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Le journal littéraire / El diario literario
No full textInternational audienceEl diario personal ha sido sanciado como género literario en los dos últimos siglos, tras diferentes procesos que han variado considerablemente de una tradición literaria a otra. Los contextos francófono e hispanohablante ejemplifican muy bien lo anterior, pues tanto las obras como la recepción de las mismas han experimentado diferencias notables. Este volumen plantea un acercamiento comparativo a estas dos tradiciones diarísticas, desde Henri-Frédéric Amiel hasta Mario Levrero o Andrés Trapiello, con objeto de ilustrar las divergencias y convergencias en el desarrollo de este género autobiográfico.Le journal personnel est un genre littéraire qui n’a été reconnu que progressivement au cours des deux derniers siècles, et dont l’évolution a été sensiblement différente d’une culture à l’autre. Le processus de « littérarisation » qu’il connaît n’aboutit pas exactement aux mêmes formes ni à la même reconnaissance des deux côtés des Pyrénées. Ce volume s’attache, dans une perspective contrastive, à l’étude de ces transformations dans les littératures de langues espagnole et française, d’Henri-Frédéric Amiel à Mario Levrero ou Andrés Trapiello, avec l’objectif d’illustrer les divergences et convergences dans le développement de ce genre autobiographique
Les sonnets d'Albert Samain
No full textInternational audienceAlbert Samain apparait déjà en 1893 un peu démodé par rapport aux innovations du vers libre : « M. Albert Samain s'est permis de composer Au jardin de l'infante selon les habitudes d'une rythmique surannée ou plutôt passagèrement démodée : les personnes un peu irréfléchies qui ne se laissent charmer que par les plus récentes musiques ne se demanderont même pas si le vers orthodoxe et traditionnel convenait mieux pour exprimer la grâce fanée, la grâce langoureuse de cette âme triste, de même que le vers libre traduit nécessairement les amples voluptueuses légendes songées par M. Henri de Régnier et les hagardes et tragiques visions de M. Émile Verhaeren », écrit Pierre Quillard (Samain, 2015 : 580). En effet, celui-ci préfère les formes fixes, dont le sonnet. Il a été considéré par certains lecteurs comme l'inventeur du sonnet à 15 vers. Nous nous sommes donc interrogée sur cette « rythmique surannée » en nous focalisant sur la forme ancienne et continûment renouvelée qu'a travaillée Samain
Les stockages distribués pour diminuer la température d’opération des réseaux de chaleur existants
No full textInternational audiencePour décarboner le secteur de la chaleur, les réseaux de chaleur sont essentiels. La diminutionde leur température d’opération est envisagée pour améliorer leur efficacité et y intégrer davantage desources d’énergie décarbonées. Cela implique la mise à niveau de certains éléments dont les conduitesqui sont confrontées à une augmentation du débit au-delà de la limite recommandée. A l’aide du logicielde simulation numérique DistrictLab-H Simulation Studio, cet article propose l’étude d’une solution demise à niveau encore non déployée sur le terrain qui consiste à ajouter des stockages dits distribués enaval des conduites concernées par ce dépassement de débit
Proportionality of the Penalty of Confiscation: Focus on French and Spanish Criminal Law
No full textInternational audienc
Reproductive success of dispersers depends on the population of origin in Atlantic salmon
No full textInternational audienceAtlantic salmon (Salmo salar) is an iconic species of great socio-economic value, which is also known for its philopatric behaviour called ‘homing’. After spending one to several years in freshwater, juvenilesmigrate to marine areas for growth, remaining there for one to several years before returning as adults to their natal river to reproduce. However, some individuals can disperse to nearby or more distant rivers, leading to a metapopulation functioning. Theory predicts that dispersing individuals may have a lower fitness than local individuals, but this prediction has been rarely investigated in Atlantic salmon. The objectives of this study were to: i) identify the dispersers in a focal population (Nivelle River, France), and ii) compare their reproductive success with local individuals. We combined pedigree and populationgenetic approaches using 4331 individuals genotyped with 14 microsatellites and/or 164 SNPs over a sixteen years period. Population genetic assignment tests coupled with pedigree reconstruction revealed a high dispersal rate of 19.5% into the Nivelle population. Dispersal was male-biased and higher in single-sea-winter salmon than multi-sea-winter fish. On average, reproductive success was 15% lower for dispersing individuals than local ones. However, after accounting for sex and sea age, dispersers from some populations had a higher reproductive success than local individuals. Overall, we show an origin-dependent reproductive success of dispersing individuals, which illustrates the trade-off between gene flow and local adaptation
Synthesis of new 1,3-bis[(4-(substituted-aminomethyl)phenyl)methyl]benzene and 1,3-bis[(4-(substituted-aminomethyl)phenoxy)methyl]benzene derivatives, designed as novel potential G-quadruplex antimalarial ligands
