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Inverter Reliability in PV Systems : State-Space Modeling and Bayesian Analysis
Full text linkThesis (M.S.)--Michigan State University. Electrical and Computer Engineering - Master of Science, 2025The push for cleaner energy sources, coupled with declining costs, has facilitated the massive deployment of solar photovoltaic (PV) systems in electric grids worldwide. At the heart of any PV system is the inverter, a device responsible for converting DC power captured by solar cells into AC power suitable for grid use. In recent years, reliability concerns have emerged regarding inverters, with multiple reports identifying central and string inverters as the primary culprits in most forced outages in PV systems. Inverter failures significantly hinder energy production, potentially reducing it to zero. Thus, estimating the reliability of these devices is crucial for forecasting the long-term performance of PV systems.In this thesis, we develop a state-space reliability model to characterize the failure behavior of string inverters, using a limited and heterogeneous failure dataset from residential and commercial PV systems in the U.S. Despite the data constraints, the proposed model successfully captures both decreasing and increasing failure rate behaviors observed in the data. Additionally, we derive an exponential approximation of the model, enabling system-level reliability evaluation via Markov Reward Models (MRM). To address the uncertainty inherent in limited datasets, we adopt a Bayesian framework, which is better suited for uncertainty quantification under data scarcity. This approach allows us to compute credible intervals on expected energy production by propagating parameter uncertainty through the MRM. Our findings indicate that, although parameter uncertainty is non-negligible, its impact on expected long-term energy yield remains limited\u2014primarily due to the relatively fast replacement of inverters compared to their average time to failure.Lastly, since the failure rate is an important quantity for reliability optimization and risk assessment, we establish a method for detailed failure rate estimation, providing deeper insights into the failure process. Following this approach, without relying on any major assumptions, the model estimations confirm our assumptions of a bathtub-like failure rate behavior.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references
Exploring the Connection Between Principals' Growth Mindsets and Leadership Practices : A Theory of Planned Behavior Approach
Full text linkThesis (Ph.D.)--Michigan State University. K-12 Educational Administration - Doctor of Philosophy, 2025This dissertation aimed to bridge the theoretical gap between beliefs and behaviors in educational leadership, using two theories from social psychology: growth mindsets and the Theory of Planned Behavior (TPB). Using the belief that intelligence is malleable as a case, I explored various reasons why school principals who firmly believe that every human can develop may or may not use practices aligned with that belief\u2014such as supporting teacher learning.One body of research suggests that when leaders believe intelligence is malleable, or when they have a growth mindset, they tend to engage in behaviors that are often more effective than those of leaders with a fixed mindset. These behaviors include providing more frequent support to teachers and offering regular feedback. However, other research indicates that this is not always the case with school principals. Using a Q-sort activity for in-depth interviews with 13 school principals in a Midwestern state, findings suggest that, despite possessing a growth mindset, school principals may not consistently engage in the expected leadership practices. To explore the reasons for this, I applied the Theory of Planned Behavior, a widely used framework in social psychology. TPB helped explain many factors influencing principals' decision-making but did not account for all observed behaviors. I employed both deductive and inductive approaches in my analysis. The deductive findings support the utility of TPB in analyzing principals' decision-making processes. However, the inductive findings reveal that other factors\u2014such as personal values and intrinsic motivation\u2014also play significant roles. Additionally, past experiences emerged as a crucial influence. This study indicates that a growth mindset alone is insufficient to ensure principals engage in practices that enhance student learning. Principals also need positive attitudes, strong and supportive subjective norms, and facilitating perceived behavioral controls to implement these practices. Notably, past successes can significantly influence decision-making, accounting for more than half of the reasoning when principals consider engaging in growth mindset-aligned leadership practices. The implications of this study are significant for growth mindset interventions, professional development for school principals, and policies that guide principals' leadership practices.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references
DI\u2022VERSE LITERACY : CULTURALLY RESPONSIVE RAP AND HIP HOP PHONEMIC AWARENESS INSTRUCTION CENTERING CHILDREN WHO SELF-IDENTIFY AS BLACK, BROWN, AND PEOPLE OF COLOR
