Journal of Health Sciences and Medical Development
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An Overview of Antibiotic Solubility Based on Reconstitution Time
The reconstitution of parenteral antibiotics is the process of mixing antibiotic drugs with sterile solutions for intravenous use. According to Indonesian Nursing Law No. 38 of 2014, Article 33, nurses are authorized to provide limited pharmaceutical services, including assisting in drug reconstitution. Errors in the mixing process can lead to incorrect drug dosages or reduced efficacy. This study aims to describe the solubility of antibiotics based on the reconstitution time of antibiotics in the Medical Intermediate Care (MIC) unit at Dr. Hasan Sadikin General Hospital in Bandung. The research method used is quantitative descriptive correlational, utilizing frequency distribution to assess respondent characteristics, the antibiotics used, and their solubility. Central tendency measures are used to determine the mean solubility of antibiotics based on reconstitution time. A total of 66 samples were collected using accidental sampling techniques. The reconstitution procedure used aquabidest (distilled water) and NaCl. The duration of the reconstitution process affected the solubility of the antibiotics. It was concluded that the reconstitution and mixing procedures for parenteral preparations in the MIC unit did not fully meet Good Preparation standards. Antibiotics such as Cefepime, Vancomycin, Cefotaxime, and Meropenem had relatively longer reconstitution times compared to other antibiotics. Nurses should have the knowledge and skills to perform drug reconstitution according to standards. Hospitals should establish drug reconstitution standards to ensure the quality of medications administered to patients, thus preventing an increase in antibiotic resistance
Analysis of Factors Affecting Healthy Reproductive Behavior in Adolescents in the Digital Era
Adolescents in the digital era face opportunities and challenges in maintaining healthy reproductive behavior due to easy access to information and social media influence. This quantitative cross-sectional study surveyed 320 high school students aged 15–19 in Surabaya, Indonesia, using stratified random sampling. Data collected from April–July 2025 via self-administered questionnaires were analyzed with descriptive statistics, chi-square tests, correlations, and logistic regression. The findings showed that 62.5% of adolescents had good reproductive behavior, which was significantly associated with high knowledge (73.3% vs. 36.8%, p < 0.001), positive attitudes (71.4% vs. 45.5%, p = 0.001), strong parental guidance (80.6% vs. 39.3%, p < 0.001), supportive peer influence (73.7% vs. 46.2%, p = 0.002), and controlled digital media exposure (80.0% vs. 41.4%, p < 0.001). Multivariate analysis identified strong parental guidance (AOR = 3.65; 95% CI: 2.12–6.28) and controlled digital media exposure (AOR = 3.21; 95% CI: 1.85–5.58) as the strongest predictors, followed by high knowledge (AOR = 2.45), positive attitudes (AOR = 1.78), and supportive peers (AOR = 1.92). In conclusion, adolescent reproductive behavior is shaped by a combination of individual, family, peer, and digital factors, with parental guidance and digital literacy emerging as the most critical protective elements. Strengthening family involvement and promoting responsible digital engagement are recommended to foster healthy adolescent reproductive behavior
The Absence of ENT Clinics and Healthcare Access for Residents in Adankwame, Ghana
The idea of bringing ENT services closer to the community remains a key component of reducing the burden of ENT conditions across low and middle-income countries such as Ghana. Yet there remains a shortage of special ENT clinics and specialists to manage these conditions. In light of this, the study aimed to assess the effects of non-existent ENT clinics on residents seeking health care at Adankwame Health Center in the Atwima Nwabiagya North District. A descriptive cross-sectional survey design was used with a quantitative approach. The population for the study was all residents above 15 years who visited Adankwame Health Center within the period of study. With the aid of the convenience sampling technique, 100 respondents were selected for the study. Data collection was done with a well-structured questionnaire after an ethical clearance had been sought from the Institutional Review Committee. The data collected was analyzed into frequency tables, pie charts, and graphs, using data analysis software and SPSS 25.0. The study concluded that general knowledge and awareness of the ENT clinic were high among residents who attended Adankwame Health Centre. Hearing impairments, chronic ENT conditions, and delayed speech were some of the physiological effects identified. Parental depression probably due to children suffering from delayed speech and language was the psychological effect identified in this study. The financial burden was seen in all aspects as respondents complained of the high cost of transportation in seeking ENT care from secondary and tertiary facilities outside the Adankwame community
