Atılım Academic Archive (Atılım University)
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Factors Influencing the Transition Time From Psoriasis to Psoriatic Arthritis: A Real-World Multicenter Analysis
No full textYurdakul, Ozan Volkan/0000-0003-4567-8133To identify clinical and demographic predictors associated with the timing of transition from psoriasis (PsO) to psoriatic arthritis (PsA), and to compare the characteristics of patients with concurrent PsO-PsA onset versus those with prolonged transition. A multi-center, observational study was conducted using data from the Turkish League Against Rheumatism (TLAR) network including PsA patients fulfilling CASPAR criteria. Patients were categorized into two groups: Group 1 (concurrent PsO and PsA onset within +/- 1 year) and Group 2 (prolonged transition to PsA, > 1 year after PsO). Demographic, clinical, and laboratory characteristics, disease activity, and patient-reported outcomes were compared between groups. Logistic regression was employed to determine independent predictors of prolonged transition. Among 799 patients (mean age 46.8 +/- 12.3 years), 237 (29.7%) had concurrent onset and 562 (70.3%) had a prolonged transition, with a mean PsO-to-PsA interval of 12.9 +/- 9.6 years. Depression (p = 0.005) and fatigue levels (p = 0.011) were significantly higher in patients with prolonged transition to PsA. Multivariate analysis revealed that scalp psoriasis (OR = 7.162), nail psoriasis (OR = 3.270), family history of PsO (OR = 1.813), and enthesitis ever (OR = 2.187) were associated with prolonged transition. Conversely, family history of PsA (OR = 0.421) and older age at PsO onset (OR = 0.957) predicted shorter transition. Prolonged transition from PsO to PsA is influenced by distinct clinical and demographic factors. Scalp/nail psoriasis, family history of PsO, and enthesitis ever may signal higher risk for prolonged PsA onset. Recognizing these markers can support timely referral and intervention, minimizing diagnostic delay and improving long-term patient outcomes
Türkiye'deki Depremzedelerde Ağrı Şiddeti, Hareket Korkusu ve Düşme Korkusu: Kesitsel Gözlemsel Çalışma
No full textAmaç: 6 Şubat 2023'te Türkiye'deki 11 ilde meydana gelen yıkıcı depremler, hayatta kalanlar üzerinde önemli fiziksel ve psikolojik etkiler bırakmıştır. Bu çalışma, depremzedelerde ağrı şiddeti, hareket korkusu ve düşme korkusunun sıklığını belirlemeyi ve bunların birbirleriyle olan ilişkilerini, ayrıca psikolojik dayanıklılık ve fiziksel aktivite düzeyi ile bağlantılarını incelemeyi amaçlamaktadır. Yöntemler: Bu gözlemsel, kesitsel çalışmaya, deprem öncesinde ağrısı veya fiziksel travması bulunmayan 184 hayatta kalan (93 erkek, 91 kadın; yaş ortalaması: 34,02 ± 10,76 yıl) dahil edilmiştir. Ağrı şiddeti, hareket korkusu, düşme korkusu, fiziksel aktivite düzeyi ve psikolojik dayanıklılık sırasıyla ‘Sayısal Ağrı Skalası’, ‘Hareket Korkusu Nedenleri Ölçeği’, ‘Modifiye Düşme Etkililik Ölçeği’, ‘Uluslararası Fiziksel Aktivite Anketi Kısa Formu’ ve ‘Connor-Davidson Dayanıklılık Ölçeği’ kullanılarak 02 Mayıs 2023 ile 30 Temmuz 2023 tarihleri arasında değerlendirilmiştir. Bu parametreler arasındaki ilişkileri incelemek için Pearson korelasyon analizi uygulanmıştır. Bulgular: Katılımcıların %46,7’sinde hareket korkusu, %33,2’sinde düşme korkusu ve %37,7–50,5’inde orta ila şiddetli ağrı gözlenmiştir. Hareket korkusu, baş ağrısı (r = 0,275, p 0,05). Sonuç: Deprem sırasında fiziksel travma geçirmeyen ve önceden ağrısı olmayan hayatta kalanlar arasında hareket korkusu, düşme korkusu ve ağrı şiddeti yaygındır. Bu faktörler, fiziksel aktivite düzeyinden bağımsız olarak birbirleriyle yakından ilişkilidir. Psikolojik dayanıklılık, korkuya bağlı tepkilerde kritik bir rol oynamaktadır. Bu bulgular, afet sonrası rehabilitasyon stratejilerininde ağrı şiddetini ve korkuya bağlı tepkileri ele alırken, psikolojik dayanıklılığının da göz önünde bulundurması gerektiğini vurgulamaktadır
Is Green Servant Leadership a Stronger Predictor of Green Work Engagement and Task-Related Proactive Behaviour Compared to Green Transformational Leadership