No full textThesis (Ph.D.)--Michigan State University. Curriculum, Instruction, and Teacher Education - Doctor of Philosophy, 2025While the education field continues to engage in debates about literacy instruction, the science of reading, and systemic inequities in early literacy education are ongoing, young children who self-identify as Black, Brown, and People of Color enter primary grade classrooms across the United States and receive foundational literacy instruction that centers White Mainstream English and the experiences of the White dominant group of society due to systemic racism. As a result, many children engage in culturally and linguistically irrelevant literacy instruction that does not consider their identities, home languages, lived experiences, funds of knowledge, and various stages of literacy development, impeding their academic success in school. This mixed methods study, including quantitative and qualitative methodologies, constructs the Di\u2022VERSE Literacy framework to examine the influence of the innovative curriculum I designed on children who self-identify as Black, Brown, and People of Color foundational literacy development, particularly in phonemic awareness, and children\u2019s experiences engaging with the curriculum. This study draws upon multiple strength and asset-based frameworks, including culturally relevant pedagogy (Ladson-Billings, 1995, 2021), culturally and historically responsive pedagogy (Muhammad, 2020, 2023), culturally sustaining pedagogy (Paris, 2012), and Hip-Hop-Based Education (Hill, 2009) to create space during phonics instruction for children to access their identities, home languages, and lived experiences that are racially and culturally influenced to advance their literacy development in culturally just ways. Specifically, this case study highlights the perspectives and experiences of 13 first graders who self-identify as Black and Arab attending an urban intensive (Milner, 2012) public school in the US Midwest. As part of the study, I designed a three-week intervention including 15 lessons that aligned with multiple theoretical frameworks, education research, and state and national standards. The lessons were implemented by the children\u2019s teacher, who self-identified as White, and the children reflected on their experiences engaged with Di\u2022VERSE Literacy through induvial reflections including drawings and writing and during focus group interviews utilizing storytelling throughout the intervention. Additionally, children engaged in an individual pre- and post-assessment to demonstrate the influence of Di\u2022VERSE Literacy on their phonemic awareness development and beginning reading and writing development. While building upon and extending current educational research literature focusing on culturally responsive education, early literacy education, and Hip-Hop-Based Education, the findings highlight how young children who self-identify as Black and People of Color advanced their foundational literacy skills in culturally responsive ways. This study's findings also provide implications for teacher practice, school policy, and educational research to create opportunities for children who self-identify as Black, Brown, and People of Color to engage in culturally responsive foundational literacy instruction in US classrooms.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references
ESSAYS ON MANAGING MANUFACTURING AND SERVICE NETWORKS
Full text linkThesis (Ph.D.)--Michigan State University. Business Administration - Operations and Sourcing Management - Doctor of Philosophy, 2025This dissertation investigates how network structures and relational dynamics shape environmental and operational outcomes, with a focus on supply chain systems in manufacturing and service industries. The first two essays examine manufacturing supply networks, emphasizing the role of interfirm relationships in influencing environmental performance and transparency. The first essay explores the impact of downstream firms on the environmental efficiency of upstream suppliers across multi-tier supply chains. Drawing on FactSet Revere and Trucost data from six manufacturing sectors, the analysis reveals that downstream firms\u2019 environmental efficiency positively influences that of upstream partners \u2013 a relationship that intensifies under higher levels of financial dependence.The second essay examines the effect of buyer environmental disclosure on supplier disclosure, addressing concerns about potential supply chain leakage. Using data from FactSet Revere and Bloomberg environmental, social, and governance (ESG) covering the materials and pharmaceuticals sectors, the study finds no consistent evidence of a broad negative effect, suggesting that leakage may not be prevalent under voluntary disclosure regimes. However, the findings highlight key moderating dynamics. Structural social capital, reflected in shared network ties, plays a significant role: buyer\u2013supplier pairs with weaker structural overlap are more likely to exhibit negative effects, while stronger overlap mitigates this risk. Similarly, cultural similarity moderates outcomes \u2013 greater cultural dissimilarity correlates with negative effects on supplier disclosure, whereas culturally aligned pairs show no significant effect. The third essay turns to service networks, specifically examining how airline network configurations influence the management of operational disruptions. Using data from the U.S. Bureau of Transportation Statistics across seven major U.S. airlines, the analysis demonstrates that the network structure of an airline plays a critical role in managing delays, cancellations, and baggage handling issues. Together, these three essays contribute to a deeper theoretical and practical understanding of how varying network contexts -- across both manufacturing and service domains -- affect firms\u2019 environmental and operational performance.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references
