Atılım Academic Archive (Atılım University)
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Glycaemic Control and Complications in Haemodialysis Patients: The TURK-HEMODIAB Study
No full textBackground The most common cause of end-stage kidney disease is diabetes mellitus (DM). The most commonly used renal replacement therapy in Turkey and in many countries around the world is haemodialysis (HD). Glycaemia control is important in these populations. In this study we aimed to screen for glycaemic control and complications in a large population of diabetic HD patients in Turkey. Methods A total of 16 043 patients were screened in 253 dialysis centres in Turkey and 5038 diabetic HD patients were included in the study. At participating centres, patients' diabetes history, complications, medications, haemoglobin A1c (HbA1c) and other laboratory data were reviewed and recorded by nephrologists. Results The average age of the patients was 64.0 +/- 11.2 years and 56% were male. The mean HbA1c was 7.4 +/- 1.5%. Patients were divided into three groups according to the HbA1c level (8%). As the HbA1c levels increased, the mean systolic blood pressure and diastolic blood pressure increased significantly. In addition, as the HbA1c levels increased, the number of patients with coronary artery disease, patients undergoing coronary artery bypass graft surgery and the rate of patients with diabetic retinopathy and vision loss increased. Diabetic foot disease and amputation rates were also higher in the group with poor glycaemic control. The number of patients using intensive or mixed insulin was also higher in the group with high HbA1c levels. In ordinal logistic regression analysis, age significantly decreased and higher body mass index slightly increased the risk of a higher HbA1c. Also, the need for a diabetic diet was greater in those with high HbA1c levels. Conclusion Our study highlights that the target values for diabetic HD patients in Turkey are partially compatible with the 2022 Kidney Disease: Improving Global Outcomes guidelines for diabetes management. Nevertheless, more effort and teamwork are needed to improve patient outcomes
Reply to Letter to the Editor: Critical Appraisal of Caval Valve Implantation Procedure in 7 Cases of Torrential Tricuspid Regurgitation
No full textMobile Payment Adoption During the COVID-19 Pandemic: A Systematic Literature Review
No full textDuring the pandemic, the shift to non-physical transactions increased the need for mobile payments. This study aims to offer a systematic literature review on consumer behavior towards mobile payment during the pandemic, using the Theory, Context, Characteristics, and Methodology framework and following the Scientific Procedures and Reasons for Systematic Literature Reviews protocol. 47 articles from the WOS database were analyzed, revealing a dominance of quantitative studies, primarily based on the Technology Acceptance Model and UTAUT. Findings show that environmental stimuli and internal states (organism) shape behaviors and behavioral intentions (responses) towards mobile payments during the pandemic. The study concludes with future research directions grounded in the TCCM framework
Creative Design Engineering Education for Human-Society Integrated Intelligent Systems
No full textThe essence and vital roots of scientific activities create theoretical propositions and models that provide unique integrity of the associated concepts, definitions, approaches and methodological components. Design engineering education has made great progress to date by integrating modern methods and tools into the existing process models focused on unique curriculum programs for students' progress during various scientific and technical levels. Contemporary and integrated socio-scientific environments, however, are generally more productive and initiative for future success stories of engineering graduates with high qualifications and science/technology-motivated professional life. Today's global transition from the "industrial-digital age" to the "sustainable knowledge economy and digital society" opens a new path for design engineering education, enforcing a paradigm shift towards training creative professionals who develop and implement new knowledge in real-world social environments. This paper presents and discusses the models, methods and tools to establish a road-map into next-generation creative design engineering education paradigm
Linear Two-Dimensional Consecutive K-Type Systems in Multi-State Case
