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    Correlation Between Thyroid Function and Ambulatory Blood Pressure Monitoring

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    Background: Blood pressure is associated with overt thyroid disorders, but the role of subclinical diseases is not clear, particularly when blood pressure is assessed at the clinical office. Ambulatory blood pressure monitoring over 24 h provides additional clinical information, which correlates with many cardiovascular endpoints. The aim of our work is to examine whether thyroid function is related to systolic and diastolic blood pressure assessed by ambulatory blood pressure monitoring. Methods: We enrolled 3277 subjects from the SardiNIA project. Thyroid function and ambulatory blood pressure monitoring were assessed in all the participants. Results: TSH was associated with average 24 h and daytime DBP in males but not in females, after adjusting for confounders (respectively, Coef −0.192 p = 0.025, and Coef. −0.021, p = 0.018). We found no association between TSH and DBP or SBP during nighttime. Conclusions: Low TSH in males is positively associated with high DBP. Further studies of underlying mechanisms will need to explore our findings

    Air transport

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    R. L. Stevenson’s “The Enchantress” (1889): A Fin de Siècle Cautionary Tale?

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    The Enchantress di R. L. Stevenson racconta “le avventure di un gentleman squattrinato e di una giovane ereditiera”, che si incontrano in Francia, vanno in Inghilterra e poi in Scozia per contrarre “un matrimonio singolare”. La cop- pia si separa il giorno stesso delle nozze dacché la signora Hatfield abbandona il marito per recarsi nelle Americhe. Ci si propone di rileggere il racconto, con attenzione particolare alla sua valenza in termini di critica sociale e di cambia- mento culturale. Indagando se e in che misura il racconto funga da monito per il lettore, se ne sottolinea la rappresentazione di tradizione e convenzione, coi propri limiti e potenzialità, oltre gli stereotipi culturali dominanti nel periodo del fin de siècle

    Resistere per il futuro degli Appennini

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    Volatility analysis: a multifractional approach with mixtures of Beta distributions

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    Volatility estimation has become one of the core activities of financial analysts. At present, the majority of buy and sell operations are run by “computer traders” that use algorithms mainly based on volatility levels in the market. Several analyses argue that the recent “flash crash crisis” are the amplified consequence of volatility variations. Among the various methodologies proposed in literature, fractals are playing a major role in modeling financial series and, in particular, in analysing volatility characteristics. Following this line, we propose a stochastic approach using a random variable to represent the Hurst Exponent H. We adopt an iterative procedure to model H with a mixture of n Beta distributions, where the number of components will depend on the required modeling accuracy. We choose several types of financial market indexes and assets to evaluate the model and show that the proposed methodology can provide a deep insight into the volatility characteristics associated to each one of them

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