HAL Portal Univ Catholille
Not a member yet
19763 research outputs found
Sort by
Opportunités et contraintes de la transmission en viticulture en Occitanie : croisement des perspectives des cédants et des repreneurs
No full textPrix de la meilleure communication sur l’entrepreneuriat et la transmission familiale décerné par le HEC Paris Family Business Center.International audienceIn this research, we analyzed viticulture business transfer by crossing the perspectives of the main actors in wine transmission: buyers, sellers and other stakeholders involved (institutional and experts). We support that an integrated view of this process must focus on buyer-seller couples both in terms of analysis and understanding of motivations and constraints, but also in terms of project monitoring and support. Through a series of 27 semi-structured interviews (buyers, sellers, institutions and experts) and a survey of 44 buyers and sellers, we were able to collect data confirming the complexity of the transmission process and the need to understand it in a comprehensive and dynamic way. The results obtained were discussed in the light of around fifty previous research studies on agricultural transmission in France and internationally. We suggest better consideration of the regional and sectoral specificities of viticulture in Occitanie (consumer crisis, characteristics of the products (brands and stocks) and of the wine-growing land), better integration of the factors of initial reluctance of the sellers and the determinants of the "search for meaning" and professional recognition of the buyers and specific support for the projects through simultaneous monitoring of the buyer-seller duos.Dans cette recherche, nous avons mené une réflexion en croisant les regards des principaux acteurs des transmissions viticoles que sont les cédants, les repreneurs et les autres acteurs impliqués (institutionnels et experts). L’idée principale avancée dans cette recherche est qu’une lecture intégrée de ce processus doit s’intéresser aux couples cédants-repreneurs à la fois en termes d’analyse et de compréhensions des motivations et des freins, mais également en termes de suivis des projets et de leur accompagnement. A travers une série de 27 entretiens semi-directifs (cédants, repreneurs, institutionnels et experts) et une enquête auprès de 44 cédants et repreneurs, nous avons pu recueillir des données confirmant la complexité d’un processus et la nécessité de l’appréhender de manière complète et dynamique. Les résultats obtenus ont été discutés à la lumière d’une cinquantaine de recherches antérieures portant sur les transmissions agricoles en France et à l’international. Ils suggèrent une meilleure prise en compte des spécificités régionales et sectorielles de la viticulture en Occitanie (crise de consommation, caractéristique du produits (marques et stocks) et du foncier viticole), de mieux intégrer les facteurs de réticences de départ des cédants et des déterminants de « quête de sens » et de reconnaissance professionnelle des repreneurs et un accompagnement spécifique des projets par un suivi simultané des duos repreneurs-cédants.Cette communication a reçu le prix de la meilleure communication sur l’entrepreneuriat et la transmission familiale décerné par le HEC Paris Family Business Cente
Bridging Surface Science and van der Waals Engineering: Growth Mechanisms and Assembly of Functional Nanostructures
No full textProf. LOPPACHER Christian, IM2NP - Université Aix-Marseille (rapporteur) Prof. RICHTER Christine, DICO - CY Cergy Paris Université (rapportrice) DR CNRS BORISSOV Andrey, ISMO - Université Paris Saclay (rapporteur) Prof. MASSON Laurence, CINAM - Université Aix-Marseille (examinatrice) DR CEA FIORINI Céline , SPEC – IRAMIS - CEA Saclay (examinatrice) DR CNRS CLAIR Sylvain, IM2NP - Université Aix-Marseille (examinateur) DR CNR DELERUE Christophe, IEMN - Université de Lille (garant)This HDR memoir presents a concise overview of my research activity, from postgraduate studies to my current academic position, with a focus on nanoscience, surface science, and materials science. It begins with the scientific motivations behind the choice of these fields, followed by a summary of the work carried out during successive postdoctoral appointments. These studies primarily address the controlled growth of two-dimensional (2D) organic and inorganic films, as well as one-dimensional (1D) and zero-dimensional (0D) nanostructures, investigated using a broad range of advanced surface-sensitive techniques.These projects laid the conceptual and methodological foundation for my current research and directly inspired its development. My ongoing work builds on the expertise acquired and aims to address long-term goals in the design of adaptive polymers and nanostructured graphenes as versatile platforms for engineering robust 2D layers with tunable, integrated functionalities. The approach involves designing specific functional units at the molecular level and scaling them up through integration into extended 1D and 2D polymeric or graphenic architectures. A central aim of my current projects is to establish precise control over the shape, dimensionality, chirality, and functionality of the resulting nanostructures, and to enable their effective transfer onto targeted substrates for further integration into van der Waals heterostructures and prototypal devices. With this objective, four main research directions have been initiated and are currently in progress: (i) investigating the role of triphenylamine functionalization on the formation of surface-confined organic frameworks (SCOFs); (ii) engineering and probing the physical properties of novel nanoporous graphene structures; (iii) fabricating and studying nanostructured carbon nitrides; and (iv) examining the influence of substrate type on the growth of molecular switch films, with the goal of achieving controllable tuning of properties in the resulting 2D materials.This HDR memoir presents a concise overview of my research activity, from postgraduate studies to my current academic position, with a focus on nanoscience, surface science, and materials science. It begins with the scientific motivations behind the choice of these fields, followed by a summary of the work carried out during successive postdoctoral appointments. These studies primarily address the controlled growth of two-dimensional (2D) organic and inorganic films, as well as one-dimensional (1D) and zero-dimensional (0D) nanostructures, investigated using a broad range of advanced surface-sensitive techniques.These projects laid the conceptual and methodological foundation for my current research and directly inspired its development. My ongoing work builds on the expertise acquired and aims to address long-term goals in the design of adaptive polymers and nanostructured graphenes as versatile platforms for engineering robust 2D layers with tunable, integrated functionalities. The approach involves designing specific functional units at the molecular level and scaling them up through integration into extended 1D and 2D polymeric or graphenic architectures. A central aim of my current projects is to establish precise control over the shape, dimensionality, chirality, and functionality of the resulting nanostructures, and to enable their effective transfer onto targeted substrates for further integration into van der Waals heterostructures and prototypal devices. With this objective, four main research directions have been initiated and are currently in progress: (i) investigating the role of triphenylamine functionalization on the formation of surface-confined organic frameworks (SCOFs); (ii) engineering and probing the physical properties of novel nanoporous graphene structures; (iii) fabricating and studying nanostructured carbon nitrides; and (iv) examining the influence of substrate type on the growth of molecular switch films, with the goal of achieving controllable tuning of properties in the resulting 2D materials
Part Feeding and Internal Transportation Decision Making for a Machinery Manufacturer
No full textInternational audienceBecause of a constant increase in the variety and number of parts required for assembly, part provision to the border of line requires careful orchestration. Therefore, every part must be assigned to the most suitable feeding policy, determining logistical in-house processes, presorting degree, and load carrier sizing. This assignment allows effective space management at the border of line while avoiding unnecessary intralogistics activities. Furthermore, timely part delivery necessitates decisions on vehicle type selection and delivery frequencies. In this research, we adapt an existing optimization model to the specific case of a machinery manufacturing company, validating the model for practical usage. The model aims to achieve cost minimization through optimal part feeding policy and vehicle type selection decisions, considering various constraints related to space availability at the border of line and the capacity of transportation vehicles. Our results reveal that the optimal assignment reduces costs by 56% compared with the company’s current assignment. Although the optimal assignment requires additional capacity investments for the company, we also test various restrictive solutions by adding practically relevant constraints. The latter still results in minimum cost savings of 23%, compared with the current assignment. Besides the cost benefits, the number of different line feeding policies is reduced. This streamlines the process, making it more conducive to automation
Navigating the legal environment of AI (part 1)
No full textIESEG Insights, https://insights.ieseg.fr/en/resource-center/navigating-legal-environment-artificial-intelligence-ai
Identification of Biosynthetic Precursors and Optimization of 7-Hydroxytropolone Bioproduction by Pseudomonas sp. PA14H7
No full textInternational audienceCell-free supernatant of the strain Pseudomonas sp. PA14H7 has previously shown interesting activity against Soft Rot Pectobacteriaceae (SRP), the bacterial pathogen responsible for blackleg and soft rot diseases in potatoes. A deeper understanding of its mode of action is essential to optimize its use as a biocontrol agent. We previously reported that Pseudomonas sp. PA14H7 produces a specialized metabolite, the 7-hydroxytropolone (7-HT), which acts as an iron chelator, limiting the growth of SRP. In this study, we have constructed a Δhts10 deletion mutant of Pseudomonas sp. PA14H7, encoding a putative acyl-CoA dehydrogenase corresponding to the ortholog of orf10 in Pseudomonas donghuensis. We demonstrated that this mutant was deficient in 7-HT biosynthesis, confirming that this molecule is the metabolite responsible for the antagonist activity. After finding a minimum culture medium (MK) allowing the Pseudomonas sp. PA14H7 growth without 7-HT production, we investigated the biosynthetic pathway of this metabolite. We identified phenylalanine and phenylacetic acid as 7-HT precursors and demonstrated that the addition of 150 mg/L of phenylalanine to the MK medium enhanced the 7-HT bioproduction by Pseudomonas sp. PA14H7 up to 30 mg/L. These findings provide new insights into the biosynthesis and regulation of 7-HT, paving the way for the use of Pseudomonas sp. PA14H7 as a biocontrol agent
Cannabis regulation and IP rights in Uruguay
