Repositorio Universidad Internacional Iberoamericana
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Optimal Sizing and Deployment of Renewable Energy Generators in Practical Transmission Network Using Grid-Oriented Multiobjective Harmony Search Algorithm for Loss Reduction and Voltage Profile Improvements
No full textThis paper presents grid-oriented multiobjective harmony search algorithm (GOMOHSA) to incorporate the multiple grid parameters for minimization of the active power loss, reactive power loss, and total voltage deviations (TVD) in a part of practical transmission network of Rajasthan Rajya Vidyut Prasaran Nigam Limited (RVPN) in southern parts of Rajasthan state of India. This is achieved by optimal deployment of optimally sized renewable energy (RE) generators using GOMOHSA. Performance indexes such as active power loss minimization index (APMLI), the reactive power loss minimization index (RPMLI), and the total voltage deviation improvement index (TVDII) are introduced to evaluate the health of the test network with different load scenarios. Performance of proposed GOMOHSA has been tested for five different operating scenarios of loads and RE generation. It is established that the proposed GOMOHSA finds the optimal deployment of optimally sized RE generators, and the investment cost of deployment of these RE generators can be recovered within a time period that is less than 5 years. Performance of GOMOHSA is superior compared to a conventional genetic algorithm (GA) in terms of performance indexes, RE generator capacity, payback period, and parameter sensitivity. Study is performed using MATLAB software for loading scenario of base year 2021 and projected year 2031
Breast Cancer Prediction Using Fine Needle Aspiration Features and Upsampling with Supervised Machine Learning
No full textBreast cancer is prevalent in women and the second leading cause of death. Conventional breast cancer detection methods require several laboratory tests and medical experts. Automated breast cancer detection is thus very important for timely treatment. This study explores the influence of various feature selection technique to increase the performance of machine learning methods for breast cancer detection. Experimental results shows that use of appropriate features tend to show highly accurate predictio
In Vivo Anti-Alzheimer and Antioxidant Properties of Avocado (Persea americana Mill.) Honey from Southern Spain
No full textThere is growing evidence that Alzheimer’s disease (AD) can be prevented by reducing risk factors involved in its pathophysiology. Food-derived bioactive molecules can help in the prevention and reduction of the progression of AD. Honey, a good source of antioxidants and bioactive molecules, has been tied to many health benefits, including those from neurological origin. Monofloral avocado honey (AH) has recently been characterized but its biomedical properties are still unknown. The aim of this study is to further its characterization, focusing on the phenolic profile. Moreover, its antioxidant capacity was assayed both in vitro and in vivo. Finally, a deep analysis on the pathophysiological features of AD such as oxidative stress, amyloid-β aggregation, and protein-tau-induced neurotoxicity were evaluated by using the experimental model C. elegans. AH exerted a high antioxidant capacity in vitro and in vivo. No toxicity was found in C. elegans at the dosages used. AH prevented ROS accumulation under AAPH-induced oxidative stress. Additionally, AH exerted a great anti-amyloidogenic capacity, which is relevant from the point of view of AD prevention. AH exacerbated the locomotive impairment in a C. elegans model of tauopathy, although the real contribution of AH remains unclear. The mechanisms under the observed effects might be attributed to an upregulation of daf-16 as well as to a strong ROS scavenging activity. These results increase the interest to study the biomedical applications of AH; however, more research is needed to deepen the mechanisms under the observed effect
Formulación de proyectos en Mypes: evidencia empírica de la ausencia de un modelo práctico
No full textEsta es una investigación que aborda la actividad de la formulación de proyectos de gestión organizacional (PGO) en micro y pequeñas empresas (Mypes), con un ejercicio investigativo de enfoque cuantitativo, correlacional y transversal, dentro de un estudio de caso, para probar la hipótesis que: A mayor cantidad de elementos teóricos utilice un microempresario en la formulación de sus proyectos, mayor desarrollo de los factores determinantes de supervivencia empresarial logra, proceso que permite determinar la existencia o no de un modelo adoptado a las particularidades operativas de este tipo empresarial, utilizando para ello un instrumento Ad hoc validado por juicio de expertos, en dos etapas (diseño y calibración), con CVC de 0.98, Fleiss de Kappa para constructo y objetividad de 0.95, con coeficiente de estabilidad temporal de Pearson de 0.95 y alfa de Cronbach de 0.81. El resultado indica que en el caso de la población objeto del estudio, no existe un modelo adaptado y usado mayoritariamente por las Mypes, además con un Rho de Spearman de 0.617 se evidencia una correlación fuerte entre las variables estudiadas, lo que permite aportar el concepto de incorporar los Rasgos Distintivos Operacionales (RDO) de las Mypes al desarrollo de teorías gerenciales adaptadas a sus realidades operativas para la formulación de PGO
Resilience Optimization of Post-Quantum Cryptography Key Encapsulation Algorithms
