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Political Uncertainty in the Behavior of Rental Housing Prices in Spain. Time Trends and Persistence Analysis
Full text linkOver time, Spain has implemented various legislative measures to address the imbalance between homeownership and rental housing in a real estate market closely linked to the country's economic conditions. Changes in governance have introduced different regulatory approaches that may have influenced rental prices. This study examines the relationship between political uncertainty and rental housing prices in Spain from 1997 to 2024, using fractional integration, fractional cointegration, and wavelet analysis. The results indicate that exogenous shocks, such as uncertainty, temporarily affect rental prices. Additionally, a one-point increase in the Economic Policy Uncertainty index correlates with a 16.4-point rise in rental prices.Empres
Aurora kinase A drives non-canonical YAP1/TAZ crosstalk to sustain primary resistance to anti-EGFR therapies in colorectal cancer
Full text linkAnti-epidermal growth factor receptor (EGFR) therapies are the most recommended first-line treatment for RAS/RAF wild-type unresectable metastatic colorectal cancer (CRC) according to the European Society for Medical Oncology guidelines. However, primary resistance renders this treatment ineffective for almost 40% of patients. Our previous work identified Aurora kinase A (AURKA) as a key resistance driver through non-canonical, Hippo-independent Yes-associated protein 1 (YAP1) activation. However, the role of the other main Hippo coactivator, transcriptional coactivator with PDZ-binding motif (TAZ), in this resistance mechanism remains unexplored. By integrating preclinical in vitro and in vivo models, including cell lines and patient-derived xenografts, with RNA sequencing, we investigated the impact of TAZ overexpression in cetuximab resistance driven by the AURKA/YAP1 axis. Our findings reveal that TAZ overexpression sustains YAP1-mediated resistance and stemness. Even under YAP1 suppression, TAZ-overexpressing cells remain unresponsive to anti-EGFR therapies, whereas dual YAP1/TAZ silencing restores sensitivity. Treatment with alisertib, a phase III AURKA inhibitor, simultaneously destabilizes YAP1 and TAZ, restoring anti-EGFR efficacy by suppressing stemness. Transcriptomic analyses further show that AURKA inhibition and dual YAP1/TAZ suppression disrupt stem-like traits and reveal transcriptional deregulations affecting nucleotide metabolism. These findings demonstrate that AURKA orchestrates YAP1/TAZ crosstalk, which is crucial for driving stemness and resistance to anti-EGFR therapies, highlighting AURKA inhibitors as a promising strategy to enhance anti-EGFR therapies in metastatic CRC.Psicología y Ciencias de la Salu
Lola Rivas Cherif: la mujer fuerte del presidente de la República
No full textA lo largo de la historia, algunos personajes de relevancia han permanecido en un discreto segundo plano. Este es el caso de Lola Rivas Cherif (1904-1993), una mujer que, desde la sombra, encarnó los valores de la República y fue un pilar fundamental en la vida de Manuel Azaña, tanto en lo personal como en lo ideológico. Junto a su marido, vivió acontecimientos históricos trascendentales: la proclamación de la II República, la sublevación militar y la posterior guerra civil, y el peor de los episodios, el exilio a una Francia ocupada por los nazis. Tras la muerte de Azaña, se exilió en México donde falleció cuarenta y dos años después. Su actitud siempre estuvo marcada por la reconciliación. Aunque el dolor fue una constante en su vida, nunca expresó odio ni rencor. Azaña la describió como mujer fuerte y no se equivocaba. Fue la sombra y el soporte de don Manuel. La mujer que un estadista necesitaba a su lado. Además, la historia le hace justicia por su labor en el cuidado y la difusión de las obras de Azaña. Lola Rivas Cherif, requería una biografía que visibilizara a la mujer del presidente de la II República Española.Humanidade
The Metrics of the DMA’s Success
Full text linkThe Digital Markets Act (DMA) is a rare bird in competition policy. Indeed, it is a hybrid framework incorporating the institutional setting of a regulatory tool as well as the conduct already targeted by antitrust authorities in proceedings against digital platforms. From a policy perspective, the DMA seeks to prevent some anticompetitive practices. To this end, the EU legislator has construed an intricate set of provisions pursuing different policy goals. After setting out these goals in relation to the proclaimed legal interests protected by the DMA (ie, contestability and fairness), the paper uncovers the policy goals underlying each of the provisions. Relying on the first round of compliance reports issued by gatekeepers in March and October 2024, the analysis aims at providing adequate pathways to measure the DMA’s success, based on the explicit legal interests and implict policy goals fleshed out by the regulation. The paper maps out market scenarios where policymakers can assert that the DMA’s enforcement has been effective.Ciencias Jurídica
Key Competences That Allow Excellence in Teaching Practice
Full text linkThe Europe 2020 Education Principles emphasize the improvement of educational
processes at all levels, aiming to enhance educational standards through the integration of personal and professional competences with teaching skills. This study focuses on the validation of a new tool for assessing teaching competences, which aims to support excellence in teaching practice. Using Confirmatory Factor Analysis (CFA), the study provides evidence for the multidimensional nature of
teacher self-efficacy, supporting a four-factor model consisting of reciprocal leadership, creative potential with institutional support, didactic technical domain and active personality with metacognitive didactic capacity. Internal consistency was assessed using Cronbach´s Alpha, and the estimation method employed was Weighted Least Squares Means and Variance Adjusted (WLSMV), following
recommendations of Hu & Bentler (1999), such as a GFI and TLI value of at least .90 and RMSEA of .08 or less. The study demonstrated good psychometric properties, supporting the use of this tool to evaluate teaching competences in real world contexts. These findings contribute to the field by linking teaching
competences to the notion of complementarity and coexistence, fostering sustainable education and aligning with the principles of democratic teaching.Educació
Fuentes dramáticas susceptibles de influir en el cine biográfico español del primer franquismo: visión panorámica y estudio bibliográfico
Full text linkDurante el primer franquismo se incrementó la
producción de películas histórico-biográficas
en comparación con el período republicano.