No full textRescalvo-Martin, Elisa/0000-0001-8347-6204;The pertinent literature is devoid of research regarding the effects of green servant leadership (GSL) and green transformational leadership (GTL) simultaneously on green work engagement (GWE) and task-related pro-environmental behaviour (TPEB) and GWE as a mediator in the previously discussed associations. Therefore, drawing from social exchange and job demands-resources theories, our paper develops and tests a research model that investigates the interrelationships of GSL, GTL, GWE, and TPEB. Data were gathered from hotel employees in Ankara, T & uuml;rkiye. The hypotheses were tested using partial least squares structural equation modelling. The results suggest that the positive influence of GSL on GWE is stronger than the positive influence of GTL on GWE. As expected, GWE mediates the effects of GSL and GTL on TPEB. More importantly, the indirect positive influence of GSL on TPEB via GWE is stronger than the indirect positive influence of GTL
The Transformation of NATO From Its Foundation to the Present and the Importance of Turkey in the Context of the 2022 Strategic Concept
No full textBu tez, NATO'nun 2022 Stratejik Konsepti çerçevesinde, değişen bölgesel ve küresel jeopolitik gelişmeler ve güvenlik ortamı ışığında Türkiye'nin İttifak içindeki artan stratejik önemini incelemektedir. Bu temelde, NATO'nun kuruluşundan itibaren geçirdiği stratejik dönüşüm, ittifakın genişleme stratejileri, karşı karşıya kaldığı yeni güvenlik tehditlerine yönelik geliştirdiği misyonlar ve ortaya koyduğu hedefler, Türkiye'nin NATO'nun misyonlarına bugüne kadar yaptığı katkılar, NATO'nun Türkiye'ye sağladığı katkılar, Türkiye'nin jeostratejik konumu ve milli savunma sanayindeki gelişmeler analiz edilmiştir. Bu temelde tez, NATO'nun ikinci büyük askeri gücü olmasının ötesinde, sahip olduğu benzersiz jeostratejik konumu, terörle mücadele, enerji güvenliği ve düzensiz göç gibi tehditlerle mücadeledeki başarısı, bölgesel ve küresel istikrarın sağlanmasındaki kilit rolü ve her geçen gün artan milli savunma yetenekleri ile Türkiye'nin NATO'nun 2022 Stratejik Konsepti hedefleri için vazgeçilmez hale geldiğini savunmaktadır. Türkiye'nin İttifak içindeki artan bu önemi, sahip olduğu güçlü ordusu, Rusya-Ukrayna savaşında ortaya koyduğu istikrarlı ve kararlı çabaları ile ABD'de gerçekleşen politik değişimin etkisiyle ortaya çıkan politik değişim ve belirsizlikler neticesinde başta, NATO Genel Sekreteri olmak üzere ABD'li ve Avrupalı siyasetçiler tarafından da teyit edilmektedir. Sonuç olarak bu tez, NATO-Türkiye ilişkilerinin geleceğinin stratejik iş birliği ve gelişen siyasi dinamikler arasında karşılıklı bağımlılık çerçevesinde bir denge ile şekilleneceği sonucuna varmaktadır. Türkiye'nin ayrılmaz rolünün kabul edilmesi ve bu doğrultuda İttifak'ın adil ve tutarlı bir kolektif savunma sağlaması, Avrupa-Atlantik bölgesinin güvenliği için hayati önem taşıyacaktır. Bu tez, Türkiye'nin NATO içindeki konumunun bölgesel ve küresel barış ve istikrarın tesis edilmesinde belirleyici bir faktör olduğu hipotezini desteklemekte ve Türkiye'nin tam katılımı olmaksızın NATO'nun Yenilenen Jeostratejik Dönemi zorluklarına yanıt verme yeteneğinin ciddi şekilde sınırlanacağını savunmaktadır.This thesis examines Turkey's increasing strategic importance within the Alliance in light of changing regional and global geopolitical developments and the security environment within the framework of NATO's 2022 Strategic Concept. On this basis, the strategic transformation that NATO has undergone since its establishment, the Alliance's expansion strategies, the missions it has developed and the goals it has set in response to new security threats, Turkey's contributions to NATO's missions to date, NATO's contributions to Turkey, Turkey's geostrategic position and developments in its national defence industry have been analysed. On this basis, the thesis examines Turkey's unique geostrategic position, its success in combating threats such as terrorism, energy security, and irregular migration, its key role in ensuring regional and global stability, and its ever-increasing national defence capabilities. Turkey's growing importance within the Alliance, its strong military, its stable and determined efforts in the Russia-Ukraine war, and the political changes and uncertainties resulting from the political changes in the United States have been confirmed by American and European politicians, including the NATO Secretary General. In conclusion, this thesis concludes that the future of NATO-Turkey relations will be shaped by a balance between strategic cooperation and evolving political dynamics within a framework of mutual dependence. The recognition of Turkey's indispensable role and the Alliance's provision of fair and consistent collective defence in this regard will be of vital importance for the security of the Euro-Atlantic region. This thesis supports the hypothesis that Turkey's position within NATO is a decisive factor in establishing regional and global peace and stability, and argues that without Turkey's full participation, NATO's ability to respond to the challenges of the Renewed Geostrategic Era will be seriously limited
