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Customer citizenship behavior and customer perceived value in China: the mediating role of value co-creation experience
No full textThe accelerating advancement of the digital economy has shortened the distance between customers and organizations, prompting customers to participate in value creation process. The role of customers has changed from passive receiver to value co-creator. This study explores the impact of customer citizenship behavior (CCB) on co-creation experience and then on customer perceived value (CPV) based on value co-creation theory under the service-dominant logic (SDL). We introduce co-creation experience as a mediating variable and propose a mediated model of CCB on CPV. We then conduct two rounds of data collection with a total of 642 matched questionnaires in virtual brand communities to test the proposed model. The findings show that different dimensions of CCB exert distinct influences on different dimensions of value co-creation experience. Moreover, different dimensions of co-creation experiences have different impacts on CPV. The findings also show that co-creation experience mediates the relationship between CCB and CPV. This study offers theoretical and practical insights for organizations to enhance customers’ roles in value co-creation process.National Social Science Fund of China (Award: 24BGL029
Insights Into How Digital Health Interventions Shape Outcomes for Emerging Adults Living With Type 1 Diabetes: Qualitative Realist Process Evaluation
No full textBackground: Emerging adults living with type 1 diabetes (T1D) need targeted support to equip them with the knowledge and motivation required for self-management, particularly as they transition from pediatric to adult care. While multicomponent digital health interventions have shown promise in addressing their multifaceted needs, traditional effectiveness studies provide little, if any, insights into which components work effectively, how they function, and for whom. Objective: This study aims to explore the implementation of a multicomponent, text message–based digital intervention (Keeping in Touch; KiT) to provide early insights into which components may shape participants’ transition experiences and how. The secondary objective was to explore which subgroups, defined by individual characteristics, may benefit most from the intervention. Methods: Embedded within a broader randomized controlled trial, we conducted a qualitative realist evaluation with intervention-arm participants who had engaged with KiT for a minimum of 3 months. One-on-one semistructured realist interviews were conducted in a teacher-learner cycle to test the initial program theory. The initial program theory included several pathways through which the 5 intervention components (ie, T1D self-management information and suggestions, transition support information, problem-solving support, stress management strategies, and transition reminders) were hypothesized to influence a range of theorized outcomes. Results: A total of 16 interviews were completed with intervention participants. All 5 KiT intervention components were reported to shape participants’ transition experiences positively but to varying degrees. T1D self-management information and suggestions presented a universal positive impact across all participants. However, the effectiveness of problem-solving support and stress management strategies varied depending on participants’ individual characteristics (eg, duration of diabetes, perceived access to information, and baseline diabetes distress). Rather than acting through parallel independent mechanisms, KiT appeared to support participants’ transition experiences via multiple chains of interconnected mechanisms, often beginning with knowledge or reinforcement and contributing to changes in motivation (eg, self-efficacy and diabetes distress). Interview participants described tangible improvement in mechanisms and proximal outcomes (eg, diabetes knowledge and self-efficacy). Conclusions: A multicomponent, text message–based digital intervention could support emerging adults living with T1D during their transition to adult care by enhancing their knowledge and motivation for self-management. Participant subgroups responded differently to various intervention components, which highlights that one-size-fits-all approaches are likely inadequate. Digital interventions should be developed and studied in a variety of subgroups and contexts to optimize their reach. Interventions for emerging adults living with T1D might benefit from targeting those who are more recently diagnosed with relatively lower baseline levels of diabetes knowledge and self-efficacy or higher levels of diabetes distress
Home Health Care Providers’ Readiness to Care for Children and Youth With Complex Medical Conditions: Protocol for a Scoping Review
No full textBackground: Children and youth with medical complexities have chronic conditions, functional limitations, and extensive care needs requiring significant family involvement and frequent health service use. Pediatric medicine has improved their life expectancy, shifting care from acute to home settings. In Ontario, home care is publicly funded and includes nursing, therapy, personal support, and allied health services. However, families continue providing the bulk of care, often at great personal costs. As care complexity increases, so does the reliance on home care providers. Yet, many providers report feeling unprepared due to insufficient pediatric training, lack of supervision, and system-level gaps. Here we applied Weiner’s theory of organizational readiness for change, framing readiness as a shared psychological state involving commitment to and confidence in delivering change, thus helping conceptualize provider readiness as encompassing individual competence, contextual supports, and motivational factors. Despite its importance, provider readiness in pediatric home care remains poorly understood. Objective: We examine how home care providers perceive their readiness to care for children and youth with medical complexities, factors influencing readiness, and strategies proposed to enhance their capacity to deliver safe, coordinated, developmentally appropriate home care. Methods: This scoping review follows the updated Joanna Briggs Institute scoping review methodology and PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines. Articles focusing on (1) children and youth with medical complexities aged 0-18 years receiving home care and (2) with at least one chronic medical condition, and (3) paid home care providers will be searched on MEDLINE, CINAHL, Scopus, ProQuest Nursing & Allied Health, PsycINFO, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews. Gray literature will be searched on Google Scholar and ProQuest (Dissertations & Theses). A 2-stage screening process will be conducted in Covidence, involving title and abstract screening and full-text review by 2 independent reviewers. Data will be extracted using predefined charting categories and analyzed using both qualitative and quantitative approaches. Results: As of May 2025, screening is underway. The review will map key themes across provider types, care settings, and training contexts and identify factors influencing provider readiness including access to training, system navigation supports, and workplace role clarity and chart recommendations or strategies to enhance readiness. Gaps in pediatric-specific competencies and workforce preparation may also emerge. Conclusions: This review will synthesize current evidence on provider readiness in pediatric home care, identifying strengths, challenges, and development areas. Findings will inform provider training, workforce development, and policy strategies to ensure children and youth with medical complexities receive safe, coordinated, effective home care. A deeper understanding of provider readiness will support more sustainable home care systems and improve outcomes for children and youth with medical complexities and their families
