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Evaluation of an automatic dry eye test using MCDM methods and rank correlation
Dry eye is an increasingly common disease in modern society which affects a wide range of population and has a negative impact on their daily activities, such as working with computers or driving. It can be diagnosed through an automatic clinical test for tear film lipid layer classification based on color and texture analysis. Up to now, researchers have mainly focused on the improvement of the image analysis step. However, there is still large room for improvement on the machine learning side. This paper presents a methodology to optimize this problem by means of class binarization, feature selection, and classification. The methodology can be used as a baseline in other classification problems to provide several solutions and evaluate their performance using a set of representative metrics and decision-making methods. When several decision-making methods are used, they may offer disagreeing rankings that will be solved by conflict handling in which rankings are merged into a single one. The experimental results prove the effectiveness of the proposed methodology in this domain. Also, its general purpose allows to adapt it to other classification problems in different fields such as medicine and biology. © 2016 International Federation for Medical and Biological Engineerin
A collaborative approach for semantic time-based video annotation using gamification
Efficient access to large scale video assets, may it be our life memories in our hard drive or a broadcaster archive which the company is eager to sell, requires content to be conveniently annotated. Manually annotating video content is, however, an intellectually expensive and time-consuming process. In this paper we argue that crowdsourcing, an approach that relies on a remote task force to perform activities that are costly or time-consuming using traditional methods, is a suitable alternative and we describe a solution based on gamification mechanisms for collaboratively collecting timed metadata. Tags introduced by registered players are validated based on a collaborative scoring mechanism that excludes erratic annotations. Voting mechanisms, enabling users to approve or refuse existing tags, provide an extra guarantee on the quality of the annotations. The sense of community is also created as users may watch the crowd's favourite moments of the video provided by a summarization functionality. The system was tested with a pool of volunteers in order to evaluate the quality of the contributions. The results suggest that crowdsourced annotation can describe objects, persons, places, etc. correctly, as well as be very accurate in time
A novel stochastic reserve cost allocation approach of electricity market agents in the restructured power systems
In this paper, a new mechanism is proposed to apportion expected reserve costs between electricity market agents in the power system. The uncertainties of generation units, transmission lines, wind power generation and electrical loads are considered in this model. Hence, a Stochastic Unit Commitment (SUC) is used to apply the uncertainty of stochastic variables in the simultaneous energy and reserve market clearing problem. Moreover, electrical customers can participate in the electricity market based on their desired strategies. In this paper, a novel method is proposed to allocate reserve costs between GenCos, TransCos, electrical customers and wind farm owners. Consequently, market agents are responsible for paying a portion of the allocated expected reserve costs based on the economic metrics that are defined for the first,time in this paper. Finally, two cases including a 3-bus test system and IEEE-RTS are utilized to illustrate the performance of the proposed mechanism to share the expected reserve costs
Synthesis, spectroscopic characterization and biological evaluation of unsymmetrical aminosquarylium cyanine dyes
New unsymmetrical aminosquarylium cyanine dyes were synthesized and their potential as photosensitizers evaluated. New dyes, derived from benzothiazole and quinoline, were prepared by nucleophilic substitution of the corresponding O-methylated, the key intermediate that was obtained by methylation with CF3SO3CH3 of the related zwitterionic unsymmetrical dye, with ammonia and methylamine, respectively. All three news dyes herein described displayed intense and narrow bands in the Vis/NIR region (693-714 nm) and their singlet oxygen formation quantum yields ranged from 0.03 to 0.05. In vitro toxicity, in Caco-2 and HepG2 cells, indicated that dark toxicity was absent for concentrations up to 5 mu M (for the less active dye) or up to 1 mu M (for the two more active dyes). The three dyes present potential as photosensitizers, differing in irradiation conditions and period of incubation in the presence of irradiated dye. The less active dye needs a longer irradiation period to exhibit phototoxicity which is only evident after longer period of contact with cells (24 h). However, the remaining two more active dyes produce higher phototoxicity, even at shorter incubation periods (1 h), with shorter irradiation time (7 min). Although in different extents, these dyes show promising in vitro results as photosensitizers