No full textRecent developments in quantum computing have shed light on the shortcomings of the conventional public cryptosystem. Even while Shor’s algorithm cannot yet be implemented on quantum computers, it indicates that asymmetric key encryption will not be practicable or secure in the near future. The National Institute of Standards and Technology (NIST) has started looking for a post-quantum encryption algorithm that is resistant to the development of future quantum computers as a response to this security concern. The current focus is on standardizing asymmetric cryptography that should be impenetrable by a quantum computer. This has become increasingly important in recent years. Currently, the process of standardizing asymmetric cryptography is coming very close to being finished. This study evaluated the performance of two post-quantum cryptography (PQC) algorithms, both of which were selected as NIST fourth-round finalists. The research assessed the key generation, encapsulation, and decapsulation operations, providing insights into their efficiency and suitability for real-world applications. Further research and standardization efforts are required to enable secure and efficient post-quantum encryption. When selecting appropriate post-quantum encryption algorithms for specific applications, factors such as security levels, performance requirements, key sizes, and platform compatibility should be taken into account. This paper provides helpful insight for post-quantum cryptography researchers and practitioners, assisting in the decision-making process for selecting appropriate algorithms to protect confidential data in the age of quantum computing
DrunkChain: Blockchain-Based IoT System for Preventing Drunk Driving-Related Traffic Accidents
No full textTraffic accidents present significant risks to human life, leading to a high number of fatalities and injuries. According to the World Health Organization’s 2022 worldwide status report on road safety, there were 27,582 deaths linked to traffic-related events, including 4448 fatalities at the collision scenes. Drunk driving is one of the leading causes contributing to the rising count of deadly accidents. Current methods to assess driver alcohol consumption are vulnerable to network risks, such as data corruption, identity theft, and man-in-the-middle attacks. In addition, these systems are subject to security restrictions that have been largely overlooked in earlier research focused on driver information. This study intends to develop a platform that combines the Internet of Things (IoT) with blockchain technology in order to address these concerns and improve the security of user data. In this work, we present a device- and blockchain-based dashboard solution for a centralized police monitoring account. The equipment is responsible for determining the driver’s impairment level by monitoring the driver’s blood alcohol concentration (BAC) and the stability of the vehicle. At predetermined times, integrated blockchain transactions are executed, transmitting data straight to the central police account. This eliminates the need for a central server, ensuring the immutability of data and the existence of blockchain transactions that are independent of any central authority. Our system delivers scalability, compatibility, and faster execution times by adopting this approach. Through comparative research, we have identified a significant increase in the need for security measures in relevant scenarios, highlighting the importance of our suggested model
Real Word Spelling Error Detection and Correction for Urdu Language
No full textNon-word and real-word errors are generally two types of spelling errors. Non-word errors are misspelled words that are nonexistent in the lexicon while real-word errors are misspelled words that exist in the lexicon but are used out of context in a sentence. Lexicon-based lookup approach is widely used for non-word errors but it is incapable of handling real-word errors as they require contextual information. Contrary to the English language, real-word error detection and correction for low-resourced languages like Urdu is an unexplored area. This paper presents a real-word spelling error detection and correction approach for the Urdu language. We develop an extensive lexicon of 593,738 words and use this lexicon to develop a dataset for real-word errors comprising 125562 sentences and 2,552,735 words. Based on the developed lexicon and dataset, we then develop a contextual spell checker that detects and corrects real-word errors. For the real-word error detection phase, word-gram features are used along with five machine learning classifiers, achieving a precision, recall, and F1-score of 0.84,0.79, and 0.81 respectively. We also test the proposed approach with a 40% error density. For real-word error correction, the Damerau-Levenshtein distance is used along with the n-gram model for further ranking of the suggested candidate words, achieving an accuracy of up to 83.67%
Betalains: The main bioactive compounds of Opuntia spp and their possible health benefits in the Mediterranean diet
No full textBetalains are water-soluble, nitrogen-containing vacuolar pigment and can be divided into two subclasses: the yellow – orange betaxanthins and the red – violet betacyanin. These pigments can be found mainly in Latin America, but also in some parts of Asia, Africa, Australia and in the Mediterranean area. In this work an overview related with the status of research about betalains extracted from Opuntia spp and the enforces made to evaluate their positive incidence in the human body is provided. Several studies enhance their anticancer, anti-inflammatory and antioxidant properties. They also exhibit antimicrobial and antidiabetic effect. Taking into account these properties, betalains seem to be a promising natural alternative as a colorant to replace the synthetic ones in the food additive industry. In addition, the use of Opuntia spp fruits as possible colorant sources in the Food Industry, may contribute positively to the sustainable development in semi-arid regions
Can alpha‐linolenic acid be a modulator of “cytokine storm,” oxidative stress and immune response in SARS‐CoV‐2 infection?