Coordinating Attention in Face‐to‐Face Collaboration: The Dynamics of Gaze, Pointing, and Verbal Reference
No full textDuring real‐world interactions, people rely on gaze, gestures, and verbal references to coordinate attention and establish shared understanding. Yet, it remains unclear if and how these modalities couple within and between interacting individuals in face‐to‐face settings. The current study addressed this issue by analyzing dyadic face‐to‐face interactions, where participants ( n = 52) collaboratively ranked paintings while their gaze, pointing gestures, and verbal references were recorded. Using cross‐recurrence quantification analysis, we found that participants readily used pointing gestures to complement gaze and verbal reference cues and that gaze directed toward the partner followed canonical conversational patterns, that is, more looks to the other's face when listening than speaking. Further, gaze, pointing, and verbal references showed significant coupling both within and between individuals, with pointing gestures and verbal references guiding the partner's gaze to shared targets and speaker gaze leading listener gaze. Moreover, simultaneous pointing and verbal referencing led to more sustained attention coupling compared to pointing alone. These findings highlight the multimodal nature of joint attention coordination, extending theories of embodied, interactive cognition by demonstrating how gaze, gestures, and language dynamically integrate into a shared cognitive system
Spatial separation between two sounds affects first-spike latencies of responses elicited by the sounds in the rat’s auditory midbrain neurons
No full textNatural Sciences and Engineering Research Council of Canada (Award: RGPIN-2019-06458
Commentary on: G. Boger’s “A Possible Rapprochement of Informal Logic with Formal Logic”
No full textHydro- and chloroelementation reactions across an iron–carbon bond using heavy group 15 reagents
No full textWe report the first examples of Sb–H bond additions across a metal–carbon bond, giving heterometallic Sb–Fe complexes.Natural Sciences and Engineering Research Council of Canada (Award: RGPIN-2020-04480, RGPIN-2024-04790)Canada Foundation for Innovation (Award: 41099, LOF-212442
Zearalenone at environmental levels promoted ER- positive breast cancer cell lines through the hedgehog pathway
No full textZearalenone (ZEA) has been recognized as a common exogenous nonsteroidal estrogen in environments which possessed a disruptive effect on organisms. Exposure to exogenous estrogen has been revealed to affect breast cancer development. However, whether ZEA exerts estrogenic effects to influence and cause breast cancer is poorly documented. We hypothesized that ZEA might act as an estrogen and causative factor in breast cancer, mainly due to its similarity to naturally occurring estrogens. The aim of this study was to further explore the potential risks of ZEA by comparing the effects of ZEA on the proliferation and invasion of estrogen receptor (ER) positive/negative breast cancer cell lines, and to explore its underlying molecular mechanisms. We found that low ZEA concentrations, similar with the real environment, promoted the proliferation, migration and invasion only in ER-positive breast cancer cells, while high concentrations of ZEA inhibited malignant biological behaviors in both ER positive and negative breast cancer cells. Consistently, ZEA demonstrated the same biphasic effect (promotion at low dose and inhibition at high dose) on cell stemness and epithelial mesenchymal transition processes, which were further confirmed to be controlled by the Hedgehog pathway. These results highlight the additional health risks posed by ZEA, which warrant greater attention in environmental management.National Natural Science Foundation of China (Award: 3216050055)National Natural Science Foundation of China (Award: 32360165)National Natural Science Foundation of China (Award: U1902202)National Natural Science Foundation of China (Award: 32060161)Yunnan Provincial Science and Technology Department (Award: 2019FA043)NSERC (Award: RGPIN-2023-03736
One for all and all for one health: Harmonizing SARS-CoV-2 wastewater surveillance results across a laboratory network
No full textReliable and comparable data from multiple laboratories are essential for networks relying on reverse transcription quantitative polymerase chain reaction (RT-qPCR)-based surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genetic material in wastewater. Large-scale networks, such as those spanning Canada and the United States, depend on multiple laboratories deploying varied methods. However, the comparability of these methods and implications for data interoperability have not been rigorously examined. Split-sample results from an inter-laboratory study conducted across 15 laboratory methods over 15 rounds in Canada were analyzed. This study focused on assessing the consistency of SARS-CoV-2 signal levels, as well as an indicator of fecal content, Pepper Mild Mottle Virus (PMMoV). Linear mixed models and associated intraclass correlation coefficients (ICC) were applied to gain insights to inter and intra-laboratory method variability. Wastewater SARS-CoV-2 signal levels were moderately concordant across laboratories, even without a single standardized protocol (ICC ≈ 0.70, p < 0.01). Laboratories generally distinguished and aligned on different levels of SARS-CoV-2 present in wastewater samples. However, assays targeting PMMoV displayed significant method-specific variability (ICC = 0.22, p < 0.01). This variability may be attributable to differences in standard quantification materials and different partitioning behaviour of PMMoV relative to SARS-CoV-2 within wastewater matrices. These results highlight the robustness of SARS-CoV-2 surveillance methods across laboratories, demonstrating reliable data comparability despite methodological differences. In contrast, PMMoV assays exhibited greater methodological variability, thereby inflating inter-lab PMMoV-normalized SARS-CoV-2 variability. This suggests the need for careful evaluation of the purpose of-and scale at-which PMMoV normalization is applied. Insights into the impacts of SARS-CoV-2 mutations on assay performance highlight the necessity of routine evaluation to ensure methods remain reliable and fit-for-purpose.Ontario Ministry of the Environment Conservation and ParksUniversity of OttawaUniversity of AlbertaUniversity of TorontoMichigan Technological UniversityPublic Health Agency of CanadaTrent Universit