IRIS Università degli Studi dell'Aquila
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Per una teoria freudiana della letteratura, nuova edizione ampliata, con un saggio introduttivo di G. Mazzoni
“Francesco Orlando è uno dei pochi che nel corso del Novecento abbiano risposto alla domanda “che cos’è la letteratura” dicendo cose nuove e radicali” (Guido Mazzoni)
La letteratura preferisce sempre contenuti proibiti? C’è forse una parentela tra il linguaggio della letteratura e quello dell’inconscio? Se sì, quante e quali forme questa preferenza e questa parentela possono assumere? La risposta si trova in apertura del volume, in un saggio più volte ristampato in mezzo secolo, e che dà il titolo all’intero libro. Negli scritti successivi l’autore prosegue il discorso di un’applicazione logica e formale della psicanalisi agli studi letterari. Ci fa poi entrare nel laboratorio del suo personale e trentennale metodo critico. Altri due testi arricchiscono oggi la ristampa di questo classico della teoria: un’intervista sulla crisi dell’interpretazione dei testi dopo la svolta da lui definita “irrazionalista” di metà anni Settanta, e un saggio di autoanalisi letteraria che, pubblicato poco prima della morte, contiene nuovi spunti su come si crea il senso di un testo.
Questa nuova edizione apre quella di tutto il “ciclo freudiano” presso Quodlibet: a seguire, saranno disponibili sia Due lettere freudiane: Fedra e il Misantropo, che Illuminismo, barocco e retorica freudiana, i due libri che illustrano nella prassi la teoria e coi quali Per una teoria freudiana della letteratura compone quel ciclo unitario
Mapping European Educational Research: Insights from topic modelling of ECER abstracts
European educational research is heterogeneous. It contains diverse areas of inquiry, types of disciplinary knowledge, methodological approaches, and philosophical foundations. This raises questions about what European educational research is about and where its boundaries lie. On the occasion of the European Educational Research Association's 30th anniversary, and by use of the data mining technique topic modelling, this paper presents the results of an analysis of the abstracts database of the European Conferences on Educational Research (ECER; 1998-2024). In doing this, this paper uses the ECER abstracts database as a window to reflect upon and discuss the state and futures of the European educational research field. This study identifies 100 distinct topics in European educational research, defined as clusters of words that tend to be used together within the ECER abstracts. In addition to this, the study analyses the trajectory of these topics' prevalence over time. Based on these findings, we highlight four central thematical evolutions in order to instigate a debate about the scope, focus and future of the field. In a response to these four clusters, we identify three key issues for the research field: the effects of policy and funding programmes, the ongoing diversification, and the question of the centrality of education
Neoadjuvant Hedgehog Inhibitors for Locally Advanced Basal Cell Carcinoma: Insights from Two Real-world Cases
La ‘costanza’ e l’educazione di Alessandro. Su alcune occorrenze di mat. stæte e derivati nella letteratura tedesca medievale
Un altro modo di progettare. Hilda Selem, Vittoria Calzolari e altre storie dal programma Fulbright
Hadron colliders signatures of lepton number violation in the type II seesaw model
We examine the prospect of observing genuine lepton-number-violating (LNV) signals at hadron colliders in the context of the type II seesaw mechanism. The model features smoking gun signals involving same-sign di-leptons and jets that may be the primary observable channel in certain regions of the parameter space. The flavor composition of final-state charged leptons is related to the origin of neutrino masses and is correlated with other rare processes, such as neutrinoless double-beta decay. We review existing collider limits and provide sensitivity estimates from LNV signals at upcoming Large Hadron Collider runs, including nonzero mass splittings between triplet components
Towards a Database of Structural Typologies and Construction Systems in Steel for the Components Reuse/Repurpose
Steel has always expressed great potentiality for circular economy due to the high durability, remarkable flexibility and excellent recyclability, which allow the total reintegration into the production cycle. Steel structures at the end-of-life therefore represent a significant source of raw material for new buildings, reusing/repurposing the steel components and exploiting the embodied energy incorporated in them during the transformation and construction processes. In
the construction sector, the first application of circular strategies primarily concerned the materials recycle in the phase of building decommissioning through the management of controlled demolitions and the next reuse in production cycles. For reuse/repurpose, however, it is necessary to define new methods and tools coherent with the Italian laws. A useful preamble to start writing new systems of rules is understanding how much and what has been built of steel, creating a database of the most diffused structural typologies and construction systems in Italy since 1950. The paper describes the methodology of the cataloguing activity and its operational tools, validated on the collected cases, implemented with the aim of characterizing the steel components, potentially reusable according to predefined parameters. The work is part of the Project of Relevant National Interest (PRIN) “Buildings and Circular Economy. Steel from production to post-production. Law and responsibility issues”, conceived with the goal of expanding circular economy strategies in the construction sector through the development of practices/processes useful for supporting the design and management of possible post-production scenarios of structural systems and steel components
First-year treatment response predicts the following 5-year disease course in patients with relapsing-remitting multiple sclerosis
Predicting long-term prognosis and choosing the appropriate therapeutic approach in patients with Multiple Sclerosis (MS) at the time of diagnosis is crucial in view of a personalized medicine. We investigated the impact of early therapeutic response on the 5-year prognosis of patients with relapsing-remitting MS (RRMS). We recruited patients from MSBase Registry covering the period between 1996 and 2022. All patients were diagnosed with RRMS and actively followed-up for at least 5 years to explore the following outcomes: clinical relapses, confirmed disability worsening (CDW) and improvement (CDI), EDSS 3.0, EDSS 6.0, conversion to secondary progressive MS (SPMS), new MRI lesions, Progression Independent of Relapse Activity (PIRA). Predictors included demographic, clinical and radiological data, and sub-optimal response (SR) within the first year of treatment. Female sex (HR 1.27; 95 % CI 1.16–1.40) and EDSS at baseline (HR 1.19; 95 % CI 1.15–1.24) were independent risk factors for the occurrence of relapses during the first 5 years after diagnosis, while high-efficacy treatment (HR 0.78; 95 % CI 0.67–0.91) and age at diagnosis (HR 0.83; 95 % CI 0.79–0.86) significantly reduced the risk. SR predicted clinical relapses (HR = 3.84; 95 % CI 3.51–4.19), CDW (HR = 1.74; 95 % CI 1.56–1.93), EDSS 3.0 (HR = 3.01; 95 % CI 2.58–3.51), EDSS 6.0 (HR = 1.77; 95 % CI 1.43–2.20) and new brain (HR = 2.33; 95 % CI 2.04–2.66) and spinal (HR 1.65; 95 % CI 1.29–2.09) MRI lesions. This study highlights the importance of selecting the appropriate DMT for each patient soon after MS diagnosis, also providing clinicians with a practical tool able to calculate personalized risk estimates for different outcomes