RODBUK Jagiellonian University in Kraków
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    737 research outputs found

    Mazur A "Neutrophils from patients with acquired neutropenia exhibit alterations in serine protease immunostaining and activity" - raw data

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    Data sets contaning flow cytometry files documenting patients neutropenia as well as Excel files containing raw data supporting Fig 1 and Fig2

    Plasma-Enhanced Magnetic Transition in 3D Mn(II)–Nb(IV) Octacyanidometalate Magnetic Sponge - research data

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    This data set comprises the results related to investigating the influence of plasma treatment on the magneto-structural properties of the studied compound. It includes the following measurements: 1. X-ray powder diffraction patterns. 2. Scanning electron microscopy images. 3. X-ray absorption spectra. 4. Magnetization and magnetic susceptibility data. 5. Thermogravimetric analysis. 6. Dynamic vapor sorption data

    The Hypoxic Microenvironment of Candida albicans Biofilms Shapes Neutrophil Responses - raw data

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    The dataset contains raw and processed data collected during the NCN PRELUDIUM 21 research project and underlying the publication "The Hypoxic Microenvironment of Candida albicans Biofilms Shapes Neutrophil Responses". The dataset includes confocal and fluorescence microscopy images of neutrophil-biofilm interactions, as well as quantitative analyses of neutrophil activity at different biofilm maturation stages. The data were obtained from biological replicates and are provided in their original formats to ensure reproducibility

    The Raman Map of the Human Cell - research data

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    This dataset contains Raman spectra of subcellular compartments and reference compounds of selected biomolecules

    Hypoxia as a driver of morphological and molecular microevolution of pancreatic ductal adenocarcinoma cells and spheroids - replication data

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    The dataset was generated to investigate the phenotypic evolution and tumorigenic potential of pancreatic ductal adenocarcinoma (PDAC) cells under normoxic and hypoxic conditions. By integrating machine learning-assisted image analysis, the study aimed to quantify morphometric changes in 2D cultures and assess molecular and cellular adaptations, with a focus on epithelial-mesenchymal transition (EMT) and tumor microevolution. The dataset includes: (A) quantitative morphometric data of 2D and 3D cells in normoxia and hypoxia (e.g., spheroid size, shape, density, and circularity); (B) molecular marker expression levels associated with hypoxia response (VHL), fibrosis (Col1, elastin), and EMT (vimentin, β-catenin, N-cadherin); (C) kinetics of tumor in murine model highlighting their tumorigenic potential. The dataset provides comprehensive insights into hypoxia-driven adaptations in PDAC cells, covering: (A) cellular and spheroid-level responses to oxygen deprivation; (B) lineage-specific differences in hypoxia adaptation between PAN_02 and PANC-1 cells; (C) machine learning-assisted multi-parametric quantification of PDAC plasticity and microevolution

    Hydrogel-Based Implantable System for Local Delivery of Temozolomide in Postsurgical Brain Cancer Therapy - research data

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    Data generated during studies on the hydrogel-based implantable system for local delivery of temozolomide are provided. The raw experimental dataset consists of the physicochemical evaluation of developed hydrogel-based systems (the degradation, gel fraction and swelling experiments). In addition, data from model drug release experiments performed under physiological conditions are presented. Moreover the selected dataset regarding the biological evaluation in vitro was also provided. Human polymorphonuclear neutrophils were analyzed for the formation of neutrophil extracellular traps (NETs) using fluorescence microscopy. Microscopy images were captured using a fluorescence microscope (Olympus IX83) at a magnification of 40x. The following fluorescent markers were used: DAPI (cell nuclei) and Alexa Fluor 546 (myeloperoxidase). Exposure settings and laser intensities were consistent across all samples. The images were processed for noise reduction and contrast enhancement. The raw images were processed using ImageJ (1.54f) software. The fluorescence range was standardized across all images, and signal intensity was normalized. The files were saved in TIFF format to preserve high resolution. TIFF file names follow the convention: type of material_temozolomide grafting_ time point of extract collection (e.g. 541_Ctr_4h) Excel files were exported from the LEGENDplex™ software (BioLegend, USA). Calculations in the LEGENDplex™ software were performed according to the default settings (the gating strategy was based on the LEGENDplex™ software algorithm, without any changes made by the data analysis personnel). Excel file names follow the convention: species_cell type_report_date of report export (e.g. Human_hPMN_hPBMC_report_2024-11-26

    Ultra-Dense, Highly Ordered and Thermally Stable Anthracene Monolayers on Ag(111)The Impact of the Anchoring Group - replication data

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    Replication data for publication "Ultra-Dense, Highly Ordered and Thermally Stable Anthracene Monolayers on Ag(111)The Impact of the Anchoring Group

    Expression of NKA and ammonia transporters during CEV and CyHV-3 infection of common carp

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    Data from the project founded by NCN in the frame of Beethoven Life 1 call. Project title: Impact of virus-induced gill disease caused by carp edema virus (CEV) on the immunological status of fish

    Structural Characterization of Co₃O₄@meso-SiO₂ Nanoreactors Using Multiple Techniques ( XRD, XRF, UV-Vis DR, FTIR, XPS, H2-TPR, SEM, TEM)

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    The dataset included in this depository is composed of data that were used to publish the scientific paper entitled: Polymer template assisted construction of spherical Co3O4@meso-SiO2 yolk-shell nanoreactors for catalytic combustion of volatile organic compounds

    Interview Transcripts - Social Determinants of Prosumerism in Polish Rural Households

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    This dataset contains 17 transcripts of semi-structured qualitative interviews examining how gender and social status shape household decision-making regarding renewable energy adoption in rural Poland. Data were collected during January-February 2025 in a rural municipality in southern Poland as part of a Master's thesis research project. Participants were recruited through purposive and snowball sampling, including households both with and without photovoltaic installations, ensuring diversity across gender, age, and education levels. The research received ethical approval from the Research Ethics Committee, Faculty of Philosophy, Jagiellonian University (approval no. 79_2024)

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    RODBUK Jagiellonian University in Kraków
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