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Validity, Reliability and Responsiveness of the Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (bety-Bq) in Knee Osteoarthritis
Yakut, Yavuz; Oksuz, Sevim; Unal, EdibePurposeThis study was planned to test whether the Cognitive Exercise Therapy Approach- Biopsychosocial Questionnaire (BETY-BQ) is an appropriate questionnaire in assessing the biopsychosocial status in KOA.MethodsFrequently used assessment tools, OA-specific scale The Western Ontario and McMaster Universities OA Index, the Hospital Anxiety and Depression Scale, and the Short Form-36 were utilized for the validity and responsiveness of BETY-BQ in individuals with KOA. The test-retest method, internal consistency analysis, and item analysis were used to test reliability. For the test-retest method, BETY-BQ was administered again to the same 30 individuals 1 week later. To assess the responsiveness of the BETY-BQ, individuals who underwent medical treatment were subjected to a second round of questionnaire administration after a 3-month interval.ResultsModerate to weak correlations between BETY-BQ and the other questionnaires ensued the divergent validity. According to the confirmatory factor analysis, all goodness-of-fit indices of BETY-BQ were acceptable (CMIN/df = 2.212; RMSEA = 0.080; SRMR = 0.08). Both Cronbach's alpha (0.900) and ICC value (0.941) showed that the BETY-BQ has excellent reliability in the KOA population. The Bland-Altman Plot showed high agreement as all differences between the first and second BETY-BQ were found between the 95% lower and upper limits. BETY-BQ demonstrated moderate responsiveness as the effect size and standardized mean response were 0.656 and 0.566, respectively.ConclusionA valid, reliable, responsive, multi-dimensional, and self-reported questionnaire for measuring biopsychosocial status in KOA was introduced to the use of healthcare professionals.Science Citation Index Expande
The Association of Exhaled Nitric Oxide Level With Respiratory Muscle Strength, Pulmonary Function, Exercise Capacity, Sleep Quality, Functional Status, and Health-Related Quality of Life in Patients With Pulmonary Arterial Hypertension
Scientific Research Projects Coordination Unit of Istanbul University-Cerrahpasa (Istanbul, Turkey) [TDK-2018-31147]This abstract is funded by: Scientific Research Projects Coordination Unit of Istanbul University-Cerrahpasa (Istanbul, Turkey) as project number TDK-2018-31147Science Citation Index Expanded - Conference Proceedings Citation Index - Scienc
Effectiveness of Postoperative Cephalosporins in Reducing Urinary Tract Infections and Other Parameters Following Transurethral Resection of the Prostate: a Systematic Review and Meta-Analysis
Ibrahim, Ismail/0000-0002-0805-8181[No Abstract Available]Science Citation Index Expande
Isolation of Rosmarinic Acid From Rosemary Extract Utilizing a Molecularly Imprinted Polymer
Molecularly imprinted polymers are polymeric materials engineered with specific templates capable of recognizing molecules selectively. Rosmarinic acid, an ester formed from caffeic acid and 3,4-dihydroxyphenyllactic acid and commonly occurring in plants, exhibits a broad spectrum of bioactive properties, including antioxidant, antiviral, analgesic, antibacterial, antimutagenic, antiallergic, anti-inflammatory, and neuroprotective effects. It is prominently present in rosemary (Rosmarinus officinalis) extracts, where it acts as the primary phenolic compound responsible for antioxidant activity. Advancements in the refining techniques for recovering and purifying rosmarinic acid from rosemary extracts have driven progress in molecularly imprinted solid-phase extraction methods. Remarkably, the molecularly imprinted solid-phase extraction approach utilizing the 1:4:16 caffeic acid-imprinted polymer exhibited outstanding selectivity for rosmarinic acid in authentic rosemary samples, achieving a purity level of 84% ± 2.96%. This research marks a significant advancement in the literature, being the first to demonstrate the effective purification of rosmarinic acid using caffeic acid-imprinted polymers. These findings underscore the efficacy of the MIPs in accurately capturing rosmarinic acid, illuminating their potential applications in pharmaceutical and analytical settings where precise molecule recognition and extraction methodologies are crucial. This innovative approach not only enhances the extraction process but also opens new avenues for the application of MIPs in various fields, including food chemistry and natural product research. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025.Science Citation Index Expande
