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Diagnostic Categories and Historical School Sources: Interpreting Special Educational Needs in an Early 20th-Century Rural School in Sardinia (Simaxis 1912-1914)
No full textThis paper examines signs of special educational needs in the rural school of Simaxis (Sardinia, 1912–1914) based on teacher Erminia Mura’s handwritten assessments. Using ICD-11 diagnostic categories retrospectively, the study highlights early descriptions of learning and behavioral difficulties. It explores how such challenges were observed, classified, and often marginalized in a selective school system that lacked inclusive pedagogical tools
Coppia di offerente e orante dalla fonte sacra Su Tempiesu di Orune, Nuoro - Pair of offerer and worshiper from the sacred spring of Su Tempiesu, Orune (Nuoro)
No full textSi tratta dell'approfondimento di una particolare iconografia della bronzistica figurata sard
Gastroenteropancreatic Neuroendocrine Neoplasms and Celiac Disease: Rare or Neglected Association?
No full textBackground: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are rare tumors originating from neuroendocrine cells in the gastroenteropancreatic system. They are increasingly recognized as being potentially associated with chronic intestinal inflammatory conditions, namely Crohn’s disease and ulcerative colitis. Celiac disease (CD) is an immune-mediated chronic gastrointestinal inflammation triggered by gluten in genetically predisposed individuals. This study aimed to explore the relationship between GEP-NENs and CD, providing a detailed review of the existing literature and addressing the (possible) gaps in current knowledge. Methods: We conducted an extensive search of international databases using relevant keywords, with the last update on 1 November 2024. A total of 19 studies, published between 1983 and 2024, were included: two prospective studies, five retrospective studies, and 12 case reports. Results: Overall, we included 107 GEP-NENs in our analysis. Among the 94 GEP-NENs identified in prospective and retrospective studies, the small intestine was the most common site (88.3%). The small intestine was also the most frequently reported site in the case report series (46.2%), accounting for 13 GEP-NENs in 12 patients with CD. Conclusions: Although most studies on the association between CD and GEP-NENs are heterogeneous, and while some lack crucial data, emerging evidence suggests that screening GEP-NEN patients for CD could offer valuable insights. Testing for the presence of CD might reveal whether the observed association is more than coincidental and possibly pave the way for exploring and understanding the role of chronic inflammation in the tumorigenesis of GEP-NENs in CD
Copper(II) binding properties and anticancer activity of peptide fragments from a β-strand region of angiogenin protein
No full textOrdini di protezione e tutela del minore dopo la riforma Cartabia del processo civile
No full textIl saggio tratta delle modifiche all'istituto degli ordini di protezione civili introdotte con la recente riforma del processo civile
The Down of urbanity
No full textContemporary urban transformations are increasingly challenging the traditional categories through which the urban has been conceptualized, highlighting the need for a critical reinterpretation of its origins. Western urbanity has been, in fact, structured around the dichotomy between nature and culture, identifying the city’s origin as a centralised and hierarchically organized space, a place of power consolidation and surplus accumulation. This study seeks to deconstructs this dominant and monolithic narrative, exploring the hypothesis that urbanity may have first emerged within sacred places, through ritual practices and festive gatherings.
Drawing on the analysis of prehistoric sites such as the Palaeolithic caves, and later megalithic complexes like Göbekli Tepe and Stonehenge, the research shows how these auroral places functioned as social magnets, temporary nodes of aggregation where diverse and territorially dispersed communities would come together to celebrate collective being, consolidate bonds and share symbolic systems and foundational narratives.
This perspective challenges the dualistic and economistic interpretation of the city as a mere tool for territorial control and economic productivity. Instead, it suggests that early forms of urbanity originated from the human need to construct shared meanings through aesthetic, convivial and ritual practices.
Moreover, through an exemplary case study – the ceremonial sites of central Sardinia – the article demonstrates how this mode of inhabiting space has persisted in certain cultures up to the near-contemporary period, revealing that urbanity itself is not a fixed, naturalized or universal form, but rather one that can be expressed through diverse spatial and cultural articulations.
