1453 research outputs found

    Blockchain Revolution: How Decentralization will Change the World

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    Blockchain technology has been gaining momentum in recent years as a potential disruptor of traditional centralized systems. Its decentralized nature, immutability, and security features have the potential to revolutionize various industries, from finance to healthcare, supply chain management, and beyond. This article explores how blockchain technology works, its core features, and how it can enable decentralization. It also examines some of the key benefits of blockchain, such as increased transparency, security, and efficiency, and highlights some of the challenges and limitations that need to be addressed for widespread adoption. Finally, the article provides insights into how blockchain technology is already being used in real-world applications and its potential to transform society as we know i

    Enhancing Learning in Robot-Child Tutoring with Personalized Timing Strategies

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    This study focuses on optimizing learning in robot-child tutoring by implementing personalized timing strategies. Non-task breaks are commonly used in education to address children's limited attention spans and promote cognitive rejuvenation. Robots offer a unique opportunity to deliver tailored breaks that meet the individual needs of students, thereby enhancing their learning experiences. In this research, we develop an autonomous robot tutoring system that monitors students' performance and administers breaks based on personalized schedules aligned with their progress. Through a field study, we compare the effectiveness of different timing strategies, including a fixed timing approach, a reward strategy that aligns break timing with performance improvements, and a refocus strategy that aligns break timing with performance declines. The results demonstrate that personalized timing strategies significantly optimize learning outcomes in robot-child tutoring compared to the fixed timing strategy. Additionally, we observe immediate benefits, such as increased efficiency and accuracy in completing educational tasks, following personalized breaks. This study highlights the importance of personalized timing in promoting effective learning and offers insights into improving robot-child tutoring experiences

    Àwọn ọ̀dọ́ orílẹ̀-èdè South Africa tí ó ní HIV àti CD4 tó kéré súmọ́ ewu àtiní jẹjẹrẹ gidi gan-an.

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    Yoruba translation of DOI: 10.31730/osf.io/xq6jhA ṣàfikún ọjọ́-orí 15 sí 24 nínú ìwádìí àpawọ́pọ̀ṣe lórí HIV àti jẹjẹrẹ ní orílẹ̀-èdè South Africa, ẹ̀gbé tó tóbi tí ó jẹ́ àyọrísí ìsopọ̀ láàrin òsùwon àyẹ̀wò ajẹmọ́-HIV láti ilé-iṣẹ́ ibùdó àyẹ̀wò ètò-ìlera àpapọ̀ orílẹ̀-èdè àti ibùdó àpapọ̀ àkọsílẹ̀ ìṣẹ̀lẹ̀ jẹjẹrẹ. A ṣàkọsílẹ̀ ìṣẹ̀lẹ̀ àwọn jẹjẹrẹ tí ó wọ́pọ̀ jùlọ. A wo ìkanra láàrin àwọn jẹjẹrẹ náà àti ẹ̀yà-ìbí, ọdún ìbí, àti iye kuulu-ẹ̀jẹ̀ CD4 pẹ̀lú ìṣàmúlò módẹ́ẹ̀lì Cox àti òṣùwòn alátúntò ásáàdì (aHR)

    Za a iya amfani da dabarar X-ray maras gani don taswirar ƙananan gaɓoɓin ƙwari

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    Hausa translation of DOI: 10.31730/osf.io/2urxfƘididdige tsarin numfashi na ƙwari da bambance-bambancensu ya kasance ƙalubale saboda ƙanƙantarsu. A nan muna auna yawan maƙogoron ƙwaro ta amfani da ɗaukar hoton X-ray micro-tomography (µCT) (a haske 15 µm) a kan rayayyun tsutsotsin ƙwaron cerambycid Cacosceles newmannii masu girman jiki mabambanta waɗanda aka yi allurar barci. A cikin wannan takarda mun samar da cikakkun bayanai na bayanan samfur da samfurin 3D don ɗaukar hotuna 12, samar da sabon bayani game da maimaitawa na nazarin hoto da bambance-bambancen halayen maƙogoro da aka samar ta hanyoyi daban-daban na rarraba hoto. Ana bayar da bayanan ƙarar a nan tare da sassan maƙogoro da aka raba a zaman ƙirar 3D

