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    662 research outputs found

    Verpackungen – funktional, effizient und recyclingfähig

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    Whey protein-based oxygen barrier coatings and modifications at lab and pilot scale

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    Biopolymer-based and recyclable materials are currently of high interest due to stricter legal requirements and consumer demand for more sustainable food packaging. However, many multilayer packaging materials are not commercially recyclable and are often not biodegradable or bio-based. Within the Horizon 2020 Project PRESERVE, whey protein coatings are being developed to produce among other things a bio-based and biodegradable oxygen barrier layer. This barrier coating based on whey protein isolate is additionally used as a separation layer for multilayer structures. Whey protein-based coatings have been successfully applied on multiple polymer films on a laboratory and pilot scale. This development will help address the demand for more sustainable food packaging by creating a biodegradable and recyclable oxygen barrier layer

    Heightened Cyber Vulnerability to Patients with Cardiac Implantable Electronic Devices

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    Cardiac implantable electronic devices (CIEDs) have shown to improve autonomy, quality of life, morbidity and mortality (relative reduction of mortality by 30% at 3 years follow-up) [1]. However, CIEDs possess a cyber vulnerability. With these exemplary safety concerns, we theorise: 1) Cybersecurity risks are difficult for medical institutions to plan (ambiguous nature of threat), which results in ineffective cyber defense measures, 2) Cyber threats can impair trust in the device, treatment plan and patient-provider relationship; and 3) As CIEDs “go” with the patient and the cyber risk can not be quantified, patients’ stress levels are higher from the perceived cyber threats than from a technical malfunction.From a literature review and subsequent position paper submission, the rationale for the research project was formulated. The methodology consists of two qualitative studies assessing both providers’ and patients’ perspectives of cybersecurity risks with CIEDs and a risk assessment of CIED manufacturer manuals. For designing the two qualitative studies, we postulated: 1) providers lack understanding about cybersecurity risks with CIEDs and thus do not include these risks in the informed consent due to either “not wanting to raise patients’ anxiety levels except for known serious adverse events”, or not wanting to “extend time with consenting patients for low-probability issues” [13] and 2) patients are not aware of the cyber risks with CIEDs. From the results of these studies, we plan to develop white papers to promote standards and guidelines for cybersecurity related risks with CIEDs to the inform consent-processes as well as manufacturers’ manuals

    Acinetobacter baumannii from grass: novel but non-resistant clones

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    Acinetobacter baumannii is one the most worrisome nosocomial pathogens, which has long been considered almost mainly as a hospital-associated bacterium. There have been some studies about animal and environmental isolates over the last decade. However, little effort has been made to determine if this pathogen dwells in the grass. Here, we aim to determine the evolutionary relationships and antibiotic resistance of clones of A. baumannii sampled from grass to the major human international clones and animal clones. Two hundred and forty genomes were considered in total from four different sources for this study. Our core and accessory genomic epidemiology analyses showed that grass isolates cluster in seven groups well differentiated from one another and from the major human and animal isolates. Furthermore, we found new sequence types under both multilocus sequence typing schemes: two under the Pasteur scheme and seven for the Oxford scheme. The grass isolates contained fewer antibiotic-resistance genes and were not resistant to the antibiotics tested. Our results demonstrate that these novel clones appear to have limited antibiotic resistance potential. Given our findings, we propose that genomic epidemiology and surveillance of A. baumannii should go beyond the hospital settings and consider the environment in an explicit One Health approach

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