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CO482 corn inbred line
Get PDFCO482 is an early maturing 2700CHU (68-70 days to 50% silk emergence and pollen shed) yellow, semi-dent inbred line with mixed heterotic group that combine well with stiff stalk and iodent testers to produce hybrids with high grain yield. The inbred line has moderate resistance to rust and intermediate resistance to goss’s wilt and is susceptible to gibberella ear rot and northern corn leaf blight. This inbred line is most suitable for short season regions of North America with CHU ranging from 2500 to 2700.The presentation of the authors' names and (or) special characters in the title of the pdf file of the accepted manuscript may differ slightly from what is displayed on the item page. The information in the pdf file of the accepted manuscript reflects the original submission by the author
Physiological monitoring for occupational heat stress management: recent advancements and remaining challenges
Get PDFOccupational heat stress poses a major threat to worker health and safety that is projected to worsen with global climate warming. To manage these adverse effects, most industries rely on administrative controls (stay times and work-to-rest allocations) that are designed to limit the rise in body core temperature in the ‘average’ individual. However, due to the extensive inter- and intra-individual variation in thermoregulatory function, these administrative controls will result in some individuals having their work rate and productivity unnecessarily restricted (false positives), while others may be subject to rises in heat strain that compromise health (false negatives). Physiological monitoring has long been touted as a more effective approach for individualized protection from excessive heat stress. This has led to extensive interest in the use of wearable technology for heat stress management from both the scientific community and manufacturers of wearable devices, which has accelerated in the past decade. In this review, we evaluate the merits of the recent and emerging approaches to manage occupational heat strain with wearable physiological monitors. Against this background, we then describe the issues that we perceive to be unresolved regarding the use of wearable heat strain monitors and the research efforts needed to address those issues. Particular emphasis is directed to the efficacy of existing physiological indicators of heat strain, how to define upper limits for those indicators and the efforts required to rigorously validate emerging wearable heat strain monitoring devices.The presentation of the authors' names and (or) special characters in the title of the pdf file of the accepted manuscript may differ slightly from what is displayed on the item page. The information in the pdf file of the accepted manuscript reflects the original submission by the author
Making It Count: Pilgrimage and the Enumeration of Publics
Get PDFAn activity that is widespread but rarely closely examined in studies of pilgrimage is the enumeration of pilgrims (and related visitors) to shrines and their environs. Such “biopolitics of hosting” can play a significant role in mobilising the religious imagination of shrine administrators, especially in contexts of apparently growing secularity. Number can be deployed by professional hosts to represent undifferentiated visiting publics in terms of spiritual possibility. In these terms, precision in statistics is likely to be less useful than figures that can be viewed through a distanced lens of potentiality. These ideas are developed through an examination of the Christian pilgrimage site of Walsingham, in eastern England
A Proposal of Literacy as Synergy: Developing Written Literacy through Triadic Reciprocal Causation with the Currere Workshop within Secondary Learning
Get PDFLiteracy as synergy (LAS), a construct I developed, examines the triadic reciprocality between literacy, external stimuli, and internal processes. A currere-inspired writer’s workshop was developed using LAS to create an authentic and meaningful written literacy program that can be applied within formal learning contexts. My study’s purpose is to propose LAS and the currere workshop as a way of integrating LAS within formal learning contexts. 10 participants of New Victory Assembly Church participated in the currere workshop. Data was collected over nine workshop sessions. Codes and themes were extracted thematically. The findings reveal that the meaningfulness of my participants’ experiences was communicated effectively through their engagement in the currere workshop and that factors such as the stream of consciousness method, modelling, and incorporating their external influences increased their written communication and highlighted their unique voices and identities. My study has meaningful implications on curriculum makers, practicing educators, and future researchers.M.A
Canadian Expert Consensus Recommendations for the Diagnosis and Management of Glioblastoma: Results of a Delphi Study
Get PDFGlioblastoma is the most common and aggressive malignant brain tumor in adults, with an increasing incidence and a poor prognosis. Current challenges in glioblastoma management include rapid tumor growth, limited treatment effectiveness, high recurrence rates, and a significant impact on patients’ quality of life. Given the complexity of glioblastoma care and recent advancements in diagnostic and treatment modalities, updated guidelines are needed in Canada. This Delphi study aimed to develop Canadian consensus recommendations for the diagnosis, classification, and management of newly diagnosed and recurrent glioblastoma. A multidisciplinary panel of 14 Canadian experts in glioblastoma care was convened, and a comprehensive literature review was conducted to synthesize evidence and formulate initial recommendations. Consensus was achieved through three Delphi rounds, in which panelists rated their agreement with recommendation statements on a five-point Likert scale. Statements with ≥75% agreement were accepted, and others were revised for re-voting. Final recommendations were formulated based on the consensus level, strength of evidence, clinical expertise, and consideration of the Canadian healthcare context. These recommendations aim to standardize glioblastoma diagnosis and classification across Canada, provide evidence-based guidance for optimal treatment selection, integrate novel therapies, and enhance the overall quality of care for glioblastoma patients
Overcoming Pseudomonas aeruginosa in Chronic Suppurative Lung Disease: Prevalence, Treatment Challenges, and the Promise of Bacteriophage Therapy
