Journals of Universiti Kuala Lumpur
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Riddles of the Newborn: DiGeorge Syndrome, Imperforate Anus, and the Enigma of Recurrent Infections
DiGeorge syndrome, also recognized as 22q11.2 deletion syndrome, is a prevalent chromosomal microdeletion disorder characterized by atypical development of the third and fourth pharyngeal pouches, with associated consequences for concurrently developing structures. The resulting phenotypic spectrum is notably diverse. This case report depicts a 3-month-old male infant presenting with imperforate anus and recurrent infections. Prenatal ultrasonography showed congenital cardiac defects, mild bilateral hydronephrosis, and polyhydramnios without the inclusion of amniocentesis in the diagnostic process. Clinical examination revealed facial dysmorphism and imperforate anus. Further investigations detected hypocalcaemia, hypoparathyroidism, and cellular immunodeficiency. Echocardiography confirmed the presence of truncus arteriosus. The baby encountered a stormy period in the Neonatal Intensive Care Unit (NICU), complicated by recurrent infections, cardiac failure, and infantile erythroderma, ultimately leading to Pseudomonas aeruginosa septicemic shock. A Fluorescence In Situ Hybridization (FISH) analysis confirmed the presence of a 22q11.2 deletion, establishing the diagnosis of DiGeorge syndrome in this case. The multifaceted clinical presentation underscores the complexity of this syndrome, emphasising the importance of comprehensive evaluation and timely diagnosis for effective management and care
Transient Foetal Bradycardia in Primary Care: A Diagnostic Dilemma and Navigating Decision
Transient foetal bradycardia is a rare occurrence during pregnancy, characterised by brief episodes of bradycardia followed by spontaneous resolution. Nevertheless, it is essential to exclude other causes, including sinus bradycardia, atrioventricular block, or auto-immune disease-related conditions. We report a case involving the incidental finding of transient foetal bradycardia in a 37-year-old woman at 20 weeks of gestation. A brief episode of foetal bradycardia was observed during a routine transabdominal ultrasound, with a heart rate of 82 beats per minute (bpm). After a short period of observation, foetal bradycardia recurred. The case was referred to a Maternal Foetal Medicine Specialist (MFM) in the obstetrics and gynecology department, where foetal echocardiography was conducted. The conclusion was that transient foetal bradycardia was likely secondary to prematurity. Repeated transabdominal ultrasound at 28 weeks of gestation revealed spontaneous resolution of foetal bradycardia. This case report highlights the importance of foetal cardiac surveillance during routine antenatal visits. The lack of access to foetal echocardiography makes it challenging to verify the diagnosis in primary care; hence, collaboration with a tertiary centre is essential
Basal Cell Carcinoma of The Skin Diagnostic Challenges: A Case Report
Basal cell carcinoma (BCC) is the most prevalent skin cancer, with the reported incidence within the country remaining relatively low. This trend may lead to instances where the condition is underestimated, particularly when skin lesions persist over an extended period. Consequently, there is a risk of overlooking the potential for malignant transformation of chronic non-healing ulcers, especially as the emphasis often shifts to treating skin infections, a common complication in patients with comorbid conditions such as diabetes mellitus, which itself is a risk factor for delayed wound healing. Although squamous cell carcinoma (SCC) is the most frequent malignant transformation arising from chronic wounds, this case report highlights BCC as a possibility. We also emphasise the importance of early referral as opposed to delayed intervention, as timely management can significantly impact patient\u27s functional and cosmetic outcomes as well as their psychological well-being and that of their family members
Unraveling the Enigma: A Case Series of Human Pentastomiasis Encounters.
Pentastomiasis is a zoonotic parasitic disease caused by pentastome parasites, typically reported in Africa, the Middle East, and Southeast Asia. The definitive hosts of Armillifer spp. (a subclass of pentastomes) are snakes, lizards, and other reptiles. Humans acquire the infestation incidentally by consuming uncooked, infected snake meat or drinking water contaminated with pentastome ova. We report two cases of human pentastomiasis, an uncommon condition today. This case report aims to provide the latest updates on human pentastomiasis, particularly in Malaysia, and promote awareness among primary healthcare providers
FABRICATION OF RECHARGEABLE SCREWDRIVER FOR SMALL-VOLUME ASSEMBLY PROCESS
This project presents the fabrication and concept of a rechargeable screwdriver that helps people assemble and disassemble items like cupboards, tables or chairs. The rechargeable screwdriver uses rotational motion with a DC rotary motor. The screws can be driven to tighten or loosen by pushing a switch. The product aims to give better accessibility to all generations of age, from young people to teenagers, adults, and senior citizens, as it will be much easier to use and does not require much force. Besides that, this project also discusses the product\u27s sustainability, where the product\u27s material is mainly focused on cheap but usable items and recyclable and reusable items. In conclusion, the developed prototype of an electric screwdriver is handy for many tasks and comes with different tips for different screws. Overall, the screwdriver is safe and easy to use and is expected to last longer than a typical rechargeable screwdriver
DEVELOPMENT AND CONTROL OF SMART INCUBATOR SYSTEM FOR PREMATURE BABIES