Avatar: a Film at the Center of the Feminine Other
This study analyzes James Cameron's 2009 film Avatar from the perspective of the feminine other through deconstruction. In the movie, nature and the Na'vi people are depicted as feminine, while modern man and the science, technology, and military power he represents are portrayed as masculine. Although it critiques the colonialist structure of modernity, the film's narrative structure and character portrayals indicate that it reproduces the superiority of Western-centered ideology and the masculine mind. The study analyzes how the film's narrative and character representations implicitly support masculine centrism. The analysis reveals how nature and marginalized cultures are romanticized and presented in the film and how the notion that the feminine can only survive by adopting masculine traits is processed in the subtext. Grounded in a conceptual and theoretical framework, this research focuses on the sustainability of the patriarchal capitalist system and gender politics while critically examining how cinema reconstructs ideological structures through the narratives in the film
Genç Sporcularda Antrenör ve Aile Kaynaklı Özerklik Desteği Ölçeklerinin Psikometrik Özelliklerinin Değerlendirilmesi: Metodolojik Çalışma
Amaç: Çalışmada, “Antrenör Kaynaklı Özerklik Desteği” ile “Aile Kaynaklı Özerklik Desteği” ölçeklerinin Türkçe formlarının psikometrik özelliklerinin Doğrulayıcı Faktör Analizi (DFA) ile incelenmesi amaçlan- mıştır. Gereç ve Yöntemler: “Antrenör Kaynaklı Özerklik Desteği” ile “Aile Kaynaklı Özerklik Desteği” ölçekleri 7’li Likert tipinde, 12 madde ve tek boyuttan oluşmaktadır. “Antrenör Kaynaklı Özerklik Desteği Ölçeği”nin psikometrik özellikleri 145 erkek ve 63 kız toplam 208 (Xyaş=14,51±2,83), “Aile Kaynaklı Özerklik Desteği Ölçeği”nin ise 164 erkek ve 70 kız toplam 234 (X yaş=14,87±1,92) sporcu üzerinde test edilmiştir. Ölçeklerin yapı ge- çerlikleri DFA ile sınamıştır. Ölçeklerin yakınsak geçerlikleri Birleşik Gü- venirlik [Composite Reliability (CR)] ve Ortalama Açıklanan Varyans [Average Variance Extracted (AVE)] değerleri hesaplanarak test edilmiş- tir. Cronbach alfa iç tutarlık ve CR katsayısı güvenirliğin test edilmesi için hesaplanmıştır. Bulgular: DFA sonuçları her iki ölçeğin de orijinal yapı- sını desteklemiştir (Antrenör; x2/df=3,67, Standartlaştırılmış Hata Kareleri Ortalamasının Karekökü [Standardized Root Mean Square Residual (SRMR)]=0,04, Normlu Uyum Indeksi [Normed Fit Index (NFI)]=0,90, Fazlalık Uyum İndeksi [Incremental Fit Index (IFI)]=0,91, Karşılaştırmalı Uyum İndeksi [Comparative Fit Index (CFI)]=0,91, Aile; x 2 /df=3,71, SRMR=0,03, NFI=0,91, IFI=0,95, CFI=0,95). AVE ve CR değerleri ölçek- lerin yakınsak geçerliğini destekler niteliktedir. “Antrenör Kaynaklı Özerk- lik Desteği Ölçeği”ne ait Cronbach alfa ve CR değerleri 0,93 olarak bulunmuştur. “Aile Kaynaklı Özerklik Desteği Ölçeğinden elde edilen Cron- bach alfa ve CR değerleri 0,96 olarak bulunmuştur. Sonuç: Elde edilen bul- gular ile 12-18 yaş arası sporcuların antrenör ve aileden algıladığı özerklik desteğinin değerlendirilmesi amacı ile çalışmada psikometrik özellikleri test edilen ölçeklerin güvenilir ve geçerli bir araç olduğu söylenebilir
Systematic Review of Clinical Outcome Parameters of Conservative Treatment of Adolescent Idiopathic Scoliosis Patients
Kuru Colak, Tugba; Akcay, BurcinBackground: The purpose of this systematic review was to investigate the clinical outcome measures, either in separation or in conjunction with the Cobb angle, that were employed in randomized controlled trials to evaluate posture and spinal deformity. Methods: The PubMed, PEDro, OVID, and Scopus electronic databases were used to search for published articles from January 2004 to May 2024. All the searches included English language studies. Keywords were determined as "scoliosis, exercise, physical activity, brace, bracing, conservative treatment, rehabilitation, physiotherapy and physical therapy". Results: The most commonly used clinical