in the relationship between fear of COVID-19 and mental health problems: a cross-sectional study among nurses
No full textFear of being infected by coronavirus disease 2019 (COVID-19) could trigger mental health problems among nurses at the frontline. In such a situation, coping strategies are needed to deal with the imminent threat. The purpose of this study was to test the mediating effects of coping on relationships of fear of COVID-19 with anxiety, depression and post-traumatic syndrome among nurses who were in contact with COVID-19 patients. A cross-sectional and correlational research design was used to recruit a sample of 278 nurses who treated COVID-19 patients in four government referral hospitals in Indonesia. A bootstrap resampling procedure was used to test the significance of the total and specific indirect effects of coping on relationships of Fear of COVID-19 with anxiety, depression and post-traumatic syndrome. The nurses reported moderate levels of fear of COVID-19, considerable anxiety and depression, and a moderate level of coping. We found coping to be significantly negatively correlated with the reported levels of anxiety, depression and post-traumatic syndrome (p \u3c 0.001). Coping mediated relationships of fear of COVID-19 on depression, anxiety and post-traumatic syndrome after controlling for relevant confounders for each dependent variable. This shows that enacting coping mechanisms is important to achieve an adaptive effect on nurses\u27 mental health. Proper assessments and interventions should be tailored and implemented for nurses who have contact with COVID-19 patients to facilitate their use of coping strategies when needed in stressful situations