WPSphere Repository (William Paterson University)
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A play performed at the auditorium in Hunziker Hall at New Jersey State Teachers College at Paterson
No full textA play is performed at the auditorium in Hunziker Hall at New Jersey State Teachers College at Paterson. Photograph is undated. Date range is approximate
Dissecting the cis and trans elements that regulate adjacent-gene coregulation in Saccharomyces cerevisiae
Get PDFThe relative positions that genes occupy on their respective chromosomes can play a critical role in determining how they are regulated at the transcriptional level. For example, a significant fraction of the genes from a variety of coregulated gene sets, including the ribosomal protein (RP) and the rRNA and ribosome biogenesis (RRB) regulons, exist as immediate, adjacent gene pairs. These gene pairs occur in all possible divergent, tandem, and convergent orientations. Adjacent-gene pairing in these regulons is associated with a tighter transcriptional coregulation than is observed for nonpaired genes of the same regulons. In order to define the cis and trans factors that regulate adjacent-gene coregulation (AGC), we conducted a mutational analysis of the convergently oriented RRB gene pair MPP10-YJR003C. We observed that coupled corepression of the gene pair under heat shock was abrogated when the two genes were separated by an actively expressed RNA polymerase (Pol) II transcription unit (the LEU2 gene) but not when the inserted LEU2 gene was repressed. In contrast, the insertion of an RNA Pol III-transcribed tRNA (Thr) gene did not disrupt the coregulated repression of MPP10 and YJR003C. A targeted screen of mutants defective in regulating chromosome architecture revealed that the Spt20, Snf2, and Chd1 proteins were required for coupling the repression of YJR003C to that of MPP10. Nucleosome occupancy assays performed across the MPP10 and YJR003C promoter regions revealed that the mechanism of corepression of the gene pair was not related to the repositioning of nucleosomes across the respective gene promoters.Version of Record (VoR
Students on the roadway between Hunziker Hall and the Student Union building at Paterson State College in the mid 1960s
No full textStudents walk on the roadway between Hunziker Hall and the Student Union building at Paterson State College in the mid 1960s. Photograph is undated. Date range is approximate
Prof. David Haxton teaching computer animation at William Paterson University
No full textProf. David Haxton helps students develop their technical skills in computer animation at William Paterson University. Undated. Date range is approximate
The groundbreaking ceremony for construction of the Student Center at William Paterson College
No full textThe groundbreaking ceremony for construction of the Student Center at William Paterson College. With acting president Frank Zanfino at right
Rufus Reid of William Paterson College adresses an audience at Willowbrook Mall in Wayne, NJ
No full textBassist Rufus Reid, former Director of Jazz Studies at William Paterson College, adresses an audience at Willowbrook Mall in Wayne, NJ before a performance of the WPC student jazz ensembe. Undated. Date range is approximate
Students study at the Multimedia Language Center at William Paterson University
No full textStudents study at the Multimedia Language Center at William Paterson University. Undated. Date range is approximate
The side entrance of the Atrium at William Paterson University
No full textThe side entrance of the Atrium at William Paterson University. Photograph is undated