No full textInternational audienceBackground: Based on our previously reported series of novel 1,3,5-tris[(4-(substituted-aminomethyl)phenyl)methyl]benzene and 1,3,5-tris[(4-(substituted-aminomethyl)phenoxy)methyl]benzene derivatives, we have now designed, synthesized, and tested a new series of novel restricted and simplified structural analogues of these compounds against Plasmodium falciparum in vitro; i.e., the 1,3-bis[(4-(substituted-aminomethyl)phenyl)methyl]benzene and 1,3-bis[(4-(substituted-aminomethyl)phenoxy)methyl]benzene compounds.Methods & results: The pharmacological results revealed significant antimalarial activity, with IC50 values in the submicromolar to micromolar range. Additionally, the in vitro cytotoxicity of these new nitrogen-containing polyphenyl- or -phenoxymethylbenzene compounds was evaluated on human HepG2 cells. The compound 1f, the 1,3-bis[(4-(3-(morpholin-1-yl)propyl)aminomethyl)phenoxy)methyl]benzene derivative, emerged as one of the most potent and promising antimalarial candidates, demonstrating a cytotoxicity/antiprotozoal activity ratio of 594 against the chloroquine-sensitive Plasmodium falciparum 3D7 strain. Additionally, the 1,3-bis[((substituted aminomethyl)phenyl)methyl]benzene compound 1j and the 1,3-bis[((substituted aminomethyl)phenoxy)methyl]benzenes 2p and 2q also showed strong antimalarial potential, with selectivity indexes (SI) of over 303, 280, and 217, respectively, against the 3D7 strain, which has mefloquine-reduced sensitivity. Furthermore, the 1,3-bis[(4-(pyridin-2-ylethylaminomethyl)phenyl)methyl]benzene 2k was identified as the most noteworthy antimalarial compound, exhibiting a selectivity index (SI) that was superior to 178 against the chloroquine-resistant Plasmodium falciparum W2 strain. It has previously been suggested that the telomeres of P. falciparum may serve as potential targets for these polyaromatic compounds; thus, we assessed the ability of our novel derivatives to stabilize parasitic telomeric G-quadruplexes using a FRET melting assay.Conclusions: However, regarding the stabilization of the protozoan G-quadruplex, it was noted that the few substituted derivatives, which showed interesting stabilization profiles, were not necessarily the most effective antimalarial compounds against both Plasmodium strains. Moreover, these new compounds did not show promising stabilizing effects on the different G4 sequences. Therefore, no correlation arises between their antimalarial activity and the selectivity of their binding to G-quadruplexes
Insights into the role of the covalent Ni–O bonds in LiNiO 2 positive electrodes: a correlative hard X-ray spectroscopy study
No full textInternational audienceThe interest in Ni-rich layered oxide positive electrode materials has been increasing due to their wide applicability particularly in electric vehicles as high capacity and high energy density electrode materials. However, the Ni–O bond array which builds the overall framework and plays a critical role in the charge compensation mechanism of the material requires deeper understanding. This work presents a correlative approach elucidating the role of the local highly covalent Ni–O bonds in a LiNiO2 (LNO) model material. Pristine and electrochemically obtained LNO positive electrodes are analyzed using ex situ X-ray diffraction (XRD) and extended X-ray absorption fine structure (EXAFS) to compare the average and local structural evolution upon Li+ ion de-intercalation. Insights from Ni K-edge X-ray absorption near-edge structure (XANES) and non-resonant Ni Kb X-ray emission spectroscopy (XES) spectra are combined to track the electronic environment of Ni. X-ray Raman scattering (XRS) spectra at the Ni L2,3-edges and O K-edge provide direct bulk electronic information with regard to the interplay between Ni 3d and O 2p states. The overall findings imply that O plays a significant role in the charge compensation process, contributing to the substantial negative charge transfer from the O 2p orbitals, because of the covalency in the Ni–O bonds inside the NiO2 framework within the edge-sharing NiO6 octahedra. The utilization of complementary X-ray spectroscopy techniques clarifies the intricate electronic environment of LNO, which is helpful in understanding Ni-rich positive electrode materials and offering new insights into their covalent nature
Temporal dynamics of oxylipins and antioxidant metabolites in rainbow trout muscle are driven by diet type rather than methylmercury or selenomethionine supplementation
No full textInternational audienceTuna by-products in aquafeed pose challenges due to heavy metals like mercury (Hg), which has pro-oxidant effects. However, they also contain selenium (Se), an antioxidant oligoelement. This study assessed the oxidative impact of these elements in juvenile rainbow trout over a 6-month feeding trial. Fish were fed plant-based or tuna-based diets, with or without supplementation of methylmercury (MeHg) and selenomethionine (SeMet). Muscle samples were collected at 0, 21, 84, and 168 days to analyze fatty acid profiles, non-enzymatic oxylipins, and antioxidant metabolites (glutathione, vitamin E). Tuna-fed fish exhibited higher oxylipin levels and lower antioxidant metabolites compared to plant-fed fish. Notably, oxylipin levels remained elevated at 84 and 168 days in tuna-fed fish, correlating with a decrease in the GSH:GSSG ratio. In contrast, plant-fed fish showed a transient increase in oxylipins at 84 days, which normalized by day 168, aligning with a temporary drop in the GSH:GSSG ratio. MeHg and SeMet supplementation did not alter these trends. Surprisingly, these findings, along with a previous study, suggest that prolonged oxidative stress in tuna-fed fish is more closely linked to Se bioaccumulation than Hg. Future work should investigate dietary Se concentration and form to better understand these results
Le prestre comporté - Édité d'après le ms. BnF fr. 12603
No full textLe prestre comporté - Édité d'après le ms. BnF fr. 1260
Les trois dames qui troverent un vit 2 édité d'après le ms. Harley 2253
No full textLes trois dames qui troverent un vit 2 - édité d'après le ms. Harley 225