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Detection of secretory immunologlobulin A (aIgA) in human breast milk against Cronobacter sakazakii, Salmonella typhimurim, and AND Staphylococcus aureus.
No full textThis study aims to detect the presence and determine the amount of sIgA in fifteen fresh-then-stored human breast milk samples against Cronobacter sakazakii, Salmonella typhimurium, and Staphylococcus aureus. Moreover, this study aims to determine which between fresh and stored breast milk the better source of sIgA is, using titers as basis.
Enzyme-linked immunosorbent assay (ELISA) was used to detect the presence of sIgA against the bacteria. The amount, in titer, was determined using an established cutoff value.
Secretory IgA was detected against C. sakazakii, S. typhimurium, and S. aureus through ELISA. Mean titers of sIgA in fresh breast milk was higher than those in stored breast milk but a statistically significant difference was found only in those against S. typhimurium (t-test: p-value = 0.044). Comparison within the groups of fresh and stored breast milk through one-way ANOVA showed no significant differences.
Breast milk possesses a protective attribute against C. sakazakii, S. typhimurium, and S. aureus, as evidenced by the detection through ELISA, and this may serve as additional basis for recommendation of breast milk for infant consumption. SIgA amounts in the samples decreased after storage but a significant difference was found only in those against S. typhimurium. SIgA reaction to varying antigens was found to be consistent throughout all samples
BOSOM Calculator: A Breast Cancer Outcome - Survival Online Measurement Calculator using Data Mining and Predictive Modeling on SEER data
No full textIllnesses of high mortality rate such as breast cancer elicit questions related to
the patient’s time left to live. The common methods used to arrive at an estimate
include comparing the patient’s health condition to previous medical records and
treatments, referral to statistically-computed survival rates based from historical
records, or consulting another breast cancer expert.
The application of data mining on medical records to create predictive models
for cancer survivability has been proven to hold significant accuracy by numerous
scientific and applied researches throughout the years. Agrawal et al.’s “Lung
Cancer Outcome Calculator” provides a framework for developing a predicted
survival calculator for different cancers based on a patient’s health condition.
This research aims to develop the Breast Cancer Outcome - Survival Online
Measurement Calculator (BOSOM Calculator), an online application that takes a
patient’s clinical cancer data to give a predicted cancer survival based on a dataset
from the Surveillance, Epidemiology, and End Results Program (SEER)
Evaluation of three candidate DNA barcoding loci in Ficus (Moraceae) of the Philippines.
No full textDNA barcoding is a technique that produces a quick and reliable species–level identification between closely related and highly diverse species among all forms of life by making use of short DNA sequences from standardized genome sites. Ficus, as having diverse morphology and habit as well as economic, ecological, and pharmaceutical importance is a very good plant subject where DNA barcoding can be applied. In this study, where six indigenous Ficus species were used, the appropriateness of three candidate barcoding loci rbcL, trnH-psbA, and ITS to barcode Philippine endemic Ficus was assessed in terms of these criteria: universality, discriminatory power, and resolution of species. Results reveal that both trnH-psbA and ITS got 100% PCR success rate and 67% sequencing success score, whereas rbcL got 67% PCR success score but 100% sequencing success score. trnH-psbA performed best in terms of discriminatory power, having the highest variable informative site (71.37%), highest mean interspecific distance (0.483225 ± 0.198876). ITS ranked next to trnH-psbA since it was able to generate 100% resolution of species and comparable mean intraspecific distance score with trnH-psbA. rbcL failed to resolve any species correctly, thus it has 0% resolution of species. The proponents of this study recommended to increase sample size and to include species which are difficult to distinguish morphologically to test the discriminatory abilities of the loci
Philippine Society of Newborn Medicine's Neonatal - Perinatal Database and Query Builder
No full textMaternal and neonatal mortality and morbidity have been major concerns of the
health sector. This study proposes a framework composed of a patient registry
system that would store neonatal patients' medical records and provide maternal
and neonatal health statistics and a query builder that will allow researchers to
query in the database for research purposes which should be an effective and
intelligent tool to improve maternal and neonatal health care in the country
Pagsusuri sa sosyo-ekonomikong epekto ng large-scale mining sa bayan ng Sta. Cruz, Zambales.
