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    Well Enough Alone: an Exploration of Feminine Solitude in Four American Novels

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    This dissertation studies representations of feminine solitude in four American novels: The Wonderful Wizard of Oz by L. Frank Baum, The Spoils of Poynton by Henry James, Tender is the Night by F. Scott Fitzgerald, and As I Lay Dying by William Faulkner. My approach is informed by the American literary tradition’s tendency, via Emerson and Thoreau, to present solitude as something particularly masculine. The case for analyzing feminine solitude is supported by many feminist critics, including Nina Baym and Carol Gilligan. These critics show an underrepresentation of women as contributing figures in the American literary canon and criticize the traditional casting of women as the weaker sex. My reading of each character under analysis in her mode of solitude takes shape through the ontological thought of Martin Heidegger, Friedrich Nietzsche, and Friedrich Hölderlin. In this dissertation, I consider female characters who are written by men in order to see how those authors most rooted in the American canon constructed the type of person unconsidered by society and underrepresented in literature: a willful, solitary woman

    Morals for Human Development in the Art of Lessing, Goethe, and Schiller: How Lessing, Goethe, and Schiller, Became Seminal to the Spread of Western Autonomy

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    Gotthold Ephraim Lessing, Johann Wolfgang von Goethe, and Johann Christoph Friedrich von Schiller, introduced a naturally occurring, non-heteronomous, independence and morality to the common man through their literary efforts in the last half of the eighteenth century. In a time of church and state censorship, when written and spoken Enlightenment efforts were directed toward universal freedom, when freedom for the masses, in aggregate, was an unacceptable idea, Lessing, Goethe, and Schiller proselytized individual freedom through self-development. They demonstrated, via didactive parables and other message carrying written vehicles, an awareness of self, i.e., the presence of an inherent, functional, personal spirit, whose engagement could lead to singular independence for every individual . They created literary role models that demonstrated independent behavior, and gave men and women the vision of new possibilities, and the potential for a fulfilled future. They hid these subversive parables as subplots, within acceptable plots, which would pass the censors. As well-known and popular German writers and critics, their literature, dramas, poetry, reviews, and essays, presented as entertainment, became conscious-raising tools for a literate public. A nexus of societal evolution, a literate public, and the art of Lessing, Goethe, and Schiller, formed a connection that enabled submissive men and women to develop agency. This dissertation contains in-text quotations and premises from parables, fables, etc., from the works of the canons of each, which demonstrate and teach the value and application of self- awareness, self-direction, and self-applied moral standards. The literature from which these quotations and premises are taken, the works which define their didactive intent, are Lessing’s, The Jews, Miss Sara Sampson, Laocoon, Emilia Galotti, and Nathan the Wise; Goethe’s, Maying, Prometheus, The Sorrows of Young Werther, and Egmont; Schiller’s, The Robbers, The Lessing’s, The Jews, Miss Sara Sampson, Laocoon, Emilia Galotti, and Nathan the Wise; Goethe’s, Maying, Prometheus, The Sorrows of Young Werther, and Egmont; Schiller’s, The Robbers, The Stage as a Moral Institution, Don Carlos, Letters on the Aesthetic Education of Man, and The Wallenstein Trilogy. plus On Epic and Dramatic Poetry, an essay Goethe and Schiller wrote jointly, and Correspondence Between Schiller and Goethe From 1794 to 1805, both of which Goethe published after Schiller’s death. This unique exposition extrapolated from correspondence, from autobiographies, and from biographical historiography, illustrates the heretofore unrecognized morals for human development in the art of Lessing, Goethe, and Schiller. As previously noted, this is a vital documentation that has been overlooked in the scholastic history of 18th century Enlightenment, the German Enlightenment, and the record of the contributions of Lessing, Goethe, and Schiller. A review of currently available publications about Lessing, Goethe, and Schiller, follows

    Targeting T Cells and a Novel Neurotrophic Factor to Treat Paclitaxel-induced Peripheral Neuropathy in Mice