Retracing this trajectory not only helps to destabilize ingrained conception of the city, but also offers tools for rethinking the present and imagining new futures for contemporary urbanities. By acknowledging and valorising the forms of inhabitation that emerge on the peripheries of dominant spatial regimes – within marginal territories and through aesthetic and political practices of spacial reappropriation – this study contributes to a more plural and situated understanding of the urban present and future conditions
PuraStat for gastrointestinal bleeding management: Effective approach for endoscopic prevention and rescue therapy
No full textUnmet needs of Italian centers for pediatric diabetes care: analysis of a survey among pediatric diabetologists facing the national screening program for Type 1 Diabetes
No full textBackgrounds: The incidence of Type 1 Diabetes (T1D) in children and adolescents is increasing by 3-4% per year. Children and adolescents with T1D (CwD) should receive person-centered, specialized treatment from a multidisciplinary team to ensure appropriate care. Italy is the first to implement a countrywide T1D screening program, which will raise the need for funding for specialized pediatric care. The study aims to update the organization of the Italian Centers for pediatric diabetes care. Methods: In 2022, members of the 59 Italian Centers following CwD were invited to complete an email survey regarding the Centers' organization, characteristics, and activities. The questionnaire included information on responders, department organization, team composition, activities, and the organizational structures: department, ambulatory care services (AC), simple operational units (UOS), simple departmental operational units (UOSd), and complex operational units (UOC). Results: The data collected referred to the year 2022. According to the results, 21,318 people with diabetes were treated. Of these, 19,643 subjects (92.1%) have T1D (16,672 were CwD), 387 (1,8%) have Type 2 Diabetes, and 1,288 (6,1%) have other forms of diabetes. Compared to the 2012 survey, a 13% decrease (from 68 to 59 Centers) in the number of pediatric Centers caring for CwD was observed with a parallel increase of total (+ 6.6%) and average (+ 22%) number of CwD per Center. The estimated prevalence of T1D has increased (1.4 vs. 1.7 per 1,000 CwD-2012 vs. 2022). A reduction in numbers for AC (-22%) and UOS (-35%) was observed, whereas UOSd/UOC increased by 50%. Almost 35% of the dietitians and 40% of the psychologists were not permanent members of the multidisciplinary diabetes team. Conclusions: The observed decrease in the overall number of pediatric diabetes Centers, the reduction in specialized and dedicated HCPs, and the concurrent increase in the number of treated CwD in the last ten years indicate an alarming situation for pediatric diabetes treatment in Italy. Furthermore, the projected rise in CwD due to the National T1D screening program emphasizes the need for increased resources for specialized pediatric care of CwD at all stages
Fringe Democracy and the Platformization of the Public Sphere
No full textThis article introduces the concept of «fringe democracy» as a multidimensional phenomenon emerging in the contemporary public sphere when alternative digital platforms (spaces/affordances/governance patterns), marginalized actors (groups/practices/ideologies), and heterodox narratives (contents/imaginaries/representations) challenge liberal democratic processes. Fringe democracy is not merely about the rise of non-mainstream platforms but arises from complex interactions between fringe and mainstream platforms, actors, and narratives (as shown by recent changes in mainstream platform moderation practices, which reduce fringe actors’ dependence on alternative, freer spaces). While some marginalized actors may propose heterodox narratives driven by democratic values, fringe democracy functions as a form of pseudo-democracy from the margins, exploiting democratic participation mechanisms to undermine core democratic principles. This phenomenon spans ideological spectra, although far-right actors have a particularly notable power to weaken liberal democracies through disruptive communication strategies. After defining fringe democracy, the article introduces empirical and theoretical studies highlighting how interactions between mainstream and fringe platforms shape polarized narratives and amplify manipulative practices. Ultimately, the article addresses methodological and epistemological challenges in researching fringe democracy and advocates a strategy (integrating policy interventions, platform regulations, and media literacy efforts) to effectively address issues posed by the evolving digital public sphere within hybrid media systems, balancing freedom of speech with the necessity of safeguarding democracy