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社会人専門学校生の学び直しに関する研究 ― 就学動機と学びの実態に関する調査結果から ―
Get PDF近年、生産性の向上、円滑な労働移動をもたらすものとして、社会人の学び直しへの期待が高まっている。しかし、就職に直結する学びの場である専門学校での学び直しに関する先行研究は少なく、学び直しを決断する要因や学びの状況は明らかになっていない。本研究は、専門学校で学ぶ社会人が、学び直しを決断する要因や、学びの実践が学習志向に与える影響を明らかにするものである。研究では、第一段階として医療系専門学校で学ぶ社会人学生にインタビュー調査を行い、第二段階で25校の専門学校の社会人学生を対象に質問紙調査を実施した。分析の結果、彼らの就学動機はキャリアチェンジであること、学び直しの決断にあたっては、精神的支援、経済的支援が影響を与えていること、クラスメイトとの関係が重要であること、専門性志向が高いほど学習継続意志が強いことなどが明らかになった。departmental bulletin pape
専門職大学における産学協働の仕事統合型教育はイノベータを生むことができるか、成果と課題～開志専門職大学情報学部の4 年間に渡る臨地実務実習を事例として～
Get PDF本論文では、急速に変化する社会のニーズに対応し、イノベーションを推進する人材を育成することの重要性を踏まえ、特定の業種を対象としない専門職大学における産学協働の仕事統合型教育の有効性を検証する。2020年4 月に開学した開志専門職大学の情報学部において、コロナ禍中に実施した情報学分野では日本初の試みである超長期の仕事統合型教育プログラム、臨地実務実習（企業実習）を事例として取り上げ、この教育プログラムが産業界の要請に適合した学生の問題解決能力、創造性、コミュニケーション能力等、イノベーションに必要な様々な能力の向上に寄与する可能性を明らかにする。また、さらに教育効果を高めるための課題と展望を述べる。departmental bulletin pape
Eects of Ultrasound Contrast Agents on Major Organs: A Study Using Small Animals
Get PDF論文(Article)Purpose: Concerns remain regarding the potential adverse effects of ultrasound contrast agents (UCA), particularly on local organs, following the identification of inflammation during the development of these agents. This study examined the expression of inflammatory genes in major organs during UCA administration and assessed their effect.
Subjects and Methods: Sprague-Dawley rats were divided into the UCA group (Sonazoid®, 0.015 mL/kg), which received subsequent ultrasound irradiation for 10 min, and control group, which received 0.015 mL/kg of saline instead of UCA. Major organs (heart, lungs, liver, and kidneys) were excised, and the expression of monocyte chemoattractant protein-1 (MCP-1), interleukin (IL)-6, IL-10, and tumor necrosis factor-alpha (TNF-α) was evaluated.
Results and Discussion: Significantly higher levels of expression of MCP-1, IL-6, and IL-10 were observed in all organs within the UCA-treated group than in the control group, with TNF-α significantly elevated in the liver and lungs. These findings suggest that UCA administration triggers local inflammation in organs, specifically in the liver and lungs. UCA microbubble accumulation within capillaries may induce inflammation via vascular endothelial injury.
Conclusions: This study provides novel insights into the adverse effects of UCA administration on major organ localization, confirming increased inflammatory gene expression induced by UCA in major organs. Notably, the liver and lungs demonstrate more pronouncedeeffects.目的：超音波造影剤（Ultrasound Contrast Agents: UCA）は，開発時に炎症が確認されているなど，UCA投与の潜在的な有害作用，特に臓器局所への有害作用に関する懸念が残っている．本研究では，UCA投与における炎症性遺伝子の発現に焦点を当て，主要臓器に及ぼす影響を評価した．
対象と方法：Sprague-Dawley ラットを用い，UCA投与群とControl 群に分けた．UCA投与（Sonazoid®，0.015 mL/kg）後に10分間超音波照射した．Control 群にはUCA投与の代わりに，生理食塩水を0.015 mL/kg投与した．その後，主要臓器（心臓・肺・肝臓・腎臓）を摘出し，MCP-1, IL-6, IL-10, TNF-αの遺伝子発現を評価した．
結果と考察：UCA投与群では，Control 群と比較してすべての臓器でMCP-1, IL-6, IL-10が有意に高値を示した．TNF-αは肝臓と肺で有意な高値を示した．この結果から，UCA投与により臓器局所での炎症が惹起され，特に肝臓および肺における傷害が顕著であることを明らかにした．毛細血管内でUCAのマイクロバブルが滞留・集積し，血管内皮傷害などが要因で炎症を惹起している可能性がある．
結論：本研究は，UCA投与における主要臓器局所への弊害の新たな知見を提示した．UCA投与による炎症性遺伝子の発現は主要臓器局所で増加し，その傷害は特に肝臓および肺において顕著であることが確認された．journal articl
Serum IL–27 as a potential biomarker for pain in late–stage hip osteoarthritis
Get PDF論文(Article)Cytokines play important roles not only in immune, but also in pain control systems. Since mice lacking interleukin (IL)–27 displayed pain hypersensitivities, we investigated the role of IL–27 in pain due to hip osteoarthritis in this clinical study. Twenty–one female patients with hip osteoarthritis (a mean age of 65.4 years) were enrolled. The levels of serum IL–27 at admission for surgery were evaluated and compared with the score of painDETECT (PD) questionnaire based on self–assessment of neuropathic pain, as well as the pain numeric rating scale (NRS) completed by all patients. The serum IL–27 levels significantly correlated with the NRS pain scores (R=–0.467, P=0.033), but not with the PD scores. These results indicate that serum IL–27 may control pain in osteoarthritis. Since serum IL–27 levels were not significantly affected by the type of pain, nociceptive or neuropathic, serum IL–27 may be a potential biomarker for chronic pain due to locomotor disorders.journal articl
Single-legged landing behavior of high school basketball players with chronic ankle instability
Get PDF論文(Article)Objectives: Anterior cruciate ligament injury is one of the most serious ligamentous injuries. The purpose is to compare the impact of the ankle joint on the knee during landing between athletes with chronic instability and a control group (coper group) and to verify the effects of the kinetic chain from other joints.