Smart incubator systems (SIS) for infants are designed to provide the best possible care for premature and critically ill newborns. It uses advanced technology to monitor and regulate the temperature, humidity, and other environmental factors in the incubator for the neonates. The essential goal of this paper is to build a low-cost, efficient, and dual-powered incubator that saves premature neonates \u27 lives. An open-source Internet of things (IoT) application and an Arduino Nano microcontroller equipped with several sensors are used to remotely monitor and control the environment levels inside an infant incubator. This study examined the effect of temperature and Humidity on the infant incubator control system. It employed a DHT11 Temperature and Humidity sensor, which was processed by an Arduino NANO microcontroller and presented on a PC. The average value of the minimum difference for DHT11 sensor readings was 34°C and 25%, and the average maximum value difference was 37°C and 65%. The DHT11 sensor was found to have lower oscillations and higher accuracy. The BLYNK application server is used to a network so that it is linked to a smartphone and sends notifications to the registered medical staff and parent’s mobile number if any abnormalities are detected. The outcomes of this research have demonstrated that using Thing Speak IoT apps, real-time updated medical records were transmitted to the medical team and parent
DESIGN MICROSTRIP ANTENNA FOR Ka BAND
The Micro-strip patch antenna has become very famous and has attracted much attention towards research because of its light weight, compactness, inexpensiveness, and ability to maintain high performance over a wide range of frequencies. In this paper, the rectangular patch is designed with different parameters like return loss, Voltage Standing Wave Ratio (VSWR), directivity, and radiation pattern in 3-D, and impedance matching is simulated using CST Microwave Studio simulation software. This project presents the design and simulation of a Micro-strip patch antenna operating at 38 GHz for 5G communication. The antenna operates a centre frequency of 38 GHz with a maximum reflection coefficient of -31.305 dB, and a very wide bandwidth of 0.978 GHz. The transmission line of the antenna used is an inset feed. The substrate used is Roger RT5880, which has a dielectric constant of 2.2 and a height of 0.2 mm. The antenna dimensions were calculated and simulated results have been displayed and analyzed using CST Microwave Studio
EVALUATING THE EFFECTIVENESS OF DIGITAL FORENSIC TOOLS IN COMBATING CYBER CRIME: AN ANALYTICAL STUDY BASED ON PREVIOUS RESEARCH
Digital forensic investigations are essential in the fight against cybercrime, particularly in hacking and extortion cases. This study highlights the effectiveness of cutting-edge forensic tools and methodologies in recovering digital evidence and identifying offenders. Building on foundational research, such as Yusof and Othman (2019) and Chung et al. (2017), this work systematically reviews the literature to identify critical gaps and emerging trends in digital forensics. The findings underscore the significant role of digital forensic tools in enhancing evidence recovery and perpetrator identification, addressing challenges noted by Zareen and Ullah (2020) and Alenezi et al. (2021). Continued investment in digital forensic research and the establishment of robust legal frameworks are imperative, as emphasized by Azfar et al. (2016) and Iqbal et al. (2018). Recommendations for future research include expanding the scope of inquiry, scrutinizing legal frameworks, and integrating new technologies. For practitioners, fostering collaboration, providing ongoing training, and creating specialized centers are vital. Ultimately, equipping digital forensic experts with these strategies will enhance their ability to preempt and counteract the challenges posed by cybercriminals, thereby protecting individuals, organizations, and society at large
SOME PHYSICS APPLICATIONS OF THE NEW INTEGRATION
In this work, we apply a new integral transform the Abaoub-Shkheam Transform in solving first and second-order ordinary differential equations with constant coefficients and equations are concerned with a damping mechanical force system and an inductive capacitive electrical circuit in mechanics and electrical circuit problems with initial conditions. Also, we will discuss the applications of the Abaoub-Shkheam Transform in solving the differential equations related to successive radioactive decay of the parent nucleus which is an important subject in nuclear physics. Also included are the formulae for computing the daughter and granddaughter nuclei, as well as instructions for the function of the mechanical system\u27s transfer. 
THE IMPORTANCE OF USING CLOUD COMPUTING SERVICES AND TECHNOLOGIES IN TRACKING STUDENTS\u27 BEHAVIOR WHILE USING ASYNCHRONOUS E-LEARNING PLATFORMS
The problems that different aspects of teaching and learning provide to the education industry are continuous. Teachers and students together always struggle to increase their knowledge due to ongoing technological breakthroughs in education. In order to remain on track and maintain students’ engagement during the COVID-19 epidemic, several educational institutions were compelled to quickly implement such technologies. Students that participate in asynchronous e-learning are by themselves throughout the process of learning. The main effects of this loneliness are dissatisfaction and lack of motivation, which increase the dropout rate. Monitoring a student\u27s behavior while they are learning enables timely intervention. However, the amount of information offered to teachers in the online courses could be excessive. This study has shown the impact of cloud computing and its function in tracking students\u27 behavior throughout the asynchronous e-learning process. We compile student data and perform a questionnaire survey on the relevance of the cloud in asynchronous e-learning. To simplify the components and improve the outcomes, Principal Component Analysis (PCA) was applied. The findings are analyzed using descriptive statistical analysis and Analysis of Variance (ANOVA). The research demonstrates how technology use and improved internet infrastructure have a significant positive influence on learning, enabling studying at anytime and anyplace