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Adaptation and Validation of Short Form of the Foreign Language Enjoyment Scale (S-FLES) into Turkish
No full textWith the increasing interest in Positive Psychology within the realm of L2 learning, the role of positive emotions, particularly Foreign Language Enjoyment (FLE) has garnered attention in Second Language Acquisition research (Dewaele & MacIntyre, 2014). Despite the growing interest in FLE in Turkey, the widely used Foreign Language Enjoyment Scale (FLES) has been employed without thoroughly validating its psychometric properties in the Turkish context. This study addresses this gap by psychometrically validating and adapting the Turkish version of the Short Form of the Foreign Language Enjoyment Scale (S-FLES) developed by Botes et al. (2021). The translated version was administered to 390 university-level Turkish EFL (English as a Foreign Language) students in Turkey. Results from Confirmatory Factor Analysis indicated acceptable levels of goodness of fit for the 3-factor and 9-item model, confirming the structural validity of the Turkish S-FLES. The results also demonstrated that the scale has discriminant validity and high internal consistency. With its robust psychometric properties, the validated S-FLES in Turkish can be a valuable resource for educational researchers, offering a standardized scale for investigating the factors influencing FLE in the Turkish context.</jats:p
Investigating the effect of coating and synthesis parameters on La<sub>1-x</sub>Sr<sub>x</sub>MnO<sub>3</sub> based core-shell magnetic nanoparticles
No full textMagnetic nanoparticles are an important class of functional materials that have unique magnetic properties due to their reduced size (<100 nm) and have the potential for use in many fields. In the preparation of magnetic nanoparticles, factors such as intrinsic magnetic properties, surface coating, size and shape of the particles, surface charge and stability are very important. In this regard, carefully determining the synthesis parameters of magnetic nanoparticles and particle coating materials is of critical importance in the application area chosen for the material. In this study, La1-xSrxMnO3 (x = 0.27, 0.30, 0.33) magnetic nanoparticles (MNPs), carbon-coated magnetic nanoparticles in core-shell structure (C@MNP) and their derivatives integrated into graphene oxide (GO-C@MNP) were synthesized and their properties were investigated in detail for their use in possible future application studies. The crystal structure of perovskite compounds with Pbnm symmetry remains unchanged after carbon coating but shrinks in volume due to its amorphous structure. The magnetic behavior of the uncoated and coated materials is almost identical, but the Curie temperature of the compounds shifts to a higher temperature. In the specific absorption ratio (SAR) measurements performed, it was found that the best SAR value for carbon-coated MNPs was 12.9 W/g at x = 0.27. By integrating the MNPs into graphene oxide, heat is easily distributed regionally, and this shows that the structures can be ideal candidates for applications such as hyperthermia, drug carriers, tissue repair, and cellular therapy including cell labeling and targeting. Perovskite-structured manganite materials were selected for their suitability in controlled production, where the Curie temperature can be tuned near the therapeutic temperature by adjusting the doping levels, making them ideal for magnetic hyperthermia applications. In this study, for the first time, the nanoparticle surfaces were coated with carbon, which was chosen not only due to carbon's non-magnetic nature but also because it provides an ideal platform for future combined biomedical applications such as drug delivery systems
Unsiloed agroforestry research and policy: Livelihood and multifunction as chestnut<i> (Castanea</i><i> sativa)</i> management priorities for Türkiye
No full textIn this study, we investigate variation in the priorities for the chestnut tree held by stakeholders across T & uuml;rkiye in order to highlight the importance of unsiloed research and policy in the study area and beyond. We designed our study to evaluate the operating hypothesis of state agencies who manage the tree in sharp regional contrast, with the western provinces managed overwhelmingly for horticulture, and the northern provinces for silviculture. We utilized ethnobiological methodologies of plant trait preference cataloguing and freelisting to engage and analyze the priorities for chestnut trees for 96 stakeholder households across T & uuml;rkiye 's chestnut suitable territory. We found that no household utilized the tree for one purpose only, that every household used the tree for both its fruits and its timber, and that the vast majority utilized the tree