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The Moderating Effects of Teacher Collaboration on the Association Between Teachers' Job Satisfaction and Job Performance
No full textChinese-English Dictionary Enable Select Search My Words Chinese-English Dictionary Enable Select Search My WordsTeacher job performance is crucial to learners' success. Existing research has mostly focused on the association between teachers' job satisfaction and job performance, but few have investigated how teacher collaboration moderates this association. Using the 2018 TALIS data, a globally representative dataset, teacher collaboration, job satisfaction, and their interaction in relation to teacher job performance were explored with a series of multilevel regression models. After controlling for teacher characteristics, teacher collaboration and job satisfaction presented significant, positive, and direct effects on job performance and the interaction effect between job satisfaction and teacher collaboration was also statistically significant. These findings emphasize the priority of creating a collaborative environment in school to increase teachers' job satisfaction and job performance. This is a purely quantitative research based on the dataset from the 2018 Teaching and Learning International Survey (TALIS) conducted by OECD. The participants involved 153,682 lower secondary school teachers nested within 9,059 schools from 48 participating countries/economies. For the past half century, the relationship between job satisfaction and job performance has been the most 'venerable research traditions' (Judge, Thoresen, et al., 2001, p. 376), and the findings revealed mixed results. The relationship between teacher's job satisfaction and job performance has received little attention in educational sector (Yazdanmehr & Akbari, 2015). Moreover, Given the large variability in satisfaction-performance association across studies, researchers seek to investigate the job satisfaction-job performance relationship involving the use of moderators, such as self-esteem (Judge & Bono, 2001), emotional intelligence (Sy et al., 2006) and leadership (Braun et al., 2013), and generally argued that when moderation factors are added, a significant increase in the initial zero-order satisfaction-performance relationship is identified (Bowling, 2007). However, to the best of our knowledge, few studies have investigated the direct relationship between teachers' job satisfaction and job performance, and included teacher collaboration as a factor that moderates the relationship with an international survey dataset. Chinese-English Dictionary Enable Select Search My Words Chinese-English Dictionary Enable Select Search My Word
Investigating Kaiso and TGFβ signaling crosstalk in epithelial-to-mesenchymal transition in triple-negative breast cancer
No full textTriple-negative breast cancer (TNBC) is the most difficult-to-treat breast cancer (BCa) subtype due to its aggressive, highly metastatic nature, and lack of targeted therapies. Increasing evidence implicates the transcription factor Kaiso in TNBC's increased metastatic potential. In mouse xenograft models, Kaiso-depleted TNBC cells formed little to no metastatic lesions in the lungs or liver compared to parental Kaiso-expressing TNBC cells. Furthermore, increased nuclear Kaiso localization correlates with tumors of a higher histological grade and poorer survival. Kaiso has been implicated in metastasis by promoting epithelial-to-mesenchymal transition (EMT), a cellular program that is characterized by the loss of cell-to-cell adhesion and the adoption of mesenchymal properties that promote migration and invasion. While characterizing the mechanisms behind Kaiso's role in EMT, we determined that Kaiso regulates the expression of various proteins in the Transforming Growth Factor Beta (TGFβ) signaling pathway, another potent inducer of EMT that also participates in BCa progression. Interestingly, we also observed that TGFβ1 treatment increases Kaiso expression in our TNBC cell lines. Chromatin immunoprecipitation (ChIP)-PCR analysis of the Kaiso promoter revealed that the TGFβ transcription factors SMAD2/3 bind to the Kaiso promoter directly, indicating that in addition to regulating TGFβ signaling proteins, Kaiso is also a downstream target of TGFβ. To further examine Kaiso's role in TNBC aggressiveness and metastasis, we will fully characterize this Kaiso-TGFβ feedback loop and examine Kaiso and TGFβ expression in TNBC tissues to determine if there is a unique Kaiso/TGF-β signature that could be used as diagnostic/prognostic biomarkers for TNBC
A-Theory or B-Theory of Time? An Aristotelian Answer
Get PDFA-Theory or B-Theory of Time? An Aristotelian Answer
The purpose of this paper is to provide a description of Aristotle’s theory of time, in order to understand if it could introduce a stimulus into the contemporary debate on the nature of time between A-theorists and B-theorists. The first section (§1) of the paper is devoted to a conceptual explanation of these two main positions about the nature of time and their intimate link with eternalism and presentism. The second section (§2) presents the Aristotelian view on the nature of time (Strobach, 1998), considering his analysis on the notion of ‘periods’ (χρόνοι) and ‘instants’ or ‘nows’ (νῦν) and arguing a metaphysical priority of the ‘now’ on the ‘period’. The third section (§3) tries to locate the Aristotelian theory into this contemporary debate, following two different strategies. Initially, it will be argued in favor of Aristotle’s present’s primacy, demonstrating his preference for A-theory of time. Secondly, through the help of an argument from Jeffery Brower (2011), the paper provides an account of Aristotle’s position in a specific debate on the nature of time concerning the problem of ‘temporary intrinsics’, stating an Aristotelian endurantism. In the conclusion, the paper claims the perfect consistency of Aristotle’s present’s primacy with Brower’s argument in favor of Aristotle’s endurantism.
