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    Ofis Mekanlarında Biyofilik Unsur Olarak Gün Işığı

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    Since the emergence of the biophilia hypothesis, research has been conducted on aspects of biophilic design and how they might be applied in interior design. Daylight is one of the fundamental elements of biophilic design and has several physical and psychological impacts on human beings, having practical implications for office interiors. Consequently, this research explores biophilic design in open plan offices, focusing specifically on the impact of daylight on office workers. In order to examine and compare the role of daylight on mood, circadian rhythm, and well-being of office workers within the framework of biophilic design approach, realistic and comprehensive data was collected utilizing evidence-based methods. The study was carried out in real open-plan work environments in a university in Izmir-Turkey, at every hour of the day by regular measurements of sinus rhythm, ECG, oxygen level, sleep tracking, daily intake of daylight, by using smart watches in a specific climate. Questionnaires and photographic analyses were also carried out to support the data. The findings suggest a strong correlation of daylight and its effects on overall wellbeing, with design guidelines for office interiors. This research may help raise awareness on biophilic design as well as daylight as a significant component. Moreover, both designers and leaders of institutions may utilize the findings, in order to design office environments, conducive to users' well-being. The research has various significant implications for future studies, with regards to new opportunities, that combine evidence-based methods with feedback from participants.Biyofili hipotezinin ortaya çıkmasından bu yana, biyofilik tasarımın yönleri ve bunların iç mekan tasarımında nasıl uygulanabileceği üzerine araştırmalar yapılmıştır. Gün ışığı, biyofilik tasarımın temel unsurlarından biridir ve insanlar üzerinde çeşitli fiziksel ve psikolojik etkilere sahiptir, ofis iç mekanları için pratik etkileri vardır. Sonuç olarak bu araştırma, özellikle gün ışığının ofis çalışanları üzerindeki etkisine odaklanarak açık plan ofislerde biyofilik tasarımı araştırmaktadır. Gün ışığının ofis çalışanlarının modu, sirkadiyen ritmi ve esenliği üzerindeki rolünü biyofilik tasarım yaklaşımı çerçevesinde incelemek ve karşılaştırmak için kanıta dayalı yöntemler kullanılarak gerçekçi ve kapsamlı veriler toplanmıştır. Çalışma, İzmir-Türkiye'de bir üniversitede gerçek açık plan çalışma ortamlarında, belirli bir iklimde akıllı saatler kullanılarak günün her saatinde düzenli sinüs ritmi, EKG, oksijen seviyesi, uyku takibi, günlük gün ışığı alımı ölçümleri ile gerçekleştirilmiştir. Verileri desteklemek için anketler ve fotoğraf analizleri de yapılmıştır. Bulgular, gün ışığı ve gün ışığının genel esenlik üzerindeki etkileri ile ofis iç mekanları için tasarım kılavuzları arasında güçlü bir ilişki olduğunu göstermektedir. Bu araştırma, biyofilik tasarım ve bunun önemli bir bileşeni olan gün ışığı konusunda farkındalık yaratılmasına yardımcı olabilir. Ayrıca, hem tasarımcılar hem de kurum liderleri, kullanıcıların esenliğine yardımcı olacak ofis ortamları tasarlamak için bulgulardan faydalanabilir. Araştırma, kanıta dayalı yöntemleri katılımcıların geri bildirimleriyle birleştiren yeni fırsatlar açısından gelecekteki çalışmalar için çeşitli önemli çıkarımlara sahiptir

    Set-Going Chronicles: Rethinking Turkish Cinema Through the Lens of New Cinema History

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    In this article, we propose set-going as a novel concept for studying the experience of visiting filming locations to watch the making of a film. This experience creates a field of interaction between movie enthusiasts and movie professionals. We argue that set-going should be considered as a new trajectory for studying the cultural and social history of cinema. Theoretically, we benefit from the New Cinema History paradigm. Departing from a case study of the Ye ; scedil;il ; ccedil;am era of Turkish cinema (1950s-1980s), we discuss the practice of set-going as embracing a wide range of social and cultural contexts surrounding the production process