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    Chemotherapy-induced peripheral neuropathy (CIPN) is a challenging condition to treat and arises due to the severe, dose-limiting toxicity of chemotherapeutic drugs such as paclitaxel. Thirty-70% of patients are affected by CIPN. Neurotoxicity associated with CIPN often results in damage to the peripheral nerves and dorsal root ganglia (DRG) and causes debilitating sensory deficits. Presently, there are no effective treatments to prevent or reduce CIPN. Here we sought to investigate two new approaches to treat CIPN. In the first approach we took advantage of immune cell interactions that occur in CIPN. Immune cells have been associated in the development and progression of the disease and disease resolution. We investigated the potential role of Inducible co- stimulatory molecule (ICOS) in the resolution of paclitaxel-induced peripheral neuropathy in mice. ICOS is an immune checkpoint molecule that is expressed on the surface of activated T cells and promotes proliferation and differentiation of T cells. In the second approach we investigated the potential antinociceptive effects of recombinant mouse Meteorin (rmMeteorin) using the paclitaxel-induced peripheral neuropathy model in male and female mice. Meteorin, a novel neurotrophic factor with an uncharacterized receptor, has been shown to mediate the reversal of neuropathic pain injured model. Our findings indicate that both approaches produce a robust antinociceptive effect in paclitaxel- induced peripheral neuropathy in mice. Modulating T cells into an anti-inflammatory phenotype, using ICOS, and using neurotrophic factors such as Meteorin could provide novel and effective therapeutics that are urgently needed for CIPN

    Transfer Learning for Large Scale Data-driven Modeling and Its Applications in Social Science

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    Proliferation of Internet technology in daily life has created numerous data. These data may come from a variety of sources, such as social networks, online businesses, sensors,military surveillance and so on. Generally speaking, these data could be either dynamic or static. Such huge amount of data, along with modern powerful computing capabilities, had pushed forward tremendous amount of applications in AI substantially, including computer vision, natural language processing, cyber-security, and etc. However, most applications still depends heavily on labeled data. The need of massive labeled data hinders the progress of AI research since the labeling process is very laborious and costly, and also goes against how human beings learn - human beings do not require many labeled data by drawing inferences.Transfer learning, as a popular machine learning paradigm recently, leverages knowledge from a source domain to effectively learn predictive models in a target domain which does not have sufficient labeled data. In this dissertation, we propose to investigate transfer learning techniques on an extensive of data-driven applications. First, we unveil a heterogeneous domain adaptation framework on multiple data stream settings, and we apply it to detect cyber attacks within the data stream. Then, we show that multitask learning on multiple domains may actually help with the classification and retrieval tasks on Computer Vision(CV) applications. After the two applications, we shift the research scope to the scenario of offline learning, and test our transfer learning algorithm on sentiment classification task in Natural Language Processing (NLP) domain. We extend the application scenarios even further to the political science domain. We discuss the potential of the modern Graph Neural Networks (GNN) and apply it to the applications of time series forecasting with additional spatial information. Such application includes a number of critical tasks in social science, including but not limited to peace research, transportation analysis, and epidemic spread modeling. We further address modeling challenges observed during the aforementioned applications, such as scalability, model complexity and etc

    Worldly Goods Made Intimate: Interpreting Andrea Mantegna’s Adoration of the Magi

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    In 1985, the J. Paul Getty Museum in Los Angeles, California purchased at auction a painting on canvas attributed to Italian Renaissance artist Andrea Mantegna. It sparked attention in the press as the most expensive painting purchase in the world to date, as well as for some scholarly criticism concerning the attribution of the work. Through vigorous conservation efforts by Andrea Rothe and the Getty Research Institute, The Adoration of the Magi was definitively attributed to Andrea Mantegna and the medium was established as distemper paint on linen canvas. From this point on, the painting has been the subject of much scholarly attention and questions have been raised about the patronage of the painting, the objects featured in the work, and the ethnicities of several key figures. Most scholars tend to suggest that the most likely patron is Isabella d’Este, due to her well-documented collections of objects similar to those painted into this work, and her marrying into the Gonzaga family of Mantua, who employed Andrea Mantegna for much of his career. This thesis uses these lines of questioning as a starting point to interpret how the artist meant for the painting to be viewed, and by whom. Through studying the mediums, size, compositional choices, and worldly people and things that make up this image – along with analysis of the collecting interests of his patron, Francesco II Gonzaga – this thesis suggests that Mantegna painted this work with Francesco in mind and intended to create an intimate and personalized portrayal of the moment of the Epiphany

    The Metacognitive Underpinnings of Confirmation Bias and Its Political Consequences