DESIGN AND CHARACTERIZATION OF A CRYOGENIC CONTROL VALVE PLUG WITH EQUAL PERCENT CHARACTERISTICS
Full text linkThesis (M.S.)--Michigan State University. Chemical Engineering - Master of Science, 2025Automated valves are used in the process industry for precise control of process parameters (e.g. flow, pressure, temperature). For the proper process design of a system, it is crucial to ensure that these valves possess the appropriate flow coefficient to effectively regulate the fluid flow within these systems. Although automated control valves are widely available, very few domestic (USA) manufacturers offer automated control valves for cryogenic applications, especially helium systems where there is a need for control valves with precise flow control and low flow regulation (i.e., flow coefficient < 1.0). The present research aims to establish a comprehensive design methodology for developing an equal percent valve plug for use in a cryogenic control valve. The methodology adopts a holistic approach that integrates analytical, computational, and experimental techniques. An analytical model is developed to estimate the geometrical profile of an equal percent control valve plug for use in a commercially available cryogenic control valve. This model serves as the fundamental framework for estimating the valve flow characteristics. Predicted valve flow characteristics from the analytical model are be compared against results obtained from a computational fluid dynamics model (CFD). The implemented CFD model further enhances the understanding of the valve flow characteristics under various operating conditions through characterization of the internal flow across the valve plug profile. Results from both these theoretical models are validated against experimental measurements. Experimental results are obtained using a valve flow characterization test bench, which is designed and built to measure the flow and corresponding pressure drop across developed valve plug profile(s) under different operating conditions. The relationship between the valve lift and the flow coefficient characteristics for the developed profile(s) are captured from the measurements and compared against the theoretical predictions. The developed design methodology can assist cryogenic system designers and operators to generate control valve plug profiles based on a commercial control valve, as needed for efficient process control.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references
No Pain, A Lot to Gain : Exploring the Use of Virtual Reality to Increase Adherence to Dysphagia Therapy in Head and Neck Cancer Patients
Full text linkThesis (Ph.D.)--Michigan State University. Communicative Sciences and Disorders - Doctor of Philosophy, 2025Background: Radiation therapy (XRT) for head and neck cancer (HNC) can significantly impact a person\u2019s ability to swallow. Dysphagia exercises completed during XRT are known to benefit long term swallowing outcomes. However, adherence to therapy during XRT is low often because of pain from the oncological treatment. Complementary and integrative pain management techniques have been investigated with various cancer populations, including some focus on patients with head and neck cancer. Virtual reality (VR) is one such method, but it has not yet been studied with HNC patients as a pain mitigation approach to increase dysphagia therapy adherence. The goals of this dissertation are to: (1) determine the perceptions and experiences of speech-language pathologists (SLPs) on pain and pain management because they would principally be the ones doing such work, (2) assess the user experience (UX) in VR of adults without HNC, and (3) assess the feasibility and user experience of VR with HNC patients who are completing XRT. This foundational information is needed to inform future work assessing the efficacy of using VR for pain mitigation to optimize dysphagia therapy adherence. The feasibility and UX studies are vital because HNC patients in XRT often already experience negative side effects from their cancer treatment that might be exacerbated by effects from VR. Methods: The first study surveyed clinically practicing SLPs (N=207) regarding pain and pain management education, training, and implementation. Study two assessed adults without HNC (N=30) to establish a UX data set for adults without HNC. Following a single session VR, participants completed UX survey tools regarding usability, acceptability, and negative side effects. Study three assessed the