No full textAlpha-linolenic acid (ALA) is a long-chain polyunsaturated essential fatty acid of the Ω3 series found mainly in vegetables, especially in the fatty part of oilseeds, dried fruit, berries, and legumes. It is very popular for its preventive use in several diseases: It seems to reduce the risk of the onset or decrease some phenomena related to inflammation, oxidative stress, and conditions of dysregulation of the immune response. Recent studies have confirmed these unhealthy situations also in patients with severe coronavirus disease 2019 (COVID-19). Different findings (in vitro, in vivo, and clinical ones), summarized and analyzed in this review, have showed an important role of ALA in other various non-COVID physiological and pathological situations against “cytokines storm,” chemokines secretion, oxidative stress, and dysregulation of immune cells that are also involved in the infection of the 2019 novel coronavirus. According to the effects of ALA against all the aforementioned situations (also present in patients with a severe clinical picture of severe acute respiratory syndrome-(CoV-2) infection), there may be the biologic plausibility of a prophylactic effect of this compound against COVID-19 symptoms and fatality
Prevalence and genetic diversity of rotavirus in Bangladesh during pre-vaccination period, 1973-2023: a meta-analysis
No full textIntroduction: Rotavirus infection is a major cause of mortality among children under 5 years in Bangladesh. There is lack of integrated studies on rotavirus prevalence and genetic diversity during 1973 to 2023 in Bangladesh.
Methods: This meta-analysis was conducted to determine the prevalence, genotypic diversity and seasonal distribution of rotavirus during pre-vaccination period in Bangladesh. This study included published articles on rotavirus A, rotavirus B and rotavirus C. We used Medline, Scopus and Google Scholar for published articles. Selected literatures were published between 1973 to 2023.
Results: This study detected 12431 research articles published on rotavirus. Based on the inclusion criteria, 29 of 75 (30.2%) studies were selected. Molecular epidemiological data was taken from 29 articles, prevalence data from 29 articles, and clinical symptoms from 19 articles. The pooled prevalence of rotavirus was 30.1% (95% CI: 22%-45%, p = 0.005). Rotavirus G1 (27.1%, 2228 of 8219) was the most prevalent followed by G2 (21.09%, 1733 of 8219), G4 (11.58%, 952 of 8219), G9 (9.37%, 770 of 8219), G12 (8.48%, 697 of 8219), and G3 (2.79%, 229 of 8219), respectively. Genotype P[8] (40.6%, 2548 of 6274) was the most prevalent followed by P[4] (12.4%, 777 of 6274) and P[6] (6.4%, 400 of 6274), respectively. Rotavirus G1P[8] (19%) was the most frequent followed by G2P [4] (9.4%), G12P[8] (7.2%), and G9P[8], respectively. Rotavirus infection had higher odds of occurrence during December and February (aOR: 2.86, 95% CI: 2.43-3.6, p = 0.001).
Discussion: This is the first meta-analysis including all the studies on prevalence, molecular epidemiology, and genetic diversity of rotavirus from 1973 to 2023, pre-vaccination period in Bangladesh. This study will provide overall scenario of rotavirus genetic diversity and seasonality during pre-vaccination period and aids in policy making for rotavirus vaccination program in Bangladesh. This work will add valuable knowledge for vaccination against rotavirus and compare the data after starting vaccination in Bangladesh