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    Numerous psychological studies on human reasoning attest to the mind’s pervasive tendency toward confirmation bias, consisting of a reluctance to change one’s mind by selectively integrating confirmatory evidence while underweighting contrary evidence. Among its pernicious effects is the political polarization it fosters, a result of the aggregation of like-minded individuals united by allegiance to a particular set of beliefs. The aim of this study is to shed light on how one’s ability to calibrate confidence to appropriately reflect available evidence, known as metacognitive sensitivity, reduces vulnerability to confirmation bias, along with facets of polarization it tends to foster in the political domain. The findings indicate that metacognitive sensitivity attenuates confirmation bias, operationalized as integration of disconfirmatory evidence, in the context of low-level perceptual decisions, but not when it comes to higher-order analytical decisions. When applied to political thought and behavior, individual differences in this capacity were incorporated into cognitive models demonstrating that metacognitive sensitivity attenuates dogmatic intolerance. However, it does not predict political ideological stance on the liberal-to-conservative spectrum, conspiratorial ideation, or vulnerability to misinformation representative of content found in online media. Measures that demonstrate lower susceptibility to confirmation bias (i.e., increased integration of disconfirmatory evidence) were associated with reduced levels of both right-wing and left-wing conspiratorial ideation as well as higher pro-democratic attitudes. Therefore, metacognitive sensitivity and resistance to confirmation bias together play a significant role in promoting more tolerant attitudes toward those who do not share one’s political beliefs while remaining open-minded and sensitive to information contrary to one’s strongly held beliefs

    Effects of Performance Shortfalls on Organizational Decisions and Outcomes

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    The performance context of an organization is an important factor in determining its strategy and outcomes following the strategic choices made. Specifically, negative performance contexts affect organizations more intensely, reducing the resources it has access to, changing how stakeholders are impacted, increasing scrutiny from the media, analysts and shareholders among others, and inviting evaluation and judgment of the decision-making of the CEO and other managers. In this dissertation, the multifaceted nature of performance shortfalls is explored across three essays covering different types of negative performance contexts, to provide a more complete understanding of how performance affect organizations. In the first essay, the focus is on the firm’s lifecycle stage of organizational decline, that presents a critical shortage of resources. We explore how organizations modify their CSR practices in such a context, as there could be both benefits and costs to engaging in CSR during decline. By distinguishing between different types of CSR, we show that firms navigate decline in a manner that incorporates both perspectives on CSR. In the second essay, we highlight the effect of a firm’s proximity to bankruptcy on CEOs’ decision-making based on different temporal perspectives. We suggest that a CEO’s career horizon (or time to retirement) is positively related to firm strategic change, and this effect decreases when a CEO past focus is higher. We further suggest that the dominating effect of objective time (CEO career horizon) versus subjective time (CEO past focus) depends on the firm’s closeness to bankruptcy, a situation that increases the salience of the CEO’s legacy in their decision-making. Finally, the third essay adds a social dimension to performance, looking at performance below social aspirations as a contextual condition. In this study, we show that CEOs’ social class backgrounds affect the characteristics of competitive repertoires they use in terms of complexity and non-conformity. As social comparison is an important aspect of competing in the market, we further study how performance below those of peers in the industry modifies these effects. Overall, this dissertation provides a bird’s eye view of performance shortfalls by exploring different types of negative performance contexts and how these affect different aspects of firm strategy including market, non-market and competitive strategy

