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Development of a Nursing Intervention Program to Promote Psychological Adjustment in Adult Women Diagnosed with Metastatic Breast Cancer
Get PDFThe purpose of this study was to develop a nursing intervention program to promote psychological adjustment
in adult women diagnosed with metastatic breast cancer (MBC) and to evaluate the validity and clinical
applicability of the program. The program was developed based on a review of studies of nursing interventions
for these patients and an empirical study of adult women diagnosed with MBC and undergoing cancer
pharmacotherapy. The survey was requested from 75 the Certified Nurse in Breast Cancer Nursing (BCN), and
44 of them (58.6 % response rate) consented to participate in the study. The method was a web-based survey
that asked about the validity and clinical applicability of the program. Descriptive statistics were used for
analysis. More than 90 % of the participants indicated that the program was appropriate. Regarding the clinical
applicability of the program, 59.1 % of participants responded “yes” and 34.1 % of participants responded “yes,
somewhat”. Participants provided comments that would be useful in practice and as educational material for
nurses. Some comments indicated the need for collaboration with Certified Nurse in Cancer. The results suggest
that the program can be considered as valid and clinically applicable from the point of view of Certified Nurse
in BCN. Future intervention studies should apply it clinically and test its effectiveness and usability.departmental bulletin pape
Translational research of boron neutron capture therapy for spinal cord gliomas using rat model
Get PDF大阪医科薬科大学博士（医学）2024doctoral thesi
S´os置換の逆置換のある2次元版の性質について
Get PDFIn the previous paper [Nagata and Takei, Bull. Fac. Pharm. OMPU, 2023], the authors introduced
the ranking table as a 2-dimensional version of the inverse of a S´os permutation and
discussed the 2D counterpart of the Sur´anyi bijection which relates the S´os permutations and
the sections generated by the Farey sequence. They also posed a question whether a certain
part of a ranking table determines entire table. In other papers [id., Bull. OUPS, 2021], [id.,
Bull. Fac. Pharm. OMPU, 2022], they studied the inverse of a S´os permutation. They introduced
some types as classes of permutations and reported relationships with the inverses of the S´os
permutations. In this paper, we introduce several types of maps from the direct product of two
finite sets of consecutive integers to a set of the same cardinality consisting of consecutive integers
and show that every ranking table belongs to all of the types introduced, including difference
equation type which is defined by certain difference equations of the double sequence in question.
Using properties of the types, we show an affirmative answer to the above question of determining
a ranking table from its part. We also report the details of the aforementioned relationships
between the ranking tables and the types as the result of numerical calculations by computers.
In particular, for all the finite cases for which the numerical calculations were performed, all
bijective maps of the difference equation type are ranking tables. Furthermore, we report results
of a one-dimensional version of our 2D discussion.departmental bulletin pape
Early Intervention of Steroid Therapy Improves Acute Unconsciousness due to Suspected Hashimoto’s Encephalopathy: A Case Report
Get PDFA 68-year-old man was admitted to our hospital with symptoms of dysrhythmia and high fever. He had been administered intravitreal aflibercept, an anti-vascular endothelial growth factor (anti-VEGF) drug, for diabetic retinopathy two days earlier. He was found unconscious and transferred to the intensive care unit (ICU). Computed tomography (CT), magnetic resonance imaging (MRI), and spinal fluid examination revealed no abnormal findings. Hashimotoʼs encephalopathy was suspected based on findings of low thyroid hormone levels, positive anti-thyroid peroxidase antibodies, and the exclusion of other diseases that present with acute unconsciousness. Although the possibility of encephalopathy due to anti-VEGF antibody therapy was considered, there were no imaging findings of cerebrovascular disorders associated with this therapy. Steroid therapy immediately improved his condition. He was discharged on the 20th day after ICU admission and subsequently transferred to a different hospital on the 77th day. Although autoantibody for anti-NH2-terminal of α-enolase was negative, Hashimotoʼs encephalopathy was considered the most likely differential diagnosis from a clinical perspective. When acute loss of consciousness due to autoimmune encephalopathy such as Hashimotoʼs encephalopathy is suspected, immediate steroid therapy should
be considered, rather than waiting for results of time-consuming tests.departmental bulletin pape
5‑Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapy
Get PDF大阪医科薬科大学博士（医学）2023doctoral thesi
Intraoperative Slow Train-of-four Monitoring Mode of the Orbicularis Oculi Muscle Prevents Postoperative Nausea and Vomiting
Get PDFStimulation of the stomach meridian, which consists of several stomach acupoints around the orbit, restores gastrointestinal peristalsis. We tested the hypothesis that postoperative nausea and vomiting (PONV) occur less in patients who receive intraoperative neuromuscular monitoring of orbicularis oculi muscles by facial nerve
stimulation (NOF). We retrospectively analysed patients who underwent elective gynaecological laparoscopic surgery under total intravenous anaesthesia. Predictors included age, body mass index, smoking history, history of PONV/motion sickness, duration of anaesthesia, existence of hysterectomy, analgesic adjuvants, and NOF using slow train-of-four (TOF) throughout anaesthesia. The outcome was the occurrence of PONV within 24 h. Binomial
logistic regression analysis was performed to investigate the potential associations between PONV and predictors. The incidence of PONV was 32.7 % (122/373). The occurrence of PONV was significantly positively associated with age (coefficient: 0.0382, p = .0071) and with hysterectomy (coefficient: 0.708, p = .0211), and significantly negatively associated with the presence of TOF (coefficient: −1.6506, p = .0077). Additionally, we assessed the
influence of TOF on the occurrence of PONV in the non-hysterectomy group. The occurrence of PONV was significantly negatively associated with the presence of TOF (coefficient: −2.1546, p = .011). Our results support the hypothesis that repetitive NOF ameliorates PONV in patients undergoing gynaecological surgery.departmental bulletin pape
