Daegu Gyeongbuk Institute of Science and Technology
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비강 외 후각 수용체들의 교모세포종 진행 조절
No full textGlioblastoma, Tumor-associated microglia and macrophages, Odorant receptors, LigandⅠ. INTRODUCTION 1
ⅠⅠ. MATERIALS AND METHODS 7
IⅠⅠ. RESULTS
3.1 The pathophysiological role of OR5V1 in GBM 12
3.1.1 To establish GL261-luc syngeneic mouse model 12
3.1.2 To demonstrate the function of OR5V1 in GBM 14
3.1.3 To investigate the function of microglial-specific OR5V1 in GBM 16
3.1.4 To determine the anti-tumor effect of OR5V1’s agonist in GBM 20
3.2 The pathophysiological role of OR51E2 in GBM 25
3.2.1 To demonstrate the function of OR51E2 in GBM 25
ⅠV. DISCUSSION 29
V. REFERENCES 36MasterdCollectio
A Full SW-HW Demonstration of GEMM Accelerators with RISC-V Instruction Extensions
No full textMany deep learning accelerators have been proposed and designed in both academia and industry for executing deep neural networks with better power efficiency. Recently, many studies focus on developing a system-on-chip including both host processor and accelerators. In this paper, we demonstrate a full software-hardware stack for accelerating deep learning benchmarks using a co-processor attached to RISC-V core. To do so, we extend the RISC-V instruction set and modified the compilation stack to show significant end-to-end performance boost compared to the CPU-only processing scenario. © 2024 IEEE
Functionalized metal-organic framework modified membranes with ultralong cyclability and superior capacity for zinc/bromine flowless batteries
No full textAqueous zinc/bromine flowless batteries (ZBFLBs) are gaining attention as a next-generation energy storage system with the advantages of a cost-effective active material, simple system configuration, high output, high energy density, and high safety. However, the unrestricted crossovers of Br2 and polybromide (Brn−) seriously cause self-discharge and Zn electrode corrosion, limiting the coulombic efficiency (CE) and battery life. An amidated and sulfonated-functional UiO-66 (U-AS) composite membrane is developed to enhance the ZBFLB performance. U-AS contributes to the balanced ion transport of Zn2+ and Br− ions, while the U-AS internal cage and amine group capture Br2/Brn−, suppressing the crossover. The proper hydrophilic domains in the U-AS membrane form well-connected water channels, facilitating ion transport. Thus, the modified membrane induces homogenous Zn deposition and greatly extends the life span of the ZBFLB over 2600 h at 9.7 mA h and 10 mA cm—2 with an excellent CE of 98%. At a higher depth of charge (DOC) of 96.5 mA h, it exhibits CE of 93.6% from complete suppression of Br2/Brn− crossover. Furthermore, we demonstrate the stable operation of a practical ZBFLB even at a high DOC of 40% for 1200 h with 79% CE. This work provides promising strategies for membrane design toward high-performance ZBFLBs. © 2024 The Royal Society of Chemistry.FALSEsciescopu
Development of Robust 2D Image-Based 3D Vertex Transformation Technique for Real-World Environments
No full textThis paper develops a robust 2D image-based 3D vertex transformation technology for real-world environments. We introduce a novel approach to estimating 3D models based on human silhouettes extracted from frontal and side images. This research demonstrates the potential applications of real-time 3D modeling, virtual fitting, and health monitoring. Through data augmentation and network training, we have developed a model that is resilient to the diverse postures and appearances of users. This technique particularly offers advantages in effectively responding to complex variations in real-world settings
A Sustainable Free-Standing Triboelectric Nanogenerator Made of Flexible Composite Film for Brake Pattern Recognition in Automobiles
No full textIn recent years, the automotive industry has made significant progress in integrating multifunctional sensors to improve vehicle performance, safety, and efficiency. As the number of integrated sensors keeps increasing, there is a growing interest in alternative energy sources. Specifically, self-powered sensor systems based on energy harvesting are drawing much attention, with a main focus on sustainability and reducing reliance on typical batteries. This paper demonstrates the use of triboelectric nanogenerators (TENGs) in a computer mouse for efficient energy harvesting and in automobile braking systems for safety applications using SrBi2Ta2O9 (SBTO) perovskite, blended PDMS composite operating in free-standing mode with an interdigitated patterned aluminum electrode. This self-powered sensor is capable of distinguishing between normal and abnormal braking patterns using digital signal processing techniques. It is noteworthy that the addition of 15%wt. of the SBTO in PDMS composite-based TENG delivered 13.5V, 45nA, and an output power of 0.98µW. This new combination of energy harvesting and safety applications enables real-time monitoring and predictive maintenance in the automotive industry. © 2024 Wiley-VCH GmbH.TRUEsciescopu