    Essays on Empirical Corporate Finance

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    This dissertation consists of three essays on empirical corporate finance. The first essay, titled “Climate Change Salience and Firm Investment,” is included in Chapter 1. I hypothesize that firms are more likely to make investments that reduce their CO2 emissions intensity if the threat of climate change is more salient. To test this, I examine mergers and acquisitions (M&A) in the US from 2012-2021 and exploit exogenous variation in exposure to abnormally warm temperatures. Conditional on an M&A occurring, if the acquiror experienced abnormally warm temperatures at its headquarters within 6 months prior to the deal’s announcement, then the target has 15% lower estimated CO2 emissions intensity in the full sample of deals. The effect increases to 29% among deals where the acquiror has above median CO2 emissions intensity, as these are the types of firms most exposed to climate change transition costs. This paper shows that firms exhibit a behavioral bias known as attribute substitution in their adjustment to climate change, since they make an estimate of the impact based on local temperatures, an easily accessible proxy, rather than the true determining factors. The second essay, titled “Tax Avoidance through Cross-Border Mergers and Acquisitions” and coauthored with Jean-Marie Meier, is included in Chapter 2. We investigate 13,307 cross-border, tax-haven mergers and acquisitions (M&A) from 1990 to 2017, totaling 4.1trillionindealvalue,orabout304.1 trillion in deal value, or about 30% of total cross-border M&A volume. 2.4 of the 4.1 trillion is beyond what is predicted based on a gravity model with economic fundamentals. Tax-haven M&A result in 30.7 billion in recurring annual tax avoidance. To illustrate the magnitude, for a US firm with no prior cross-border, tax-haven M&A history, buying an Irish firm worth 5% of its total assets would result in an expected decline in its effective tax rate of 3.32 percentage points. For identification, we use a change in US tax law in 2004. Following haven acquisitions, firms are more likely to relocate their headquarters to havens. Our results document that tax avoidance through havens is a significant determinant of cross-border M&A. The third essay, titled “Improving the Measurement of Tax Residence: Implications for Research on Corporate Taxation” and coauthored with Jean-Marie Meier, is included in Chapter 3. We highlight an opportunity for improved measurement of a key data item in corporate tax research, a firm’s tax residence. Some countries define tax residence based on a firm’s location of incorporation, some on a firm’s location of headquarters, and some consider both locations. Because no firm-level tax residence database exists, studies typically apply a uniform assignment of either the location of incorporation, headquarters, or center of business activity. We use a novel algorithm that embeds the residency laws of 150 countries to accurately assign tax residence. We reassign the tax residence of a considerable fraction of firms relative to standard proxies, and provide evidence that reassignment significantly affects inferences. For instance, for cross-border mergers and acquisitions with a US acquiror, 16% of the deal value involves an acquiror that is reassigned. Moreover, reassigned firms are systematically different from other firms along several dimensions, including effective tax rates

    Paleomagnetism, Rock Magnetism, and Magnetic Fabric of Upper Permian Sedimentary Rocks and Early Jurassic Intrusions, Karoo Basin, South Africa, and of a Highly Distorted Oligocene Ignimbrite, East-central New Mexico

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    This dissertation includes three different projects that utilize paleomagnetic and rock magnetic techniques and principles to understand the thermal effect of magmatism on an older, host sedimentary rock sequence, its mineralogy and domain state, magnetization and remagnetization processes, to determine the magnetic polarity stratigraphy of Permian sedimentary rocks, and to evaluate the magnetic petrofabric of an Oligocene ignimbrite to understand its source and related transport history. Project #1 addresses the thermal effect of Early Jurassic Karoo large igneous province (LIPs) magmatism on a Permian sedimentary sequence cored in the Eastern Karoo Basin, South Africa. The study of the paleotemperature history of the host Permian sedimentary strata involved sampling the ~2320 m deep borecore intersected in the KARIN KWV-1 drilling project. The KWV-1 drilling experiment spudded about 10 km east of Willowvale town, Eastern Cape Province, and provides a unique natural laboratory for studying the effects of Karoo magmatism on the basin’s sedimentary sequence. Paleomagnetic and rock magnetic results from dolerite sills and host sedimentary strata reveal that single domain (SD) to multi-domain (MD) magnetite is the main magnetization carrier of the Karoo dolerite sills and host sedimentary strata sampled at distances greater than ½ the width of an adjacent sills. However, for host sedimentary strata sampled at distances < ½ the width of an adjacent sill, remanence is carried by both magnetite and SD pyrrhotite. Paleotemperature estimates based on the alteration index (A40) technique reveal that parts of the Ecca sedimentary sequence have remained at ambient, basinal burial temperatures, likely well below 250 ̊C. Thermal and alternating field (AF) demagnetization yield a well-defined interpretable response, with some data suggesting the preservation of early acquired Permian remanence in sections of the cored interval. Much of the sedimentary sequence has been subjected to a combination of thermoviscous/chemical remagnetization processes. Project #2 involves paleomagnetic and rock magnetic study of a ~50 m thick sequence (11 independent sites) of continental sedimentary rocks of the upper Permian/Lower Triassic Beaufort Group, lying above an Early Jurassic Karoo mafic sill (2 sites), exposed on Piersnaarbaken farm, Eastern Cape Province, to aid our understanding of the age of deposition of this section, which contains important palynologic information. Magnetic polarity results have been placed in a magnetostratigraphic context to infer that the age of deposition of these strata is part of the Illarawa mixed polarity zone (late Permian age), and in particular, part of the Elandsberg Member. Rock magnetic data show that magnetite is the main remanence carrier in these sedimentary rocks. Demagnetization experiments reveal that the natural remanent magnetization (NRM) of the host rocks has been partially overprinted by the Early Jurassic Karoo magmatism. Demagnetization data show that the NRM consists of two distinguishable components, referred to as component-1 and component-2. The component 1 is of NNW declination and moderate to steep negative inclination, unblocked in thermal demagnetization by ~ 460 ̊C and AF fields of << 90 mT. Component-2, on the other hand, is of dual polarity and is unblocked over a temperature range of ~ 460 ̊C to ~ 580 ̊C. The component-2 is of SSE declination at sites PBB4 and PBB5, and moderate to steep positive inclination, and is NNW declination and moderate to steep negative inclination at the remaining sites higher in the section. The dual polarity nature of Component-2 is interpreted to indicate that the sedimentary section was deposited after the Kiaman reverse polarity Superchron, and, possibly, during the latest Permian. Project #3 involves study of the anisotropy of magnetic susceptibility (AMS) and rock magnetism of the Palisades Tuff, Sierra Blanca, New Mexico. The Palisades tuff is of early Oligocene age and has been proposed to be the result of explosive eruption of quartz syenite magma that formed the nearby Three River Stock, based on geochemical similarity in terms of major and trace elements. Oriented block samples were collected from Palisades Tuff (PT) exposures at seven sites in the eastern Tularosa Basin. The magnetic fabric data derived from AMS measurements show that the PT exhibits both well-defined prolate and oblate fabrics. Rock magnetic experiments reveal that the magnetic mineralogy of the Palisades Tuff is dominated by pseudo-single to multi-domain magnetite, and hematite. The AMS data show that samples from some sites yield exclusively oblate fabrics, while samples from some yield exclusively prolate fabrics, and some are very mixed in behavior. For the sites with oblate fabrics, the inferred transport direction is east to northeast with few sample sites showing northwest and southwest directions. On the other hand, the inferred transport direction for sites with prolate grains and mixed prolate and oblate fabrics is west / northwest. The direction of transport inferred from the AMS data suggests that the Palisades tuff formed as a pyroclastic density current sourced from a caldera above Three River Stock, with varying degree of topographic modifications