    Opening the Black Box of Ai: a Sociological Study of Ai as a Network

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    This study provides a sociological understanding of the production of AI, which is underexplored in the sociology of AI. To achieve this, the study focuses on the AI development process. Utilizing Actor-Network Theory (ANT), this study demonstrates how the development of AI creates a network consisting of both human and nonhuman actors. The sociological literature focuses on how AI is adopted in various social contexts, identifying the social effects of its introduction and use. We investigate AI itself, showing the values and politics that constitute AI sociotechnical systems in the United States. Based on interviews with software engineers residing in Northeastern USA who work on AI and music platforms, the study highlights how humans and nonhuman actors and social forces such as capitalism and imperialism coproduce AI systems. Engineers' technicality-bound worldview plays a crucial role in their interpretation of AI and the drive for efficiency and profit are foundational values that justify including nonhuman actors such as generative AI platforms and datasets as participants in AI networks. This ultimately results in the production of AI sociotechnical systems that recreate values central to capitalism and imperialism.TUBITAK International Research Fellowship Programme [2214-A]This article is derived from the corresponding author's PhD thesis supported by TUBITAK 2214-A International Research Fellowship Programme for PhD Students

    Psychometric Characteristics of the N-Back Task: Construct Validity Across Age and Stimulus Type, Internal Consistency, Test-Retest and Alternate Forms Reliability

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    Age-related impairments are observed in a variety of cognitive constructs, including significant deteriorations in working memory (WM) performance. To measure the WM, the commonly used task in cognitive aging is the n-back. Despite its widespread use, however, its psychometric properties have not been sufficiently studied. Previous research has typically examined construct validity by correlating n-back task measures with other WM tasks and has primarily assessed reliability through test-retest, occasionally including split-half reliability. In this study, we comprehensively examined the psychometric properties of the n-back task by evaluating its construct validity across different age groups (younger and older adults) and stimulus types (verbal and non-verbal) and by assessing reliability through three methods: test-retest, split-half, and alternate forms. Our findings showed similar performance in verbal and non-verbal n-back tasks for both younger and older adults in terms of discrimination ability and reaction time. However, age-related differences favored younger adults, providing evidence for construct validity. In addition, the n-back measures were stable over time, consistent for two halves, and comparable for different forms, demonstrating task. This study provides the first evidence supporting the validity of the n-back task with regard to age and stimulus type, alongside its reliability. These findings have important implications for clinical research and practice, suggesting that the n-back task can be confidently utilized in neuropsychological assessments. © The Author(s) 2025.Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, TÜBİTAK; Izmir University of Economics, (SRP-2018-11

    Effect of Bacillus Calmette-Guerin Instillation Timing on Oncological Survivals After Transurethral Resection of Bladder Tumor

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    Yazici, Sertac/0000-0001-9616-3776; Bolat, Deniz/0000-0001-7338-8737; Bayazit, Yildirim/0000-0001-7598-9667OBJECTIVE To investigate whether the timing of bacillus Calmette-Guerin instillation (TTBCG), which plays a key role in treating non-muscle invasive bladder cancer (NMIBC), after transurethral resection of bladder tumor (TURBT) affects oncologic outcomes. METHODS Patient data obtained from the Urologic Cancer Database-Bladder (UroCaD-B) of Turkish Urooncology Association (TUOA) were evaluated. Data from 292 patients from 12 centers with primary T1HG treated with TURBT and maintenance BCG between 2003 and 2023 were retrospectively analyzed. The population was subdivided according to TTBCG, while recurrence-free survival (RFS) and progression-free survival (PFS) were estimated by log-rank tests and univariable and multivariable regression analyses. RESULTS A total of 292 patients were followed, and 86% (n = 251) of those included in the study were male. The median duration of TTBCG was 38.5 days (19-73). The median follow-up period was 38.4 months (21.5-72.1 months). During follow-up, recurrence was detected in 55 (18.5%) patients and progression was detected in 22 (7.5%) patients. In univariate Cox regression analysis, long TTBCG (> 27.5 days) was found to have a statistically significant effect on the risk of short RFS and PFS (P = .05). BCG-related side effects were not associated with TTBCG (P = .313). Kaplan-Meier analysis showed that there was a significant difference in RFS and PFS between the TTBCG groups (P = .04, P = .011, respectively). CONCLUSION In this retrospective non-randomized study, we showed the negative effects of BCG delay on progression and recurrence in T1HG patients. Therefore, we think that BCG should be instilled within 4 weeks after surgery. UROLOGY 197: 126-132, 2025. (c) 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies

    Historical a Priori as Form of Life: the Rationality of Social Practices in Foucault's Archaeology in Terms of Wittgensteinian Criteria

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    The concept of rule permeates Foucault's methodological formulations concerning the object of his investigation, but he offers few explicit discussions of the epistemological status of such rules. My claim is that the explication of Foucauldian rules in terms of Wittgensteinian criteria clarifies their epistemological status, and thereby enables one to formulate a novel conception of the historical a priori, one that is defensible against recurrent objections which charge that Foucault's theoretical reflections confuse concepts that are distinct. Foucault and Wittgenstein are best seen as articulating a sense of intelligibility in which forms are integral to content and meaning is not abstracted from social practices. 'Form of life' increases the conceptual cogency of 'historical a priori,' whereas the latter delineates what it would be like to take the former's historicity seriously. © Özgür Gürsoy, 2024

    Exploring the Future of Probiotics With Innovations in Delivery Systems and Market Insights

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    Probiotics play a crucial role in human health, biotechnology, and sustainability, driving continuous innovation in scientific and industrial fields due to their beneficial impacts on gut health, immune modulation, and disease prevention. This review aims to explore recent advances in conventional and non-conventional probiotic microorganisms, focusing on their functional mechanisms, innovative delivery systems, and expanding industrial applications. A structured analysis was conducted by reviewing current scientific literature related to conventional and the emerging non-conventional probiotics, as well as an extensive search on their delivery systems and its benefits from a multidisciplinary viewpoint. Key findings highlight that while conventional probiotics are well-established for their roles in gastrointestinal health and immune support, non-conventional probiotics offer unique metabolic and therapeutic potentials, significantly broadening their applicability in personalized medicine, biotechnology, and environmental sustainability. The review also discusses significant advancements in probiotic encapsulation technologies, which effectively enhance probiotic viability, controlled release, and targeted delivery through the gastrointestinal tract. In conclusion, leveraging both conventional and non-conventional probiotics combined with novel delivery strategies presents promising opportunities for future research, improved commercial products and innovative solutions in human health

    Differences Between Patients With and Without Persistent Psa After Radical Prostatectomy in Clinically High-Risk And/Or Locally Advanced Prostate Cancer

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    Objective: This study aimed to identify preoperative and postoperative factors associated with persistent prostate-specific antigen (PSA) following radical prostatectomy (RP) in patients with clinically high-risk and/or locally advanced prostate cancer. Understanding these factors can guide early postoperative management decisions, including adjuvant treatment strategies. Materials and Methods: A retrospective analysis was conducted on 183 patients who underwent RP for locally advanced prostate cancer between 2009 and 2023. Patients were divided into two groups: those with persistent PSA at 1 month postoperatively (group 2, n=43), and those without (group 1, n=140). Preoperative and postoperative variables, including PSA levels, clinical stage, biopsy grade group, tumor volume, and pathological findings, were compared between groups. Results: Patients in group 2 had significantly higher preoperative PSA levels (24.6 +/- 19 ng/mL vs. 15 +/- 15.5 ng/mL, p0.001), advanced clinical stage (>= T2B: 52.6% vs. 32.1%, p=0.032), and higher percentage of positive biopsy cores (p=0.011). Postoperative findings demonstrated a higher tumor volume (20.2 +/- 14.1 cc vs. 10.7 +/- 10.5 cc, p=0.002), tumor density (p=0.005), and positive surgical margins (86% vs. 70%, p=0.025) in group 2. Patients in group 2 had higher rates of lymph node dissection, adjuvant therapy, and early salvage radiotherapy. Conclusion: Preoperative PSA levels, biopsy grade group, positive surgical margins, and advanced pathological stage are critical predictors of persistent PSA after RP. Early identification of high-risk patients enables personalized management plans, including timely initiation of adjuvant therapies, to improve outcomes. Further prospective studies are needed to refine risk stratification models and personalize treatment strategies

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