Hakkari Üniversitesi Akademik Veri Yönetim Sistemi
Not a member yet
6688 research outputs found
Sort by
Anticancer and probiotic activities of Lacticaseibacillus paracasei isolated from traditionally fermented pickles
No full textBackground: Probiotics are living organisms and play a pivotal role in the natural treatment of gastrointestinal disorders including diarrhea, constipation, lactose intolerance and some bowel cancers. Beneficial effects are mostly attributed to postbiotic metabolites produced by bacteria, and the unique biological characteristics may vary depending on their species and source. The present study focused on identifying unique Lacticaseibacillus paracasei strains with unique probiotic and anticancer effects originating from fermented pickles. Results: Bacterial strains isolated from naturally fermented pickles were identified by 16S rRNA sequence analysis. Their probiotic properties were determined in simulated gastrointestinal environments created by pancreatin and pepsin. In addition, their adhesion capacities on L-929, HT-29 and Caco-2 cell lines were tested and then the cytotoxic effects of postbiotic metabolites and bacterial extracts obtained from bacterial isolates on cell lines were tested to determine their anticancer activities. In the overall results, isolates were found to be acceptable probiotics and to have anticancer activity. Conclusion: In addition to the acceptable activities of all strains, by elucidating their interaction mechanisms and evaluating their probiotic, functional and antiproliferative effects under in vivo conditions, especially LP001 and LP002 could be true sources of probiotics with anticancer effects in food and healthcare fields. © 2025 Society of Chemical Industry
Spiritual Care Experiences of Nurses Caring for Gynecologic Cancer Patients in Türkiye: A Qualitative Research
No full textThe study aimed to examine the spiritual care experiences of nurses caring for gynecologic cancer patients. The study was conducted using a phenomenological design, one of the qualitative research methods. Nurses caring for gynecologic cancer patients were included in the study. In sample selection, the criterion sampling method, one of the purposeful sampling methods, was used, and the sample size was ten nurses. A semi-structured interview guide was used to collect the data. Content analysis was performed using the MAXQDA package program. The study was written based on the COREQ checklist. The nurses’ statements determined themes, sub-themes, and codes in line with the research findings. Accordingly, four themes were identified as “spiritual care practices,” “emotional effects of spiritual care,” “factors affecting spiritual care,” and “recommendations to improve spiritual care”. In line with the findings obtained, it is recommended that in-service training should be provided to nurses caring for gynecologic cancer patients to provide spiritual care at a professional level. Moreover, the excessive workload caused by working conditions should be reduced, and regulations and institutional policies should be established to increase the number of nurses
Determination of Antioxidant and Anticancer Activities and Exopolysaccharides of Metabolites Synthesized by Probiotic Levilactobacillus brevis Strains Newly Isolated from Breast Milk
No full text
Investigating the role of mindful awareness as an antecedent of university students’ cyber security behaviors
No full text