Bibliography
Aristotle. (1995). Physics. Harvard University Press.
Brower, J. (2011). Aristotelian Endurantism: A New Solution to the Problem of Temporary Intrinsics. Mind, 112, 882–905.
Strobach, N. (1998). The Moment of Change: A Systematic History in the Philosophy of Space and Time. Springer Science+Business Media, B.V.
Key words
Aristotle – A-theory – B-theory – endurantism – metaphysics – perdurantis
Great Lakes Focus on Water Quality: vol.2 iss.2
No full textThe I.J.C. will hear the presentations of the four major institutions reporting to it under the Water Quality Agreement from July 19-22 in Windsor, Ontario. This four-day event marks the first time that the Commission has opened such a meeting to the media and general public. The meetings will be held at the Cleary Auditorium and Convention Centre
Safety Practices in Long Term Care Facilities: A Review of the Literature
Get PDFViable, Healthy and Safe CommunitiesTitle: Safety Practices in Long Term Care Facilities: A Review of the Literature Background: Canada's aging population and the shortage of long-term care (LTC) facilities is creating a growing concern for older adults and their families. This is placing additional stress and demand on the already resource-constrained healthcare system, including shortages of care staff/support workers. The shortage of care staff in LTC facilities has grave impact on the safety and quality of care that residents receive. Common safety concerns in LTC facilities include risks for falls, medication errors, nosocomial infections, and pressure ulcers. Purpose: The purpose of this literature review is to explore studies that have been conducted on the relationship between safety practices and resident outcomes in LTC facilities in North America. Method: A literature search was conducted using databases such as CINAHL, ProQuest, PubMeb, Scholars Portal, and Google Scholar. Search terms included"patient safety" "staff shortages" and 'long term care" or "nursing homes". Inclusion criteria included North American literature written in English and published in 2008-2018. Using the search terms listed, the databases yielded 32 results. After reviewing the articles, 15 met the inclusion criteria and were selected for the purposes of this literature review. The literature identified that care provider staffing is associated with quality of care in LTC facilities. The literature also suggested the following safety practices; increased staffing, education and training for care providers, improved communication, maintaining independence in residents, and teamwork strategies. Summary: LTC facilities are charged with ensuring the safety of their residents in their facilities, and therefore, every effort must be made to address safety issues in order to improve the quality of care and quality of life of residents. Key terms: patient safety, patient outcomes, long-term care facilities, care staff, personal support workers, staff shortage
Specialization vs Diversification: The Rise and Fall of Windsor-Essex's Automotive Industry
Get PDFThere is a longstanding debate between economic specialization, focussing on the production of a limited set of goods, and economic diversification, producing a wide variation of goods and services. While economic diversity boasts a stable and resilient economy, specialization claims to lead to rapid growth. This study explores both schools of thought, examining the strengths and weaknesses of both approaches, and applies them to Windsor-Essex as a case study on the city's reliance on the automotive industry. This paper explores the rise of the automotive industry from the 1970s, examines unemployment rates following economic downturns, analyzes the economic state of the city, and hypothesizes on the future of the industry as recent investments in Electric Vehicle (EV) production have been made. This paper determines that Windsor's specialization in the manufacturing industry has been harmful to the city over the past two decades through its volatility and vulnerability following economic shocks; however, the city is being presented with a unique opportunity to pivot to sustainable transportation, an emerging and promising market, if it properly capitalizes on current and future funding
The Paradox of Imprecision: Wittgenstein, Quine, and the Limits of Exactness in Language
Get PDFThe Paradox of Imprecision in Language
Abstract
This paper investigates philosophical questions bearing on the relationship between language and mind, through an analysis of the phenomenon of “efficient imprecision” in language. It is argued that language users’ ability to intuitively connect allegedly imprecise linguistic expressions with definite conceptual information presents a paradox that might lead philosophers, linguists and cognitive scientists alike to reconsider the relationship between the computational machinery of human language and its function as the vehicle of conscious thought.