No full textIn the context of consecutive k -type systems, multi-state system models are only considered in the one-dimensional case and not in the two-dimensional case due to the complexity involved. In this paper, we consider several linear two-dimensional consecutive k -type systems in the multi-state case for the first time, as generalization of consecutive k -out-of- n systems and l -consecutive- k -out-of- n systems without/with overlapping. These systems include multi-state linear connected-(k , r)-out-of-(m, n): G systems, multi-state linear connected-(k , r)-or-(r , k)-out-of-(m, n): G systems, multi-state linear l -connected-(k , r)-out-of-(m, n): G systems without/with overlapping, and multi-state linear l -connected-(k , r)-or-(r , k)-out-of-(m, n): G systems without/with overlapping. We then derive their reliability functions by using the finite Markov chain imbedding approach (FMCIA) in a new way. We also present several examples to illustrate all the results developed here. © 2026 Elsevier Ltd
Hagia Sophia's Reconversion: Turkey's De-Europeanization through Lefebvre's Spatial Triad
No full textHagia Sophia, as a monument of enduring historical and cultural significance, has long stood at the intersection of religious, spatial, and political transformations. Its successive conversions - from basilica to mosque, from museum to mosque again - constitute the layers of its multidimensional character and reflect its symbolic role beyond mere architecture as a palimpsest of meanings. Throughout history, sovereignty over Hagia Sophia has embodied hegemonic power, with its spatial reconfigurations serving political concerns and ideological narratives. This article argues that Turkey's recent de-Europeanization is materially and symbolically manifested in the 2020 reconversion of Hagia Sophia into a mosque. By situating this transformation within Lefebvre's triadic spatial model-perceived space, conceived space, and lived space, the study conceptualizes Hagia Sophia as a paradigmatic site where space, power, and politics intersect, offering an interdisciplinary framework that links the politics of Europeanization with the spatial production of power
Trends and Scientific Evolution in Endovascular Aneurysm Repair (EVAR) Research: A Comprehensive Bibliometric Study Using Vosviewer
No full textBackground: Endovascular aneurysm repair (EVAR) has become a standard treatment for abdominal aortic aneurysms. However, the evolution of EVAR research and its global landscape remain underexplored. This bibliometric analysis aims to map publication trends, identify key contributors, and analyze thematic shifts in EVAR literature over the past three decades.Methods: Data were collected from the Web of Science Core Collection (SCIE) in May 2025. A total of 4264 original research articles on EVAR were analyzed using VOSviewer for co-authorship, co-citation, and keyword co-occurrence mapping. Citation trends, geographical distribution, and institutional contributions were also assessed.Results: Research on EVAR showed steady growth, with a peak of 295 publications in 2024. The United States contributed the largest share (33.02%) of publications. Prolific authors such as Schermerhorn and Verhagen, affiliated with leading institutions like Harvard University, played a pivotal role in advancing the field. Keyword analysis revealed a shift from technical terms (e.g., "stent graft") to clinical outcomes (e.g., "reintervention") over time. The integration of artificial intelligence (AI) in EVAR research is emerging as a key focus area.Conclusion: This study highlights the growth and evolving focus of EVAR research, with a notable shift toward patient-centered outcomes. Despite strong contributions from high-income countries, there is a significant gap in research from low-resource settings. Future directions should include addressing gaps in radiation safety, emergency EVAR applications, and exploring AI-driven clinical decision-making for personalized treatments. Complex EVAR research continues expanding, reflecting guideline evolution and advancing practice in anatomically challenging cases.Clinical Impact This bibliometric analysis demonstrates how EVAR has progressed from an emerging minimally invasive technique to a guideline driven standard of care, with a growing emphasis on complex fenestrated and branched procedures. For clinicians, the findings clarify where the evidence base is well established, particularly for standard infrarenal EVAR, and where further caution and innovation are required, including complex anatomies, long term durability, and reintervention risk. By synthesizing influential studies, key guideline milestones, and evolving research themes, this study supports evidence based clinical decision making, improves patient counseling, and reinforces the importance of lifelong surveillance. Its innovation lies in translating three decades of global research into clinically actionable insight