Neopatrimonial Rule Through Formal Institutions: The Case of Turkey
No full textThis study examines how formal institutions in hybrid regimes, particularly presidentialism, party organization and electoral rules, actively foster and sustain clientelistic networks, leading to particularistic outcomes. While existing literature highlights the weakening of formal institutions and pervasive clientelism as drivers of democratic breakdown, this study uses the concept of neopatrimonialism to analyse how formal institutions themselves consolidate patron-client relationships to maintain power and stability. Focusing on Turkey, the analysis demonstrates that the institutional incentive structure consolidates the president's role as the central ‘patron’, controlling resources and offices, and encourages clientelistic networks to coalesce around the presidency. The discretionary allocation of resources through patron-client relationships sustains neopatrimonial authority as long as clients' loyalty is rewarded. However, this governance increases clients' dependence on the patron, binding them at the expense of representation and responsiveness. The analysis offers insights into how such institutional configurations contribute to authoritarianism and particularistic governance in hybrid regimes. © 2025 Elsevier B.V., All rights reserved.Social Science Citation Inde
A Comparative Study on the Effect of Using a Customized Machine Translation System in Maritime Text Translation Between Turkish and English
No full textMakine çevirisinin (MT) profesyonel çeviri süreçlerine giderek daha fazla entegre edilmesiyle birlikte, MT'nin verimliliği, kullanılabilirlik derecesi ve çeviri sürecini ne ölçüde hızlandırdığı sorgulanmaya başlanmıştır. Bu tezde, genel ve alana özgü verilerin bir araya getirildiği sınırlı bir derlem ile eğitilmiş olan özelleştirilmiş bir MT modelinin, Türkçe-İngilizce dil çiftinde teknik içeriği doğru bir şekilde aktaran ve profesyonel bağlamda kullanılabilir çeviriler üretip üretemeyeceği araştırılmıştır. Özelleştirilmiş iki farklı model, önde gelen çeviri sistemleri (Google Translate, DeepL, Microsoft Translator) ve ChatGPT-4 ile birlikte incelenmiştir. Modellerin performanslarını değerlendirmek için otomatik değerlendirme metrikleri (BLEU, METEOR, chrF++, TER) ve kısa insan yorumları kullanılmıştır. Bu değerlendirme neticesinde, özelleştirilmiş modellerden birinin Türkçeden İngilizceye çeviride rakiplerine kıyasla en yüksek performansı gösterdiği görülmüştür. Sonuç olarak, yapılan özelleştirmenin, özellikle denizcilik metinlerinde daha yüksek terminolojik doğruluk, akıcılık ve yapısal tutarlılık sağladığı görülmüştür. Bu bulgular ışığında, özelleştirilmiş MT'nin özellikle uzmanlık gerektiren alanlarda çeviri verimliliğini ve kalitesini artırabildiği söylenebilir.With the increasing integration of machine translation (MT) into professional workflows, questions have arisen regarding its effectiveness, usability, and how much it accelerates the translation process. This thesis investigates whether a custom MT model, trained on a limited corpus combining general and domain-specific data, can generate translations that accurately convey technical content and are professionally usable within the Turkish-English language pair. Two customized models were evaluated alongside leading commercial systems (Google Translate, DeepL, Microsoft Translator) and ChatGPT-4. To evaluate system performance, automatic evaluation metrics (BLEU, METEOR, chrF++, TER) were used together with brief human commentary. Based on this assessment, one of the customized models outperformed all others in Turkish-to-English translation. Overall, the results indicate that domain adaptation through customization leads to higher terminological accuracy, fluency, and structural consistency, particularly in maritime texts. These findings suggest that custom MT can enhance translation efficiency and quality, especially in specialized domains
A Comprehensive Study of Space Efficiency in Tall Buildings: The Australian Perspective
