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    IN MEMORIAM

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    PROF. DR. ERMINIO CARIATI“Italian Pioneer of Modern Lymphology and Lymphatic Surgery”February 28, 1934 - July 20, 201

    CYP26B1 AND ITS IMPLICATIONS IN LYMPHANGIOGENESIS: LITERATURE REVIEW AND STUDY OF RARE VARIANTS IN TWO FAMILIES

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    CYP26B1 is a member of the cytochrome P450 family and is responsible for the breakdown of retinoic acid forwhich appropriate levels are important for normal development of the cardiovascular and lymphatic systems. In a cohort of 235 patients with lymphatic malformations, we performed genetic testing for the CYP26B1 gene. These probands had previously tested negative for known lymphedema genes. We identified two heterozygous missense CYP26B1 variants in two patients. Our bioinformatic study suggested that alterations caused by these variants have no major effect on the overall stability of CYP26B1 protein structure. Balanced levels of retinoic acid maintained by CYP26B1 are crucial for the lymphatic system. We identified that CYP26B1 could be involved in predisposition for lymphedema. We propose that CYP26B1 be further explored as a new candidate gene for genetic testing of lymphedema patients

    Overriding Democracy: American Intervention in Yeltsin’s 1996 Reelection Campaign

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    Still in the recent past, the 1996 Russian presidential election has not received sufficient historical attention for an event of its magnitude. Although there has always been evidence that the United States supported Boris Yeltsin’s reelection campaign, additional documentation regarding the Clinton administration’s direct interference to that end has since surfaced. This article aims to tell the story of that intervention and assess the impact it had on Yeltsin’s unexpected 1996 electoral comeback. I will outline the strategic incentives that pushed the administration toward pro-Yeltsin policies and stances in post-Cold War Russia, including the threat that Yeltsin’s strongest opponent posed to US interests in the region. After analyzing recently declassified Yeltsin-Clinton meeting transcripts, I will argue that the US manipulated international institutions and democracy promotion to help Yeltsin win reelection. Finally, I will compare this case of electoral intervention to others in history and discuss the legacy of it in the context of US-Russia relations since 1996

    Lesotho's white gold: the political ecology of temporality and the economy of anticipation in resource extraction and large dam infrastructural projects

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    The construction phases of large dam and infrastructural projects often extend over long periods of time, creating social, environmental, cultural, political, and economic consequences in the proximate communities and landscapes. The temporality of the phases of the project – from planning to construction to post-construction – reveal more layered and wide-ranging consequences from the social and environmental changes that result, sharpened by greater attention to how these changes unfold across multiple timescales and sites of the project. Using the case study of the Lesotho Highlands Water Project (LHWP), I draw on a political ecology approach that uses longitudinal data, including interviews, document analysis, and ethnographic fieldwork conducted in Lesotho since 1997, to illustrate how active project narratives draw from and promulgate an affective economy of anticipation in ways that aim to both sustain the hope of people affected by the project and contain their criticism of the project amidst a continued investment by the state in the expansion of the LHWP. As people directly affected experience disjunctures between the promises and the realities of the project over time, subsequent phases of the project are simultaneously renewed and recast through a logic of improvement that emphasizes changes in the implementation of the project while continuing to invest in the future imaginary of development that requires going forward with project plans. A logic of continuity and improvement structures this continued commitment to the capital intensive LHWP through the strategic mobilization of phases that scaffold both the material and physical dimensions of the project, but also the affective and anticipatory hopes of prosperity that the project represents. In this case, it also reveals how project authorities weave these dimensions – the material and the aspirational – into specific planned changes and improvements to address previous and ongoing concerns as projects progress over time. This longitudinal approach demonstrates the importance of temporal and affective dimensions to our understanding of the complex, multi-faceted consequences of resource extractive mega-dam projects such as the LHWP, particularly as they further rationalize the resource extractive approach to economic development in the region.Keywords: development, dams, infrastructure, political ecology, temporality, affect, resource extraction, economy of anticipation, displacement, construction, Lesotho, Southern Afric

    Entangled alternatives: political-economic conditions constructing farmer training programs as solutions to the farming crisis

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    This article contributes to debates about the potential of alternative food networks and their contradictions using sustainability-oriented farmer training programs as a case study. I provide an empirical account of the political-economic structures at play in the construction of farmer trainings as a solution to the farming crisis, as well as the possibilities and tensions herein. I argue that that the main rationale framing the farming problem in the public-institutional discourse – namely the apolitical production of a scarcity of farmers – and its discursive usage in popular and institutional circles directs the solution towards the urgent production of more farmers who will farm sustainably and independently of the current structural conditions in which farming is embedded. On the ground, this apolitical ecology is sustained by philanthropism and consumption elitism. In addition, the making of FTPs as an intervention to solve the farming crisis is determined by neoliberal governance structures that promote the devolution of power into the NGO sector and responsibilization of individuals. I finally call for a broader and non-binary vision to alternatives, in which political ecology perspectives bring relevant tools and insights. The case of FTPs throws light into the particular governmentalities, forms of governing at-a-distance, and whiteness associated with sustainable farming and agriculture, and the way society thinks of it.Keywords: farmer training programs, emergent farmers, sustainable agriculture, alternatives, alternative food networks, NGOization of farming, power, privilege, Californi