On Reliability of Consecutive k-out-of-n:G System Equipped With Protection Blocks
No full textThe linear consecutive k-out-of-n:G system consists of n linearly ordered components such that the system works properly when there exists at least k consecutively working components. This paper is concerned with the reliability evaluation of the linear consecutive k-out-of-n: G system equipped with protection blocks. Protection blocks which have their failure rates are used to increase the system reliability. The closed-form expressions for the system reliability when 2k >= n are obtained when the most critical components, i.e. the components that have the highest importance levels are involved by the protection blocks. Numerical examples are provided to illustrate the closed-form reliability equations
The Effect of Cerium Oxide on Liver and Kidney in Lower Extremity Ischemia Reperfusion Injury in Streptozotocin -Induced Diabetic Mice
No full textIntroductionIschemia-reperfusion injury (IRI) is a major concern in diabetic patients undergoing vascular procedures, causing significant damage to the liver and kidneys. The purpose of this study was to evaluate the protective effects of cerium oxide on the liver and kidneys of diabetic mice with lower extremity IRI.Materials and MethodsThirty Swiss albino mice were divided into five experimental groups: control (C), control diabetes (D), diabetes with cerium oxide (D-CEO2), diabetes with IRI (D-IRI), and diabetes with IRI treated with cerium oxide (D-IRI-CEO2). Diabetes was induced with streptozotocin (125 mg/kg) and lower-extremity IRI was induced by clamping the infrarenal aorta. Cerium oxide was administered intraperitoneally to the 0.5 mg/kg cerium oxide groups 30 min before ischemia. Liver and kidney tissue samples were subsequently analyzed through biochemical assays measuring the total antioxidant status, total oxidant status, oxidative stress index, and paraoxonase-1, as well as histopathological examinations.ResultsThe D-IRI group exhibited greater liver and kidney damage than the control group. The D-IRI-CeO2 group displayed reduced liver and kidney damage compared to the D-IRI group. In both the D-IRI and D-IRI-CeO2 groups, the total oxidant status, oxidative stress index, and paraoxonase-1 acitivity were higher, whereas the total antioxidant status levels were lower. In the D-IRI-CeO2 group, there was a decrease in total oxidant status, oxidative stress index, and paraoxonase-1, whereas total antioxidant status increased compared to D-IRI.ConclusionIntraperitoneal cerium oxide reduces oxidative stress and mitigates liver and kidney damage in diabetic mice subjected to lower extremity ischemia-reperfusion injury
A Review on Membranes for Anion Exchange Membrane Water Electrolyzers
No full textAnion exchange membrane water electrolyzers (AEMWEs) - using water and renewable electricity as the input - provide a sustainable pathway to hydrogen production. AEMWEs perform the cathodic hydrogen evolution reaction (HER) and anodic oxygen evolution reaction (OER) with modest overpotentials at practical current densities (>1 A cm(-2)). The recent catalysis, component, and system-level breakthroughs have enabled significant improvements in current densities and energetic efficiencies. The challenge, however, is to maintain these impressive activities and efficiencies through long-term operation at scale. High-performance, efficient, stable, and economically viable AEMWEs require high-performance, low-cost, and scalable anion exchange membranes (AEMs). This Review provides an overview of physical, chemical, and transport properties of commercial and non-commercial AEMs. The article discusses the operating principles, structures, characteristics, strengths, and weaknesses of conventional and emerging AEMs, along with their performance and stability implications in AEMWEs. The article highlights the characteristics that have intricate implications on performance, stability, and cost. It discusses recent advances and best practices to combine high-performance, efficiency, stability, and low-cost in a single AEM structure. The Review highlights the trade-offs between AEM characteristics, with an overview of emerging approaches that would overcome performance, stability, and cost challenges. The Review concludes by highlighting the research gaps and providing research directions with the potential to take the technology a step closer to wide-scale deployment.Scientific and Technological Research Council of Turkey (TUBITAK) [123M878]This work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK) 1001 Project (Grant number: 123M878)