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Tolerance on campus: the impact of religious commitment and respect among university students
No full textReligious commitment, particularly within Islamic contexts, is often viewed as a guiding framework for promoting values such as tolerance, respect, and social harmony; however, differing interpretations and personal expressions of religiosity can sometimes challenge these ideals, necessitating deeper exploration of how religiosity influences social interactions. The study investigates the relationship between religious commitment and respect for others regarding the levels of tolerance behavior among university students. The study employed a descriptive quantitative cross-sectional survey from June 16 to August 16, 2023, with a sample of 334 enrolled in the College of Sharia at Yarmouk University in Jordan. The survey consists of three main scales: religious commitment, respect for others, and tolerance. Students’ demographic data, including gender, nationality, age group, academic department, and the year of study, were also collected via the questionnaire. The findings highlight significant gender differences in religious commitment, with males demonstrating higher levels than females. While no significant age differences were observed in religious commitment, tolerance varied notably, particularly among the 24-26 age group. The study participants represented a diverse range of countries of origin. A country-wise analysis revealed that students from Thailand have the highest religious commitment, underscoring the influence of cultural contexts. Departmental comparisons showed no significant differences, although the findings highlight that respect for others impacts tolerance, religious commitment and demography have almost no effect as predicted. The findings emphasize the primary role of respect in fostering social harmony, suggesting that future interventions should focus on promoting respect as a fundamental value in Islamic culture to enhance tolerance
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No full textInvestigation of the production of <SUP>152</SUP>Tb and <SUP>155</SUP>Tb terbium radioisotopes with europium targets
No full textIn recent years, terbium radioisotopes have been investigated for their potential therapeutic and diagnostic applications in nuclear medicine. This study aimed to investigate the production of 152\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document}Tb and 155\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document}Tb by alpha-induced reactions in detail, with a specific focus on determining the optimum production parameters and testing existing nuclear models. Given the limited number of experiments conducted on reactions related to terbium isotope production, it is necessary to perform theoretical calculations of cross sections over a wide energy range to gain a detailed understanding of terbium isotope production. To achieve this objective, the cross sections of the 151\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document}Eu(alpha\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document},n)154\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document}Tb reactions were calculated up to 60 MeV using the TALYS computer code with 432 different combinations of optical model parameters, level density, and strength function models. The theoretical reaction cross-section results were compared with the experimental results in the literature. The best input parameters were determined using the Threshold Logic Unit method, and these parameters were used in all isotope production calculations. Once the optimal model combination was determined, the total activity production and isotopic fraction of 152\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document}Tb and 155\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document}Tb isotopes were calculated in detail for beam energies of 17-50 MeV, different irradiation times, and varying 151\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document}Eu and 153\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document}Eu target thicknesses
A biophysical view on novel ternary copper(II) and nickel(II) complexes as trypsin and urease inhibitors