UX of HNC patients (N=10) who participated in three sessions of VR (Pre-, Mid-, and Post-XRT). As part of this protocol, within session changes from pre- to post-VR in self-rated swallowing and general pain was tracked. In Studies 2 and 3, groups were block randomized into one of two VR conditions (active or passive VR) to allow exploration of the type of VR on UX. Results: SLPs reported limited education and training in pain and pain management despite caseloads frequently having individuals with pain that impacted evaluation and treatment, including therapeutic progress. There was strong support for the use of novel techniques for pain management. In study two, there were no differences in UX between active and passive VR experiences for adults without HNC. Patients with HNC in study three also showed no differences between active and passive virtual reality experiences. Negative side effects were minimal and remained consistent throughout the course of XRT. There were no differences in UX between individuals with and those without HNC in terms of usability and acceptability of VR, or presence of negative side effects. There were clinically meaningful reductions in both general and swallowing-related pain with use of virtual reality in the HNC patients. Conclusions: SLPs would benefit from increased opportunities in education and training on pain and pain management. They expressed willingness to use novel techniques, like VR, for this purpose. The user experience of VR in active and passive environments was positive for adults with and without HNC and both groups expressed a high level of willingness to adopt VR use. There were minimal negative side effects in both groups. Of importance was that clinically meaningful decreases in perceived pain (swallowing and general) occurred following VR sessions in the HNC patients. These results are promising and justify further studies beginning to look at the efficacy of VR as a pain mitigation tool for patients with HNC undergoing XRT.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references
FUEL COMPOSITION AND IGNITION SYSTEM VARIATION TO CONTROL COMBUSTION IN A RAPID COMPRESSION MACHINE
No full textThesis (Ph.D.)--Michigan State University. Mechanical Engineering - Doctor of Philosophy, 2025Aromatics have long been added to pump-grade gasoline to increase fuel octane number by increasing autoignition resistance. As octane number is expensive and impractical to determine, ignition delay time measurements are a promising way to understand autoignition resistance under modern engine operating conditions across equivalence ratios, with and without exhaust gas recirculation dilution. Therefore, ignition delay time measurements were used in Chapter 4 of this dissertation to understand the effect of six different aromatic additives on the autoignition resistance of a gasoline surrogate fuel between 700 K and 950 K at equivalence ratios relevant to current and next generation engines (\u3c6 = 0.6, 0.8, 1.0) and with exhaust gas recirculation dilution (0%, 15%, and 30%). The substituted phenol additives tested were p-cresol, 2,4-xylenol, 2,5-xylenol, 2,6-xylenol, 3,4-xylenol, and 3,5-xylenol, which all varied in methyl group quantity and location. From the results presented, it was found that the para-substituted methyl group was most important for increasing the ignition delay time of the base fuel, and that nearby methyl groups are also beneficial. In order of the greatest to least overall lengthening effect on the gasoline surrogate\u2019s ignition delay time, the additives are: 3,4-xylenol, 2,4-xylenol, p-cresol, 3,5-xylenol, 2,5-xylenol, 2,6-xylenol.As autoignition resistance is important for appropriate combustion timing to prevent misfires and extreme pressure rise rates, the next chapters of this dissertation aimed to characterize a turbulent jet ignition system to accommodate fuels with variable autoignition resistance. Turbulent jet ignition has long been studied with high octane number fuels to reduce engine emissions and extend the lean operating limit from spark ignition operation. This is possible because turbulent jet ignition works by increasing the rate of flame propagation through the main chamber by multiple ignition points, reducing the dependence on the mixture\u2019s laminar flame speed during main chamber charge consumption. By increasing the burning rate in the main chamber, the amount of time the end gas region is held at elevated temperatures and pressures is reduced, as is the quantity of unburned fuel and oxidizer. This, in turn, delays the occurrence and severity of the peak pressure rise rate due to autoignition of the unburned reactants. To test the promise of turbulent jet ignition with high cetane number fuels, Chapter 5 and Chapter 6 present simulations and experiments in a rapid compression machine to quantify the events during successful turbulent jet ignition and identify performance metrics. F-24 jet fuel/air mixtures were studied at low-temperature intake conditions, and three distinct events during each case of turbulent jet ignition were identified: peak pre-chamber ignition pressure, main chamber jet ignition, and autoignition. The amount of fuel burned before autoignition was also determined and the peak pressure rise rate from the turbulent jet ignition system was reduced by up to 41% from cases where combustion was initiated by autoignition.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references
