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Alpha-Lipoic Acid Preserves Testicular Integrity Under 2.45 GHz Electromagnetic Radiation by Restoring Redox and Inflammatory Balance
No full textBackground/Objective: Electromagnetic radiation (EMR) from wireless technologies hasraised concerns about male reproductive health. We aimed to evaluate the protective roleof alpha-lipoic acid (ALA), a potent antioxidant, against testicular alterations induced by2.45 GHz EMR. Methods: Twenty-eight adult male rats were randomly divided into fourgroups: control, EMR, ALA, and ALA+EMR. Animals in the EMR and ALA+EMR groupswere exposed to EMR for 2 h/day for 1 month. Testicular tissues were examined histologically, stereologically, and immunohistochemically, while serum samples were analysedbiochemically. Results: EMR exposure caused marked structural damage, including disruption of seminiferous tubule architecture, increased collagen deposition, and expansion oftubular and interstitial volumes. These pathological changes were primarily prevented inthe ALA+EMR group. Immunohistochemical analyses revealed increased IL-6 and TNF-αexpression following EMR exposure, whereas ALA supplementation significantly reducedthese inflammatory markers and restored AR, ZO-1, and ZO-2 expression. Biochemically,EMR reduced antioxidant enzyme activities (SOD, GSH, GPx) and elevated MDA levels,indicating oxidative stress; these parameters were reversed by ALA treatment. Conclusions: Collectively, our findings demonstrate that 2.45 GHz EMR induces oxidative stress,inflammation, and testicular injury, while ALA provides significant protection. Theseresults highlight the therapeutic potential of ALA as a protective agent against EMR-relatedreproductive toxicity and infertility risk.</p
Mustafa Taceddin el-Musa'nın Sâidûnâ Ale't-Tehallusi Mine'ş-Şuarâ Adlı Kısa Hikâye Koleksiyonunda Anlatım Teknikleri
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Evde Sağlık Hizmeti Alan Yaşlı Bireylerde Malnütrisyonun Yaygınlığı, Risk Faktörleri ve Tedavi Yaklaşımları
No full textThe aim of this study was to evaluate the prevalence of malnutrition, associated risk factors, and treatmentapproaches in elderly individuals receiving home health care based on current evidence. As the method,PubMed, Scopus, and Web of Science databases were searched for articles published between 2015 and2025, including cross-sectional studies conducted in Iran, Sweden, the Netherlands, and Norway, as well asrecent studies from Türkiye. Findings showed that the prevalence of malnutrition among elderly home healthcare recipients ranged from 8% to 20%, while the risk of malnutrition was reported between 40% and 60%.Similar results were observed in studies from Türkiye, where advanced age, living alone, polypharmacy,chronic disease burden, and functional dependence were identified as major risk factors. The literature alsohighlights that the Mini Nutritional Assessment (MNA) and its short form (MNA-SF) are valid and reliablescreening tools with strong predictive value for frailty and mortality. In conclusion, malnutrition is acommon and critical health problem in older adults receiving home health care. Recommendations includeroutine nutritional screening during home visits, the use of oral nutritional supplements, providing enteral orparenteral nutrition when indicated, consultation with dietitians, strengthening nursing follow-up, andadopting a multidisciplinary care approach. Additionally, caregiver education and individualized nutritionalcare plans are suggested strategies to prevent malnutrition and improve the quality of life of elderlyindividuals in home health care settings. </p
Metal ion selectivity feature and synthesis of axially bis(3-(1,1-diphenylethoxy)propanoate) substitute silicon phthalocyanine
No full textIn this study, first 3-(1,1-diphenylethoxy) propionic acid was obtained from the reaction of 1,1-diphenylethanol and 3-chloropropionic acid. Bis(3-(1,1-diphenylethoxy) propanoate) silicon phthalocyanine was obtained from the reaction of 3-(1,1-diphenylethoxy) propionic acid with SiPcCl2. The newly prepared compounds were characterized by 1H NMR, FT-IR, mass spectrometry and UV-vis spectroscopy. The singlet oxygen quantum yield for silicon phthalocyanine, which has the potential to be a photosensitizer, was determined as 0.13 by chemical method. Finally, metal ion selectivity of bis(3-(1,1-diphenylethoxy) propanoate) silicon phthalocyanine was determined by UV absorption spectroscopy. A total of 11 metal ions (Mg2+, Mn2+, Na+, Ni2+, Zn2+, Fe3+, Ba2+, Cd2+, Cu2+, Co2+, and Ag+) were used for testing. Of these metal ions, only the Fe3+ ion was selectively determined