No full textSpatial efficiency in Australian towers is shaped by a multifaceted interaction of many parameters such as architectural and structural considerations. However, there are no comprehensive studies available on space utilization in Australian high-rise towers. The article addresses this gap by investigating 32 case studies. This study aims to investigate how contemporary Australian tall buildings achieve spatial efficiency by analyzing the relationship between architectural and structural parameters and internal usable area ratios. Key findings: residential function, centrally-located core layouts, and prismatic arrangements are the most widespread trends; concrete is the favored construction material, with the shear-walled frame system being the most commonly used structural system; average space efficiency is 82%, with a core-to-GFA ratio of 16%. The paper offers valuable understandings for construction experts to inform design decisions in high-rise construction projects within the Australian context. © 2025, Kauno Technologijos Universitetas. All rights reserved
Integrating Personalized Thermal Comfort Devices for Energy-Efficient and Occupant-Centric Buildings
Get PDFPersonalized thermal comfort (PTC) systems aim to satisfy the individual thermal preferences of occupants rather than relying on average comfort indices. With the growing emphasis on sustainability and reducing energy consumption in buildings, energy efficiency has become a critical factor in the design and selection of PTC systems. While the development of PTC tools has accelerated in the last decade, selecting the most appropriate system remains a challenge due to the dynamic, uncertain, and multi-dimensional nature of the decision-making process. This study introduces a novel application of the KEMIRA-M multi-criteria decision-making (MCDM) method to identify the optimal PTC system for university office buildings-an area with limited prior investigation. A case study is conducted in a naturally ventilated office space located in a temperate climate zone. Eight distinct PTC alternatives are evaluated, including data-driven HVAC systems, wearable devices, and localized conditioning units. Six key criteria are considered: estimated energy consumption, capital cost, indoor and outdoor space requirements, system complexity, mobility, and energy efficiency. The results indicate that wearable wristbands, which condition the occupant's carpus area, offer the most balanced performance across criteria, while radiant ceiling/floor systems perform the poorest. Energy efficiency plays a crucial role in this evaluation, as it directly impacts both the operational cost and the environmental footprint of the system. The study's findings provide a structured and adaptable framework for HVAC engineers and designers to integrate PTC systems into occupant-centric and energy-efficient building designs.Science Citation Index Expande
Synthesis, Characterization, and Tissue Culture Application of Aloe Vera-Reinforced Hydrogel-Based PVA-PBAT Scaffold for Bone Tissue Engineering
Get PDFDoğal ve sentetik polimerleri birleştiren kompozit iskeleler, sinerjik özellikleri ve hasarlı dokuları onarmak için gelişmiş işlevsellik sunmaları nedeniyle doku mühendisliğinde önemli ilgi görmüştür. Bu çalışma, gelişmiş kemik rejenerasyonu için aloe vera'yı PBAT-PVA iskelelerine entegre ederek yeni bir yaklaşım sunmaktadır. Bu çalışmada, farklı aloe vera konsantrasyonlarıyla karıştırılmış poli(bütilen adipat-ko-tereftalat) (PBAT) ve poli(vinil alkol) (PVA)'dan oluşan hidrojel iskeleler, kemik doku mühendisliği uygulamaları için dondurarak kurutma tekniği kullanılarak üretilmiştir. İskeleler, fonksiyonel grup etkileşimlerini doğrulamak için Fourier dönüşümlü kızılötesi spektroskopisi (FTIR), yüzey morfolojisi ve gözenekliliğini değerlendirmek için taramalı elektron mikroskobu (SEM) ve termal kararlılığı ve bozunma davranışını değerlendirmek için termogravimetrik analiz (TGA) kullanılarak kapsamlı bir şekilde karakterize edilmiştir. Ek olarak, mekanik özellikler basma testi ile analiz edilirken, şişme oranı ölçümleri iskelelerin su emme kapasitesini değerlendirmiştir. İskelelere aloe veranın dahil edilmesi, gelişmiş biyolojik parçalanabilirlik, artan gözeneklilik ve iyileştirilmiş biyolojik uyumluluk gibi özelliklerini önemli ölçüde iyileştirdi; bunların hepsi yeni doku rejenerasyonunu desteklemek için kritik öneme sahiptir. MC3T3-E1 pre-osteoblastik hücre hatlarını kullanan bir hücre kültürü çalışması, iskelelerde mükemmel hücre çoğalması ve yapışması