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    922017 research outputs found

    Inflammatory Fabry cardiomyopathy demonstrated using simultaneous hybridised 18F-fluorodeoxyglucose positron emission tomography, cardiovascular magnetic resonance imaging

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    Using hybridised 18FDG-PET-CMR, we identify active myocardial inflammation, and demonstrate its relationship with late gadolinium enhancement, in Fabry disease. We demonstrate that LGE represents, at least in part, active myocardial inflammation, and identify an early inflammatory phenotype which may represent a therapeutic window before irreversible tissue injury and adaptation occurs

    Transforming Chinese consumers’ environmental concerns and eco-label awareness into willingness to pay for eco-labelled food products

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    The purpose of this paper is to model the antecedents of consumers’ willingness to pay for eco-labelled food products. The research utilises the Theory of Planned behaviour (TPB) to model the impact of consumers’ awareness of eco-label, environmental concern, belief in the environmental ability of eco-label and presence of children on their willingness to pay for eco-labelled food products. The study uses Structural Equational Modelling (SEM) and PROCESS macros, to test the moderated mediation model on a sample of 333 online responses. Findings suggest the impact of consumers’ environmental concerns and eco-label awareness on their willingness to pay for eco-labelled food products is partially mediated by consumers' belief in the environmental ability of these eco-labels. The relationship is also further moderated by the presence of children living in the household. The study establishes the value of consumers’ belief in the environmental ability of eco-labels and implies that communication strategies need to be carefully refined to provide consumers with more information about eco-labels and to emphasise the environmental ability of eco-labels utilised within the food industry as this can have an impact on their willingness to pay for these products especially for consumers with children living with them

    Zero-Shot Human-Object Interaction Recognition via Affordance Graphs

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    We propose a new approach for Zero-Shot Human-Object Interaction Recognition in the challenging setting that involves interactions with unseen actions (as opposed to just unseen combinations of seen actions and objects). Our approach makes use of knowledge external to the image content in the form of a graph that models affordance relations between actions and objects, i.e., whether an action can be performed on the given object or not. We propose a loss function with the aim of distilling the knowledge contained in the graph into the model, while also using the graph to regularise learnt representations by imposing a local structure on the latent space. We evaluate our approach on several datasets (including the popular HICO and HICO-DET) and show that it outperforms the current state of the art

    Impact of Two-Phase Flow Pattern on Solvent Vapour Extraction

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    Solvent Vapour extraction (Vapex) is a promising technology for in-situ heavy oil recovery from oil sands deposits. The prediction of oil recovery rates requires fundamental understanding of the pore-scale mechanisms and their impact on mass transfer and oil production. To bridge the gap between pore-scale mechanisms and macro scale recovery, a dynamic pore-network model for two-phase flow with mass transfer is developed. The impact of pressure gradient on two-phase flow pattern, mass transfer and oil production are investigated. It is found that at high capillary numbers, in viscous dominated flow, dissolved oil is moved in intermittent liquid clusters to the outlet of the network. This mechanism of interface renewal maintains a steep solvent mole fraction gradient at the interface and enhances mass transfer, resulting in high oil production. In capillary dominated flow, capillary fingering with low mass transfer and oil production are observed

    Transforming Chinese consumers’ environmental concerns and eco-label awareness into willingness to pay for eco-labelled food products

    No full text
    The purpose of this paper is to model the antecedents of consumers’ willingness to pay for eco-labelled food products. The research utilises the Theory of Planned behaviour (TPB) to model the impact of consumers’ awareness of eco-label, environmental concern, belief in the environmental ability of eco-label and presence of children on their willingness to pay for eco-labelled food products. The study uses Structural Equational Modelling (SEM) and PROCESS macros, to test the moderated mediation model on a sample of 333 online responses. Findings suggest the impact of consumers’ environmental concerns and eco-label awareness on their willingness to pay for eco-labelled food products is partially mediated by consumers' belief in the environmental ability of these eco-labels. The relationship is also further moderated by the presence of children living in the household. The study establishes the value of consumers’ belief in the environmental ability of eco-labels and implies that communication strategies need to be carefully refined to provide consumers with more information about eco-labels and to emphasise the environmental ability of eco-labels utilised within the food industry as this can have an impact on their willingness to pay for these products especially for consumers with children living with them

    Impact of abolishing primary care financial incentives on selected indicators of quality-of-care in Scotland: national controlled interrupted time series analysis

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    Objectives: The UK Quality and Outcomes Framework (QOF) primary care scheme pays financial incentives for achieving performance targets in chronic disease and was abolished in Scotland in 2016. We determined the impact of financial incentive withdrawal in Scotland on selected recorded quality-of-care, compared to England where financial incentives continued.Design: Interrupted time-series regression study of QOF indicator data.Setting: General practices in Scotland and England.Participants: People registered at general practices in Scotland and England.Intervention: Withdrawal of QOF financial incentives in Scotland at the end of the 2015-2016 financial year.Main outcome measures: Changes in quality-of-care at 1-year and 3-years post-abolition for 16 indicators measured annually from 2013-2014 to 2018-2019 financial years.Results: In Scotland, performance reduced significantly compared to England on 12 of the 16 quality-of-care indicators 1-year after QOF was abolished, and on 10 of 16 indicators 3-years after abolition. At 3-years, the absolute percentage-point difference in Scotland compared to England was largest for ‘tick-box’ recording of mental health care planning (-40.2 percentage-points, 95%CI -45.5 to -35.0) and diabetic foot screening (-22.8 percentage-points, 95%CI 33.9 to -11.7). However, there were also substantial reductions for intermediate outcomes including blood pressure control in patients with peripheral arterial disease (-18.5 percentage-points, 95%CI -22.1 to -14.9), stroke (-16.6 percentage-points, 95%CI -20.6 to -12.7), diabetes (-10.4 percentage-points, 95%CI -13.0 to -7.8), coronary heart disease (-12.8 percentage-points, 95%CI -14.9 to -10.8) and hypertension (-13.7 percentage points, 95% CI -19.4 to 7.9), and for HbA1c control in diabetes (-5.0 percentage-points, 95%CI 8.4 to -1.5 for HbA1c less than 75mmol/l). There were no significant differences between Scotland and England 3-years after incentive withdrawal for treatment indicators (influenza immunisation and antiplatelet/anticoagulant treatment).Conclusion: Removal of financial incentives in Scotland was associated with reductions in recorded quality of care for most indicators. Changes to pay-for-performance should be carefully designed and implemented to monitor and respond to any reductions in care quality. <br/

    Inflammatory Fabry cardiomyopathy demonstrated using simultaneous hybridised 18F-fluorodeoxyglucose positron emission tomography, cardiovascular magnetic resonance imaging

    No full text
    Using hybridised 18FDG-PET-CMR, we identify active myocardial inflammation, and demonstrate its relationship with late gadolinium enhancement, in Fabry disease. We demonstrate that LGE represents, at least in part, active myocardial inflammation, and identify an early inflammatory phenotype which may represent a therapeutic window before irreversible tissue injury and adaptation occurs

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