Parkview Health Research Repository
Not a member yet
774 research outputs found
Sort by
Impact of rapid identification of gram negative blood cultures in a community hospital system
Get PDFPresentation given at Great Lakes Pharmacy Residency Conference 201
Research Ethics Town Hall Meeting
No full textGROUP \u2718: Proceedings of the 2018 ACM International Conference on Supporting Group Work
As technology and data access continue to evolve, research ethics in the areas of Human-Computer Interaction and social computing are becoming increasingly complex. Despite increasing interest among researchers, there is still a lack of consistent community norms around ethical gray areas. One charge of the SIGCHI ethics committee is to help develop these norms by facilitating open conversations with different stakeholders. This panel will be an opportunity to develop a collective understanding of diverse perspectives on ethics, and to gather input from the GROUP research community around the ethical challenges we face as researchers who study social and collaborative computing systems and those who use these systems
The double-edged sword: A mixed methods study of the interplay between bipolar disorder and technology use
Get PDFHuman behavior is increasingly reflected or acted out through technology. This is of particular salience when it comes to changes in behavior associated with serious mental illnesses including schizophrenia and bipolar disorder. Early detection is crucial for these conditions but presently very challenging to achieve. Potentially, characteristics of these conditions’ traits and symptoms, at both idiosyncratic and collective levels, may be detectable through technology use patterns. In bipolar disorder specifically, initial evidence associates changes in mood with changes in technology-mediated communication patterns. However much less is known about how people with bipolar disorder use technology more generally in their lives, how they view their technology use in relation to their illness, and, perhaps most crucially, the causal relationship (if any exists) between their technology use and their disease. To address these uncertainties, we conducted a survey of people with bipolar disorder (N=84). Our results indicate that technology use varies markedly with changes in mood and that technology use broadly may have potential as an early warning signal of mood episodes. We also find that technology for many of these participants is a double-edged sword: acting as both a culprit that can trigger or exacerbate symptoms as well as a support mechanism for recovery. These findings have implications for the design of both early warning systems and technologymediated interventions.
Highlights Participants report that technology both helps and hinders their health 2/3 participants with bipolar disorder report changes in technology use during mood episodes Content-free methods that preserve privacy have promise for relapse detection Causal relationship likely to exist although possibly not-unidirectiona
Gastric Gastrointestinal Stromal Tumors (GIST): a Case Series and Current State of the Art in the Workup and Treatment of This Rare Disease
No full textResearch Key Highlights • Gastrointestinal stromal tumors (GISTs) are uncommon intramural tumors of the GI tract. They are most often seen in the stomach and arise from the muscular layers of the visceral wall. • The clinical manifestations of GISTs vary depending on the tumor size and location, but are often asymptomatic. • Advances in endosonography (EUS) and immunohistochemical staining can distinguish these lesions from other intramural and GI tract tumors and are an essential part of the diagnostic and staging workup. • The advent of EUS-guided fine needle biopsy (FNB) allows for large core tissue acquisition. This has replaced FNA and allowed for histologic analysis of large specimens, increased IHC confirmation, and personalized medicine. • Treatment involves surgical, endoscopic or hybrid endoscopiclaparoscopic resection. Imatinib may be given, and lesions less than 2 cm may be observed. • The cases presented in this report represent pathology-confirmed GISTs diagnosed at a large volume, community, tertiary referral GI oncology program during July 2012 through May 2016. Follow-ups for each patient have discovered no recurrences to date
Status of oncologic specialties: global survey of physicians treating cancer
No full textBackground In the United States, medical oncologists play a central role in the management of systemic therapy for cancer patients. Medical oncology as a specialty is not as established in Japan and several other European nations according to recent surveys, and little is known about this specialty in developing nations. We aimed to identify global differences in the roles of physicians treating cancer; specifically, how the management of advanced disease differs among nations. Methods In March 2016, a self-administered internet survey was conducted with degreed physicians who prescribed systemic agents for adult cancer treatment within the past 5 years. Physicians were identified from the American Society of Clinical Oncology active member online directory. Results Among 3907 members in 55 nations, 376 (9.6%) responded to the survey. The 310 respondents who provided an answer to the recognition of medical oncology were dominated by male MDs that have practiced for more than 5 years at academic centers, and ~60% were medical oncologists. A majority of the respondents in all four regions reported that medical oncology was established in their corresponding nations. However, there are several outlying nations where oncologic specialties play a minimal role in the management of systemic therapy. Conclusion Despite general recognition of medical oncology, the role is not globally established as the primary point of care for delivery of systemic therapy. Nations lacking this specialty should be assisted by the international community to develop medical oncology
Methicillin-susceptible Staphylococcus aureus: Utilization of decolonization protocol and incidence of surgical site infections in orthopedic and cardiac bypass surgical patients
No full text2017 ASHP Midyear Clinical Meeting / Orlando, Florida / Poster #10-095
Poster Presentation
Objective:
Evaluate the utilization of a decolonization protocol in methicillin-susceptible Staphylococcus aureus (MSSA) colonized patients following pre-admission testing at Parkview Health and the incidence of methicillin-resistant Staphyloccous aureus (MRSA) and MSSA in orthopedic, spinal, and cardiac surgical site infections (SSIs
Evaluating prescribing patterns of long-acting injectable antipsychotics at a community health system
No full text2017 ASHP Midyear Clinical Meeting / Orlando, Florida / Poster 10-084
Poster Presentation
Objective: Describe prescribing patterns for long-acting injectable antipsychotics and identify knowledge gaps in prescribing within our health system
Do You Have Anything to Hide? Infidelity-Related Behaviors on Social Media Sites and Marital Satisfaction.
