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HUMAN IMMUNODEFICIENCY VIRUS-ASSOCIATED CHANGES IN GERMINAL CENTERS OF LYMPH NODES AND RELEVANCE TO IMPAIRED B-CELL FUNCTION
No full textNON
CONGRESS REPORT: LYMPHOLOGICA "88, OCTOBER 14-16, 1988
No full textCONGRESS REPORT: LYMPHOLOGICA "88, OCTOBER 14-16, 198
LYMPHOCYTE AND ERYTHROCYTE TURNOVER IN THORACIC DUCT LYMPH IN PATIENTS WITH SCHISTOSOMAL HEPATOSPLENOMEGALY AND PORTAL HYPERTENSION
No full textIn 60 patients with hepatosplenic schistosomiasis and portal hypertension and in 20 control subjects, the turnover of erythrocytes and lymphocytes circulating in thoracic duct lymph was compared. Despite slight anemia in most patients with schistosomiasis, there was a greatly accelerated extravascular splanchnic circulation rate of erythrocytes. Lymphocytes also circulated more rapidly, but in contrast to erythrocytes, the peripheral blood lymphocyte count was elevated in schistosomal patients. Although thoracic duct lymph flow was increased at all stages of schistosomiasis, it was less rapid in "ascitic" and "varix bleeders" and thus the extravascular circulation turnover of erythrocytes and lymphocytes appeared to decline with chronicity of disease. The more rapid lymphocyte and erythrocyte "turnover," however, was almost entirely due to increased formation of interstitial fluid (greater lymph flow) suggesting that a prime regulator of splanchnic cellular migration was "solvent drag." These findings may derive from deranged portal microvascular dynamics (e.g., increased microvascular pressure, collagen deposition in Disse's space, capillarization of hepatic sinusoids, presinusoidal obstruction) as well as generalized host immunoresponsiveness to schistosomal infection
EPILOGUE: ARE LYMPHATICS DIFFERENT FROM BLOOD VESSELS
No full textEPILOGUE: ARE LYMPHATICS DIFFERENT FROM BLOOD VESSEL
LYMPHOSCINTIGRAPHIC FINDINGS THAT PREDICT FAVORABLE OUTCOME AFTER LYMPHATICOVENOUS ANASTOMOSIS
No full textRadionuclide lymphoscintigraphy is animaging technique used to radiologicallyevaluate the lymphatic system which can beutilized to evaluate signs of lymphaticobstruction that could be indication forlymphaticovenous anastomosis (LVA)operations. Our objective was to investigateand identify the radiographic signs inlymphoscinigraphy that predict favorableoutcome after LVA. We retrospectivelyreviewed the medical charts of 80 patientswith upper or lower-limb lymphedema whounderwent initial lymphoscintigraphy beforeLVA during the 2011 to 2014 study period toevaluate statistical association betweenlymphoscintigraphic findings and the clinicalresult after LVA. Following LVA, clinicalimprovement was observed in 50 patients (48female and 2 male) with no clinical improvementevident in the remaining 1 male and 29females. Dilated lymph vessels and dermalbackflow were identified as the abnormalfinding in lymphoscintigraphy that weresignificantly correlated with improved clinicalresult after LVA. Our conclusion is thatradionuclide lymphoscintigraphy prior to LVAis helpful in identifying patients for whomLVA is of benefit. Based on our findings,presence of dilated lymph vessels and presenceof dermal backflow are significantly correlatedwith improved clinical result after LVA
EDITORIAL: "THERE IS STILL SO MUCH TO BE DONE"
No full textEDITORIAL"THERE IS STILL SO MUCH TO BE DONE
THERMAL INJURY AND INDUCED THERMOTOLERANCE IN RAT LYMPH NODES
No full textImmersion of the rat's hind limb in water at 45°or 46°C for one hour caused a severe burn of the extremity,including the popliteal lymph node. Pretreatmentone day in advance at 45° C for 15 minutes or43° C for one hour prevented most of the damage tolymph node and other tissues. The production ofboth thermal necrosis and thermotolerance weredirect effects of heat on the lymph node. Thedistribution of necrosis in the lymph node (greatest inthe subcapsular region and least in the medulla)probably relates to thermal gradients and not to themicrostructure of the nodes, except perhaps forrelative resistance of the medulla