ARUd’A (Università “G. d’Annunzio CHIETI -PESCARA)
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Il terzo argomento: il graphic novel serbo tra Oriente e Occidente
No full textIl presente lavoro si dedica all’analisi di Treći argument (Il
terzo argomento, 1995), graphic novel ricavato dall’opera
di Milorad Pavić (1929-2009) e ritenuto dalla critica il
migliore adattamento grafico di un testo della letteratura
serba
The Role of Lifestyle Intervention in Female Fertility: A Modifiable Factor for Preconception Health
Full text linkInfertility is a growing global phenomenon affecting millions of individuals and is characterized by multifactorial causes, including both lifestyle and environmental factors. These include smoking, chronic exposure to environmental pollutants, stress, excessive caffeine or alcohol intake, drug use, improper eating habits and physical inactivity. The potential to modify these behaviors has gained increasing interest due to its impact on reproductive health and its role in mitigating infertility. Preconception counseling has also emerged as a fundamental strategy, providing education and risk assessments to improve pregnancy outcomes. Among lifestyle factors, nutrition, body composition and physical activity significantly influence female fertility, emphasizing the strong connection between metabolism and reproductive function. Supplementation with anti-inflammatory nutrients, such as omega-3 polyunsaturated fatty acids (n-3 PUFAs), a key component of the Mediterranean diet, may offer benefits for female fertility, partially through the modulation of gene expression in reproductive tissues. However, the specific mechanisms linking diet and fertility remain unclear. The primary objective of this review is to explore how the modification of selected lifestyle factors, with particular reference to dietary habits, may positively influence the female reproductive system and improve fertility and pregnancy-related outcomes
Europa – wohin soll es gehen? Jaspers bei den Rencontres Internationales de Genève (1946)
No full textComparison of the Core Training and Mobility Training Effects on Basketball Athletic Performance in Young Players: A Comparative Experimental Study
No full textThis study compared the effects of core (CTG) or mobility training (MTG) on basketball-specific skills in youth players, focusing on dynamic balance. Both training modalities have a recognized role in enhancing performance, but few studies have examined their impact on this population. Thirty-one young (age 14.71 ± 2.27 years) males were assigned to an 8-week CTG or MTG. Overhead Squat, Y-Balance Test, Agility T-Test, Sit-and-Reach, Functional Hop Tests, and the Balance Error Scoring System were assessed before (pre) and after (post) the intervention for both dominant (D) and non-dominant (ND) limbs. Both groups improved the postero-lateral direction of the Y-Balance Test for the D (CTG, MD [95% CIs] = −8.108 [−15.620, −0.595], p = 0.035; MTG, MD [95% CIs] = −15.234 [−23.512, −6.956], p = 0.024) and ND (CTG, MD [95% CIs] = −9.110 [−16.150, −2.070], p = 0.013; MTG MD [95% CIs] = −13.899 [−21.657, −6.141], p = 0.001) limb and the medial reach for D (CTG, MD [95% CIs] = −17.279 [−26.364, −8.194], p = 0.001; MTG, MD [95% CIs] = −22.050 [−32.061, −12.039], p = 0.03) and ND (CTG, MD [95% CIs] = −9.309 [−17.093, −1.526], p = 0.021; MTG, MD [95% CIs] = −13.614 [−22.190, −5.037], p = 0.003), the Overhead Squat Test (CTG, MD [95% CIs] = −3.059 [−3.797, −2.321], p = 0.001; MTG, MD [95% CIs] = −3.643 [−4.456, −2.830], p = 0.001), and Agility T-Test (CTG, MD [95% CIs] = 0.572 [0.072, 1.073], p = 0.026; MTG, MD [95% CIs] = 0.696 [0.145, 1.248], p = 0.024) skills. Only CTG showed a significant improvement (MD [95% CIs] = −8.294 [−16.162, −0.426], p = 0.04) in single-leg hop performance for the ND limb. No significant improvements were observed in static balance or flexibility. No time × group effect was found. Both interventions improved key basketball-specific motor abilities and could be added to the basketball training session without adverse effect
Brillouin spectroscopy of natural and chemically complex volcanic glasses: The role of divalent cations
No full textThis work investigates using Brillouin light scattering (BLS) spectroscopy the relationship between chemistry and longitudinal (or pressure) sound-wave propagation on a large dataset of alkaline to sub-alkaline silicate glasses. Results show that the frequency fB of the Brillouin peak decreases with the silica content and the Silica vs. Calcia - Ferrous oxide - Magnesia (SCFM) parameter, while it increases with the degree of polymerization expressed by the ratio of nonbridging oxygens to tetrahedral cations (NBO/T). It is possible to infer that the values of both fB and the real part of the longitudinal elastic modulus M' are tightly related to the content of divalent cations (M2+) participating in the silicate network. Our findings suggest that alkaline earth metals and Fe2+ linearly speed up the longitudinal acoustic waves in silicate glasses. This might open a new window on the possibility of using the BLS technique for rapid and accurate determinations of physical and chemical properties of natural glasses present on Earth and other planetary bodies
A Narrative Review: Syndecans in Aortic Aneurysm Pathogenesis and Course—Biomarkers and Targets?
