Virginia Commonwealth University Medical Center

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    Saxophone Studio Recital

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    Studio RecitalSaxophone Studio RecitalStudents from the studio of Dr. Sheri Oyanwith James O\u27Brien and Russell Wilson, piano Tuesday, November 11, 2025 at 7:30 p.m.Recital HallJames W. Black Music Center1015 Grove Avenue | Richmond, Virgnini

    Faculty Recital, Neave Trio

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    Faculty RecitalNeave TriopresentsIn Her HandsSaturday, December 6, 2025 at 7:00 p.m.Sonia Vlahcevic Concert HallW.E. Singleton Center for the Performing Arts922 Park Avenue | Richmond, Virgini

    String Area Recital

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    Studio RecitalString Area RecitalTuesday, November 18, 2025 at 5:30 p.m.Recital HallJames W. Black Music Center1015 Grove Avenue | Richmond, Virgini

    Glitched Humanity: A Digital Media Arts Advocacy Project

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    This lesson includes an original sample project and website that directs students towards learning how to utilize digital glitch art to create advocacy or raise awareness for the social, cultural, environmental, or political issue of their choice. It is designed to engage students in critical thinking skills, cross-curricular connections, reflective writing, digital art making, group discussion, and peer review. Artists can use video and other media sources to explore the self-destructive tendencies of human nature (i.e. violence/war, consumption, and/or carelessness/environmental neglect) or other social, cultural, or political issues using digital manipulation, layered imagery, sound, and video.https://scholarscompass.vcu.edu/cstae_resource_early/1007/thumbnail.jp

    Junior Recital, Anais Knight, alto saxophone

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    Junior RecitalAnais Knight, alto saxophoneJames O\u27Brien, pianoFriday, November 21, 2025 at 6:00 p.m.Recital HallJames W. Black Music Center1015 Grove Avenue | Richmond, VirginiaThe presentation of this junior recital will fulfill in part the requirements for the Bachelor of Music degree in Education. Anais Knight studies the alto saxophone with Dr. Sheri Oyan

    Partners in Progress: How Non-Traditional Learners Perceive Organizational Support

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    Through in-depth, semi-structured interviews with eleven individuals who completed an undergraduate degree while employed full-time, this qualitative study explored how non-traditional students perceived the support provided by their employers in integrating educational and professional responsibilities. Participants, all 25 years or older at enrollment and employed full-time during their studies, shared experiences that revealed how organizational support facilitated or inhibited their academic success. Findings highlighted that support was multi-dimensional, encompassing structural, relational, and emotional-motivational factors, and that non-traditional students developed adaptive strategies to integrate school and work. The study provides insight into how workplace environments and cultures influence educational persistence and outcomes. Results may inform organizational policies and practices designed to better support employee-students pursuing higher education while working full-time

    A Case Study on National Branding via X: The Role of Government Public Relation Accounts in Shaping Saudi Youth Attitudes Towards Saudi Vision 2030

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    This study investigated how Saudi government public relations accounts on X influence Saudi youth perceptions of Vision 2030 as a national brand. It aimed to determine whether exposure to official digital communication strengthens awareness, national pride, and engagement among youth audiences, and to evaluate how message alignment, interactivity, and credibility shape their perceptions and participation. The research relied on two theoretical frameworks. Agenda Setting Theory explains how repeated exposure to official content influences public priorities, while Nation Branding Theory examines how state-led communication shapes national identity, legitimacy, and public attachment to national transformation initiatives. A mixed methods sequential explanatory design supported the achievement of the study objectives. The quantitative phase used an online survey completed by 400 Saudi youth aged 18 to 35 from both local universities and Saudi students studying in the United States. The qualitative phase included semi-structured interviews with ten participants selected from the survey pool to provide deeper interpretations of the patterns identified in the quantitative results. Quantitative analysis explored relationships between exposure to government communication, perception, engagement behavior, and national pride. Qualitative analysis used a thematic approach to identify recurring meanings that illustrated how youth interpret and experience Vision 2030 communication on X. The results showed that youth hold strong awareness of Vision 2030, positive perceptions of government communication efforts, and a high sense of national pride associated with official messaging. Message alignment with youth aspirations played an important role in shaping perception and emotional connection. Youth who interacted more frequently with official content tended to express stronger attachment and identification with Vision 2030. Differences appeared between participants inside Saudi Arabia and those living abroad, with domestic students showing higher levels of behavioral engagement and international students demonstrating wider interpretive diversity. The qualitative findings identified four core themes. Empowerment, national pride, digital participation, and cautious trust highlighted how youth view Vision 2030 as both a personal and collective reform initiative that connects individual ambition with national progress. The integration of both data strands confirmed strong convergence between numerical and narrative evidence. The findings showed that youth feel emotionally connected to Vision 2030 but may limit behavioral participation because of cultural expectations and limited opportunities for dialogic engagement on official platforms. Most of the proposed hypotheses were supported, affirming that government digital communication plays an important role in enhancing awareness, national unity, and emotional identification among Saudi youth. The study offers practical implications for improving government communication strategies. Authentic content, clear alignment with youth values, and interactive communication practices help build trust and increase participation. A communication style that reflects local cultural expectations while also appealing to global digital norms strengthens credibility and inclusivity. Several limitations were recognized. The sample does not represent all Saudi youth, the focus on a single platform excludes behavior on other digital channels, and the cross-sectional design captures perceptions from only one moment in Vision 2030’s timeline. Future research should use longitudinal and cross-platform designs to examine how youth engagement evolves as national communication strategies expand. This study contributes to communication and nation branding scholarship by demonstrating how digital government communication shapes public perception, emotional identity, and national unity. It presents a Saudi case model that shows how agenda-setting and nation-branding principles interact within a digital governance environment and provides evidence-based recommendations to enhance message resonance, transparency, and interactivity to support greater youth participation in Vision 2030. Keywords: Vision 2030, government communication, Saudi youth, nation branding, digital public relations, agenda-setting, social media, X platform

