2564 research outputs found
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Provision of emergency obstetric care at secondary level in a conflict setting in a rural area of Afghanistan - is the hospital fulfilling its role?
No full textProvision of Emergency Obstetric and Neonatal Care (EmONC) reduces maternal mortality and should include three components: Basic Emergency Obstetric and Neonatal Care (BEmONC) offered at primary care level, Comprehensive EmONC (CEmONC) at secondary level and a good referral system in-between. In a conflict-affected province of Afghanistan (Khost), we assessed the performance of an Médecins Sans Frontières (MSF) run CEmONC hospital without a primary care and referral system. Performance was assessed in terms of hospital utilisation for obstetric emergencies and quality of obstetric care
Community participation during two mass anti-malarial administrations in Cambodia: lessons from a joint workshop
No full textTwo mass drug administrations (MDA) against falciparum malaria were conducted in 2015-16, one as operational research in northern Cambodia, and the other as a clinical trial in western Cambodia. During an April 2017 workshop in Phnom Penh the field teams from Médecins Sans Frontières and the Mahidol-Oxford Tropical Medicine Research Unit discussed lessons for future MDAs
Breast tuberculosis in men: A systematic review
No full textBreast tuberculosis in male is a rarely reported and poorly described condition
MSF OCA NCD Guidelines version 4
No full textNon-communicable diseases (NCDs) make the largest contribution to mortality both globally and in the majority of low- and middle- income countries (LMICs). Worldwide, NCDs account for 60% (35 million) of global deaths. The major NCDs used to be diseases of affluence; however, the changing epidemiology of NCDs (increasingly affecting low- and middle-income countries) and the changing patterns of refugee crises (away from settings where infectious disease represents the main burden of disease) mean that they now represent an increasing proportion of the cases we see in many MSF projects
Severe acute malnutrition and retrospective all-cause mortality in children under 5 years of age in target areas of Zamfara State, Nigeria: a SMART survey.
No full textResearch Protocol2. OBJECTIVES\ud
\ud
2.1. PRIMARY OBJECTIVES\ud
\ud
To estimate the all-cause mortality rate and proportion of SAM in children under 5 years of age in target areas in Zamfara State.\ud
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2.2. SECONDARY OBJECTIVES\ud
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To determine causes of death\ud
To assess morbidity\ud
To assess health seeking behaviour \ud
To assess food security and nutritional practices\ud
Estimate the prevalence of gingivitis in children <5 years of ag
Improving utilisation of services for sexual and gender-based violence (SGBV): knowledge, attitudes, practices and perceptions (KAP) in Jahangipuri, Delhi India protocol
No full textResearch Protocol2 Research question and objectives \ud
2.1 Research question\ud
To identify factors that could improve SGBV service utilisation and acceptance amongst MSF’s catchment population in Delhi, India\ud
2.2 Primary objective\ud
To understand how to improve utilization of SGBV services for the population in MSF catchment area Delhi, India\ud
2.3 Specific objectives\ud
1. To understand community knowledge related to SGBV, including its consequences, treatment and clinical services \ud
2. To understand attitudes towards health aspects of SGBV\ud
3. To explore practices related to SGBV care seeking pathways, including barriers and enablers affecting service access and uptake\ud
4. To understand which strategies/activities people consider would be effective in improving access and uptake of clinical services by survivors of SGB
Multi-site evaluation of HIV testing algorithms
No full textResearch ProtocolObjectives\ud
3.1 Primary objective\ud
To evaluate the overall and site-specific performance of the diagnostic algorithm performed at 6\ud
MSF African program sites (i.e. using RDT results from the program sites) comparing using the\ud
diagnostic algorithm with ELISA, LIA, EIA-Ag and DNA-PCR as gold standard.\ud
3.2 Secondary objectives\ud
To evaluate the accuracy (sensitivity, specificity and predictive values) of Orgenics\ud
ImmunoComb® II HIV 1&2 Combfirm as an HIV confirmatory test.\ud
To model different HIV RDT testing algorithms in order to define acceptable testing algorithm in\ud
each study setting (i.e. using RDT results from reference laboratory).\ud
To determine the inter-user reliability of RDT testing (i.e. program sites vs. reference laboratory)\ud
To evaluate accuracy of each HIV RDT measured by the sensitivity (SN), specificity (SP) and\ud
predictive values based on the prevalence of each testing centre.\ud
To evaluate the accuracy of HIV testing using DPS samples for quality control purpose in HIV\ud
testing.\ud
To assess whether additional confirmatory testing (i.e. Orgenics ImmunoComb®\ud
II HIV 1&2\ud
Combfirm) improves the accuracy of the diagnostic algorithm used at the different study sites.\ud
To perform a descriptive analysis on the differentiation between HIV 1 and 2 of the\ud
discriminative RDTs
Factors associated with death and loss to follow-up in children on antiretroviral care in Mingalardon Specialist Hospital, Myanmar, 2006-2016
No full textMyanmar National AIDS programme's priority is to improve the survival of all people living with HIV by providing anti-retroviral therapy (ART) care. More than 7200 children (aged <15 years) have been enrolled into ART care from 2005 to 2016. A previous study showed that ~11% children on ART care had either died or were lost to follow-up by 60 months. Factors associated with death and lost-to follow-up (adverse outcomes) have not been previously studied
