Open Journal Systems Trinity College Dublin
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Treatment of periodontal disease improves glycaemic control in Type-1 and Type-2 diabetics: a literature review
Get PDFPeriodontal disease and diabetes mellitus are both complex chronic diseases that have a bidirectional intrinsic link. It has been suggested that the chronic inflammation and infection of pre-existing periodontal disease may impair glycaemic control and hasten the development of diabetic complications. Conflicting results have been shown by the limited number of short-term randomised controlled studies carried out to ascertain whether the treatment of periodontal disease contributes to improvement of glycaemic control. High quality reviews have concluded that small but significant improvements can be expected. Glycated haemoglobin (HbA1c), a haemato- logical indicator of hyperglycaemia, is noticeably reduced in Type-2 diabetics who undergo routine scaling/root planing and oral hygiene regimens when compared to such individuals with no periodontal treatment interventions. Regular and appropriate periodontal therapy leading to any improvement in glycaemic control has the potential to make a significant impact on the quality of life for diabetic patients. The aim of this re-view is to discuss the literature supporting these arguments
Old People Are Still Doing It!
Get PDFResearch suggesting that a high pro- portion of men and women remain sexually active well into later life refutes the prevailing illusion that ageing and sexual dysfunction are unequivocally linked. Age related physiological changes do not render a meaningful sexual relationship im- possible or even necessarily difficult. Many of these physiological changes are modifiable. There are various therapeutic options available to pa- tients to achieve maximum sexual capacity in old age.
In this article I review the physiologi- cal sex-related changes that occur as part of the normal ageing process in men and women. I address the effect of illness on sexual function. In addi- tion, I will summarise the attitudes and perceptions of the media and general public towards sexual activ- ity and ageing. An understanding of the sexual changes that accompany the ageing process may help general practitioners and other doctors to give practical and useful advice on sexuality as well as refute the mis- conception that ageing equates to celibacy. A thorough awareness of this aspect of older people’s quality of life can raise meaningful expecta- tions for ageing patients
Multiple Sclerosis – is the Autoimmune Reaction all Smoke and Mirrors?
Get PDFThe most widely accepted hypothesis of MS pathogenesis is the autoimmune hypothesis. Recently, an alternative theory based on neuropathology of acute MS lesions has been proposed that may argue against the autoimmune hypothesis. It suggests that the initial pathology
is oligodendrocyte apoptosis, while the subsequent inflammation that is “autoimmune-like” may in fact be a secondary phenomenon. This new evidence of a potential pathogenesis may have major implications in terms of treatment options. Instead of using Disease Modifying Treatments (DMTs) we can focus on targeting the initial oligodendrogliopathy and therefore halt the progression of disease before it starts