Like the puzzle about the identity relation which Gottlob Frege presents in the seminal Sense and Reference (1892), which Frege is careful to frame, not in terms of the semantics of his logical language, but in terms of the “cognitive value” of the statements under discussion, the paradox of imprecision in language is not really about language itself, but about the intuitions of language users, and is therefore a philosophical problem. Obviously, an expression of natural language is either well-formed or not, and, considered in itself, can only be alleged to be imprecise relative to its own semantics, i.e. not well-formed, since the semantics of a language is internal to the language, able to be formalized entirely in linguistic terms. Therefore, the analysis focuses on cases of syntactic deviance and semantic ambiguity in which the imprecision is in principle not soluble by the language user by reference to the recursive rules of his language. If he acquires the correct cognitive content from the expression, then on what grounds is the expression alleged to be imprecise? And if the expression is not in fact imprecise, then how does the language user get the intuition that it is?
Examples of the phenomenon of efficient imprecision are drawn from ordinary colloquial speech and also from slang expressions, whose function and development this analysis may help to explain. After analyzing this apparent paradox, the paper concludes by briefly sketching some possible consequences bearing on broader philosophical topics of questions raised in the course of the analysis; in particular, that the process of acquiring information from such expressions, with which our everyday language is filled, may in fact be the central activity involved in Wittgenstein’s concept of the language-game, and that the tacit and widespread assumption among philosophers of language that human language is either a high-resolution inner “picture of the world” or a meaningless “game” is likely a fundamental fallacy
Bacterial Bio-transformation to Optimize Catechin's Insulin Sensitivity
No full textSustainable IndustryInsulin is a hormone produced by the body that helps humans process and store glucose. People with Type 2 Diabetes suffer from their cells lacking insulin sensitivity, causing them to not process it accordingly. The loss of control over glucose production and storage leads to a hyperglycemic state which leads to the symptoms of diabetes. Unfortunately, anti-diabetic medications often have negative side effects. Preliminary work has shown that catechols can increase cellular sensitivity towards insulin, and could possibly be a nutraceutical therapy for diabetes. Catechol is not found free in many foods, but its precursor, catechin, is present in many natural sources, such as blueberries, berry juices, and green tea, and has exhibited anti-diabetic effects on cultured cells. Lactobacillus, gut bacteria found in yoghurt, has been shown to transform catechin into catechols through prior research, but not proven in all types of the bacteria. Based on previous literature, we have analyzed bacterial processes that can help moderate insulin sensitivity. Bacterial metabolism of catechin produces catechol, either as an intermediate or end product. This presentation will discuss progress in our lab towards identifying and developing a Lactobacillus strain that can effectively convert catechin into catechol. The underlying biology, analytical chemistry, and our preliminary microbiology results will be discussed on how our work is expanding on previous literature and its methods