No full textAng pagtaas ng antas ng pangangailangan para sa suplay ng non-renewable resources gaya na lamang ng mga metaliko at di-metalikong mineral ay siyang naghudyat sa pagpapalawig ng mga malalaking operasyon ng mga minahan upang matugunan ang pangangailangan sa nabanggit na likas yaman. Ang pag-usbong ng probinsiya ng Zambales bilang mining capital ng bansa, dahil na sa angkin nitong malaking bilang ng reserba ng chromite at nickel, na siya namang pangunahing ginagamit sa iba’t ibang pandaigdigang industriya, ang naghikayat sa mga kompanya ng pagmimina at dayuhang korporasyon na dito mamuhunan. Matatagpuan ang konsentrasyon ng mga Sa kabila ng patuloy na paglaki at paglago ng industriya ng pagmimina ayon sa gobyerno, taliwas naman ang naging epekto nito sa kabuhayan, empleyo, kalusugan at kapaligiran sa komunidad
PALSIPIKADONG KAUNLARAN: isang pag-aaral ukol sa mga isyu at asuntong kinakaharap ng Charoen Pokphand Food Philippines.
No full textAng pagdami ng mga multinasyunal na kumpanya ay isang malinaw na manipestasyon ng globalisasyon. Ang Pilipinas, bilang isang bansa na nasa ikatlong daigdig, ay isa sa mga paboritong lugar na paglagyan ng kapital ng mga naglalakihang multinasyunal na kumpanya dahil na rin sa mga pribilehiyong ibinibigay nito. Isa sa mga dayuhang namuhunan sa bansa ang Charoen Pokphand Foods Corporation (CP), isang kumpanyang nanggaling sa Thailand na kasalukuyang nangangasiwa sa iba't ibang kabuhayan sa buong mundo.
Kaugnay ng pagpasok ng nasabing kumpanya sa bansa ay nananawagan ang iba't ibang mga organisasyon na bawasan o hindi bigyan ng mga insentibo ang CP dahil nakokompromisa diumano nito ang lokal na agro-industriya. Sa pananaliksik na ito ay tinalakay ang mga isyung kinakaharap ng CP gayundin ang epekto nito sa lokal na mga namumuhunan. Inirerekomenda ng pag-aaral na ito na igiit ang pag-aalis ng mga insentiba sa mga dayuhang namumuhunan nang sa gayon ay hindi na maakit ang iba na dito mangapital – upang maiwasan ang pagkakaroon ng dayuhang monopolyo sa iba't ibang produkto sa Pilipinas
Occurrence of imposex and bioaccumulation of lead in the soft body tissues of Volema (Pugilina) cochlidium in Bacoor Bay, Cavite.
No full textThis study aimed to determine the correlation between the occurrence of imposex and the bioaccumulation of total lead in the hepatopancreas of Volema (Pugilina) cochlidium collected in Bacoor Bay, Cavite. The snail samples were dissected and the reproductive organs were examined for imposex identification while the hepatopancreas were used for heavy metal analysis of total lead concentration using atomic absorption spectrophotometry. Results showed that 50% of the females are imposex-affected and no reversal of sex ratio was observed. The bioaccumulation of total lead and the occurrence of imposex have an insignificant positive correlation based on the correlation analysis of the hepatopancreas’ total lead concentration (ppm) and the penis length (mm) of imposex-affected females. Due to this insignificant positive correlation, further studies should be conducted to confirm whether Relative Penis Length Index (RPLI) and Relative Penis Size Index (RPSI) values could be used as biomonitoring tools for total lead pollution in water bodies
Avicennia marina (Forssk.) Vierh. as phytoaccumulator of sediment heavy metals in the Las Piñas – Parañaque Critical Habitat and Ecotourism Area (Philippines).
