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Exploring SDG 16: Peace, Justice, and Strong Institutions
No full text['UNSDG 16: Peace, Justice and Strong Institutions (https://sdgs.un.org/goals/goal16)']Viable, Healthy and Safe CommunitiesPeace, justice, and strong institutions are the foundation of a stable and prosperous society. They support a sense of safety and trust in the government and its institution while making sure that everyone is treated fairly and has access to equal opportunities. An effective legal system that upholds justice and works to prevent crime encourages economic development and investment. Society needs to make changes in order to maintain stability and peace because, without change, society is likely to become stagnant, inequitable, and prone to conflict. The University of Windsor aims to promote SDG 16 through research and extracurriculars around campus. For example, targets 16.3, promoting the rule of law and ensuring equal access to justice; 16.6, developing effective, accountable and transparent institutions; and 16.B, promoting and enforcing non-discriminatory laws and policies are addressed through Brandon Chase's master thesis Peace Bonds as Counter-Law. Stable and open institutions attract investment and generate employment. For the protection of human rights and the advancement of social cohesion, a peaceful society with an equitable and functional judicial system is necessary. In other words, creating a society that is free, equitable, and wealthy for all requires peace, justice, and strong institutions. Sustainable Development Goals, or SDGs, are used to accomplish objectives all around the world. The sixteenth SDG will be covered in this talk. As it focuses on peace, justice, and robust institutions, SDG 16 encourages creating a cooperative and peaceful society. By embracing change and making necessary adjustments, societies can foster stability and peace, reducing the risk of conflict and creating a more harmonious world for all
Survivor Guilt Related to Transplant Recipients: A Concept Analysis
No full textSurvivor Guilt Related to Organ Transplant Recipients: A Concept Analysis A concept analysis of survivor guilt (SG) related to organ transplant recipients was conducted to provide a clear description of this distressing phenomenon. Whether transplant recipients receive a cadaveric or living organ donation, there is inherent harm to the donor whereby the recipient may feel emotional anguish. Despite the hope of a second chance at life, SG can cause mental and/or physical symptoms such as depression, chronic anxiety, and insomnia. SG can lead to negative coping behaviours such as non-adherence to the post transplant regimen, avoidance behaviours or even self-harm, which may result in allograft rejection. Walker & Avant's eight-step concept analysis method was used to clarify the meaning of SG in relation to organ transplant recipients. The data sources for the electronic literature search included CINAHL, PubMed, and PsycINFO. Dictionary definitions, Google Scholar and related reference lists were also utilized. Four determining attributes of SG are: being saved from harm, the presence of loss or harm for someone else, self-perceived responsibility for the loss or harm, and emotional anguish. Advancing knowledge about the conceptual definition of SG related to transplant recipients empowers nurses, patients, and caregivers to assess and identify SG: the first steps toward better care. By exploring and understanding SG, we can help organ recipients and their families survive SG, thus contributing toward building healthy and safe communities for all
Towards the synthesis of an acetal-free TF antigen from glucosamine
No full textUWill Discover 2018 Abstract Asma Ghafoor, Iraj Sadraei, John F. Trant Towards the synthesis of an acetal-free TF antigen from glucosamine Carbohydrates make up many of the key molecules in our body, especially those involved in signaling, and these systems are of growing interest in regard to better understanding and treating diseases. Carbohydrates are increasingly being found to play an important role in the immunogenic responses to different microbial infections and even to cancer. In terms of cancers, certain carbohydrates have been found to be expressed only on the surface of carcinomas: they are not found on healthy cells. The TF antigen, a simple disaccharide, is one such marker and is found on >85% of all carcinomas regardless of organ (ie breast, ovarian, cervical, prostate, lung, liver etc.); however, the immune system is not good at identifying carbohydrates. Consequently, we need to design new synthetic vaccines to draw attention to these targets so that the body can initiate an immune response to kill the cancer., Unfortunately, the highly biodegradable nature of carbohydrates, when exposed to various pH conditions and enzymes in the body, make it difficult to use carbohydrates in vivo. As a result, extensive and complex syntheses must be carried out to create disaccharides with better enzymatic resistance, so that they can exist long enough to initiate the immune response. The Trant Team hopes to create more stable carbohydrates by removing the unstable acetal group by replacing the exo-cyclic oxygen with a methylene group; this class of materials are known as C-glycosides. This presentation will explore our approach of using glucosamine as a starting product to produce this challenging target, and describe the potential application of this technology towards cancer therapy
The Sensible Reason