No full textTrypsin and urease are biologically significant enzymes associated with digestive and pathogenic processes and represent key biochemical targets for inflammatory, ulcerative, and bacterial diseases. Designing metal-based inhibitors to modulate their activity is a promising strategy in medicinal inorganic chemistry. In this study, novel copper(II) and nickel(II) Schiff base complexes, [Cu(L)(bpy)] (1), [Cu(L)(phen)] (2), and [Ni(L)(phen)] (3), where L is derived from 5-chlorosalicylaldehyde and methionine, were synthesized and comprehensively characterized by UV–Vis, FTIR, ESI-MS, CHN analysis, and X-ray diffraction. Electronic absorption and fluorescence spectroscopy revealed minor-groove DNA binding and static quenching interactions with trypsin and urease. Molecular docking supported these findings by predicting favourable binding energies and highlighting key π–π stacking and hydrogen-bonding interactions. Antioxidant and enzymatic inhibition assays further indicated that the complexes exhibit notable free-radical scavenging and moderate inhibitory activity toward both enzymes. Taken together, this study provides integrated experimental and computational insights into the binding mechanisms and structure–activity relationships of Cu(II) and Ni(II) Schiff base complexes, offering a biophysical framework and a preliminary basis for future biological and pharmacological evaluations.</p
Targeting AChE and BChE enzymes with novel chalcone-based hybrid compounds containing imidazo[2,1-b][1,3,4]thiadiazole group: An integrated synthesis, characterization,<i> in</i><i> silico</i> and<i> in</i><i> vitro</i> study
No full textIn this study, a series of novel chalcone derivatives bearing an imidazothiadiazole group were synthesized and since they are approved targets in the treatment of Alzheimer's disease, their inhibitory potentials against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were investigated by in silico methods and in vitro experiments. In the initial stage, the syntheses of the compounds were carried out, and the structures of the compounds were confirmed by 1H NMR, 13C NMR, FT-IR and MS and elemental analysis. Subsequently, the AChE and BChE inhibition potentials of these compounds were investigated by in silico techniques, including molecular docking, molecular dynamics simulations and binding free energy calculations. Molecular dynamics simulations and binding free energy calculations suggested that the compounds may have significant potential as AChE and BChE inhibitors. Therefore, in vitro enzyme inhibition assays were also performed, and the results were compared with the reference drugs donepezil and tacrine. It was found that the synthesized compounds have Ki values in the range of 13.45+5.07-102.78+28.04 nM for AChE and 15.34+6.03-116.01+18.76 nM for BChE, while tacrine and donepezil have Ki values of 123.41+16.50 and 87.92+4.12 nM for AChE, and 89.44+16.81 and 73.85+6.02 nM for BChE, respectively, showing that the synthesized compounds could be effective AChE and BChE inhibitors
İzmit Körfezi'nde Deniz Müsilajı Sorunu: Derleme Çalışması
No full textDeniz müsilajı, deniz ekosistemlerinde fitoplanktonların aşırı çoğalması sonucu oluşan organik bir yapıdır ve sonyıllarda Marmara Denizi başta olmak üzere Türkiye denizlerinde ciddi bir çevre sorunu haline gelmiştir. İzmitKörfezi, coğrafi konumu, yarı kapalı yapısı ve yoğun antropojenik baskılar nedeniyle müsilaj oluşumuna karşıson derece hassas bir ekosistemdir. Bu derleme makalede, İzmit Körfezi özelinde müsilaj oluşumunun bilimseltemelleri, tarihsel gelişimi, çevresel ve sosyo-ekonomik etkileri ile mücadele yöntemleri kapsamlı olarak ele alınmaktadır. 2021 yılında yaşanan büyük müsilaj krizi, bölgenin çevresel kırılganlığını ve acil müdahale gereksinimini ortaya koymuştur.Marine mucilage is an organic structure formed as a result of excessive proliferation of phytoplankton in marine ecosystems and has become a serious environmental problem in Turkish seas, particularly in the Sea of Marmara, in recent years. The Gulf of Izmit is an extremely vulnerable ecosystem to mucilage formation due to its geographical location, semi-enclosed structure, and intense anthropogenic pressures. This review article comprehensively addresses the scientificbasis of mucilage formation specific to the Gulf of Izmit, its historical development, environmental and socio-economicimpacts, and management approaches. The major mucilage crisis experienced in 2021 revealed the region's environmentalfragility and the urgent need for intervention. </p
A New Framework for 3D Printing Aerogels with Additives: Hardware and Ink Development
