2564 research outputs found
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Retrospective mortality survey in the MSF catchment area in Mayendit county, Unity State, South Sudan
No full textResearch ProtocolOBJECTIVES\ud
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2.1. PRIMARY OBJECTIVES\ud
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To estimate retrospectively the crude mortality rate for the total population and for children under five years of age in the MSF catchment area\ud
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2.2. SECONDARY OBJECTIVES\ud
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To describe the population surveyed by sex and age\ud
To measure crude mortality rate for the total population and for children under five years of age \ud
To obtain an indication of the major causes of death, as well as the age and sex distribution of the deceased\ud
To determine the rate of severe and global acute malnutrition in 6-59 month olds;\ud
To identify the most prevalent morbidities in the population in the two weeks preceding the survey;\ud
To gain knowledge of violence-related event
Exploring the experiences of returned Ebola Virus Disease workers from the United Kingdom
No full textResearch ProtocolA brief summary of MSF EVD programmes & workers\ud
MSF has been running EVD programmes including Treatment Centres in affected countries since early 2014, and currently employs 325 international and around 4150 national staff . MSF protocols to deliver care and control transmission, and to ensure and monitor the health of workers, were available, based on experience in previous outbreaks over many years. In the latter part of 2014, other organisations and national governments established programmes in, and/or sent volunteer workers to, affected countries. In parallel, national protocols for the monitoring of returned workers, and the screening of travellers, have been established in many countries.\ud
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MSF international workers have, to date, numbered some [insert] in total. Infection of MSF workers has been relatively rare, being reported in [insert] international workers, and [insert] national workers; [insert] of the latter have died. Most cases in national workers have been attributed to exposures in the community. No cases of infection due to secondary transmission from infected MSF international workers have been identified. [check]. To date, [insert] MSF international workers have returned to the UK; [insert] of these have undertaken more than one mission. No UK returnees have been infected [check]\ud
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Overall aim:\ud
To describe and explore the experiences of UK EVD workers during the period following their return \ud
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Specific objectives:\ud
1. To explore experiences, perceptions, and views of interactions with family and friends\ud
2. To explore experiences, perceptions, and views of interactions with the general public\ud
3. To explore experiences, perceptions, and views of interactions with colleagues and managers in returning to work\ud
4. To explore experiences, perceptions, and views of public opinion and media coverage\ud
5. To explore experiences, perceptions, and views of policy implementation\ud
6. To identify potential lessons, and areas for potential future research, relevant to the management of staff and programme
Body and mind: retention in antiretroviral treatment care is improved by mental health training of care providers in Ethiopia
No full textEthiopia has achieved a high coverage of antiretroviral treatment (ART), but maintaining lifelong care is still a great challenge. Mental illnesses often co-exist with HIV/AIDS and may compromise the retention on ART. In order to improve prolonged retention in ART care, basic training in mental health care was introduced for ART providers, but this hasn't been evaluated yet. The aim of this study was to examine if this training has improved patient retention in care
Standardized Nutrition Surveys
No full textThe guideline starts with the assumption that the need to carry out a nutrition survey, in an area where MSF is working, has been discussed with all decision makers at headquarters and field level. This is stipulated in criterion two of ”surveys based on the standardised intersectional survey protocols, approved by the MSF ERB”. Moreover, it was agreed to perform the nutrition survey to better evaluate the health status of the population living in the MSF catchment area
Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis
No full textThe fixed dose combination of artemether-lumefantrine (AL) is the most widely used treatment for uncomplicated Plasmodium falciparum malaria. Relatively lower cure rates and lumefantrine levels have been reported in young children and in pregnant women during their second and third trimester. The aim of this study was to investigate the pharmacokinetic and pharmacodynamic properties of lumefantrine and the pharmacokinetic properties of its metabolite, desbutyl-lumefantrine, in order to inform optimal dosing regimens in all patient populations
Is there a correlation between malaria incidence and IRS coverage in western Zambezi region, Namibia?
No full textSetting: A comparison of routine Namibia National Malaria Programme data (reported) vs. household survey data (administrative) on indoor residual spraying (IRS) in western Zambezi region, Namibia, for the 2014-2015 malaria season. Objectives: To determine 1) IRS coverage (administrative and reported), 2) its effect on malaria incidence, and 3) reasons for non-uptake of IRS in western Zambezi region, Namibia, for the 2014-2015 malaria season. Design: This was a descriptive study. Results: IRS coverage in western Zambezi region was low, ranging from 42.3% to 52.2% for administrative coverage vs. 45.9-66.7% for reported coverage. There was no significant correlation between IRS coverage and malaria incidence for this region (r = -0.45, P = 0.22). The main reasons for households not being sprayed were that residents were not at home during spraying times or that spray operators did not visit the households. Conclusions: IRS coverage in western Zambezi region, Namibia, was low during the 2014-2015 malaria season because of poor community engagement and awareness of times for spray operations within communities. Higher IRS coverage could be achieved through improved community engagement. Better targeting of the highest risk areas by the use of malaria surveillance will be required to mitigate malaria transmission
Twenty years of home-based palliative care in Malappuram, Kerala, India: a descriptive study of patients and their care-givers
No full textThe well lauded community-based palliative care programme of Kerala, India provides medical and social support, through home-based care, for patients with terminal illness and diseases requiring long-term support. There is, however, limited information on patient characteristics, caregivers and programme performance. This study was carried out to describe: i) the patients enrolled in the programme from 1996 to 2016 and their diagnosis, and ii) the care-giver characteristics and palliative care support from nurses and doctors in a cohort of patients registered during 2013-2015
"Alert-Audit-Act": assessment of surveillance and response strategy for malaria elimination in three low-endemic settings of Myanmar in 2016
No full textMyanmar, a malaria endemic country of Southeast Asia, adopted surveillance and response strategy similar to "1-3-7" Chinese strategy to achieve sub-national elimination in six low-endemic region/states of the country. Among these, Yangon, Bago-East, and Mon region/states have implemented this malaria surveillance and response strategy with modification in 2016. The current study was conducted to assess the case notification, investigation, classification, and response strategy (NICR) in these three states
Highly targeted cholera vaccination campaigns in urban setting are feasible: The experience in Kalemie, Democratic Republic of Congo
No full textOral cholera vaccines are primarily recommended by the World Health Organization for cholera control in endemic countries. However, the number of cholera vaccines currently produced is very limited and examples of OCV use in endemic countries, and especially in urban settings, are scarce. A vaccination campaign was organized by Médecins Sans Frontières and the Ministry of Health in a highly endemic area in the Democratic Republic of Congo. This study aims to describe the vaccine coverage achieved with this highly targeted vaccination campaign and the acceptability among the vaccinated communities
Safety of a heat-stable rotavirus vaccine among children in Niger: Data from a phase 3, randomized, double-blind, placebo-controlled trial
No full textRotavirus remains a major cause of diarrhea among children under 5 years of age. The efficacy of RotaSIIL, a pentavalent rotavirus vaccine, was shown in an event-driven trial in Niger. We describe the two-year safety follow-up of this trial