    COVID ANIMATIONS: Bringing film to life (Presentation)

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    Traditional journalists, politicians, elders, and opinion leaders dominated ‘information’ and communications about the pandemic. Scientists were either side-lined, or didn’t know how to communicate the right information they had, had no resources to do it or all the information there was, wasn’t reaching them in time. The ‘COVID ANIMATIONS: Bringing film to life’ project employed a collaborative approach to science engagement and journalism with the aim of bridging the gap between COVID-19 scientific evidence generated and public health messaging. Using science-based community engagement to fight COVID-19 through animations and film journalism. Themes: -Creating COVID-19 community awareness and response through film -Mitigating the negative impact of COVID-19 on; Maternal and child health and HIV/AIDS care servicesThis project was funded by the Covid-19 Africa Rapid Grant Fund and sponsored by the National Research Foundation, the Republic of South Africa, and ViiV Healthcare. It was implemented by the Joint Clinical Research Centre, Uganda National Council of Science and Technology, Picturing Health (a UK NGO producing health-related films and animations), Mbarara University of Science and Technology, Mimbari Development Agency ( a community engagement group), University of Harare, Centre for Sexual Health and HIV AIDS Research ZW, MRC Clinical Trials Unit at UCL

    Abacwaningi bathi igciwane le-COVID-19 lingase liguquke kancane, kwenze ukuthuthukiswa komgomo kube lula

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    Zulu translation of DOI: 10.3390/pathogens9100829Impathamhlaba i-COVID-19 belulokhu luqhubeka kusukela lwaqala ngasekupheleni kukaNovemba 2019 eWuhan, eChina. Ukuqonda nokuqapha ukuguquguquka kofuzo kwegciwane, izici zalo zendawo, nokuzinza kwalo kubaluleke kakhulu ekulawuleni ukusabalala kwesifo futhi ikakhulukazi ekuthuthukisweni komgomo wendawo yonke ohlanganisa zonke izinhlobo ezibhebhethekayo. Kulo mbono, sihlaziye izinhlobo zofuzo ze-SARS-CoV-2 eziphelele ezingama-30,983 ezivela emazweni angama-79 akumazwekazi ayisithupha futhi saqoqwa kusukela zingama-24 kuZibandlela wezi-2019, kuya kumhla ziyi-13 kuNhlaba wezi-2020, ngokusho kwesizindalwazi se-GISAID. Ukuhlaziya kwethu kuveze ubukhona kwezindawo ezihlukile ze-3206, ezinokusabalalisa okufanayo kwezinhlobo zokuguqulwa kwezakhi ezindaweni ezihlukene. Ngokuphawulekayo, imvamisa ephansi yokuguqulwa kwezinguquko eziphindaphindiwe iye yabonwa; izinguquko eziyi-169 kuphela (5.27%) zande ngo-1% kwama-genomes. Nokho, izindawo eziyishumi nane ezinezinguquko zegciwane kakhulu (<10%) sezikhonjiwe ezindaweni ezingafani ezihambisana ne-genome yegciwane; ayisishiyagalombili ku-ORF1ab polyprotein (ku-nsp2, nsp3, isizinda se-transmembrane, i-RdRp, i-helicase, i-exonuclease, ne-endoribonuclease), ama-nucleocapsid protein, kanye ne-protein ngayinye kwamathathu

    An upper bound for the Erd\H{o}s unit distance problem in the plane

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    In this paper, using the method of compression, we prove a stronger upper bound for the Erd\H{o}s unit distance problem in the plane... #find the complete abstract in the attached fil

    Inhibition Characteristics of Peptide Extracts of Four Medicinal Plants on Activities of Bovine Trypsin