No full textThe 3D printing of functional aerogels, particularly those incorporating additives, represents a transformative approach in materials science, enabling the creation of highly customizable structures with advanced properties. This study introduces a 3D printing methodology for fabricating aerogel structures infused with titanium dioxide (TiO2) nanoparticles, designed to enhance photocatalytic and environmental remediation applications. A commercially available 3D printer was adapted with a custom syringe pump system, allowing precise control over the extrusion of a shear-thinning aerogel ink. The ink formulation, tailored for compatibility with the system, achieved homogeneous dispersion of TiO2 nanoparticles (55-230 nm) within the silica aerogel matrix at 50 wt % relative to silica content. Postprocessing steps, including gelation in ammonia vapor and supercritical CO2 drying, preserved the intricate geometries of printed structures, which achieved a specific surface area of 407 m(2)/g and a density of 0.15 g/cm(3). Rheological analysis demonstrated the ink's suitability for 3D printing, with viscosity decreasing from 10,000 Pas to 1 Pas under shear, enabling smooth extrusion due to shear thinning behavior, and elastic moduli confirming strong structural integrity necessary for retaining printed shapes. This approach enabled 3D printing of aerogel structures with <1 mm precision. It provides a scalable and cost-effective pathway for producing functional aerogels with tailored properties for potential applications in catalysis, thermal insulation, and environmental remediation
Meaning-making through digital storytelling: Experiences of children and adolescents with cancer within Peplau's theory and a hermeneutic approach
No full textPurpose This study aimed to explore the meaning-making processes of children and adolescents with cancer through Digital Storytelling (DS), grounded in Peplau's Interpersonal Relations Theory and a hermeneutic approach. Methods A qualitative study was conducted using a philosophical hermeneutic design in the pediatric hematology and oncology units of a university hospital in western Türkiye. A purposive sample of 17 children/adolescents (n = 17), aged 7–18 years and having received at least one cycle of chemotherapy, participated in a four-session DS program. Data were collected between January and July 2024 through digital stories, semi-structured interviews with children/adolescents and parents, and researcher reflection journals. Hermeneutic analysis was performed, following iterative interpretation of narratives and the hermeneutic circle. Results Participants created 17 digital stories reflecting their cancer experiences. The stories revealed six interrelated themes: (1) Illness and bodily experiences, (2) Social exclusion and societal perceptions, (3) Family relationships and responsibility sharing, (4) Hope, dreams, and future orientation, (5) Social support and friendship, and (6) Knowledge, sharing, and learning from experiences. DS facilitated children's engagement in symptom management, enhanced coping strategies, fostered emotional expression, and strengthened social connectedness. Parents reported increased motivation and improved family communication, while the researcher's reflections indicated mutual meaning-making and professional growth. Conclusion Digital Storytelling, integrated with Peplau's Interpersonal Relations Theory, is an innovative, holistic nursing approach that supports meaning-making, psychosocial adjustment, and symptom management in pediatric oncology care. The findings suggest DS as a feasible therapeutic communication tool for children and adolescents with cancer
Development of Epoxy-Based Adhesive Films Compatible With Oily Metal Surfaces and Investigation of Their Properties
No full textIn this research, epoxy-based adhesive films compatible with oily metal surfaces were developed and characterized. Because epoxy groups in their backbones are compatible with epoxy resins and long-chain aliphatic groups can dissolve oils, epoxy soybean oil (ESO) and C12-C14 alcohol glycidyl ether (MGC) were added to reference adhesive at varying amounts. Seven adhesive film formulations, including a reference adhesive, were prepared to investigate the effects of additives on rheological, thermal, and tensile lap shear strength (TLSS) properties. The addition of ESO notably increased the gelation time at 120 degrees C, whereas using MGC exhibited no significant impact on the gelation time. TGA analysis showed a decrease in the residue content of the cured films incorporating ESO and MGC. FTIR analysis further demonstrated that strong absorption band at 915 cm- 1, attributed to the epoxide ring, was reduced after the curing process. TLSS testing was conducted by applying a reference adhesive film to both cleaned and uncleaned aluminum plates, and adhesive films containing ESO and MGC additives to uncleaned surfaces. Adding 4% ESO to reference formulation provided the same strength as the reference adhesive film applied to cleaned aluminum plates. The results demonstrated that films containing 4% ESO can be used without surface cleaning in applications