evaluation parameters other than the Cobb angle in the studies were the ATR and surface topography measurements. The most commonly used assessment methods were POTSI asymmetry assessment performed with measurements made on photographs, the WRVAS, a deformity perception assessment evaluated with different photographs, and the SRS-22 scale, a disease-specific quality of life assessment. Conclusions: New developments in the treatment of scoliosis have brought about alternative measurement techniques that offer a more comprehensive view of patient outcomes. As a result of the review of the literature, it has emerged that radiation-free, valid, and reliable multidimensional evaluations should be performed in follow-up and treatment efficacy evaluations after initial diagnosis in adolescent idiopathic scoliosis.Science Citation Index Expande
Development and Preliminary Psychometric Properties of the Adolescent Sleep Health Belief Scale
AIM: This study aimed to develop a scale based on the Health Belief Model that can reliably and validly evaluate adolescents’ beliefs toward sleep. METHODS: This study was conducted using a methodological design with 494 adolescents between September and October 2022 in Antalya, Türkiye . Eighty-one items about sleep were created according to the Health Belief Model. Validity was assessed in terms of content and construct validity, and reliability was assessed through internal consistency. Content validity was evaluated by ten expert opinions. The scale was tested for construct validity with exploratory factor analysis, after which the scale’s reliability was evaluated by examining item-total correlations using Pearson’s correlation analysis and assessing internal consistency with Cronbach’s Alpha. RESULTS: Item-level content validity index scores ranged between 0.80 and 1. The scale-level content validity index value was found to be 0.94. In the exploratory factor analysis of the 46-item scale, six factors were found with an eigenvalue greater than 1, explaining 57.7% of the total variance. The scale’s itemtotal correlations ranged from 0.26 to 0.79. Cronbach’s alpha coefficients for the subscales were 0.92 for perceived susceptibility, 0.90 for perceived severity, 0.90 for perceived benefits, 0.81 for self-efficacy, 0.79 for motivation, and 0.69 for perceived barriers. CONCLUSION: The Adolescent Sleep Health Belief Scale demonstrated good validity and reliability in adolescents. Its cross-cultural adaptation for use with adolescents in other countries is recommended. © 2025, Istanbul University-Cerrahpasa, Florence Nightingale Faculty of Nursing. All rights reserved
Comparison of the Effectiveness of Connective Tissue Massage and Classical Massage in Patients with Migraine
Biocompatibility Assessment of Chlorhexidine Gluconate Versus a Natural Mouthwash Containing Olea Europaea and Opuntia Ficus-Indica in Zebrafish Embryos
Various chemical solutions are available for oral hygiene and care, but these chemical solutions also cause various side effects in living systems. Therefore, the trend towards the production of highly biocompatible, natural-based oral care products has increased. This study aimed to compare the biocompatibility profiles of a conventional chlorhexidine gluconate-based mouthwash and a natural formulation containing Olea europaea leaf and Opuntia ficus-indica extracts using the zebrafish embryo model. Zebrafish embryos were exposed to two concentrations (100 ppm and 1000 ppm) of each mouthwash for 72 hours post-fertilization. Developmental properties such as mortality, hatching rate, pericardial edema, and body length were evaluated. Biochemical analyses included oxidative stress parameters and acetylcholinesterase (AChE) activity. Chlorhexidine exposure resulted in increased embryonic mortality, pericardial edema, and reduced body length. Biochemically, chlorhexidine increased lipid peroxidation and glutathione S-transferase (GST) activity while decreasing superoxide dismutase (SOD) and AChE activities. In contrast, embryos exposed to the natural formulation showed no significant developmental abnormalities and exhibited increased SOD and AChE activities without changes in lipid peroxidation. These findings provide evidence regarding the differential biocompatibility of synthetic and plant-based mouthwashes in early developmental models