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Factors Influencing Novice Nurses’ Cognitive Appraisals of Traumatic Events in an Emergency Department at an Emergency and Critical Care Center
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Characteristics of Patients Diagnosed with Adrenal Insufficiency in the General Medicine Department of a University Hospital: A Single-Center Descriptive Study
Get PDFBackground: Adrenal insufficiency (AI) presents with several nonspecific symptoms that can lead to delayed
diagnosis, misdiagnosis, and decreased quality of life. This study aimed to identify the clinical profiles of patients
with AI who consulted to a university hospital general medicine department.
Methods: Cross-sectional data were retrospectively extracted from the medical records of patients with suspected
AI who visited the general medicine department at university hospitals in Japan between October 2015 and March
2019 and who underwent stimulation tests. Age–sex adjusted logistic regression analysis was performed with
various clinical signs as explanatory variables and AI diagnosis as the objective variable.
Results: Of the 122 study subjects, 82 (67.2 %) were women, 24 of whom were diagnosed as AI. Age–sex adjusted
logistic regression analysis revealed that the odds ratio (OR) per unit increase in random blood cortisol (OR: 0.74,
(95 % confidence interval [CI] 0.60–0.92)) was associated with a diagnosis of AI. However, the OR per unit
increase in random blood adrenocorticotropic hormone (OR: 0.97, 95 % CI 0.93–1.03) was not. General fatigue
(OR 5.5, 95 % CI 0.65–46.2), weight loss (OR 2.47, 95 % CI 0.78–7.82), and hypotension (OR 11.5, 95 % CI
1.05–125.6) were also associated with AI diagnosis.
Conclusions: Clinical signs such as general fatigue, weight loss and hypotension were significant predictors of
AI. The results suggest that several patients who visit the general medicine department at university hospitals in
Japan have conditions that are difficult to diagnose based on the test results. Prospective studies in general medicine
departments of several hospitals are required to validate the generalizability of these results.departmental bulletin pape
Changes in salivary microbiota due to gastric cancer resection and its relation to gastric fluid microbiota
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The actual state of respiratory function decline associated with allogeneic hematopoietic stem cell transplantation and consideration of nursing care to prevent respiratory function decline
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