A systematic study of the evaporation performance of column-type 3D solar evaporators with variations in the surrounding temperatures
No full textInterfacial solar vapor generation has received much attention as a promising solution to the water scarcity problem. Various evaporation systems capable of significant performance have been developed over the past few years, and solar energy-to-vapor limitations can be overcome by adopting the concept of a three-dimensional (3D) evaporator, enabling the use of surrounding energy in the evaporation process. The degree of surrounding energy utilization depends on the temperature difference between the surrounding air and the evaporation surface, and the air temperature in a solar still – which is indispensable in practical applications – is much higher than the ambient temperature. Laboratory-based evaporation experiments involving a group of 3D column-type evaporators with various surrounding air temperatures were conducted systematically using a newly designed system capable of controlling the surrounding air temperature. The evaporation behaviors at elevated temperatures show significant correspondence with those collected from indoor and outdoor evaporation experiments with a solar still. Therefore, the evaporation performance capabilities of 3D evaporators in practical applications using a solar still can be quantitatively evaluated by investigating laboratory-based evaporation experiments at correspondingly elevated surrounding temperatures. © 2024 Elsevier B.V.FALSEsciescopu
Single-cell transcriptomic analysis reveals dynamic activation of cellular signaling pathways regulating beige adipogenesis
Get PDFPDGFRA+ cells have been identified as adipocyte stem cells (ASCs) that differentiate into beige adipocytes in white adipose tissue (WAT) following thermogenic stimuli. To elucidate the molecular heterogeneity of ASCs, we conducted single-cell transcriptomic profiling of PDGFRA+ cells isolated from the inguinal WAT (iWAT) of mice treated with the beta3 adrenergic receptor agonist CL316243. Single-cell RNA-seq revealed nine major clusters, which were categorized into four groups: resting, proliferating, differentiating, and adipogenic factor-expressing cells (AFECs). Trajectory analysis revealed sequential activation of molecular pathways, including the Hedgehog and Notch signaling pathways, during beige adipogenesis. AFECs expressed Dpp4 and did not differentiate into adipocytes in culture or after transplantation. Furthermore, genetic lineage tracing studies indicated that DPP4+ cells did not differentiate into adipocytes in iWAT during CL316243-induced beige adipogenesis. However, high-fat diet feeding led to the recruitment of adipocytes from DPP4+ cells in iWAT. Overall, this study improved our understanding of the dynamic molecular basis of beige adipogenesis and the potential contribution of DPP4+ adipocyte lineages to the pathological expansion of WAT during diet-induced obesity. © The Author(s) 2024.TRUEsciescopuskc
Wireless System Miniaturization Solutions for Ingestible Sensors
No full textIngestible sensors are pivotal in monitoring the gastrointestinal (GI) tract and enhancing comprehension of complex gastrointestinal processes, propelled by sensor technology advancements. They must ensure robust wireless communication from deep within the body while maintaining longevity for comprehensive monitoring. Wireless system miniaturization stands as a promising solution to these challenges. This paper introduces the current state and technical challenges ingestible sensors and their solutions for wireless system miniaturization. The key techniques for further miniaturization include the antenna miniaturization, integration of adaptive impedance matching networks, and the replacement of crystal. Additionally, the paper explores future directions for wireless communication systems to support the continued advancement of ingestible sensor technology.FALSEsciescopuskc
Cooperative Network-Computation Load Balancing Simulator for Vehicular Edge Computing
No full textTo enhance the performance of autonomous driving, recent studies have been incorporating various tasks that require increasingly more computation. As computational demands increase, it is often difficult to achieve timely execution with the limited performance of onboard computing units alone. To address this issue, Vehicle Edge Computing (VEC), which offloads computational workloads to the edge and retrieves the results back to the vehicle, is gaining significant attention. To achieve efficient offloaded analytics via VEC, it is crucial to comprehensively consider both of the computing and network conditions of the V2X systems, as well as the vehicle energy consumption and timely execution. However, current studies have not sufficiently addressed the comprehensive modeling of computational and network loads in these V2X systems. To deal with this, we propose a Cooperative Network-Computation Load Balancing Simulator for VEC. © 2024 IEEE