RELATIONSHIPS AMONG IDENTITY DISCLOSURE, MENTAL HEALTH SYMPTOMS, AND PARTICIPATION IN CERVICAL CANCER SCREENING AMONG BISEXUAL ADULTS
Full text linkThesis (Ph.D.)--Michigan State University. Nursing - Doctor of Philosophy, 2025Screening reduces incidence of a late-stage cervical cancer diagnosis by 60%\u201390%. Yet, bisexual people are participate less than their heterosexual counterparts, putting them at higher risk for late-stage diagnosis. Guided by an adaptation of Quinn & Earnshaw\u2019s Concealable Stigmatized Identity \u2013 Outcomes Model (CSI-O), this dissertation aimed to identify and investigate relationships among key determinants of cervical cancer screening participation among bisexual adults eligible for screening. With a focus on bisexual adults, three Manuscripts served to answer 4 research questions: (1) What determinants of health are associated with cancer screening participation?; (2) What is the predictive relationship between identity disclosure and mental health symptoms?; (3) What is the predictive relationship between identity disclosure and cervical cancer screening participation?; and (4) What is the predictive relationship between mental health symptoms and cervical cancer screening participation? Manuscript 1 was a systematic literature review that identified how determinants of health relate to cancer screening participation among differing stigmatized sexual identities. Gaps identified within existing literature supported priority areas of study, including (1) cancer screening contexts; (2) stigmatized sexual or gender identity groups; and (3) determinants of health affecting screening participation. Priorities identified in this systematic review were applied to the CSI-O model to support the remaining chapters. Manuscript 2 applied a secondary analysis of a broader study and examined the relationships between gender identity disclosure and mental health symptoms among people assigned female at birth who identified as bisexual and transgender. Findings supported that lower identity disclosure was associated with poorer mental health, but the association of identity disclosure with mental health depended on the disclosure setting; people who disclosed in healthcare settings, but not at home, reported higher anxiety and depressive symptoms. Additionally, identity disclosure patterns provided a comprehensive understanding of the relationships between identity disclosure and mental health. Manuscript 3 used a descriptive cross-sectional study to examine how identity disclosure and mental health predict cervical cancer screening participation among bisexual adults. Broadening the findings from the secondary analysis (Manuscript 2), the sample included bisexual adults, either cisgender or transgender. Findings suggested that identity disclosure was associated with cervical cancer screening participation among bisexual people, but associations were dependent on how identity disclosure was measured, and the cervical cancer screening participation outcome considered. Identity disclosure pattern was significantly associated with cervical cancer screening participation, and individuals who disclosed identity at their last cervical cancer screening were more likely to be up-to-date. However, level of identity disclosure in an individual setting was not associated with any cervical cancer screening participation outcome. Compared to those who reported no fear of stigma in healthcare, those who reported having fear were significantly less intent to screen. Research: Key relationships were identified in the adapted CSI-O model: identity disclosure and mental health symptoms predict behavioral outcomes, and identity disclosure predicts mental health. Strong statistical methods were employed in this study, including multiple regression, which supported the predictive relationships outlined in the adapted CSI-O model; however, they do not confirm causality. Practice: Past difficulty receiving healthcare due to stigmatized gender identity was related to poor mental health, and fear of stigma in healthcare was related to lower intention to screen. To prevent negative outcomes, providers should maintain affirming care environments for bisexual people. Policy: To support unique care needs of stigmatized groups, creative solutions are needed to replace previously available government funding. At-home testing kits are available for cervical cancer self-screening, and should be more widely available to support increased participation for bisexual people. Conclusion: This dissertation is the first step towards understanding unique needs of bisexual people in cancer screening. Bisexual-specific factors for cervical cancer screening participation are identified, and findings provide a pathway toward individualized care for at-risk groups.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references
Stigma and Stuttering : A Health Communication Perspective