No full textSocial media provides one route to behaviors that may be potentially harmful to romantic relationships, such as communicating with alternative partners, which can sometimes create relationship conflict, breakups, or divorce. Limited empirical evidence exists concerning social media infidelity-related behaviors and marital relationships. This study examined whether married/cohabiting individuals are using social media sites to engage in online infidelity-related behaviors and to what extent this related to relationship satisfaction, ambivalence, and relational attachment characteristics as reported by 338 married/cohabiting individuals from 176 families. Only a small percentage of married/cohabiting couples reported engaging in social media infidelity-related behaviors; however, more engagement in infidelity-related behaviors on social media was significantly related to lower relationship satisfaction, higher relationship ambivalence, and greater attachment avoidance and anxiety in both women and men. Additionally, attachment anxiety and gender interacted with relationship satisfaction in predicting online infidelity-related behaviors when controlling for other variables. Implications are discussed.
Free Full Text through Lin
Intravenous Ferumoxytol in Pediatric Patients With Iron Deficiency Anemia
No full textBACKGROUND:
Iron deficiency anemia (IDA) is common in children. Limited data exist on the efficacy and safety of ferumoxytol in children. OBJECTIVE:
To assess the efficacy of 10 mg/kg dose given over 15-60 minutes in correcting IDA and report any adverse drug reactions (ADRs). METHODS:
We conducted a retrospective review of all patients who received ferumoxytol infusions for the management of IDA by the Pediatric Blood Management Program between October 2010 and March 2015. RESULTS:
A total of 110 infusions were given to 54 patients. Compared with baseline preinfusion hemoglobin (Hb; 9.2 ± 1.9 g/dL), a significant rise was seen at 1 week and 4 weeks postinfusion (11.5 ± 1.5 and 11.8 ± 1.7 g/dL, respectively, P \u3c 0.001). Also, a significant rise in serum ferritin at 1 week and 4 weeks postinfusion was seen (51 ± 71 vs 192 ± 148 and 89 ± 135 ng/mL, P \u3c 0.001 and \u3c0.035, respectively). Patients who concomitantly received erythropoietin had a significantly larger Hb rise from baseline than those who did not at 4 weeks (2.7 ± 2.2 vs 1.6 ± 1.1 g/dL, P \u3c 0.017). ADRs included pruritus (n = 1), urticaria (n = 1), and multisymptom episodes (n = 3) that included shortness of breath, chest tightness, back pain, and epigastric cramping that responded to therapy with IV diphenhydramine and methylprednisolone. CONCLUSION:
Ferumoxytol was effective in treating IDA in our small study. Slow infusion rate and close monitoring allowed early detection of the infrequent ADRs
Improved Survival for Rural Trauma Patients Transported by Helicopter to a Verified Trauma Center: A Propensity Score Analysis
No full textOBJECTIVES:
Recent studies using advanced statistical methods to control for confounders have demonstrated an association between helicopter transport (HT) versus ground ambulance transport (GT) in terms of improved survival for adult trauma patients. The aim of this study was to apply a methodologically vigorous approach to determine if HT is associated with a survival benefit for when trauma patients are transported to a verified trauma center in a rural setting. METHODS:
The ascertainment of trauma patients age ≥ 15 years (n = 469 cases) by HT and (n = 580 cases) by GT between 1999 and 2012 was restricted to the scene of injury in a rural area of 10 to 35 miles from the trauma center. The propensity score (PS) was determined using data including demographics, prehospital physiology, intubation, total prehospital time, and injury severity. The PS matching was performed with different calipers to select a higher percentage of matches of HT compared to GT patients. The outcome of interest was survival to discharge from hospital. Identical logistic regression analysis was done taking into account for each matched design to select an appropriate effect estimate and confidence interval (CI) controlling for initial vital signs in the emergency department, the need for urgent surgery, intensive care unit admission, and mechanical ventilation. RESULTS:
Unadjusted mortalities for HT compared to GT were 7.7 and 5.3%, respectively (p \u3e 0.05). The adjusted rates were 4.0% for HT and 7.6% for GT (p \u3c 0.05). In a PS well-matched data set, HT was associated with a 2.69-fold increase in odds of survival compared to GT patients (adjusted odds ratio = 2.69; 95% CI = 1.21-5.97). CONCLUSIONS:
In a rural setting, we demonstrated improved survival associated with HT compared to GT for scene transportation of adult trauma patients to a verified Level II trauma center using an advanced methodologic approach, which included adjustment for transport distance. The implication of survival benefit to rural population is discussed. We recommend larger studies with multiple trauma systems need to be repeated using similar study methodology to substantiate our findings