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    Les contrats de mariage de marchands et le tabellionage de la place de Rouen (1550-1630).Contribution à la prosopographie des acteurs du commerce français et européen.Enquête et méthodologie (1994-1997)

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    Cette synthèse présente une enquête entreprise dans les années 1990 sous la direction de Jacques Bottin (IHMC-CNRS/Ulm) dans le cadre d'un des axes de recherche du laboratoire dirigé par Daniel Roche, l'Institut d'Histoire Moderne et Contemporaine. Elle s'inscrit dans le prolongement des investigations menées par Pierre Jeannin à l'EHESS autour de la culture technique des acteurs de la marchandise en Europe du Nord et du Nord-Ouest et de leurs profils socio-professionnels à l'époque de la première modernité, à partir d'un fonds notarial de premier plan, le tabellionage de Rouen

    Global-scale AI-powered prediction of hydrogen seeps

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    International audienceNatural hydrogen (H2) holds promising potential as a clean energy source, but its exploration remains challenging due to limited knowledge and a lack of quantitative tools. In this context, identifying active H2 seepage areas is crucial for advancing exploration efforts. Here, we focus on sub-circular depressions (SCDs) that often mark high H2 concentration in soils, thought to correspond to deeper fluxes seeping at the surface, making them promising targets for exploration. Coupling open-access Google Earth© images and in-field H2 measurement data, an artificial intelligence model was trained to detect seepage zones. The model achieves an average precision of 95 %, detects and maps seepage zones in new regions like Kazakhstan and South Africa, highlighting its potential for global application. Moreover, preliminary spatial analyses show that geological features control the distribution of H2-SCDs that can emit billions of tons of H2 at the scale of a sedimentary basin. This study paves the way for a faster and more efficient methodology for selecting H2 exploration targets

    Transfert du contrat de travail et perte d'une chance d'acquérir des actions gratuites : décision inédite

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    International audienc

    La médecine légale et l'identification criminelle au Gabon : le cas de l'affaire J.R.

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    According to Professor Robert CARIO, one should not create a decree for every news item. This implies that the effectiveness of repression does not rely on "penal populism" but rather on "restorative justice." As for Gabon, the trend is quite different because the repressive system is not overwhelmed by an excessive list of legal texts, especially concerning forensic medicine. In this area, whether it is a news item or another event, on August 19, 2025, the Public Prosecutor's Office was seized around 1 p.m. by the Nzeng-Ayong police station following the discovery of an unidentified lifeless body in the area known as Nzeng-Ayong Dragage. Given the very advanced state of decomposition of the body, the funeral home contacted rejected the idea of preserving it and proceeded immediately with the burial. A neighborhood investigation conducted by the police revealed that, a few days earlier, on August 13, an operation a police presence had been reported in the area, and gunshots had been heard. This disturbing coincidence prompted the family to file a complaint on August 22 with the Libreville Court of First Instance. This case, far from isolated, raises questions on multiple levels about the usefulness of forensic medicine in Gabon.Selon le Professeur Robert CARIO, il ne faut pas, à chaque fait divers, créer un décret. Ce qui revient à dire que le caractère efficace de la répression ne repose pas sur le « populisme pénal » mais plutôt sur la « justice restaurative ». Pour ce qui concerne le Gabon, la tendance est tout autre car le système répressif n'est pas submergé par une liste pléthorique de textes, surtout en ce qui concerne la médecine légale. Dans ce domaine, fait divers ou fait d'ailleurs, dans la journée du 19 août 2025, le parquet de la République a été saisi aux environs de 13 heures, par le commissariat de Nzeng-Ayong, de la découverte d'un corps sans vie non identifié au quartier dit Nzeng-Ayong Dragage. Compte tenu de l'état des dégradations très avancées du corps, la maison des pompes funèbres sollicitée a réfuté l'idée de conservation de ce dernier et a procédé immédiatement à l'inhumation. L'enquête de voisinage menée par la police a révélé que, quelques jours plus tôt, le 13 août, une opération de police avait eu lieu dans les environs, et que des détonations avaient été entendues. Cette coïncidence troublante a poussé la famille à déposer plainte le 22 août auprès du tribunal de première instance de Libreville. Ce cas, non isolé, interroge à plus d'un titre sur l'utilité de la médecine légale au Gabon

    The Realization Principle (QAU ∞): A Constraint-Based Framework For Quantum Outcome Realization