No full textChapter 10International audienceThis chapter provides an analysis of Uruguay's regulatory framework for cannabis liberalization, the first of its kind globally. It explores how Uruguay's approach to IP rights has shaped cannabis research, development, and commercialization. Despite Uruguay's leading role in legalizing recreational, medicinal, and industrial cannabis, the impact of IP rights has been limited. This limitation can be attributed to the small scale of Uruguayan firms and the government's restrictive policies, including a legal monopoly and no-brand policy for recreational cannabis, which reduce economic incentives for intellectual property (IP). The chapter argues that IP rights are most effective in a robust market with effective enforcement mechanisms. Public authorities, such as the IRCCA, have utilized IP rights, holding four plant breeders’ rights (PBRs) for recreational cannabis varieties. The chapter anticipates a gradual increase in IP rights, especially trademarks and PBRs, in the medicinal and industrial cannabis sectors as these markets mature, though the growth will be modest compared to developed countries
A multiscale approach to investigate the impact of thermal fluctuations on crack propagation in fracture and decohesion
No full textInternational audienceIn various physical, biological and technological systems, fracture propagation and decohesion phenomena are widespread. Understanding these processes has broad applications, ranging from classical solid mechanics (e.g., crack propagation) to emerging fields such as advanced materials, nanotechnology, and soft materials like rubber-like substances and biomaterials (e.g., cell adhesion and de-adhesion, DNA denaturation).Experimental findings have already highlighted the important role that thermal fluctuations can play on these phenomena. However, a theoretical investigation of temperature effects remains challenging due to the complexity of the involved physical processes. Thus, despite extensive experimental studies and numerical simulations investigating the interplay between thermal fluctuations and mechanical properties, a comprehensive theoretical framework fully integrating temperature effects is still lacking. In this study we present a first step in this direction, based on a simplified model for the Griffith energy criterion for mode I fracture, extending the classical approach to include thermal fluctuations. The key step in this direction lies in replacing the total mechanical energy by including entropicterms and referring to the free energies. Thuss, by employing tools from equilibrium statistical mechanics, we incorporate entropic effects into the overall energy balance.Furthermore, we adopt a multiscale paradigm by developing both discrete and continuum models. Although intentionally simplified, these models allow for analytical solutions and provide deeper insights into the underlying physics. Our approach effectively captures the energetic competition between elastic deformation, external loading, fracture energy, and entropic contributions.The proposed framework describes not only the scenario where fracture or decohesion propagates from one end but also cases where the broken region forms inside the system, including configurations with multiple fracture bubbles (e.g., multiple bubbles in DNA). In the latter case, we identify solutions where these bubbles merge before complete failure occurs.Finally, our model reveals a classical critical behaviour: the critical load decreases as temperature increases, following the law (1 − T /Tc)^(1/2) . As a direct consequence of temperature effects, we demonstrate that, at the critical temperature Tc , the system undergoes a phase transition, leading to complete rupture without any applied mechanical load
L’engagement en pleine conscience : une étude des effets de la pleine conscience sur l'engagement organisationnel affectif
No full textNational audienc
Ocular surface evaluation in atopic dermatitis patients on dupilumab: A prospective observational study
No full textInternational audiencePurpose. - To describe the ocular surface findings in atopic dermatitis patients treated with dupilumab. Method. - This is an observational study including atopic dermatitis patients treated with dupilumab from January 2018 to July 2019. At baseline, patients underwent dermatological and ophthalmological assessments and at least one other joint visit during the 6-month follow-up. Appointments were scheduled at baseline, 1, 3, and 6 months for ophthalmologists. Ocular assessment included past ocular history and symptoms, Ocular Surface Disease Index (OSDI) score, slit lamp examination, tear film Break Up Time and Schirmer's test. Atopic dermatitis severity scores were assessed at baseline and 3 and 6 months by dermatologists
Life event-based marketing using AI
No full textInternational audienceThis paper investigates how firms can leverage innovative data sources and Artificial Intelligence (AI) for life event prediction to better manage the relationship with their customers. In this study, we leverage deep learning to explore the added value of incorporating textual customer-generated data in life event prediction models. Furthermore, we propose a new framework to calculate the profit of life event based-marketing campaigns. We empirically validate our research questions on a real-world dataset including 94,161 email messages of 21,898 customers in the financial services industry. First, we show that life events have a significant impact on both product possession and customer value. Second, we demonstrate that textual data significantly boosts the predictive performance of life event prediction models. Third, our framework to calculate profit for life event-based marketing campaigns shows that running such campaigns can lead to a substantial return on investment but requires a performant life event prediction model