Aunque solo un número reducido de ellas
supuso la adaptación directa de un drama
histórico, cabe preguntarse si para las
películas restantes había fuentes dramáticas
de temática similar, que ya habían retratado
al personaje histórico protagonista. En
el marco de los estudios de la literatura
comparada, y atendiendo especialmente al
análisis textual, esta investigación propone
una visión panorámica de las relaciones entre
el cine biográfico del primer franquismo y los
géneros teatrales (dramas históricos, comedias
y zarzuelas). Con este propósito, establecemos
una lista de las fuentes dramáticas susceptibles
de haber influido en cada película biográfica
de la posguerra. Mediante un breve estudio
comparativo de cada caso, analizamos si alguna
de esas fuentes teatrales previas del período
barroco, romántico o regeneracionista pudo
influir en cada filme. Llegamos a la conclusión
de que, en determinados casos, hubo escenas,
diálogos y situaciones directamente extraídos
de una obra teatral previa, así como similitudes
narrativas argumentales y de estructura.
También se observa cómo, en el caso de algunDuring the early Franco regime, the production of historical-biographical films
increased in comparison with the Republican period. Although only a small number
of them involved the direct adaptation of a historical drama, it is worth asking
whether for the remaining films there were dramatic sources of similar subject matter,
which had already portrayed the main historical character. Within the framework
of comparative literature studies, and paying special attention to textual analysis,
this research proposes a panoramic view of the relations between the biographical
cinema of the early Franco regime and theatrical genres (historical dramas, comedies
and zarzuelas). To this end, we establish a list of the dramatic sources likely to have
influenced each post-war biographical film. By means of a brief comparative study of
each case, we analyse whether any of these earlier theatrical sources from the baroque,
romantic or regenerationist period could have influenced each film. We conclude
that, in certain cases, there were scenes, dialogues and situations directly taken from
a previous play, as well as narrative similarities in plot and structure. We also observe
how, in the case of some direct adaptations, excessive adherence to the dramatic text
caused rigidity in the narrative and fell out of favour with audiences, while innovation
in filmmaking, while maintaining fidelity to the text, resulted in better box-office
performanceComunicació
Integrating Personal Growth in ADE Curriculum for Sustainable Impact
Full text linkThis conceptual study addresses the integration of intra-personal skills into Spanish business (ADE) curricula to meet sustainability challenges and impact investment demands. The research proposes a three-dimensional framework connecting (1) intra-personal competency development, (2) sustainability knowledge domains, and (3) pedagogical implementation strategies. Our analysis reveals implicit elements of introspection in current curricula but identifies a significant gap in structured approaches to intra-personal skill development. Successful integration requires comprehensive institutional support across multiple levels. This study reconceptualizes business education beyond technical competencies, offering educational practitioners a practical roadmap for curriculum redesign that develops the reflective capacities needed for responsible business leadership in sustainability contexts.Empres
Desvelando a la persona humana: la propuesta epistemológica de Leonardo Polo para una antropología trascendental
Full text linkSe pueden observar dos revoluciones centrales en la historia de la filosofía. La primera, cuando Aristóteles formalizó el lenguaje filosófico y la metafísica. La segunda, cuando los filósofos modernos centraron su atención en el sujeto cognoscente. El proyecto moderno está estancado debido a la insuficiencia de las nociones antropológicas clásicas para dar respuestas a cuestiones clave como la naturaleza y el alcance del conocimiento humano, la libertad y las relaciones interpersonales. L. Polo propone una teoría del conocimiento que aporta las piezas que faltaban, permitiéndole desarrollar una antropología trascendental que completa el retrato de la persona humana.There have been two major revolutionsin the history of philosophy. The first, when Aristo-tle formalized philosophical language and me-taphysics. The second, when modern philosophersturned to the thinking subject. The modern projectis stalled due to the inability of classical anthropolo-gical notions to provide answers to key questions,like the nature and scope of human knowledge,freedom, and interpersonal relations. L. Polo pro-poses a theory of knowledge that adds the missinglinks, enabling him to develop a fully-fledged trans-cendental anthropology that completes the pictureof the human personHumanidade
Democracia, ciudadanía y justicia. Una reflexión integral