Determinants of Skin Disease Complaints in Informal Shellfish Workers: A Study from Cinta Damai Village
Clam processing workers often receive limited attention in occupational health discussions, particularly concerning skin disease complaints, which are strongly suspected of being associated with inadequate personal hygiene practices. This study aimed to examine the effect of personal hygiene on skin disease complaints among clam processing workers. Quantitative research design was employed using a cross-sectional approach. The study involved 67 respondents, selected through total sampling. Data was analyzed using univariate, bivariate, and multivariate methods, with logistic regression applied for multivariate analysis. The results indicated that, after controlling for other variables, skin hygiene as well as nail and hand hygiene were significant factors influencing skin disease complaints. Although hair hygiene was not statistically significant, the relationship trend suggested that individuals with poor hair hygiene had a 7.9 times higher likelihood of experiencing skin-related complaints. Among all variables, skin hygiene emerged as the most influential factor, with an Exp(B) value of 34.869, suggesting that workers with poor skin hygiene were 34.869 times more likely to report skin diseases compared to those with good skin hygiene. The model explained 79.7% of the variance in skin disease complaints, indicating a strong influence of personal hygiene. These findings underscore the critical role of personal hygiene in preventing occupational skin diseases among clam processing workers
Influence of Energy Intake and Nutritional Status on Work Productivity Among Construction Workers: A Case Study of the Merdeka Square Revitalization Project, Medan
Workers involved in revitalization projects are vulnerable to reduced productivity due to physically demanding tasks, time constraints, and challenging environmental conditions such as heat, noise, and long hours. These factors can lead to fatigue, stress, metabolic disorders, and poor nutritional intake, which in turn reduce endurance and focus. This study examines the influence of energy intake and nutritional status on work productivity among workers at the Merdeka Square Revitalization Project in Medan City. A quantitative cross-sectional design was used, involving 77 respondents. Data were analyzed using univariate, bivariate, and multivariate logistic regression tests. After controlling for confounders, both energy intake and nutritional status significantly affected work productivity (p < 0.05). Although excess energy intake was not statistically significant (Exp(B) = 1.319; 95% CI: 0.375–4.642), it still posed a 1.3 times greater risk of reduced productivity compared to adequate intake. In contrast, insufficient energy intake was significant (p = 0.030; Exp(B) = 5.375), with a 5.4 times greater risk of lower productivity. Nutritional status, both overnutrition (p = 0.009; Exp(B) = 10.039) and undernutrition (p = 0.002; Exp(B) = 14.898), significantly affected productivity. The Nagelkerke R² value of 0.354 indicates that these variables explain 35.4% of the variance in work productivity
Experience of First Pregnancy at Teenage Age: Scoping Review
Adolescent pregnancy is a significant global concern and a major contributor to maternal mortality across high-, middle-, and low-income countries. The risk of maternal death is considerably higher among younger adolescents. This study aims to review evidence-based findings on the experiences of first pregnancy in adolescence. A scoping review methodology was employed following Arksey and O'Malley’s framework, using the PEOS model to guide the research questions. A systematic search was conducted in Wiley Online Library, EBSCO, ProQuest, and PubMed, selecting relevant studies based on predefined inclusion and exclusion criteria. Findings indicate that adolescent mothers’ experiences during their first pregnancy are influenced by their level of knowledge and the support received from husbands, families, and healthcare providers. Poor parent-child communication is identified as a key factor contributing to adolescent pregnancy. Additionally, adolescent pregnancy has significant health and educational consequences. Preventive measures include health promotion programs and personalized interventions. This review highlights the experiences, influencing factors, impacts, and prevention strategies related to adolescent pregnancy, providing insights for future research and policy development.