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    Aqueous extract of leaves of Momordica charantia, Hymenocardia acida, Lawsonia inermis and fruit of Xylopia aethiopica have been used in sub Saharan Africa in the management of many viral diseases. Their medicinal properties had been reported to be due to their high antioxidant activities, but limited information is available whether these properties are also due to inhibition or modulation of proteases important in the pathology of viral infections. We report the inhibitory characteristics of peptides extracted from these medicinal plants against bovine trypsin, a serine protease. Extraction of the peptides was done using standard procedure and their inhibitory activities were measured against bovine trypsin. Aqueous extract of M. charantia, H. acida, L. inermis and X. aethiopica contain 5.7 ± 0.5 mg/ml, 1.0 ± 0.2 mg/ml, 1.8 ± 0.1 mg/ml and 28.3 ± 4.1 mg/ml of peptides, respectively. Using Nα-benzoyl-DL-arginine 4-nitroanilide (BAPNA) as trypsin substrate, a Km and Vmax of 0.34 mM and 0.6 μmole/min/mg protein obtained, were altered in the presence of the peptide extracts suggesting the extracts modulate trypsin activity. The inhibition was either competitive, non-competitive or mixed-type of non-competitive inhibition. Inhibition constant (Ki) ranging from 81 to 831±120 μg/ml were obtained using Dixon plot with the peptide extract from M. charantia being the most potent. We concluded that the medicinal and antiviral properties of the extracts could also be due to inhibition or modulation of proteases involved in the pathology of viral infection

    The Evolution of Stem as a Concept, in Science Education – A 21st Century Perspective

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    The transition from STEM to STEAM education signifies a profound shift in contemporary pedagogy, acknowledging the need to integrate not just science, technology, engineering, and mathematics but also the arts into the learning process. This transformation is primarily driven by evolving job market demands, necessitating a more comprehensive skill set in students. Practical implications of this shift involve creative teaching techniques and technologies that foster imagination, experiential learning, and interdisciplinary comprehension. However, within the STEAM domain, significant knowledge gaps remain, offering opportunities for further exploration and development. The primary knowledge gap involves framing STEAM from an enactive-ecological viewpoint. While broader STEM and STEAM research is well-established, the application of enactive and ecological theories in the context of STEAM education is largely uncharted territory. Addressing this gap has the potential to enhance STEAM pedagogy by integrating insights from these theories into educational practices. The second gap relates to the technical underpinnings of integrated teaching and learning in STEM/STEAM contexts. Seamless integration of knowledge domains is vital for meaningful learning experiences that transcend traditional disciplinary boundaries. Robust technical foundations are needed, encompassing digital learning ecosystems, interdisciplinary content development, innovative pedagogical frameworks, accessibility, and inclusivity, professional development for educators, data analytics, and assessment, collaborative environments, real-world application, and immersive technologies. The third gap involves the incorporation of mixed reality (XR) as an educational technology approach within the STEAM framework from an enactive-ecological perspective. XR technologies, including augmented reality (AR), virtual reality (VR), and mixed reality, have the potential to greatly enhance STEAM education. However, further research is required to maximize the use of these technologies from an enactive-ecological standpoint, emphasizing active learning, sensorimotor engagement, experiential learning, and contextual understanding. The fourth knowledge gap emphasizes the importance of ongoing research in the STREAM (STEM + Research + Arts) narrative. Research is a cornerstone for advancing our understanding of the efficacy of various pedagogical approaches, the impact of integrating arts into STEM, the role of enactive-ecological theories, the outcomes of immersive technologies, and the development of unified models for interdisciplinary learning. Strong research practices inform evidence-based teaching and consistently enhance STEAM education. Finally, transition from STEM to STREAM is a crucial development in education, equipping students with the skills and knowledge needed to thrive in a rapidly changing world. While this shift promotes innovative teaching methods and technologies, addressing the identified knowledge gaps and prioritizing research are essential to fully realize the potential of STEAM education. Ultimately, it empowers students to excel in a dynamic and complex global landscape while advancing educational practices through empirical research and evidence-based approaches

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