No full textLas Piñas-Parañaque Critical Habitat and Ecotourism Area (LPPCHEA), being the last coastal frontier of Metro Manila, functions as a sink to a variety of pollutants including heavy metals. Its mangrove forest is known to accumulate heavy metals but such uptake is not conclusive of its capacity to alleviate environmental pollution. One of the methods used to verify such capacity of mangroves is to assess their Bioconcentration Factor (BCF) values which compare environmental and plant tissue concentrations of heavy metals. BCF values greater than one (>1) indicates efficiency of an organism to phytoaccumulate (Usman, 2013; EPA, 2007). Hence, in order to determine the phytoaccumulation efficiency of the mangrove forest in LPPCHEA, the research studied the BCF values of the dominant species, Avicennia marina, in the Long Island of LPPCHEA – one of the two islands in the area, and is situated in the middle of Manila Bay and Cavitex. Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP/OES) was used to detect and determine the Cr, Cu, and Pb concentrations of the ten composite samples of sediments, barks of stems, and pneumatophores in the area. It was found that Cu (37.41 ppm) had the highest concentration in the plant, followed by Pb (15.37 ppm) then Cr (4.94 ppm). However, taking into account the BCF values of the heavy metals, it was found that Pb (1.0913) was the highest phytoaccumulated heavy metal, followed by Cu (0.4403) then Cr (0.2806). The study suggests that A. marina is efficient in phytoaccumulating Pb in LPPCHEA. Furthermore, the root and bark tissues of the mangrove contribute equally to its phytoaccumulating capacity
Health risk assessment of indoor dust-associated heavy metals obtained from four Philippine public hospitals.
No full textHeavy metal concentrations in indoor dusts can have significant human health risks through inhalation, ingestion, and dermal absorption. The present study aims to assess the health risks of four heavy metal concentrations (Pb, Cd, Hg, and As) obtained in indoor dust from selected public hospitals in populous cities situated in Metro Manila and Batangas province. Non-carcinogenic risks were inferred by calculating the hazard quotients (HQ) and hazard indices (HI) of the heavy metals, while carcinogenic risks were stipulated by obtaining their cancer risk values. Results show that Ospital ng Maynila possessed 1.44 mgkg-1 Pb, 0.02 mgkg-1 Cd, 0.74 mgkg-1 Hg, and 2.00 mgkg-1 As; Philippine General Hospital indoor dust yielded 0.53 mgkg-1 Pb, 0.48 mgkg-1 Hg, and 1.80 mgkg-1 As; Laurel Memorial Hospital had 0.23 mgkg-1 Pb, 0.35 mgkg-1 Hg, and 2.50 mgkg-1 As; and Lipa City District Hospital-Granja generated 0.15 mgkg-1 Hg, and 1.50 mgkg-1 As. These concentrations all yielded HQ<1 and HI<1, indications of their insufficiency to induce significant non-carcinogenic health detriments. Analysis on the carcinogenic heavy metals, Cd and As, showed cancer values on the lower limit of the carcinogenicity threshold, 1×10-6 - 1×10-4 . This concludes that as of date, there is no immediate concern over the heavy metal concentrations in the sample sites. However, additional caution is advised for people who are susceptible for long-term exposure due to the observed high carcinogenic risk that comes with chronic heavy metal dosage
Iskwater sa sariling lupa: Isang pagtatasa sa implementasyon ng Indigenous Peoples Rights Act
No full textItinuturing na Perlas ng Silangan, ang Pilipinas ay nagtataglay ng masaganang mineral at likas na yaman. Sa ating kabundukan matatagpuan ang mga endemikong hayop at halaman; sa ating kapatagan at karagatan naman ay ang masaganang ani at iba’t ibang yamang-tubig. Ang mga ito ay patunay na ang Pilipinas ay isang paraiso. Sagana man tayo sa likas na yaman, isang malaking kabalintunaan na ang mga katutubong siyang naglinang sa ating mga likas na yaman ay pinapatay ng mga mapagbalatkayong polisiya. Kakambal ng mga katutubo ang lupa. Wari sila’y mga halamang mapipigtal ang buhay sa oras na alisin sa lupang tinubuan.
Sinisiyasat sa pag-aaral na ito ang Indigenous People’s Rights Act na itinuturing bilang isa sa mga pinakauna at pinakakomprehensibong batas sa buong mundo na nangangalaga at nagtataguyod ng karapatan at kapakanan ng mga katutubo. Sinisuguro ng batas na ito na iabante ang karapatan ng mga katutubo sa kanilang lupa at lupaing ninuno at sariling pagpapasya. Hihimayin sa pananaliksik na ito ang laman ng Batas IPRA at aaralin kung tumutugma sa kasalukuyang kalakaran ang mga layunin ng batas. Sa pamamagitan ng mga panayam at mga pag-aaral sa mga naunang pananaliksik, napatunayan na ginagamit ang IPRA bilang isang kasangkapan upang mapabilis ang proseso ng paggalugad sa mga lupaing ninuno at kalauna’y magreresulta sa pandarambong sa kalikasan at pangakamkam sa mga lupang ninuno