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Investigation of Mental Fatigue in Individuals With Tinnitus
No full textObjective: Mental fatigue is a common but understudied symptom in individuals with tinnitus. This study aimed to examine the relationship between tinnitus-related distress, anxiety symptoms, and mental fatigue. Methods: A total of 119 participants (52 with tinnitus, 67 healthy controls) were included. All participants completed the Mental Fatigue Scale (MFS) and Generalized Anxiety Disorder-7 (GAD-7). The tinnitus group also completed the Tinnitus Handicap Inventory (THI), Visual Analog Scales (VAS), and psychoacoustic assessments (pitch matching, loudness level, minimum masking level). Group comparisons and correlation analyses were conducted. Results: MFS scores were significantly higher in the tinnitus group than in controls (11.74 +/- 5.51 vs. 8.13 +/- 4.34, p = 0.015, d = 0.45). A moderate positive correlation was found between mental fatigue and anxiety symptoms (r = 0.44, p = 0.001). Within the tinnitus group, mental fatigue was weakly associated with THI and VAS attention deficit scores (r = 0.31, p = 0.022 and r = 0.30, p = 0.033, respectively), though these did not survive correction for multiple comparisons, nor with tinnitus loudness, masking levels, sleep disturbance, or hearing loss. Conclusion: Mental fatigue in tinnitus appears more closely related to psychological and attentional factors than to auditory variables. Routine screening for fatigue and cognitive complaints may support more comprehensive tinnitus management and improve patient outcomes
Üniversite-Sanayi İş Birliğinde Kariyer Planlamasına Yönelik Bir İyi Uygulama Örneği: Hacettepe Üniversitesi Kariyer Merkezi
No full textBu makalede, dijital dönüşüm ve teknolojik gelişmelerin şekillendirdiği günümüz işgücü piyasasında üniversitelerin kariyer planlamasındaki rolü ve üniversite-sanayi iş birliğinin bu süreçteki önemi Hacettepe Üniversitesi Kariyer Merkezi (KARMER) örneği üzerinden incelenmektedir. Üniversite-sanayi iş birliğini merkeze alan KARMER; kariyer danışmanlığı, müfredat entegrasyonu, mikro yeterlilik programları, dijital platformlar ve kariyer fuarları gibi çeşitli bileşenleri kapsayan bir model sunmaktadır. Modelin başarısındastratejik yönetişim, paydaş katılımı, dijitalleşme ve sürdürülebilirlik belirleyici faktörler olarak öne çıkmaktadır. Bu iyi uygulamaörneği, diğer üniversiteler için ölçeklenebilir ve uyarlanabilir bir kariyer planlaması çerçevesi sunmaktadır. Kariyer Fuarı’25 verileriışığında işverenlerin mezunlardan beklentilerinin de değerlendirildiği çalışmada, üniversitelerin öğrencilerini değişen iş dünyasınahazırlamada atabileceği stratejik adımlara dair yol gösterici öneriler sunulmaktadır.In this article, the role of universities in career planning in the current labour market, shaped by digital transformation and technological developments, and the importance of university-industry cooperation in this process are examined through the exampleof Hacettepe University Career Center (KARMER). KARMER, which focuses on university-industry cooperation, offers a model thatincludes various components such as career counselling, curriculum integration, micro-qualification programmes, digital platforms,and career fairs. Strategic governance, stakeholder participation, digitalisation, and sustainability stand out as determining factorsin the success of the model. This best practice example provides a scalable and adaptable career planning framework for other universities. The study, which also analyses the expectations of employers from graduates in the light of Career Fair’25 data, providesguiding recommendations on the strategic steps universities can take to prepare their students for the changing business world.</div
İlkokul 4. Sınıf Fen Bilimleri Ders Kitabındaki Modsal Betimlemelerin Analizi
No full textBu çalışmada ilkokul 4. sınıf fen bilimleri ders kitabında yer alan modsal betimlemelerin belirlenmesi ve çeşitli ölçütler açısından incelenmesi amaçlanmıştır. Doküman incelemesinin kullanıldığı bu araştırmada verilere ulaşmak için 4. sınıf fen bilimleri ders kitabından yararlanılmıştır. Fen bilimleri ders kitabındaki modsal betimlemelerin içerik analizi sonucunda mod türleri içerisinde en fazla fotoğrafın yer aldığı, kullanılan modların çoğunlukla açık bir şekilde ifade edildiği, mod ve metin arasındaki ilişkinin yeterli düzeyde olduğu ancak öğrenciyi moda yönlendirecek bağlantılara yeterince yer verilmediği, modların başlık özelliklerinin çoğunlukla uygun olduğu tespit edilmiştir. Kitapta öğrencilerin yanlış öğrenmelerine sebep olabilecek hatalı, eksik ve belirsiz modlar da yer almaktadır. Bu sonuçlara yönelik olarak fen bilimleri ders kitaplarındaki