    REDD+ policy translation and storylines in Laos

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    This article examines the (re)production of discourses and storylines in the process of policy translation of Reducing Emissions from Deforestation and Forest Degradation (REDD+) in Laos. Applying the concepts of policy discourses and policy translation, we first identify the prominent storylines at the various governance levels in Laos. Second, we compare and contrast these storylines with the global REDD+ discourses. Further, we discuss how different actors' capacities and political agendas shape REDD+ storylines at different levels of governance. We find that national and sub-national storylines portray REDD+ mainly as a tool for supporting Laos' forestry strategy and sustainable forest management; for capacity-building and donor funding; and for village forest management and education of villagers. At the village level, many see REDD+ as a project for various political elites and external actors to control forests and cheat villagers. We conclude that, while globally there is increasing attention to civic-environmentalism in REDD+, neoliberalist and techno-managerial discourses still dominate. At the village level, however, civic-environmentalist ideas, such as social safeguards, benefit sharing, and equity largely disappear and two opposing discourses emerge representing anti-civic ideas and REDD+ resentment.  Furthermore, while techno-managerial ideas permeate all levels in Laos, neoliberalist ideas in terms of carbon trading are almost absent. During policy translation, REDD+ thus transforms into "just another" top-down development project. This serves the interest of Laos's techno-managerial elite well, but has little positive prospect for local people and forests. In this perspective, the lack of alternative discourse-coalitions promoting non-carbon benefits, social safeguards, and equity is striking.Key Words: REDD+, Laos, policy translation, environmental discourses, neoliberalism, civic environmentalism

    Political ecology and decolonial research: co-production with the Iñupiat in Utqiaġvik

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    Environmental social science research designs have shifted over the past several decades to include an increased commitment to multi-, inter-, and transdisciplinary team-based work that have had dual but complementary foci. These address power and equity in the substantive aspects of research, and also to adopt more engaged forms of practice, including decolonial approaches. The fields of political ecology, human geography, and environmental anthropology have been especially open to converge with indigenous scholarship, particularly decolonial and settler colonial theories and research designs, within dominant human-environmental social science paradigms. Scholars at the forefront of this dialogue highlight the ontological (ways of knowing), epistemological (how we know), and institutional (institutions of higher education) transformations that need to occur in order for this to take place. In this article we contribute to this literature in two ways. First, we highlight the synergies between political ecology and decolonial scholarship, particularly focusing on the power dynamics in research programs and historical legacies of human-environmental relationships, including those of researchers. Second, we explore how decolonial research pushes political ecologists and other environmental social scientists to not only consider adopting international and local standards of working with, by and for Indigenous Peoples within research programs but how this work ultimately extends to research and education within their home institutions and organizations. Through integrating decolonized research practices in the environmental social sciences, we argue that synthesizing multiple knowledge practices and transforming institutional structures will enhance team-based environmental social science work to improve collaboration with Indigenous scientists, subsistence practitioners, agency representatives, and sovereign members of Indigenous communities.Keywords: Alaska; collaboration; co-production; decolonial; Indigenous Knowledges; Iñupiaq People

    Selling women the green dream: the paradox of feminism and sustainability in fashion marketing

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    This article explores the paradox of corporations using social and environmental justice concerns to market products that are themselves made in conditions of environmental and social injustice, most often in the Global South. The effects of the fashion industry on people is two-pronged: 1) the unsafe and exploitative conditions under which many garment workers operate, and 2) the severe and harmful water and air pollution caused by fashion industry factories. There are thus contradictions inherent in the manner in which corporations, through their marketing, seek to foster feminism and environmentalism, whilst sourcing their garments from factories that operate in problematic ways. Using case studies of advertising campaigns from three Swedish companies, HM, Monki and Gina Tricot, we conducted a discourse analysis to understand the messages to consumers as well as the image of the company that is portrayed. Through our political ecology analysis, we suggest that the promotion of feminism and environmentalism is not consistently applied by companies in their own practices and could at worst be labeled green and 'fem washing.' These approaches can also be deeply problematic when they lead to the exotification of others, and cultural appropriation. We further find that the marketing strategies in fashion serve not only to promote the sale of products but also have the effect of placing environmental responsibility onto individual consumers. Ultimately, fashion marketing serves to obfuscate ecologically unequal exchange and the true costs of fashion.Key words: gender, marketing, consumption, feminism, fashion, textiles, advertising, ecologically unequal exchange, sustainabilit

    Transformation is what you expect, models are what you get: REDD+ and models in conservation and development

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    Models increasingly pervade conservation and development practice – model policies, model countries, model regions, model states, model projects, model villages, model communities and so on. These are idealized, bounded, miniature entities that seek to demonstrate the efficacy of a more substantive policy, scheme or intervention. Although political ecologists and critical scholars have analyzed models in specific interventions, there has been relatively little reflection on the common logics central to models more generally. Drawing on critical conservation and development literature and in-depth case studies of REDD+ in Tanzania and Nigeria, we identify and elaborate three core model logics: 1) problematization of the field of intervention and valorization of microcosms within it; 2) isolation and bounding which seek to order complexity and etch microcosms in space and time; 3) enrolment of actors. Although ambitious and transformational in its claims and aspirations, REDD+ has thus far manifested as an extensive network of models across socio-political scales. We argue that idealized REDD+ models enable proponents to demonstrate and 'sell' REDD+ as a 'successful' intervention, thereby allowing the scheme to persist in policy circles in spite of its failures on the ground and its lack of viability at scale. We therefore argue that models  often become an end in themselves, paradoxically failing to herald the transformational intervention they were originally meant to epitomize.Keywords: Conservation, development, models, Nigeria, Tanzania, REDD

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