    Prelinguistic/emerging Linguistic Gesture Use in Young Autistic Children

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    Autism is a complex neurodevelopmental disorder characterized by disruptions in early social communication skills. Early gesture plays a key role in prelinguistic/emerging linguistic communication and may provide insight into a child’s social communication skills before they acquire speech. As such, gesture is of particular interest for autism researchers. However, little is known about the gesture production of young autistic children from diverse racial/ethnic backgrounds in the early stages of gesture. In this dissertation, we explored the gesture production of young autistic children in the pre-linguistic/emerging linguistic stage of development within dyadic interactions across three studies. Data were gathered from culturally and socioeconomically diverse autistic children (ages 18-59 months) and a parent who participated in one of two more extensive randomized control trials of an early autism intervention. Study 1 explored the associations among race/ethnicity, parent gesture rate, and child gesture rate. Results indicated parents—like parents of non-autistic children—exhibited cross-racial/ethnic differences in gesture rate. However, child gesture rates were not related to the gesture rates of their parents. Consequently, children did not exhibit the same cross- racial/ethnic pattern of differences in gesture as their parents. Study 2 explored the relationship between elicitation task and child gesture. The rate and type of child gestures were compared across a naturalistic interaction with a parent and a standardized assessment of child communication administered by a research clinician. Results indicated (1) the most gestures and (2) the most developmentally advanced gestures were produced within structured interactions with clinicians that tempted child communication, while the fewest gestures were produced within play. Further, developmental differences emerged, such that greater differences between tasks were exhibited by children with receptive language ages greater than or equal to 9 months than by children below this developmental level. Study 3 analyzed the relationships among motor skill, social skill, and gesture in two ways: (1) the roles of gross motor, fine motor, and social skills (as measured by standardized assessments) on the rate of child gesture and (2) the relationship between the social sophistication of communication (level of communicative intention and coordination of communicative behaviors) and motor complexity of points. We found (1) standardized measures of social and gross motor (but not fine motor) skills explained unique variance in child gesture rate; (2a) coordination of communicative behaviors was positively related to motor complexity of gesture, with a small effect size; and (2b) motor complexity was related to the intentionality of communication (i.e., the degree to which the point had to first get/direct the adult’s attention) rather than to the social sophistication of the intention. Taken together, the work presented here underscores the importance of using diverse samples in autism research and interpreting results through a lens of cultural awareness. Our findings suggest an important role of motor skill in gesture production for young autistic children which has implications for future early intervention research

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