Repositorio Institucional Universidad Finis Terrae
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Objetos olvidados como apariciones de espacios de basura: la presencia del cuerpo precario en el paisaje industrial de Camino Melipilla
No full textEnsayo Crítico (Licenciado en Artes Visuales, Mención Escultura)--Universidad Finis Terrae, 2024Esta investigación se realiza a partir de la observación del paisaje y el recorrido por medio de la caminata para reflexionar sobre los “Espacios Basura”, a partir de “Camino Melipilla” teniendo en cuenta que no es el único espacio basura, pero sí el más vivido o cercano que tuve para explorar y el motor de este proyecto. Los espacios basura son vistos como un espacio de tránsito que imposibilitan la pertenencia, el habitar, pero que son vistos como un contenedor de desechos diversos. El desecho acá es comprendido como un sujeto que se relaciona directamente con el paisaje y cómo se articula, por su materialidad, estado, fragmentación, transformación constante y la relación estrecha con los transeúntes. Acá se recogen los objetos que contienen estas afecciones que respiran y dan la posibilidad de ser un testimonio, una huella o archivo que evidencia la actualidad y ser representada en una instalación artística contemporánea para generar diálogos, nuevas perspectivas de estos paisajes y darle visibilidad a lo invisibilizado por medio de lo concreto y lo sonoro
Reduced C-reactive protein levels after root canal treatment in clinically healthy young apical periodontitis individuals at cardiovascular risk. A prospective study
No full textAim: To determine the systemic inflammatory burden, including hsCRP and its monomeric forms, in patients with apical lesions of endodontic origin treated with root canal treatment (RCT).
Methodology: Prospective pre-/post-study. Apical periodontitis (AP) individuals aged 16–40 were included (N=29). Individuals received RCT and were followed at 1 and 6months. Fasting blood samples were obtained. Apical lesions of endodon tic origin (ALEO) diameter (mm), and periapical index (PAI), were recorded. The serum concentrations of total hsCRP were determined by turbidimetry. Tumour necrosis factor (TNF)-α, interleukin (IL)-6, IL-10, IL-1β, and soluble (s) E-selectin were assessed by Multiplex assay. Additionally, mCRP forms were determined in the serum of AP patients with a baseline moderate to high cardiovascular risk based on hsCRP stratification (hsCRP ≥1mg/L) by immunowestern blot (n=15). Also, CRP isoforms were explored in ALEOs from AP individuals (n=4). Data were analysed with StataV16.
Results: Periapical index and ALEO sizes were reduced at both follow-up visits after RCT (p<.05). Serum levels of TNF-α, IL-6, IL-10, IL-1β, and sE-selectin did not show significant differences. CRP was borderline reduced at 1month (p=.04); however, in AP individuals at cardiovascular risk (hsCRP≥1mg/L), hsCRP and its monomeric isoform significantly decreased at 1 and 6months (p<.05).
Conclusions: High-sensitivity CRP and mCRP are reduced after RCT in AP indi viduals at cardiovascular risk
Evaluation of the Effect of the Technical Guidelines for Chilean Milk Dietary Service on the Microbiological and Nutritional Quality of a Powdered Infant Formula
No full textThe Chilean Technical Manual for Milk Dietary Service (SEDILE) was evaluated to determine its effectiveness in ensuring the microbiological safety and vitamin D adequacy of a commercially available powdered infant formula (PIF) used in SEDILE. The evaluation focused on whether adherence to the manual’s guidelines positively influenced these factors. Both the PIF and the reconstituted PIF (RIF) were found to be free from Cronobacter sakazakii and Salmonella enterica contamination, with levels of total coliforms and Escherichia coli within acceptable limits. Moreover, the vitamin D content in the formula was within the expected range. These findings suggest that following the Chilean Technical Manual for SEDILE contributes to the microbiological safety and nutritional adequacy of RIF in dietary services
A single bout of resistance exercise triggers mitophagy, potentially involving the ejection of mitochondria in human skeletal muscle
No full textAim
The present study aimed to investigate the effects of a single bout of resistance exercise on mitophagy in human skeletal muscle (SkM).
Methods
Eight healthy men were recruited to complete an acute bout of one-leg resistance exercise. SkM biopsies were obtained one hour after exercise in the resting leg (Rest-leg) and the contracting leg (Ex-leg). Mitophagy was assessed using protein-related abundance, transmission electron microscopy (TEM), and fluorescence microscopy.
Results
Our results show that acute resistance exercise increased pro-fission protein phosphorylation (DRP1Ser616) and decreased mitophagy markers such as PARKIN and BNIP3L/NIX protein abundance in the Ex-leg. Additionally, mitochondrial complex IV decreased in the Ex-leg when compared to the Rest-leg. In the Ex-leg, TEM and immunofluorescence images showed mitochondrial cristae abnormalities, a mitochondrial fission phenotype, and increased mitophagosome-like structures in both subsarcolemmal and intermyofibrillar mitochondria. We also observed increased mitophagosome-like structures on the subsarcolemmal cleft and mitochondria in the extracellular space of SkM in the Ex-leg. We stimulated human primary myotubes with CCCP, which mimics mitophagy induction in the Ex-leg, and found that BNIP3L/NIX protein abundance decreased independently of lysosomal degradation. Finally, in another human cohort, we found a negative association between BNIP3L/NIX protein abundance with both mitophagosome-like structures and mitochondrial cristae density in the SkM.