    Computational Modeling of Damage and Failure in Aerospace Materials due to High-Speed Weather Encounters

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    This work focused on establishing a computational strategy to model airborne particle (e.g. rain drop, ice) impact on aerospace materials at high-speeds in supersonic and hypersonic regimes. To achieve this goal, strain-rate dependent material models, namely Johnson-Cook and Johnson-Holmquist-Beissel, are incorporated into a non-ordinary state-based peridynamics framework. Validations and verifications were performed for benchmark shock-physics problems that present large deformation and material failure for ductile metals and brittle ceramics. A fluid-structure interaction framework was implemented by coupling the developed structural peridynamics solver with an immersed boundary method-based computational fluid dynamics solver to further investigate the effect of coupling mechanisms for water droplet impact on metallic targets. The resulting high-fidelity solutions highlighted the importance of full-coupling effects in the hypersonic regime. Finally, the applicability of the modeling approach was demonstrated on hypersonic weather encounter problems with a carbon-carbon composite which is a very relevant aerospace material with a high-temperature resistance

    EXPLORING THE ROLE OF HOST IMMUNE RESPONSES AND BACTERIAL SENSORY PATHWAYS IN THE DEVELOPMENT OF TREPONEMA DENTICOLA-MEDIATED PERIODONTAL DISEASE

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    Periodontitis is a chronic inflammatory disease driven by dysbiotic microbial communities and maladaptive host responses. Treponema denticola, a spirochete pathobiont, is strongly associated with disease severity. However, the molecular mechanisms underlying its interaction with host tissues and regulation of virulence remain incompletely understood. This work examines both the epithelial immune responses and bacterial transduction systems that shape T. denticola pathogenesis. Transcriptomic analysis of gingival keratinocytes revealed IL-36γ as the most highly induced cytokine following infection with T. denticola. Functional studies demonstrated that IL-36γ induction occurs in a dose- and time-dependent manner through TLR2/6 signaling, requiring the NF-κB, PI3K/Akt, and MAPK pathways. MSK1 was identified as a novel regulator of IL-36γ. Interestingly, mutants lacking dentilisin or Msp elicited increased IL-36γ expression, suggesting additional surface components also contribute to epithelial signaling. These findings position IL-36γ as a key cytokine in the epithelial response to T. denticola infection, highlighting the complexity of host–pathogen interactions at the gingival barrier. The AtcS/AtcR two-component system was also investigated as a regulator of T. denticola virulence. Transcriptomic profiling of the ΔatcS strain showed that AtcS is involved in the expression of genes related to transport, chemotaxis, and proteolysis. Loss of AtcS impaired motility, dentilisin activity, and epithelial adherence, while also reducing alveolar bone loss in vivo. These findings establish AtcS/R as a central signaling hub in spirochetal physiology and pathogenesis. Overall, these studies define IL-36γ as a major epithelial immune effector and AtcS as an essential bacterial regulator, advancing our understanding of T. denticola biology. Future research should focus on clarifying the mechanisms of IL-36γ secretion, the downstream targets of AtcR, and the potential of these pathways as therapeutic options in periodontal disease

    Targeting Epigenetic Regulators as a Novel Means to Prevent Triple Negative Breast Cancer Recurrence

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    Despite effective treatments, triple-negative breast cancer (TNBC) frequently recurs, causing mortality. Using multiple TNBC models, we studied recurrence mechanisms by examining recovery from clinically relevant concentrations of standard-of-care chemotherapies. Lineage barcode tracking shows recovery occurs stochastically, suggesting each cell in the initial population can recover. Single-cell RNA-sequencing of barcoded cells and Western blotting revealed epigenetic pathways altered during recovery from chemotherapy exposure. In cell culture, several epi-drugs and senolytic ABT-263 were most effective when administered after chemotherapy exposure, compared to combination or prior use. In contrast, only the KAT inhibitor MG149 controlled tumor growth when used sequentially in tumor-bearing mice. Analysis of post-chemotherapy tumors suggests the ineffectiveness of many drugs in vivo could be due to low levels of therapy-induced cell stress states, including senescence and autophagy. In vitro and in vivo studies showed sequential use of MG149 after Doxorubicin increased apoptosis, reduced cells in G2/M DNA damage checkpoint, and reduced expression of cell cycle inhibitors p21, p27, and p53. MG149\u27s efficacy depends on gain of function (GOF) p53 mutation and KAT8, which enhances pro-apoptotic factors PUMA, BAX, and BAK. This enhancement occurs through GOF p53 degradation, leading to tumor cell death following chemotherapy. Our findings indicate select epigenetic states form after chemotherapy exposure and demonstrate that sequential epigenetic therapies can be therapeutically targeted to prevent TNBC recurrence. This strategy could repurpose epi-drugs previously unsuccessful in controlling solid tumor growth when used with chemotherapy

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