tüm ünitelerin içerikleri doğrultusunda farklı türlerde modların kullanımına yer verilmesi önerilmektedir. Fen bilimleri ders kitaplarında var olan modların niteliğinin artırılması da araştırmanın önerileri arasında yer almaktadır.In this study, it was aimed to determine the modes of representation in a 4th grade primary school science textbook and to analyze them in terms of various criteria. In this study, in which document analysis was used, the 4th grade science textbook was used as source of data. As a result of the content analysis of the modes of representation in the science textbook, it was determined that there were mostly photographs among the mode types, the modes used were mostly clearly expressed, the relationship between the mode and the text was sufficient, but the links that lead students to the mode were weak, and the caption features of the modes were mostly appropriate. The book also contained inaccurate, incomplete and ambiguous modes that may cause students to mislearn the content. In line with these results, it is suggested that different types of modes should be used in science textbooks in line with the content of all units. Improving the quality of existing modes in science textbooks is also among the recommendations of the stud
Development of molnupiravir and peramivir loaded liposome formulations for combined antiviral therapy
No full textThe pandemic caused by the SARS-CoV-2 virus has led scientists to intensify research on antiviral drugs and vaccines. As a result of these studies, it was observed that molnupiravir (MLP) and peramivir (PRV) could be used against pandemic. MLP affects SARS-CoV-2 replication, but it necessitates high doses, which can cause adverse effects in patients. PRV is a neuraminidase inhibitor, but the bioavailability of the drug after oral administration is very low. In this study, MLP-, PRV-loaded and combined liposome (COMB-Lipo) formulations were prepared via the thin film hydration method. Phospholipon 90 G-based formulations exhibited the most favorable characteristics, with a particle size of 111-145 nm, a polydispersity index (PDI) of less than 0.4, and a zeta potential (ZP) of 6-12 mV). Cell culture studies demonstrated that developed stable formulations are nontoxic to L929 and Vero E6 cells. Antiviral activity assessments against SARS-CoV-2 suggested the effectiveness of liposomes in inhibiting viral activity. These findings demonstrate that a possible synergistic effect of the newly developed sustained-release COMB-Lipo formulation is suggested with the complementary antiviral mechanisms of the combined agents. As a result, the therapeutic potential of co-delivery of anti-SARS-CoV-2 drugs for pulmonary application is considered a promising approach for long-acting treatment of COVID-19
Local Authority Experiences in Disaster Response: A Case Study of Mukhtars in Hatay, Türkiye after the February 6, 2023 Earthquakes
No full textThis study examines the experiences of mukhtars in Hatay, T & uuml;rkiye, following the February 6 earthquakes. Framed by the "institutional voids" concept, this qualitative study finds that mukhtars became critical first responders but were systemically overburdened by the collapse of formal governance. Validated through analytical triangulation, the findings detail severe challenges in communication, resource management, and damage assessments. The study concludes that enhancing community resilience requires moving beyond theoretical recognition to the formal integration of hyper-local actors, such as mukhtars, into centralized disaster governance, supported by clear legal and institutional frameworks
MASLD Tanılı Hastalarda Kombine Egzersiz Programının Yaşam Kalitesi Üzerine Etkisi: Erken Sonuçlar
No full textResimli Çocuk Kitaplarında Çocuk Haklarının İncelenmesi
No full textErken yaşlarda hak kavramının kazandırılması önemli görülmekle birlikte bu dönem için soyut bir kavramdır. Soyut kavramların çocuklara kazandırılmasında etkili araçlardan biri resimli çocuk kitaplarıdır. Alanyazında Türkiye’de resimli çocuk kitaplarında çocuk haklarını inceleyen sınırlı çalışmaya rastlanmış ve bu çalışmaların geçmiş yıllara ait olduğu belirlenmiştir. Bu bağlamda değişen şartlar ve güncel kitaplarda çocuk haklarına nasıl yer verildiğinin araştırılması güncel bilgi ve içerikleri sunması açısından önemli görülmektedir. Araştırma nitel yöntemle tasarlanmıştır. Kitaplar, ölçüt örnekleme yöntemiyle belirlenmiş 100 resimli çocuk kitabıdır. Veriler doküman inceleme yöntemiyle toplanmış ve içerik analiziyle çözümlenmiştir. Sonuç olarak; çocuğun gelişimsel haklarına yer verilirken bu hakların nasıl desteklenmesi gerektiğine yönelik sınırlı içerik olduğu görülmüştür. Yaşamsal haklar bağlamında