Conclusion
The findings suggest that a single bout of resistance exercise can initiate mitophagy, potentially involving mitochondrial ejection, in human skeletal muscle. BNIP3L/NIX is proposed as a sensitive marker for assessing mitophagy flux in SkM
La condición histórica actual y su impacto en la educación religiosa: una reflexión desde las ciencias sociales
No full textLa Educación Religiosa se enfrenta a un periodo de renovación e innovación en un contexto de transformaciones sociales, políticas y culturales. Diversos autores señalan la influencia del mercado y el consumismo en las identidades religiosas. El artículo examina cómo fenómenos como la "transnacionalización de lo religioso" y la modernización afectan la manera en que las personas experimentan y practican la religión, especialmente entre la juventud. Se destaca la importancia de considerar múltiples dimensiones, como la subjetividad, la individuación y la socialización, en el estudio de estos cambios. Además, se enfatiza la necesidad de mantener una visión crítica para comprender el presente y fundamentar estrategias educativas efectivas en el ámbito de la Educación Religiosa
Fisiopatología y clasificación de los estados de choque
No full textEl choque es una condición de la naturaleza aguda, sindrómica y patológica, y es una manifestación común de muchas formas de enfermedades críticas en la población infantil. Si bien la presencia de hipotensión arterial señala un estado de choque, su ausencia no la descarta. La fisiopatología del choque se basa en los conceptos de entrega de oxígeno, en los factores que regulan esta entrega y en los requerimientos tisulares del mismo (consumo de oxígeno).Sociedad Latinoamericana de Cuidados Intensivos Pediátrico
Admisibilidad de los Recursos Administrativos del Artículo 59 de la Ley n° 19.880 dentro de la primera etapa del procedimiento de cobro de obligaciones tributarias de dinero
No full textArtículo Académico (Magíster en Derecho Público: Transparencia, Regulaciones y Control)--Universidad Finis Terrae, 2024El presente artículo tiene por objeto analizar la admisibilidad del sistema recursivo administrativo general, consagrado en el artículo 59 de la Ley de Bases de los Procedimientos Administrativos, dentro de la primera etapa del procedimiento de cobro de obligaciones tributarias de dinero, sustanciada por el servicio de Tesorerías. A tal fin, procuraremos determinar la naturaleza administrativa o jurisdiccional de dicha fase y las consecuencias que, en el ámbito de la impugnabilidad, se derivan de dicha calificación, mediante el análisis y ponderación de los argumentos que, sobre el particular, se han esgrimido tanto por la doctrina como por la jurisprudencia.The purpose of this article is to analyze the admissibility of the general administrative appeals system, established in Article 59 of the Act of Bases Administrative Procedures, within the initial stage of the tax debt collection procedure, substantiated by the Treasury service. To that end, we will seek to determine the administrative or jurisdictional nature of this phase and the consequences, in terms of contestability, resulting from such classification. This will be achieved by analysing and evaluating the arguments put forward by both legal doctrine and case law on the subject
Chapter 14: Roles and Challenges of 6G for the Human–Computer Interface
No full textNeedless to say, technology flies like time. Within a relatively short span of about 30 years, we have been able to visualize the advent of 2G, 3G, 4G, and, finally today, the whole world is fondly using 5G. It is without a doubt that the 5G network is successfully satisfying customers’ needs, but dealing with the flow of excessive data and massive network densification all around the world has made things difficult for telecommunications and industry digitalization. Thus, the evolution of wireless communication beyond 5G (B5G) or 6G may not only be necessary for future industry growth, encompassing massive digital transformation of several industries, but also certainly plausible. In this context, we will show, for example, that 6G is expected to deal with multi-sensory technologies in order to create new ways for people to interact with each other and with other technologies, in an effort to be updated with the upcoming global sustainability and fairness trends. 6G is believed to be a self-content application of Artificial Intelligence. Thus, as researchers, it is the right time to investigate and discover upcoming 6G technology deliverables, especially for the human–computer interface (HCI). HCI is a multidisciplinary topic of investigation and also a broad term that connects Computer Science, Cognitive Science, and Human Factors Engineering. HCI no longer focuses on the behavior of individual or generic users, but it broadens its base towards organizational and social computing. This chapter aims to clarify the proposed road map that lies ahead, which identifies certain roles of 6G technology for the human–computer interface. It also explores its role in current businesses and organizations. The chapter also unearths key tenets of the literature on the subject as well as helps researchers to discover both identified and unidentified challenges of 6G for HCI. The chapter also intends to identify potential technology challenges that may lie ahead and provide a solution for many upcoming problems and open a new horizon for imminent research on the matter, in order to advance knowledge in these areas. The main purpose of this chapter is to analyze and deliberate the various potentials and flaws of 6G for human–computer interfaces
Noninvasive continuous positive airway pressure is a lung- and diaphragm-protective approach in self-inflicted lung injury
No full textStrenuous spontaneous effort can promote lung and diaphragmatic injury in acute lung injury (ALI), phenomena known as “patient self-inflicted lung injury” (P-SILI) and load-induced diaphragmatic injury, respectively (1–3). Although continuous positive airway pressure (CPAP) can relieve hypoxemia and work of breathing (4), it is controversial if it prevents lung and diaphragmatic injury (5, 6). We aimed to investigate the effects of noninvasive CPAP on lung and diaphragmatic injury in an ALI model compared with unassisted animals
Perfil y caracterización de los consumidores de productos de origen vegetal en Chile
No full textThe consumption trend of plant-based products has increased worldwide due to different reasons, and Chile has been a good example of this trend. Although sustainability, health, nutrition and taste may all seem to be main drivers for flexitarians seeking plant-based food and beverages, to date there is no research that allows characterizing and profiling Chilean consumers of plant-based products. Hence, this work seeks to close this gap. To address this problem, we conducted an online survey of 512 people, mainly focused on the Metropolitan Region and Valparaíso. Using Ward’s method, we identified 3 clusters: (1) Animal friendly, (2) Planet friendly and (3) Healthy lifestyle, where, respectively, animal welfare, care for the environment and concern for health are prioritized