gösterdi ve bu da kemik rejeneratif potansiyellerini göstermektedir. Bu bulgular, aloe vera karışımlı PBAT-PVA iskelelerinin, doku oluşumuyla senkronize olarak parçalanırken kemik rejenerasyonunu destekleyebilen, kemik doku mühendisliği için umut verici adaylar olduğunu göstermektedir. Bu çalışma, bu iskelelerin klinik uygulamalarda kemik onarımını ve rejenerasyonunu hızlandırmak için etkili biyoimplantlar olarak potansiyelini vurgulamaktadır.Composite scaffolds combining natural and synthetic polymers have garnered significant attention in tissue engineering due to their synergistic properties, offering enhanced functionality for repairing damaged tissues. This study introduces a novel approach by integrating aloe vera into PBAT-PVA scaffolds for enhanced bone regeneration. In this study, hydrogel scaffolds composed of poly(butylene adipate-co-terephthalate) (PBAT) and poly(vinyl alcohol) (PVA), blended with different concentrations of aloe vera, were fabricated using the freeze-drying technique for bone tissue engineering applications. The scaffolds were thoroughly characterized using Fourier-transform infrared spectroscopy (FTIR) to confirm functional group interactions, scanning electron microscopy (SEM) to assess surface morphology and porosity, and thermogravimetric analysis (TGA) to evaluate thermal stability and degradation behavior. Additionally, mechanical properties were analyzed through compression testing, while swelling ratio measurements assessed the scaffolds' water absorption capacity. The incorporation of aloe vera into the scaffolds significantly improved their properties, including enhanced biodegradability, increased porosity, and improved biological compatibility, all of which are critical for supporting new tissue regeneration. A cell culture study utilizing MC3T3-E1 pre-osteoblastic cell lines demonstrated excellent cell proliferation and adhesion on the scaffolds, indicating their bone-regenerative potential. These findings suggest that aloe vera–blended PBAT-PVA scaffolds are promising candidates for bone tissue engineering, capable of supporting bone regeneration while degrading in sync with tissue formation. This study highlights the potential of these scaffolds as effective bioimplants for accelerating bone repair and regeneration in clinical applications
The Impact of Increases in Housing Prices on Income Inequality: a Perspective on Sustainable Urban Development
No full textUnalan, Gokhan/0000-0003-4456-6201This study examines the impact of housing price increases on income inequality using the dynamic system GMM for OECD countries (2010-2021). We test the hypothesis that housing price appreciation affects income distribution differently based on economic development levels and homeownership patterns. The analysis is conducted both for the entire sample and by dividing countries into two groups based on per capita income, Group 1 (16 countries) with below-median per capita GDP and Group 2 (17 countries) with above-median per capita GDP, to account to account for structural differences in housing markets, financial systems, and wealth accumulation mechanisms. The findings show that rising housing prices help reduce income inequality, especially in countries that are relatively low-income and where more low-income households own their homes. Specifically, our estimates indicate that a one-point increase in the housing price index leads to a statistically significant (p < 0.05) 0.21 percentage point reduction in the Gini change rate in lower-income countries. However, in higher-income countries, the effect of housing prices on inequality is statistically insignificant, suggesting that the relationship between housing markets and income inequality varies across different economic contexts. This insignificance likely stems from countervailing forces: while housing appreciation increases wealth for homeowners, higher housing costs may disproportionately burden lower-income households through rental markets in these economies. The findings highlight the importance of country-specific housing programs that consider homeownership patterns and financial market access in tackling inequality, along with comprehensive public social policies. Our study has implications for policymakers seeking to address inequality through housing market interventions, particularly during the post-2008 recovery period and into the early pandemic phase.Science Citation Index Expanded - Social Science Citation Inde