eşitlik, barış içinde aileyle yaşamaya yapılan vurgunun çocuğun gelişimiyle paralel olduğu söylenebilir. Ayrıca resimli çocuk kitaplarında en az korunma hakkına yönelik içerik sunulmuştur.Although it is considered important to teach the concept of rights at an early age, it is difficult to comprehend abstract concepts during this period. One of the effective tools for teaching abstract concepts to children is illustrated children's books. The existing literature in Turkey was found to include a limited number of studies examining children's rights in illustrated children's books and it was determined that these studies dated from previous years. In this context, it is considered important to investigate how children's rights are included in changing conditions and current books in terms of providing up-to-date information and content. The research was designed using qualitative method. The books consist of 100 illustrated children's books selected through the criterion sampling method. The data were collected through document analysis and analysed using content analysis. As a result, while children's developmental rights are included, there is limited content on how these rights should be supported. In the context of vital rights, it can be said that the emphasis on equality and living with the family in peace is parallel to the child's development. In addition, content on the right to protection was presented the least in the illustrated children's books
Unveiling Factors and Strategies to Alleviate Anxiety Among EFL Student Teachers in Online and In-Person Practicums
No full textOptimal Detection for a Prospect Theoretic Variant of the Neyman-Pearson Problem
No full textA prospect theoretic variant of the Neyman-Pearson (NP) detection problem is proposed for a behavioral (human) decision maker, who perceives distorted versions of the detection and false alarm probabilities. The perceived probabilities are obtained as strictly monotonic transformations of the true probabilities via a probability weighting function employed in prospect theory. It is assumed that the the decision maker can employ time-sharing among a number of detectors in order to maximize the average perceived detection probability subject to a constraint on the average perceived false alarm probability. It is shown that time-sharing between at most two distinct NP decision rules is optimal. A sufficient condition for improvability of the detection performance via time-sharing is presented based on the convexity properties of the transformed version of the receiver operating characteristic curve corresponding to the likelihood ratio detector. Numerical examples are provided to corroborate the theoretical results
Effects of Turkish fathers' gender role attitudes, marital adjustment, and maternal attachment on prenatal paternal attachment in third trimester
No full textThe paternal attachment that fathers establish with their infants during pregnancy forms the basis of postnatal relationships and strongly affects the dynamics within the family. The present study was conducted to determine the effects of fathers' gender role attitudes, marital adjustment, and maternal attachment on prenatal paternal attachment in the third trimester in Turkiye. This descriptive cross-sectional study was conducted between January and November 2023 and included 255 fathers whose partner was between 28 and 40 weeks old and who had a healthy pregnancy and their partners in the obstetric outpatient clinic of one of the most advanced university hospitals. The relevant data for the study were collected via the "Descriptive Characteristics Form," "Gender Role Attitudes Scale," "Marital Adjustment Scale," "Prenatal Attachment Inventory," and "Paternal Antenatal Attachment Scale." The descriptive characteristics data form was completed by the fathers, the gender role attitudes scale, the marital adjustment scale, and the prenatal attachment scale were completed by the fathers, and the prenatal attachment inventory was completed by their partners. Descriptive statistics, independent t-tests, one-way ANOVA, the Bonferroni correction, post hoc tests, and multiple linear regression were used to analyze the data. Among the descriptive characteristics evaluated, paternal age (p = .075) and perceived economic status (p = .216) were not revealed to have any effect on prenatal paternal attachment. Gender role attitudes (p = .238) and maternal attachment (p = .178) also had no effect on paternal attachment. Marital adjustment affected prenatal paternal attachment (p = .000). Since marital adjustment was found to be effective on paternal attachment in this study, it is recommended that this variable be integrated into prenatal care practices