Full text linkThesis (M.A.)--Michigan State University. Communicative Sciences and Disorders - Master of Arts, 2025Globally, negative stigma and misconceptions of stuttering profoundly impact people who stutter, limiting their participation in daily life activities, and vocational, educational, and social opportunities (Boyle, 2018; Boyle et al., 2018; Boyle & Fearon, 2018; Briley et al., 2021a; Werle et al., 2021). Previous anti-stigma interventions have demonstrated moderate attitudinal improvement among the general population toward stuttering (Abdalla & St. Louis, 2014; Boyle et al., 2016; Flynn & St. Louis, 2011; Kuhn et al., 2015; Langevin & Prasad, 2012; St. Louis et al., 2018, 2020a; St. Louis & Flynn, 2018; Weidner et al., 2018). The current study examined previous anti-stigma interventions across various stigmatized conditions, populations, and settings and sought to identify facilitators and barriers associated with stigma reduction toward stuttering. Key components from previously successful interventions were used to guide the formation of a novel evidence-based intervention: a pre-recorded presentation given by a person who stutters designed for adults who are not communicative sciences and disorders students or graduates and do not stutter, which utilized contact and education approaches. Using the Public Opinion Survey of Human Attributes \u2013 Stuttering (POSHA-S) (St. Louis, 2022), a standardized assessment, participants\u2019 attitudes, reactions, and beliefs toward stuttering were measured using posttest only control group design and open-ended questions.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references
COMPARATIVE GENOMICS IN BREAST CANCER : INSIGHTS FROM MURINE MODELS TO HUMAN DISEASE MECHANISMS
Full text linkThesis (Ph.D.)--Michigan State University. Biochemistry and Molecular Biology - Doctor of Philosophy, 2025Breast cancer is the most diagnosed cancer in women in the United States and throughout the world. Current estimates have approximately 1 out of every 8 women will get breast cancer at some point in their lifetime, while 1 out of every 39 women will ultimately die from breast cancer in the United States. Breast cancer is a heterogeneous disease, with no two patients\u2019 breast cancers being exactly alike. The research and medical communities have spent a significant amount of effort to characterize and classify breast cancers into meaningful subtypes that represent different possible treatment modalities. Despite treatment advances in targeting specific breast cancer subtypes, we still lack effective treatment options for various subtypes of breast cancer and patients with advanced/metastatic breast cancer. A large domain of cancer research centers around attempting to mimic human breast cancer subtypes in mice to mechanistically study oncogenes and tumor suppressors in controlled environments. Identification of mouse models representative of human breast cancer subtypes would enable sensitive and specific therapeutic development targeting breast cancer subtypes while limiting systemic toxicity. One of the ways researchers classify breast cancers into meaningful categories is through intrinsic subtypes, where breast cancer subtypes are defined by differential expression of key genes known to be involved in oncogenic signaling pathways unique to each subtype. The differential expression of these genes often stems from acquired genomic alterations. I hypothesize that comparative genomics betweenhuman breast cancer subtypes and mouse models of breast cancer would allow identification of additional genomic oncogenic driver events, potentially establishing links between specific mouse models of breast cancer to human breast cancer subtypes. Follow up in vitro and in vivo mechanistic studies can then be used to validate computational findings to confirm putative oncogenic drivers. To this end, I analyzed the genomes of spontaneous primary mammary gland tumors from different mouse models of breast cancer, focusing on the MMTV-Cre E2F5 conditional knockout, MMTV-Myc, and MMTV-Neu mouse models. In summary, I found that MMTV-Cre driven E2F5 conditional knockout in the murine mammary gland resulted in highly heterogeneous genomic alterations, but most tumors independently developed amplification events centered on Wnt2, Met, Cav1, and Cav2, while also possessing the same highly impactful splice acceptor mutation in Fbxo15. The MMTV-Myc mouse model of breast cancer generates several distinct histological subtypes, from which I identified that the EMT histological subtype coalesces on heterogeneous activation of the Kras pathway through Kras activating mutations or Fgfr2 amplification, while the microacinar subtype develops co-occurring mutations in Kit and Rara and amplifications over chromosomes 11 and 15. Finally, I interrogated the previously discovered 17q21.33 amplicon centered over putative oncogenes COL1A1, CHAD, and PHB1 involved in metastasis in HER2+ breast cancer. I found increased breast cancer metastasis signatures and increased estrogen signaling but failed to identify the specific role each gene played in the metastatic cascade. These results underscore the potential impact of genomic sequencing in mouse models of breast cancer and their applicability to studying human breast cancer development and treatment.Description based on online resource. Title from PDF t.p. (Michigan State University Fedora Repository, viewed ).Includes bibliographical references