No full textThe maintenance of the integrity of the entire endothelium, glycocalyx included, and, therefore, of tissue aorta’s homeostasis, depends on the expressions of several molecular pathways and their interactions, such as syndecan molecules. Alterations in syndecans, i.e., quantitative alterations or linking to their shedding, contributes to invoking endothelium dysfunction, which causes damage to the vessel wall due to the increased production of growth-stimulating and pro-inflammatory gene products. Inflammatory processes negatively affect the integrity of the endothelial glycocalyx, a dynamic layer of the luminal portion of endothelial cells composed of proteoglycans, glycoproteins, and glycosaminoglycans, i.e., syndecans. In turn, structural alterations in the endothelial glycocalyx influence the coagulative state, increasing pro-thrombotic processes. The family of syndecans constitutes a major component of glycocalyx or, more accurately, the major source of cell surface heparan sulfate. It encompasses four components: syndecan-1, syndecan-2, and syndecan-4 (with syndecan-3 only expressed in neural tissue), which have a fundamental role in regulating the events of acute and chronic aorta damage subsequently correlated with the formation of aneurysms. As such, the aim of our review is to highlight the current knowledge on the roles of syndecans and to analyze their relationship with the pathological processes of the aortic wall based on the most recent literature
Gender-based survival analysis in Nasal-Sinus Cancer: a resampling approach using a registry data
No full textBackground Nasal-Sinus Cancers (NSCs) develop in the nasal cavities or paranasal sinuses and account for approximately 1% of all malignant neoplasms. Survival in NSCs varies by several factors, including gender. However, small sample sizes in tumor registries may hinder the detection of significant survival differences. This study aims to investigate gender-based survival disparities in NSCs using resampling techniques to overcome such limitations and provide robust survival estimates. Methods We analyzed data from a tumor registry including NSCs cases diagnosed between 2016 and 2020. Due to limited cases (35 subjects), resampling was used to create two equal groups of 1,000 male and 1,000 female patients. Kaplan-Meier curves were generated by gender, and survival differences were tested using the log-rank test. The analyses were performed in R. Results Kaplan-Meier survival curves revealed clear differences between genders. The log-rank test showed a significant difference (p < 0.001), with males having a lower survival probability. Median survival was 48.3 months for females and 36.7 months for males. At 12 months, survival probability was 85% for females and 75% for males; at 24 months, 65% and 55%, respectively, confirming a consistent gender-based survival gap. Conclusions This analysis shows marked gender disparities in NSCs survival. Resampling allowed for a more stable estimation despite small initial samples. These findings suggest gender is a relevant prognostic factor and should be considered in clinical decisions. Further research should explore the causes behind these disparities, while health policies and treatment strategies must be tailored to address them. Key messages • Women with nasal-sinus cancer show significantly better survival than men: 48.3 vs 36.7 months (p < 0.001). • Resampling revealed gender survival disparities in NSCs, highlighting the need for gender-informed treatment strategies