for nuts, timber and one other category of use. We explored the resulting data using saliency analysis, multiple correspondence analysis and geospatial visualization through inverse distance weighting. We found no significant effect of western or northern location on priorities. Our findings substantiate conservation and livelihood development theories which advocate for unsiloed, interdisciplinary research informed by stakeholders, and also showcase an application of agroforestry as a framework for directly amplifying the priorities of livelihood practitioners in the formulation of land use policy. Insights generated by this study support recommendations for T & uuml;rkiye and beyond, including more thoroughly interdisciplinary research to perpetuate multifunctional use of trees as well as more regional and unified governmental strategies for conservation and rural livelihood viability
A Novel Porous Coating Method of Commercially Pure Titanium Using Silk Fibroin and UV Light for Biomedical Implant Applications
No full textSurface coatings for titanium implants have been actively investigated using numerous materials to improve biocompatibility and osteointegration. This study developed a novel porous coating method for titanium implants; we coated commercially pure titanium (Cp-Ti) using the photocurable properties of methacrylated silk fibroin (SilMA). Surface morphologies and alloying chemistry after coating were investigated by scanning electron microscopy (SEM) and EDS, while the biocompatibility of the SilMA-coated Cp-Ti was evaluated by the CCK-8 and live/dead assays. With various SilMA concentrations, uniform and strong SilMA coatings were obtained by UV light for both thin and thick coating methods. A universal mechanical testing machine evaluated the mechanical properties of SilMA coating. The interface adhesive strength of the coating taken by advanced centrifugal measurement was enhanced as the SilMA concentration increased. Cell cytotoxicity test results for 1, 3, 5, and 7 days revealed no toxic behavior in human dermal fibroblast cells. Cells on the SilMA-coated Cp-Ti revealed a higher proliferation and survival rate than those on the titanium without coating. These results show that this versatile coating method offers a tightly adhered bioactive coating of silk fibroin on titanium implants, demonstrating the potential for a universal coating method for use in a wide range of biomedical applications
Effect of Different Types of Concha Bullosa on Olfactory Function
No full textObjective: This study aimed to compare the effects of different types of concha bullosa (CB) on olfactory function using paranasal computed tomography (CT) findings and the Sniffin' Sticks test. Methods: A total of 107 patients (69 women and 38 men) were evaluated. The study group included 79 patients with CB, while the control group comprised 28 patients without CB. CB cases were classified into three subtypes according to the Bolger classification: lamellar (n=28), bulbous (n=25), and extensive (n=26). Paranasal CT scans were assessed by a radiologist to measure the olfactory cleft width, the distance between the turbinate and septum, and the volume of the turbinate bullosa. All participants completed the SNOT-22 and NOSE questionnaires. Olfactory function was evaluated using the Sniffin' Sticks test, and examinations were conducted by an otolaryngology specialist. Results: There were no significant differences between the groups in terms of age and gender (P > 0.05). The Sniffin' Sticks test score was significantly higher in the control group than in the CB group (p < 0.001). The control group had significantly higher odor scores than the lamellar and extensive groups (p = 0.002 and p = 0.042, respectively), but not the bulbous group (p=0.133). The volume of the concha bullosa (VCB and HCB) was significantly greater in the extensive CB group than in the lamellar and bulbous groups (both p < 0.001). No significant differences were observed in the right, left, or total olfactory cleft widths among the four groups (P > 0.05). Conclusions: Olfactory function, as measured by the Sniffin' Sticks test, was significantly better in the control group compared to the CB group. However, there were no significant differences in olfactory performance among the different CB subtypes. Additionally, olfactory cleft width did not differ significantly between groups. These findings suggest that while the presence of CB may be associated with reduced olfactory function, the subtype of CB and cleft width may not play a major role. Moreover, the reduction of olfactory function due to CB was minimal and not clinically meaningful.</p
A Low-Complication Valve-Sparing Aortic Root Surgery Technique: Our Experience with the Florida Sleeve