Get PDFThis thesis introduces an innovative perspective, suggesting that sensible reasoning in argumentation is a process that imparts meaning and coherence to what is expressed, explaining both the argumentative levels and the process of persuasion within argumentation. The relevance of this contribution lies in its unique analysis, through which it becomes possible to speak of sensible reasons and understand, from the concept of the argumentative situation, how this reasoning operates for all involved at that moment. Sensible reasoning encompasses a logic that, while reasonable, is better interpreted through an aesthetic framework that addresses its perceptual and affective nature. Thus, this research underscores that emotions are not merely a complement in decision-making but an essential component that significantly contributes to the argumentative process. Traditionally, Argumentation theory has prioritized logical reasoning; however, this work demonstrates how people reach conclusions through a combination of sensible reasons, allowing for a more comprehensive and nuanced understanding of human reasoning. In this context, sensible reasons are presented as a valid form of understanding and evidence within the argumentative process, enlightening the audience about the complexity of human reasoning. The theoretical framework of this dissertation is based on Pablo Fernández Christlieb's theory of Collective Affectivity, which proposes that emotions can be understood from an aesthetic and cultural perspective. From this approach, which conceives emotions as social and collective elements, this dissertation argues that emotions influence individual perception and are also an integral part of argumentative processes, as argumentation is a cultural, collective, and sensible construct. By addressing emotions from an aesthetic logic, their capacity to structure and provide coherence to arguments is recognized, challenging traditional notions that perceive them as irrational or secondary. This dissertation argues that emotions provide both coherence and reasonableness to arguments. They function from their own affective logic and contribute to the formation of conclusions that integrate the sensible and the rational. In Chapter I, an exhaustive analysis is conducted on how emotions have historically been treated in Argumentation theory. Drawing on the contributions of thinkers such as Antonio Damasio and Robert Solomon, it is argued that emotions possess an internal logic that can be analyzed and evaluated, and that their role in decision-making has been underestimated. This chapter also introduces the concept of sensible reason, a type of reasoning deeply influenced by emotions, where the world is understood and explained through what is felt. Chapter II explores the role of aesthetics as an epistemological framework for understanding sensible knowledge. It examines how aesthetic and sensible forms influence the perception and reception of arguments and how emotions and sensible perceptions can provide evidence and meaning to argumentative processes. Through the analysis of artistic and cultural forms, it is shown how sensible knowledge contributes to the formation of meaning in argumentation. Chapter III introduces the concept of the argumentative situation, which refers to the context in which the argumentative process occurs and how emotions and sensible forms influence the reception of arguments. This chapter demonstrates how emotions play a crucial role in the persuasive effectiveness of arguments, especially in situations where formal logic alone is insufficient to capture the full depth of human reasoning. Chapter IV presents a case study on the Zapatista Army of National Liberation (EZLN) in Mexico, exemplifying how a political movement can employ collective emotions, such as dignified rage, to structure its political discourse. The analysis of EZLN's speeches and narratives shows how emotions, articulated through cultural symbols and sensible forms, provide coherence and legitimacy to its political argumentation. This case study highlights how emotions and aesthetic elements are fundamental to the persuasive power of the EZLN's discourse. In conclusion, this dissertation significantly contributes to the field of Argumentation theory by proposing an integration of aesthetics and emotions in the analysis of reasoning and persuasion. By demonstrating that emotions are neither irrational nor merely complementary but essential to constructing and evaluating arguments, this research offers an innovative theoretical framework that allows for a broader and more complex understanding of human reasoning. Furthermore, it provides a practical approach that can be applied in various political and social contexts, offering a new way to understand how sensible forms influence argumentative processes
Canadian Muslim Excellence: A Time to Celebrate, Educate, and Reflect
No full textThis podcast examines the increased incidents of Islamophobia in Canada and the impact of Islamophobia on Muslim Canadians. The overall project being presented seeks to bring attention to the need for intentional strategies embedded in education to help combat Islamophobia. A specific strategy of explicitly celebrating and highlighting Canadian Muslim Excellence is outlined. Sharing the stories of Muslim Canadians that have had a positive impact on our country, is intended to increase the positive messaging surrounding some of the wonderful contributions that Muslim Canadians have accomplished. This podcast also speaks to strategies in place to assist educators in continuing the work of dismantling the stereotypes and fear that come with Islamophobia. Providing the listener with resources to share the names of Muslim Canadians to be celebrated, accompanied by their memorable stories and newly developed lesson plans for the classroom, this project aims to increase the positive portrayal of Muslim Canadians and decrease the display of negative stereotypes and acts of hatred. Canada would not be the same if it were not for our diversity. We need to be intentional in celebrating, educating, and reflecting in ways that work to combat hatred
Green Behaviors in the Laboratory, Environmental Donations in the Field
