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    Evaluation of the standardization of platelet-rich plasma protocols and composition in treatment of knee osteoarthritis: a systematic review

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    This project sought to determine if there has been an improvement in the number of studies that have reported on PRP preparation metrics and protocol since 2017 A systematic review of the literature published from 2017 to 2023 was conducted using PubMed/Medline database. Inclusion criteria were human clinical trials, English-language literature, and articles that investigated the effect of PRP injections in knee osteoarthritis

    Artificial intelligence and equitable healthcare delivery: a narrative review

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    An exploration of the current relationship between artificial intelligence and the equitable delivery of healthcare. Discusses capacity to enhance bias, improve equitable delivery, and unique circumstances of the relationship

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    Improving employee safety in an outpatient psychiatric private practice via de-escalation training: a quality improvement project

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    This quality improvement project sought to improve employee confidence in coping with patient aggression in an outpatient psychiatric private practice via de-escalation training. Training consisted of a 50-minute didactic presentation facilitated by a content expert that utilized original training materials informed by Richmond’s 10 Domains of De-escalation (2012) and the content expert’s experience in the field. The specific aim was to improve knowledge and comfort by 15% following the intervention. This aim was met by an average 50.41% increase in knowledge and 15.9% increase in comfort reported by in-person attendants (N=9). It further indicated a need for education of best practice self-defensive strategies to improve feelings of safety during an incident. These results suggest that providing de-escalation training to private practice employees may lead to improved levels of confidence when navigating instances of patient aggression

    Improving trauma-informed care for pediatric nurses

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    Trauma secondary to abuse and neglect is prevalent among the pediatric population, especially among children younger than 4 years old and those with disabilities. Trauma-Informed Care (TIC) is one way to help mitigate the effects of trauma and prevent further psychological damage, yet many providers are not confident in how to implement TIC. The aim of this project is to increase TIC knowledge and confidence scores among pediatric providers

    TB and the sphinx: an investigation into the ways host sphingolipids affect mycobacterium tuberculosis infection

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    Tuberculosis (TB) is a devastating illness. In the search for novel anti-TB therapies, there is growing interest in host-directed therapy (HDT), which seeks to synergize with frontline antibiotics by altering the host conditions – making us a less hospitable host – and re-sensitizing the bacteria to antibiotic therapy. This dissertation project lies at the intersection between two understudied fields: host-pathogen interactions and sphingolipids during Mycobacterium tuberculosis infection

    Time to antibiotic administration for neutropenic fever in the emergency department

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    Neutropenic fever, a common complication in cancer patients, requires prompt antibiotic treatment to prevent mortality. Current guidelines recommend antibiotic administration within 60 minutes of triage completion. However, many emergency departments (EDs) struggle to meet recommended treatment timeframes. This study in an academic medical center's ED analyzed 88 neutropenic fever cases, revealing a median time to antibiotic administration of 146 minutes, with only 7.95% meeting the 60-minute guideline. Factors like door-to-doctor time, time to antibiotic order placement, and antibiotic preparation time were found to affect time to antibiotic administration. No correlations were found between time to antibiotic administration and long-term patient outcomes in this study. Future initiatives should focus on reducing time from triage completion to antibiotic order placement to optimize patient outcomes and improve care for neutropenic fever patients in the ED

    Developing patient and family feedback surveys at an urban pediatric gender care center

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    With the rapid expansion of pediatric transgender and gender diverse (TGD) healthcare, the need for standardized feedback mechanisms has become evident. This study addresses this need by developing patient and family surveys for a gender care clinic (GCC) in the Pacific Northwestern United States. The study purpose was to assess patient and caregiver satisfaction and identify areas for improvement within the TGD clinic

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