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Activation increases for incongruent > congruent audiovisual stimuli.
No full textActivation increases for incongruent relative to congruent stimuli (pooled over age groups) are rendered on an inflated canonical brain. Green areas = height threshold p p S2 Data.</p
Overview of study sites.
No full textBackgroundSoil-transmitted helminth infections (STH) are associated with substantial morbidity in low-and-middle-income countries, accounting for 2.7 million disability-adjusted life years annually. Current World Health Organization guidelines recommend controlling STH-associated morbidity through periodic deworming of at-risk populations, including children and women of reproductive age (15–49 years). However, there is increasing interest in community-wide mass drug administration (cMDA) which includes deworming adults who serve as infection reservoirs as a method to improve coverage and possibly to interrupt STH transmission. We investigated determinants of cMDA coverage by comparing high-coverage clusters (HCCs) and low-coverage clusters (LCCs) receiving STH cMDA in three countries.MethodsA convergent mixed-methods design was used to analyze data from HCCs and LCCs in DeWorm3 trial sites in Benin, India, and Malawi following three rounds of cMDA. Qualitative data were collected via 48 community-level focus group discussions. Quantitative data were collected via routine activities nested within the DeWorm3 trial, including annual censuses and coverage surveys. The Consolidated Framework for Implementation Research (CFIR) guided coding, theme development and a rating process to determine the influence of each CFIR construct on cMDA coverage.ResultsOf 23 CFIR constructs evaluated, we identified 11 constructs that differentiated between HCCs and LCCs, indicating they are potential drivers of coverage. Determinants differentiating HCC and LCC include participant experiences with previous community-wide programs, communities’ perceptions of directly observed therapy (DOT), perceptions about the treatment uptake behaviors of neighbors, and women’s agency to make household-level treatment decisions.ConclusionThe convergent mixed-methods study identified barriers and facilitators that may be useful to NTD programs to improve cMDA implementation for STH, increase treatment coverage, and contribute to the successful control or elimination of STH.Trial registrationThe parent trial was registered at clinicaltrials.gov (NCT03014167).</div
GAD-7 anxiety scores over the first two years of the pandemic.
No full textAnxiety scores divided by gender are further stratified by worry about the health effects of COVID-19 in panel A, and by difficulty paying for basic living expenses in panel B. Trendlines show unadjusted mean GAD-7 anxiety scores, with 95% confidence intervals shaded in grey. Counts in both panels show total observations in each gender group, including observations associated with non-informative levels of difficulty paying for basic living expenses (“Prefer not to state”, “Don’t know”), which are omitted in panel B.</p
Fig 6 -
No full textComparison of lesion marker ranges between the two methods: (a) The original image; (b) An image of the lesion manually drawn by experts; (c) DL-based AI-assisted lesion detection method; (d) Manual testing method.</p
Description of the City Resilience Development Index (CRDI) indicator system.
No full textDescription of the City Resilience Development Index (CRDI) indicator system.</p
Distribution of coupling coordination degree index levels.
No full textDistribution of coupling coordination degree index levels.</p
Time trends of the three major CRDI divisions.
No full textWith the increasing uncertainty of urban security, urban resilience construction with risk awareness and bottom-line thinking has become essential for promoting sustainable urban development. This paper measures China’s urban resilience development index (CRDI) based on 284 cities in China (except Tibet) using the entropy method from four dimensions: economic, social, environmental, and infrastructure, and analyzes it by combining coupling coordination degree and barrier factor analysis. We find that: (1) At the national level, CRDI and its sub-dimensions show an increasing trend in time, a decreasing spatial layout from coastal to inland, and a “high-high-low-low” clustering feature in space. (2) At the regional level, the CRDI is from high to low in the east, middle, and west order. The sub-dimensions are from high to low in the order of east, middle, and west for economic, social, and infrastructure resilience and from high to low in the order of east, west, and middle for environmental resilience. (3) To coupling coordination degree, the CRDI index coupling coordination is increasing in time trend but is still on the verge of dissonance. (4) Social resilience is the main obstacle factor. In the indicator layer, human resources, innovation, education, security, living, and environmental protection are the areas where CRDI coordinated development is the key to improvement. Based on the above empirical evidence, this paper proposes countermeasures to optimize urban resilience construction from four perspectives: economic, social, environmental, and infrastructure.</div
Item loadings on each subfactor of main factor 4 (orthogonal rotation).
No full textItem loadings on each subfactor of main factor 4 (orthogonal rotation).</p
Pearson correlation coefficients between scales (computed on factor scores).
No full textPearson correlation coefficients between scales (computed on factor scores).</p
Decision tree model with BAI as dependent variable, and the subscales of RFQ, ETMCQ, ECR, ERQ, and PMS, as independent variables (using CHAID method).
No full textDecision tree model with BAI as dependent variable, and the subscales of RFQ, ETMCQ, ECR, ERQ, and PMS, as independent variables (using CHAID method).</p