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中生代初頭における異なる気候区での古風化変動史の比較
No full text研究種目：基盤研究(C)研究期間：2014～2016課題番号：26400485研究代表者：吉田 孝紀研究者番号：00303446Other2014～2016年度科学研究費助成事業（基盤研究(C)）研究成果報告書 課題番号：26400485 研究代表者：吉田 孝紀research repor
ホスホニウムベタインを用いたデザイン型マルチ機能触媒の設計開発
No full text研究種目：研究活動スタート支援研究期間：2015～2016課題番号：15H06242研究代表者：戸田 泰徳研究者番号：60758978Other2015～2016年度科学研究費助成事業（研究活動スタート支援）研究成果報告書 課題番号：15H06242 研究代表者：戸田 泰徳research repor
石灰岩層を使ったCO2急速削減のためのフラクタル石灰岩モデルによる溶解速度予測式
No full text研究種目：挑戦的萌芽研究研究期間：2015～2016課題番号：15K14039研究代表者：中屋 眞司研究者番号：70313830Other2015～2016年度科学研究費助成事業（挑戦的萌芽研究）研究成果報告書 課題番号：15K14039 研究代表者：中屋 眞司research repor
セルロース高次階層構造に対するセルロース膨潤タンパク質の作用
No full text研究種目：挑戦的萌芽研究研究期間：2015～2016課題番号：15K14769研究代表者：天野 良彦研究者番号：80273069Other2015～2016年度科学研究費助成事業（挑戦的萌芽研究）研究成果報告書 課題番号：15K14769 研究代表者：天野 良彦research repor
絶縁被覆磁性微粒子誘電体中分散複合材料巻線間充填型ＵＨＦ帯高Ｑインダクタの開発
No full text研究種目：若手研究(B)研究期間：2015～2016課題番号：15K18047研究代表者：曽根原 誠研究者番号：30456496Other2015～2016年度科学研究費助成事業（若手研究(B)）研究成果報告書 課題番号：15K18047 研究代表者：曽根原 誠research repor
高性能電磁波遮蔽材料の開発及び特定遮蔽周波数の実現
No full text研究種目：基盤研究(C)研究期間：2014～2016課題番号：26420721研究代表者：倪 慶清研究者番号：00252544Other2014～2016年度科学研究費助成事業（基盤研究(C)）研究成果報告書 課題番号：26420721 研究代表者：倪 慶清research repor
植物のフラボノイドＣ配糖化酵素の反応機構の解明
No full text研究種目：基盤研究(C)研究期間：2014～2016課題番号：26450120研究代表者：田口 悟朗研究者番号：70252070Other2014～2016年度科学研究費助成事業（基盤研究(C)）研究成果報告書 課題番号：26450120 研究代表者：田口 悟朗research repor
Transgenic Monkey Model of the Polyglutamine Diseases Recapitulating Progressive Neurological Symptoms
No full textAge-associated neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and the polyglutamine (polyQ) diseases, are becoming prevalent as a consequence of elongation of the human lifespan. Although various rodent models have been developed to study and overcome these diseases, they have limitations in their translational research utility owing to differences from humans in brain structure and function and in drug metabolism. Here, we generated a transgenic marmoset model of the polyQ diseases, showing progressive neurological symptoms including motor impairment. Seven transgenic marmosets were produced by lentiviral introduction of the human ataxin 3 gene with 120 CAG repeats encoding an expanded polyQ stretch. Although all offspring showed no neurological symptoms at birth, three marmosets with higher transgene expression developed neurological symptoms of varying degrees at 3–4 months after birth, followed by gradual decreases in body weight gain, spontaneous activity, and grip strength, indicating time-dependent disease progression. Pathological examinations revealed neurodegeneration and intranuclear polyQ protein inclusions accompanied by gliosis, which recapitulate the neuropathological features of polyQ disease patients. Consistent with neuronal loss in the cerebellum, brain MRI analyses in one living symptomatic marmoset detected enlargement of the fourth ventricle, which suggests cerebellar atrophy. Notably, successful germline transgene transmission was confirmed in the second-generation offspring derived from the symptomatic transgenic marmoset gamete. Because the accumulation of abnormal proteins is a shared pathomechanism among various neurodegenerative diseases, we suggest that this new marmoset model will contribute toward elucidating the pathomechanisms of and developing clinically applicable therapies for neurodegenerative diseases.ArticleeNeuro.4(2):e0250(2017)journal articl
新潟県柏崎市鵜川上流域におけるブユの発生状況とその防除対策．１．幼虫生息分布調査．
No full textIn order to control adult blackflies in the upper reaches of the Ukawa River in Kashiwazaki City, Niigata Prefecture, the present study was conducted on the larval habitats of blackfly at a total of 128 sites (a total of 319 sampling times) around the river, small stream and the waterway in the upper reaches of the Ukawa River Basin from June to October in 2013. A total of 12,805 individual blackfly larvae and pupae were captured during the investigation periods. The average number of larvae per site was 40.1 individuals/two investigators·5 minutes and we could collect blackfly larvae and pupae at almost all sampling sites. Noda was the highest capture area where we could collect 51.6 individuals/two investigators⋅5 minutes, followed by the Joujou Area. The fewest captures were in the Betsumata Area (19.5 individuals/two investigators⋅5 minutes). The dominant species was Simulium (Simulium) bidentatum (Shiraki, 1935) (279 total individuals, 34.8%), followed by Simulium (Simulium) quinquestriatum (Shiraki, 1935)(225, 28.1%), and Simulium (Simulium) japonicum Matsumura, 1931 (101, 12.6%).Article衛生動物.69(1):7-11(2018)journal articl