Towards Improved Understanding of the Applicability of Uncertainty Forecasts in the Electric Power Industry
Using POI functionality and accessibility levels for delivering personalized tourism recommendations
The Role of the Pallidothalamic Fibre Tracts in Deep Brain Stimulation for Dystonia: A Diffusion MRI Tractography Study
Background: Deep Brain Stimulation (DBS) of the Globus pallidus internus (GPi) is gold standard treatment in medically refractory dystonia. Recent evidence indicates that stimulation effects are also due to axonal modulation and affection of a fibre network. For the GPi, the pallidothalamic tracts are known to be the major motor efferent pathways. The aim of this study is to explore the anatomic vicinity of these tracts and DBS electrodes in dystonia applying diffusion tractography. Methods: Diffusion MRI was acquired in ten patients presenting for DBS for dystonia. We applied both a conventionally used probabilistic tractography algorithm (FSL) as well as a probabilistic streamline tracking approach, based on constrained spherical deconvolution and particle filtering with anatomic priors, to the datasets. DBS electrodes were coregistered to the diffusion datasets. Results: We were able to delineate the pallidothalamic tracts in all patients. Using the streamline approach, we were able to distinguish between the two sub-components of the tracts, the ansa lenticularis and the fasciculus lenticularis. Clinically efficient DBS electrodes displayed a close anatomic vicinity pathway of the pallidothalamic tracts, and their course was consistent with previous tracer labelling studies. Although we present only anatomic data, we interpret these findings as evidence of the possible involvement of fibre tracts to the clinical effect in DBS. Electro-physiological intraoperative recordings would be needed to complement our findings. In the future, a clear and individual delineation of the pallidothalamic tracts could optimize the stereotactic process of optimal electrode localization. (C) 2016 Wiley Periodicals, Inc
On the use of stochastic local search techniques to revise first-order logic theories from examples
Theory Revision from Examples is the process of repairing incorrect theories and/or improving incomplete theories from a set of examples. This process usually results in more accurate and comprehensible theories than purely inductive learning. However, so far, progress on the use of theory revision techniques has been limited by the large search space they yield. In this article, we argue that it is possible to reduce the search space of a theory revision system by introducing stochastic local search. More precisely, we introduce a number of stochastic local search components at the key steps of the revision process, and implement them on a state-of-the-art revision system that makes use of the most specific clause to constrain the search space. We show that with the use of these SLS techniques it is possible for the revision system to be executed in a feasible time, while still improving the initial theory and in a number of cases even reaching better accuracies than the deterministic revision process. Moreover, in some cases the revision process can be faster and still achieve better accuracies than an ILP system learning from an empty initial hypothesis or assuming an initial theory to be correct
Multimode interference-based fiber sensor in a cavity ring-down system for refractive index measurement
This work reports a multimode interference-based fiber sensor in a cavity ring-down system (CRD) for sensing temperature-induced refractive index (RI) changes of water. The sensing head is based in multimodal interference (MMI) and it is placed inside the fiber loop cavity of the CRD system. A modulated laser source was used to send pulses down into the fiber loop cavity and an erbium-doped fiber amplifier (EDFA) was placed in the fiber ring to provide an observable signal with a reasonable decay time. The behavior of the sensing head to temperature was studied due to its intrinsic sensitivity to said parameter - a sensitivity of -1.6x10(-9) mu s/degrees C was attained. This allowed eliminating the temperature component from RI measurement of water and a linear sensitivity of 580 mu s/RIU in the RI range of 1.324-1.331 was obtained. The use of a MMI fiber sensor in the proposed CRD configuration allowed achieving a sensitivity similar to 4-fold than that obtained with a tilted fiber Bragg grating and similar to 2-fold than that when a micrometric channel inscribed in the fiber was used