Design: Prospective study.
Setting: High school basketball.
Participants: Participants were 62 female high school basketball players who had participated in team sports for >6 months.
Main outcome measures: Player joint angles, movements, and moments.
Results: The knee valgus moment was significantly higher in the chronic ankle instability group than in the coper group (20%–60% [p < 0.01]; 80%–100% [p < 0.05]) during landing motion. The knee valgus moment was also significantly higher during the change from the maximum knee joint flexion position to the maximum extension (p < 0.05). In addition, the landing motions of the chronic instability group may have utilized suboptimal compensatory motor strategy on the sagittal plane, depending heavily on the knee joint’s abduction moment.
Conclusions: Our findings indicate that the chronic ankle instability group uses a different landing strategy pattern than the coper group by changing the joint moment and joint angle during landing, which may increase the risk of anterior cruciate ligament injury.journal articl
Intramuscular and abdominal fat measured by computed tomography and mortality of hemodialysis patients
Get PDF新潟医療福祉大学Niigata University of Health and Welfare博士(保健学)application/pdfNephrology Dialysis Transplantation. 2023, 39(2), p. 286-296.甲第105号doctoral thesi
オープンデータの提供者と利用者を繋ぐ取組についての考察 ― 自治体によるラウンドテーブル、ハッカソン、標準オープンデータセットの取組事例を中心にして―
Get PDFオープンデータの整備は市民の参加と産学官民の協働による地域課題の解決や経済活性化に資するものと期待され、わが国でも2010年前後から取り組みがはじまった。しかし、オープンデータを提供する自治体側ではオープンデータの効果やニーズの不明確さ、業務量増加や人材・予算などのリソース不足等が問題となっている。一方で、オープンデータの利用者側では、求めるデータがオープンデータでない、検索の困難さ、データの品質や量のばらつき等利便性の問題があり、このような提供者と利用者の乖離の結果として整備や利活用が進んでいないのが課題である。本稿でオープンデータの提供者と利用者を繋ぐ近年の都道県の取組事例を調査した結果、データの仲介者が解決に重要な役割を担っていた。departmental bulletin pape
Optimal duration and timing of basic‑life‑support‑only intervention for patients with out‑of‑hospital cardiac arrest
Get PDFapplication/pdfTo elucidate the relationship between the interval from cardiopulmonary resuscitation initiation to return of spontaneous circulation (ROSC) and neurologically favourable 1-month survival in order to determine the appropriate duration of basic life support (BLS) without advanced interventions. This population-based cohort study included patients aged ≥ 18 years with 9132 out-of-hospital cardiac arrest of presumed cardiac origin who were bystander-witnessed and had achieved ROSC between 2018 and 2020. Patients were classified into two groups based on the resuscitation methods as the “BLS-only” and the “BLS with administered epinephrine (BLS-AE)” groups. Receiver operating characteristic (ROC) curve analysis indicated that administering BLS for 9 min yielded the best neurologically outcome for patients with a shockable rhythm [sensitivity, 0.42; specificity, 0.27; area under the ROC curve (AUC), 0.60] in the BLS-only group. Contrastingly, for patients with a nonshockable rhythm, performing BLS for 6 min yielded the best neurologically outcome (sensitivity, 0.65; specificity, 0.43; AUC, 0.63). After propensity score matching, multivariate analysis revealed that BLS-only resuscitation [6.44 (5.34–7.77)] was associated with neurologically favourable 1-month survival. This retrospective study revealed that BLS-only intervention had a significant impact in the initial minutes following CPR initiation. Nevertheless, its effectiveness markedly declined thereafter. The optimal duration for effective BLS-only intervention varied depending on the patient’s initial rhythm. Consequently, advanced interventions should be administered within the first few minutes to counteract the diminishing effectiveness of BLS-only intervention.journal articl
身体状況と健康食品利用 attitude（認識と行動）との関連分析
Get PDF新潟医療福祉大学Niigata University of Health and Welfare博士(保健学)application/pdf新潟医療福祉会誌. 2023, 22(3), p. 54-70.甲第108号doctoral thesi