Get PDFPseudomonas aeruginosa, a multidrug-resistant pathogen, significantly impacts patients with chronic respiratory conditions like cystic fibrosis (CF) and non-CF chronic suppurative lung disease (CSLD), contributing to progressive lung damage and poor clinical outcomes. This bacterium thrives in the airway environments of individuals with impaired mucociliary clearance, leading to persistent infections and increased morbidity and mortality. Despite advancements in management of these conditions, treatment failure remains common, emphasising the need for alternative or adjunctive treatment strategies. Bacteriophage therapy, an emerging approach utilising viruses that specifically target bacteria, offers a potential solution to combat P. aeruginosa infections resistant to conventional antibiotics. This review examines the prevalence and disease burden of P. aeruginosa in CF and CSLD, explores the mechanisms behind antibiotic resistance, the promising role of bacteriophage therapy and clinical trials in this sphere
The Interactive Role of Cyclic Vertical and Torsional Stresses on the Instability of Low Plasticity Soils based on Hollow Cylinder Testing
Get PDFSoil instability and potential failure under principal stress rotation (PSR) require greater attention than ever before due to increased operation of heavier and longer high-speed trains. This study focuses on the interplay between cyclic vertical stress and torsional shear stress on the failure condition of a low plasticity subgrade soil, facilitated by a hollow cylinder (HC) apparatus. Combined vertical and torsional loading significantly influences strain response, with increasing torsional stress leading to higher strain accumulation. Moreover, the data indicate that an increase in torsional shear stress is generally accompanied by a swift rise in the EPWP and a corresponding decrease in the soil stiffness. In view of this, a novel parameter, the overall stiffness degradation index (δ_o) that simultaneously captures both the vertical and torsional shear effects under principal stress rotation is proposed as an early indicator of instability. In addition, a normalized torsional stress ratio (NTSR), which is the ratio of the amplitude of torsional shear stress to twice confining pressure, is introduced to assess the impact of torsional shear stress. Whereby, higher NTSR values correlate with premature inception of failure. These experimental results provide new insights for a better understanding of soil instability under simulated railway loading.The presentation of the authors' names and (or) special characters in the title of the pdf file of the accepted manuscript may differ slightly from what is displayed on the item page. The information in the pdf file of the accepted manuscript reflects the original submission by the author
Justice Rosalie Silberman Abella: A Life of Firsts
Get PDFJustice Abella was appointed to the Supreme Court of Canada in 2004, making history as the first Jewish woman appointed to Canada’s top court. Born in a displaced persons camp in Stuttgart, Germany, she had a storied career before joining Canada’s top court as a practicing lawyer, a family court judge, law reformer (Chair of the Ontario Law Reform Commission), labour adjudicator, law professor, appeal court justice, and commission of inquiry head (her 1984 federal Royal Commission on Equality in Employment created the term and concept of "employment equity.") She was elected to the Royal Society of Canada in 1997, to the American Academy of Arts and Sciences in 2007, and to the American Philosophical Society in 2018. In 2020, she was awarded the Knight Commander’s Cross of the Order of Merit by the President of Germany. She is a graduate of the Royal Conservatory of Music, has judged the Giller Literary Prize, moderated a Prime Ministerial Leader’s Debate, and spellbound audiences around the globe with her oratory.
Explore what it takes to drive change through the remarkable achievements of the first Jewish woman appointed to Canada’s Supreme Court, featuring contributions from dozens of national and international scholars, lawyers, judges, and artists
68Ga-DOTATATE PET/CT in the Initial Staging of Well-Differentiated Gastroenteropancreatic and Non-Gastroenteropancreatic Neuroendocrine Tumors: Results of a Prospective Registry
Get PDFBackground and Objectives: At diagnosis, the initial staging of well-differentiated neuroendocrine tumors (WD NETs) aids in treatment planning. The somatostatin receptor (SSTR)-PET has been recommended for staging of WD NETs although limited data are available on its impact on non-gastroeneteropancreatic (GEP) NETs. The main purpose of this study was to compare the stage migration after the addition of SSTR-PET to the workup of patients at the initial staging of GEP NETs to those with non-GEP NETs, and its potential impact on patient management. Methods: This prospective study included patients with WD NETs at initial staging. Demographic data, results of conventional and SSTR-PET staging, and SUVmax were recorded. Three panels of experts assessed the potential impact of SSTR-PET to management. Results: There were 482 patients, including 376 with gastroenteropancreatic (GEP) NETs and 106 non-GEP NETs with a median SUVmax of 34.7 [Q1, Q3: 22.8, 59.1]) and 19.0 [Q1, Q3: 7.9, 39.8]), respectively; p < 0.001. The discordant M-stage was recorded in 111/473 patients (23.5%). PET suggested a higher stage in 78/369 GEP NETs (21.1%), including the detection of extrahepatic metastatic disease in 42/114 (36.8%) patients with liver metastases only on CI. For non-GEP NETs, PET suggested a higher stage in 10/104 (9.6%) and CI suggested a higher stage in 15/104 (14.4%), with CI detecting liver metastases more frequently. The potential impact to management for patients with discordant M-stage was scored as moderate to high between 57/101 (56.4%) and 79/101 (78.2%) of patients. Conclusions: One in five patients are upstaged following SSTR-PET, more frequently with GEP NETs than others. SSTR-PET identifies extrahepatic metastatic disease in >1/3 of patients with presumed liver-only metastases on CI. Stage migration following SSTR-PET may result in frequent moderate or significant management change
S-MDEG Minimum Viable Metadata Recommendations Release 1.0
Get PDFThe guidelines developed by the Minimum Viable Metadata sub-group of the Scholaris Metadata and Discovery Expert Group (S-MDEG) offer a practical, community-informed approach to working with metadata in DSpace. These documents provide recommendations for minimum and standard metadata requirements within the Scholaris service. This includes clear documentation for standard Qualified Dublin Core as implemented in DSpace 7, along with metadata mappings for additional namespaces such as OpenAIRE, thesis/ETD-MS, and basic custom metadata fields