Impact of Cupping Therapy on Blood Pressure in Hypertension Patients at Griya Bekam Az-Zahra
Hypertension is a major global health issue, with its prevalence rising annually. It is estimated that by 2025, 1.5 billion people worldwide will suffer from hypertension, and each year, 9.4 million deaths are attributed to hypertension and its complications. The aim of this study was to assess the effect of cupping therapy on blood pressure in hypertension patients at Griya Bekam Az-Zahra in 2024. This quantitative research employed a quasi-experimental design using a one-group pre-test post-test approach. A sample of 20 respondents was selected through accidental sampling at Griya Bekam Az-Zahra. Data were collected via observation sheets, cupping therapy sessions, and blood pressure measurements. Bivariate analysis was conducted using the Wilcoxon test (α = 0.05). The study took place from June 27 to July 4, 2024. Results showed a significant reduction in both systolic and diastolic blood pressure following cupping therapy. The mean systolic blood pressure decreased from 143 mmHg to 122.5 mmHg, and the mean diastolic pressure dropped from 89.5 mmHg to 78.5 mmHg. Wilcoxon test results indicated that wet cupping therapy significantly affects blood pressure, with p-values of 0.000 (<0.05) for both systolic and diastolic pressures. In conclusion, wet cupping therapy can positively influence blood pressure in hypertensive patients. This finding suggests that cupping therapy could be a valuable consideration for holistic nursing interventions, incorporating bio-psycho-social-spiritual care for the community, particularly as a complementary nursing treatment
Social and Behavioral Determinants of Motorcycle Accident Risk Among University Students in Medan, Indonesia
In Indonesia, traffic accidents are a frequent occurrence and a serious problem, involving many fatalities and material losses. Motorcycles are the vehicles most often involved in traffic accidents and often result in fatalities and injuries, especially among students. The occurrence of motorcycle traffic accidents among students in Indonesia is a serious issue that ranks first among the causes of death in the productive age group. This study aims to analyze the influence of various factors on the potential for traffic accidents among college students, including knowledge, attitudes, infrastructure, environment, parental roles, and peer influence. A quantitative design with a cross-sectional approach was used, involving 212 student respondents selected through purposive sampling. Data were collected through questionnaires and analyzed using the chi-square test. The results of the study showed a significant influence of gender (p = 0.000, PR = 2.372), knowledge (p = 0.047, PR = 1.696), attitude (p = 0.039, PR = 1.527), infrastructure and environment (p = 0.032, PR = 0.649), and peer influence (p = 0.042, PR = 1.511) on the potential for traffic accidents among students. However, there was no significant influence of parental support (p = 0.543, PR = 0.746) on the potential for traffic accidents in students. The findings of this study indicate that when these factors are improved, the risk of accidents can be minimized. It can be concluded that safe driving behavior among motorcycle riders influences the incidence of accidents among university students. Therefore, increasing driving safety education and improving social and environmental infrastructure are important aspects of reducing the number of traffic accidents among university students
The Role of Menarcheal Age and Parity in the Development of Uterine Leiomyoma
Uterine leiomyoma is the most prevalent benign neoplasm of the female reproductive tract during the reproductive years; however, its precise etiology remains incompletely understood. Age at menarche and parity have been proposed as potential risk factors, although previous studies have reported inconsistent findings. This study aimed to evaluate the association between age at menarche and parity with the occurrence of uterine leiomyoma. This research employed a case-control design, in which uterine leiomyoma constituted the case group and adenomyosis served as the control group, conducted at PKU Muhammadiyah Hospital Surakarta. The study included 113 participants, comprising 73 cases of uterine leiomyoma and 40 cases of adenomyosis as controls, identified through histopathological records from 2023. Data were assessed using Chi-Square and logistic regression analyses. The findings revealed that most respondents experienced menarche at a normal age and were either primiparous or multiparous. Statistical testing demonstrated a significant association between age at menarche (p = 0.007; OR = 1.65, 95% CI = 1.414–1.939) and the incidence of uterine leiomyoma, whereas parity was not significantly associated (p = 0.384; OR = 1.509, 95% CI = 0.596–3.825). Future studies are recommended to include more balanced sample group proportions and additional risk factors to obtain a more comprehensive understanding of uterine leiomyoma etiology
Factors Contributing to the Utilization of Traditional Medicine in the Treatment of Ear, Nose, and Throat Conditions
The rate of the use of traditional medicine continues to grow worldwide and is the preferred treatment in especially rural communities in developing countries. This study assessed the factors contributing to the utilization of traditional medicine in the treatment of Ear, Nose, and Throat (ENT) conditions in Kumasi. This quantitative study used a descriptive survey study design to answer the research questions. Convenience sampling technique was used in sampling 166 respondents for the study using Yamen’s formula. A questionnaire was developed to gather information under each objective. Data was analyzed using Statistical Package for Social Science Software to present descriptive analysis. Results from the study showed majority of the respondents believed that cultural beliefs influenced the usage of traditional medicine in the treatment of ENT conditions as more than half of the respondents; 141 (84.9%) responded yes to the statement, ‘Traditional medicine is associated with religious and spiritual underpinnings’. Also, cost, spirituality, social relationships, and health workers' interpersonal relationships among others affected the usage of traditional medicine among the respondents. It was therefore concluded that cultural beliefs are a very significant factor that contributes to the usage of traditional medicine in the treatment of ENT conditions. It is therefore recommended that the Ministry of Health in collaboration with the various health directorates in Kumasi should plan and organize a public awareness campaign program to educate the general population about the potential benefits and risks of traditional medicine