Get PDFBehavior within an experiment is generally explained by either a pure profit motive or a response to the context of the experiment which is likely driven by different factors such as individuals' environmental friendliness. Are participants in laboratory experiments responding to the context of the experimental setting and not merely to a profit motive? Using a preliminary analysis, I draw evidence from data collected in a two-stage laboratory experiment designed and conducted by Palm-Forster et al. (In Press) at the University of Delaware. In the first stage of the experiment, participants performed a series of tasks concerning their tradeoffs between monetary profits and environmental friendliness. In the second stage, participants made a choice of donating to a large environmental organization. In total, 156 undergraduate students participated in the experiment. The analysis in this paper provides preliminary results that need to be verified in future research after overcoming key model specification issues
Provincial Cannabis Legislation, Regulation, and Licensing: Its Effectiveness and Impacts on Municipalities in Ontario
Get PDFThe legalization of cannabis has been a controversial topic within the last two decades in many developed states. The legalization brought medicinal benefits, economic opportunity, and a projected decrease in organized crime. It has, however, also prompted new challenges for different levels of government. In Canada, legalization was a federal decision that was then regulated by provincial governments. However, local governments were on the receiving end of both federal and provincial legislation and regulations that often restricted municipal autonomy with respect to cannabis. This paper aims to provide a better understanding of the legal and regulatory framework of retail cannabis in Ontario and to contribute to other long-term studies with respect to this matter. Through case studies of the Town of Tecumseh and the Municipality of Lakeshore, it focuses on dissecting the role of municipal governments in the Canadian example of cannabis legalization and regulation. It finds that the downloading of federal policy and provincial regulation has kept municipalities in a subservient state
A Warmer, Green Golden Rule
Get PDFThe goal of this paper is to analyse the impact of temperature changes on the green golden rule. The green golden rule is the maximization of consumer utility based on consumer preference between consumption and environmental stock. The trade-off between environmental stock and consumption which is found to be negative. With temperature change being very prevalent in our era, we look at temperature change in the form of a damage function. By looking at both an increasing and decreasing damage function, along with changing variables in the green golden rule, we see that when the average global temperature deviates from the mean, be it above or below the mean, there is a decrease or increase in the damage function respectively
The Windsor/Detroit Border Region: A Transnational Jazz Community (1940s & 1950s)
No full textUnderstanding BordersABSTRACT: The 1950s have been called the "golden age of jazz in Detroit" on account of the role Detroit jazz musicians played in the development of the hard bop style. This sub-genre a synthesis of R&B, gospel and blues elements with the traditional bop style became very popular in the 1950s and quickly spread across America. Scholarship in recent years has examined Detroit's contribution to the development of jazz, but its smaller Canadian counterpart, Windsor, has largely been ignored. The presence of an urban border facilitated a considerable amount of cultural exchange between the two cities, and cross-border advertising campaigns suggest that jazz clubs on either side of the border were attracting international audiences. This project examines the implications of the unique cultural dynamic in the Windsor-Detroit border region and tracks the development of a transnational jazz community in the 1940s and 1950s. Using GIS software, a map of relevant jazz performance venues (i.e. jazz bars, concert halls) was created to better visualize the concentration of the jazz community on both sides of the border. This study of important cultural hubs, a culmination of previous research, archival work, and interviews with local musicians – suggests that the Windsor jazz community developed as a product of the growing influences and pressures from the booming jazz scene in Detroit and grew dependent on American customers. Other issues of Americanization, cultural appropriation, and the cross-border economy are also discussed. Studying these unique relationships between transnational jazz communities generates interesting applications to multi-disciplinary work relating to understanding borders and their socio-economic impact. KEYWORDS: Borderlands, Jazz, Windsor-Detroit, Borders, GIS Software, Digital History, Musicolog
Toward the synthesis of an acetal-free Tn antigen anti-cancer vaccine candidate
Get PDFCancer vaccines are a promising approach to cancer treatment by activating the immune system towards cancer cells. The challenge, however, comes with the identification of biomarkers correlated with cancer. Unfortunately, many oncotargets are simply upregulated in cancer; these are inappropriate vaccine targets as they are also present on healthy cells and therefore would ultimately initiate a very dangerous systemic immune response. In contrast, Tumor-Associated Carbohydrate Antigens (TACAs) are not found in healthy adult tissue but are found on over 90% of biopsied carcinomas. When incorporated into glycopeptides or other immunogenic scaffolds, these carbohydrate antigens have formed the basis of the development of anti-tumor immunotherapies through the induction of a specific immune response against cancer cells. However, despite promising preliminary data, none of these candidates have reached the clinic. Our hypothesis is that the carbohydrates on the vaccines may not survive antigen processing, and so more stable versions of these materials are required to create viable vaccines. Our approach is to incorporate TACAs lacking the labile glycosidic bond: acetal-free carbohydrates (AFCs). This project aims to remove the unstable acetal functional group to yield a more robust carbohydrate structure that can then be incorporated into a vaccine candidate. In this presentation, two synthetic pathways will be described: conversion of a carbohydrate to a carbasugar through a rearrangement, and de novo synthesis from noncarbohydrate materials