Full text linkEl artículo analiza los retos de la justicia en las democracias contemporáneas, destacando su papel como garante de derechos fundamentales y promotora de cohesión social. Se señala el aumento de la litigiosidad, la juridificación de la sociedad y la desafección ciudadana como problemas centrales que afectan la eficiencia y la confianza en el sistema judicial. Se proponen reformas estructurales como la simplificación de procedimientos, el fortalecimiento de los mecanismos alternativos de resolución de conflictos y la incorporación de tecnologías digitales de manera ética y eficiente. También se resalta la importancia de la justicia de proximidad para mejorar el acceso ciudadano y reducir la percepción de alejamiento institucional. Se subraya que la justicia debe abordar tanto las desigualdades materiales como las simbólicas, consolidándose como un proceso continuo y participativo que refuerce los valores democráticos y garantice la equidad.The article analyzes the challenges faced by justice in contemporary democracies, highlighting its role as a guarantor of fundamental rights and a promoter of social cohesion. It points out the increase in litigation, the juridification of society, and citizen disenchantment as central issues affecting the efficiency and trust in the judicial system. Structural reforms are proposed, such as the simplification of procedures, strengthening alternative dispute resolution mechanisms, and incorporating digital technologies in an ethical and efficient manner. The importance of proximity justice is also emphasized as a way to improve citizen access and reduce the perception of institutional remoteness. It is underscored that justice must address both material and symbolic inequalities, establishing itself as a continuous and participatory process that reinforces democratic values and ensures equity.Ciencias Jurídica
Does talking about advertising make me recognize it better? Incidence of parental and social mediation on the advertising literacy of the Alpha generation
Full text linkIntroducción: El trabajo que aquí se presenta, aborda cómo los niños de 7 a 10 años, pertenecientes a la Generación Alpha, perciben y gestionan los contenidos publicitarios a los que están expuestos en entornos digitales. Además, se centra en analizar cómo las interacciones con sus padres o tutores y amigos influyen en su capacidad para reconocer formatos persuasivos y su percepción de control sobre la publicidad. Metodología: Esta investigación utiliza una metodología cuantitativa con una muestra de 1.304 niños en España, aplicando un cuestionario que mide el conocimiento sobre publicidad, la capacidad para reconocerla y el grado de mediación parental y social. Resultados: Los resultados reflejan que los niños que conversan sobre publicidad con sus padres tienen una mejor comprensión del fenómeno publicitario y se sienten más capaces de identificar los anuncios. Sin embargo, las conversaciones con amigos, aunque relevantes, tienen menor impacto. Además, los menores perciben mayor control sobre la publicidad digital cuando tienen un mayor conocimiento sobre esta. En definitiva, las conversaciones con los padres sobre publicidad no solo aumentan la percepción del conocimiento que los menores tienen sobre la publicidad, sino que también refuerzan su confianza en la capacidad de identificar contenidos publicitarios. Discusión: Una de las principales conclusiones de este trabajo indica que la mediación parental es clave para la alfabetización publicitaria de los menores, mientras que la mediación social complementa este proceso. Conclusiones: Estos hallazgos subrayan la necesidad de diseñar programas educativos que involucren a los padres en la alfabetización publicitaria, fomentando un entorno que promueva conversaciones enriquecedoras sobre la publicidad.Introduction:The research presented here addresses how children aged 7-10, belonging to Generation Alpha, perceive and manage the advertising content they are exposed to in digital environments. In addition, it focuses on analyzing how interactions with their parents/guardians and friends influence their ability to recognize persuasive formats and their perceived control over advertising. Methodology:This research uses a quantitative methodology with a sample of 1,304 children in Spain, applying a questionnaire that measures knowledge about advertising, the ability to recognize it and the degree of parental and social mediation. Results: The results show that children who discuss advertising with their parents have a better understanding of the advertising phenomenon and feel more able to identify advertisements. However, conversations with friends, although relevant, have less impact. In addition, children perceive greater control over digital advertising when they are more knowledgeable about it. In the end, conversations with parents about advertising not only increase children's perceived knowledge of advertising, but also reinforce their confidence in their ability to identify advertising content. Discussion: One of the main conclusions of this work indicates that parental mediation is key to children's advertising literacy, while social mediation complements this process. Conclusions: These findings underline the need to design educational programs that involve parents in advertising literacy, fostering an environment that promotes enriching conversations about advertisingComunicació