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    We formulate a constraint-based framework for quantum outcome realization in which realization is treated as a physical, observer-embedded process implemented by admissible quantum channels. Without modifying unitary dynamics or introducing collapse mechanisms, we impose minimal admissibility conditions—complete positivity, compositional closure, observer consistency, record accessibility, and variational selectability—on realization channels. Under these conditions, standard Born-rule measurement statistics are not postulated but are enforced as a necessary consequence of physical admissibility. We further show that multi-agent contradictions of the Frauchiger–Renner type are non-formulable, as the joint observer inferences required for such constructions cannot be jointly instantiated as admissible physical records within a single realization channel. Existing approaches to quantum measurement are thereby exhaustively classified according to whether they deny physical realization, avoid outcome selection, or admit physically selective realization subject to admissibility constraints. The framework does not advance a new interpretation of quantum mechanics; rather, it classifies the space of physically admissible realization mechanisms once outcome definiteness is assumed to be physical. Within this classification, probability assignment, global observer consistency, and the exclusion of certain paradoxical constructions follow as structural consequences rather than independent assumptions

    Selenomethionine mitigation of methylmercury-induced epigenetic and transcriptomic alterations in rainbow trout brain: a toxicogenomic survey

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    International audienceMethylmercury (MeHg) is a pervasive neurotoxicant threatening aquatic ecosystems. Selenium (Se) has been reported to protect fish against the adverse MeHg toxicity, yet molecular investigations of their interaction in the brain remain scarce. This study investigated the molecular effects of dietary MeHg and whether organic Se, in the form of selenomethionine (SeMet), could mitigate MeHg-induced change in the brain of rainbow trout (Oncorhynchus mykiss). A 6-month feeding trial was conducted with diets containing low basal Se (0.3 mg/kg) and no mercury (Hg), supplemented with 2 mg Hg/kg diet as MeHg, alone or combined with 1.5 mg Se/kg diet as SeMet. Gene methylation (reduced representation bisulfite sequencing) and expression (RNA sequencing) were assessed, alongside biochemical quantification of DNA methylation-related metabolites (S-adenosylmethionine, SAM, and S-adenosylhomocysteine, SAH) and oxidative stress-related metabolites (reduced glutathione, GSH, and oxidized glutathione, GSSG). SeMet did not prevent MeHg-induced changes in SAM/SAH levels but mitigated MeHginduced alterations in DNA methylation of genes related to the glutamatergic system, inflammation, and immune response. Transcriptomic analysis revealed antagonistic effects of MeHg and SeMet on energy metabolism pathways, with hypoxia-inducible factor 1 subunit alpha-like 2 identified as a potential key regulator. Although this molecular interaction may reflect SeMet-mediated attenuation of oxidative stress, biochemical data did not confirm changes in GSH/GSSG levels. These findings provide novel insights into the molecular mechanisms underlying MeHg neurotoxicity and its modulation by SeMet in fish brain, highlighting a potential protective role of organic Se against MeHg-induced molecular alterations

    L'obligation alimentaire: étude du droit civil gabonais de 1972 à nos jours

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    Cet article met en lumière l'ensemble des règles juridiques qui s'appliquent en matière de droit à l'aliment au Gaon depuis l'adoption du code civil en 1972 et des différentes réformes que le texte a connu. Il permet de comprendre en effet que le droit à l'aliment est une obligation réciproque qui lie les enfants, les pères et pères et leurs ascendants.International audienceThis article highlights all the legal rules that apply regarding the right to maintenance in Gabon since the adoption of the Civil Code in 1972 and the various reforms the text has undergone. It makes it clear that the right to maintenance is indeed a reciprocal obligation that binds children, fathers, and their ancestors.Cet article met en lumière l'ensemble des règles juridiques qui s'appliquent en matière de droit à l'aliment au Gabon depuis l'adoption du code civil en 1972 et des différentes réformes que le texte a connu. Il permet de comprendre en effet que le droit à l'aliment est une obligation réciproque qui lie les enfants, les pères et pères et leurs ascendants

    Bridging gender gaps in entrepreneurship through diverse learning environments and change tolerance

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    International audienceThis study explores how diverse learning environments (DLE) influence entrepreneurial intentions and the moderating role of gender. By integrating the theory of planned behaviour with the concept of change tolerance, we examine how DLE characterised by cultural and institutional diversity impact students’ entrepreneurial outcomes. Our findings indicate that immersive DLE enhance participants’ perceived behavioural control, fostering proactive entrepreneurial mindsets among both male and female students. Contrary to traditional research highlighting significant gender differences in entrepreneurial attitudes, our results suggest that inclusive learning contexts can mitigate these disparities. This study contributes to the understanding of gender issues in entrepreneurship by demonstrating how educational environments can promote equality and enhance self-efficacy. The implications for business schools are substantial, as fostering DLE can nurture a diverse pool of entrepreneurs, ultimately driving economic growth and social development within various cultural contexts

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