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Enjekte Edilebilir Hücre Taşıyıcısı Olarak PBAT Mikrotaşıyıcıların Geliştirilmesi ve Hücresel Etkileşimlerinin İncelenmesi
No full textTürkiye’de Yaratıcı Ayrıntılı Altyazı Çevirisi Üzerine Bir Alımlama Çalışması
No full textÇeviribilim araştırmaları arasında son dönemde yer edinmeye başlayan yaratıcı ayrıntılı altyazı çevirisi; sağır ve işitme engelli alıcıların ihtiyaçlarına daha yenilikçi bir bakış açısıyla yaklaşan ve yaratıcılık olgusu üzerinden, görsel-işitsel ürünlerin alımlama düzeylerini arttırmayı amaçlayan bir türdür. Yaratıcı ayrıntılı altyazı özellikle son yıllarda, sağır ve işitme engelli alıcı kitlenin medya içeriklerini daha derin ve bütünsel bir şekilde deneyimleyebilmesi için önemli bir adım olarak öne çıkmaktadır. Özünde altyazı çevirisinden hareketle ortaya çıkan ve yaşanan uluslararası ve ulusal gelişmeler neticesinde bugün dünyada ve ülkemizde yaygın bir şekilde kullanılmakta olan ayrıntılı altyazı çevirisini bir adım öteye taşımayı amaçlayan yaratıcı ayrıntılı altyazı çevirisi, alıcı kitleye daha zengin ve etkileşimli bir deneyim sunmayı hedeflerken aynı zamanda sağır ve işitme engelli alıcı kitlenin görsel-işitsel ürünleri alımlama düzeyleri üzerinde bir farklılık oluşturmayı amaçlar. Türkiye’de doktora düzeyinde yaratıcı ayrıntılı altyazı çevirisi üzerine devam etmekte olan bir araştırmadan yola çıkarak hazırlanan bu çalışma, bu yeni açılımın sağır ve işitme engelli alıcıların görsel-işitsel ürünlere erişimi üzerinde sağlayabileceği katkıları ve araştırma katılımcılarının geribildirimleri çerçevesinde edinilen nitel ve nicel veriler üzerinden yaratıcılık açılımının sınırlarını belirleyebilmeyi amaçlamaktadır.Creative subtitling for deaf and hard-of-hearing, which has recently gained prominence in translation studies, represents an innovative approach to enhance the reception of audiovisual products by Deaf and Hard-of-Hearing audiences through the lens of creativity. In recent years, creative subtitling for deaf and hard-of-hearing has emerged as a significant step toward enabling DHH audiences to experience media content more deeply and constituted. Built on the foundation of subtitling practices, this approach seeks to advance the scope of subtitling for deaf and hard-of hearing—widely utilized both globally and domestically due to international and national developments—by offering viewers a richer and more interactive experience. This research also aims to improve audiovisual products' reception and engagement levels for DHH audiences. This study, based on ongoing doctoral research in Turkey on creative subtitling for deaf and hard-of-hearing, investigates the potential contributions of this novel approach to enhancing accessibility for DHH audiences. Furthermore, it explores the boundaries of creative innovation in subtitling by examining the qualitative and quantitative research outcomes collected from participant feedback to assess the impact of creative subtitling on the accessibility and reception of audiovisual materials
Therapeutic drug monitoring in patients treated with vancomycin: a single center, prospective, observational, real-world study
No full textPurposeTherapeutic drug monitoring of vancomycin targeting an AUC/MIC ratio of 400-650 mg*h/L is required to ensure optimal therapeutic efficacy and safety in patients treated with vancomycin. The objectives of this study were to monitor vancomycin plasma peak and trough concentrations to calculate the area under the curve (AUC) to assess target achievement in real-world settings and to evaluate the relationship between AUC and acute kidney injury (AKI).MethodsIn this single-center cohort study, prospectively calculated vancomycin AUC and trough concentrations were extracted from the database and evaluated for achievement of therapeutic ranges for AUC and trough concentrations at a university hospital. Patients were evaluated for the development of AKI according to KDIGO guidelines.ResultsA total of 114 patients were included in the study. Vancomycin loading doses were initiated in 83.3% of patients, and 82.1% of patients received the appropriate weight-based dose. 79.8% of maintenance doses were appropriate. The median (min-max) values for peak, trough, and AUC were 23.25 (3.3-131.8) mg/L, 10.35 (0.6-56.4) mg/L, and 403(49-1786) mg/L*hour, respectively. The majority of values were outside the therapeutic target for both trough (65.3%) and AUC (63.7%). AKI was observed in 15.8% of patients. In patients without AKI, the median (min-max) trough concentration was 9.65 (0.60-45.30) mg/L and the AUC was 370 (49-1390) mg/L*hour.ConclusionsIn this study, only one-third of baseline concentrations were in the therapeutic range and were increased by up to two-thirds with dose adjustments. Therapeutic drug monitoring to achieve target concentrations is critical in patients treated with vancomycin